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The map label for this gene is 238917452

Identifier: 238917452

GI number: 238917452

Start: 1588985

End: 1590235

Strand: Reverse

Name: 238917452

Synonym: EUBELI_01530

Alternate gene names: NA

Gene position: 1590235-1588985 (Counterclockwise)

Preceding gene: 238917453

Following gene: 238917451

Centisome position: 74.16

GC content: 37.89

Gene sequence:

>1251_bases
ATGGTAAATGCAATTTTAAGAACATATATTCCTGATGATTGGAGTGTAATCACGTTAGGAAATTATGCACAGATTTTTAG
AGGCGGCTCACCAAGACCTATTCAAGCATTTTTGACGACAAGTGATCAAGGTGTTAATTGGATAAAAATTGGCGACGTAG
GTGAGGAAGATAAATTCATAAAATCAACTGAAGAAAAAATCGTACCAGAGGGAGTTTCATGTTCTAGAATGGTATTCAGA
GGTGATCTTATTCTCTCTAATTCGATGAGCTATGGACGTCCATATATCATGAATATCGAGGGTTGCATTCATGATGGTTG
GCTCGTCATTCAAAAATATGACAGAGTCTTTGATAGAGACTATTTGTATTATGCGCTTAGTTCGGGTTTGACAATGAAAC
AGTATGTTGCAATGGCAGCTGGGAGCAGTGTTCAGAACCTAAATAAGGAGAAAGTTTCAAAAGTAGTTCTACCTTGTCCA
AGGATATCTGAACAAAAATCAATAGCAGAAGTTTTATCGGATATAGATACACTAATTATAGATTTGAAAAAAATTATTCG
TAAGAAAAAAGATATTCGCCAAGGAACAATGCAAATGCTTGTAACTGGAAAGAAACGATTAAGTGGATTTGATGGAAACT
GGAGAGTGACGACTCTAGATCGGCTCTGCTATATAGTGACAAAGCAAACAGGATTTGATTATAGCGCAGAGATTAAGCCG
TCGCTTGTGACTACACCACAAATTGGAACCATCCCATTCATTCAAAATAAGGATTTTGAGGCGTTTGATATCAATTACAA
TACAGACTTTTTCATTCCCTATGATGTAGCAGAAAAGTATCCCAGGATCCTTCTGAATGAGGTGTGTCTACTGATATCAA
TTTCAGGGCGCATAGGAAACGTTGCAATCTTTGATAATGAGCAGACTTCGTTCGCTGGAGGAGCGGTTGGTATTGCAAAA
CTGTATGAGCCTGAATTGGCAAGTTGGTGCATGCTGTATTTGTCTAGCAAGGACGGACAAGAGCAGATTTTCTCCAATGA
AAAAGTTGGAGCACAGCATAATTTGACGGTAGCTGATGTCCGAAAACTCGAAATCAAGATGCCTGCAAAGTCAGAGAGAG
AAGCTATTATCAAAGTTTTAACGGATATGAATGATGAAATCGAAGTCCTTGAAGAAAAATTAGATAAGTATCAAAAAATC
AAACAAGGTATGATGGACGAATTGCTGACCGGCAAGGTCAGGTTAGTGTAA

Upstream 100 bases:

>100_bases
AACTTTCTGAGAGATACGAGGATACACTGCCGGAGCTTGACAAAGTCACTACTGAATATGAGGCAAAGGTAAAGTCTCAT
CTTGAAAGGATGGGATTCAA

Downstream 100 bases:

>100_bases
GGAGGTGCCTGTCAGATGAGTATTGGTGATGCCGAAATTAAAACACAGGAAAGAGTGATCCGTTTCTTTAAAGAACCGGA
GATCTTGGGCTACCAGTATA

Product: type I restriction enzyme

Products: NA

Alternate protein names: S.MjaXIP; Type I restriction enzyme MjaXIP specificity protein; S protein [H]

Number of amino acids: Translated: 416; Mature: 416

Protein sequence:

>416_residues
MVNAILRTYIPDDWSVITLGNYAQIFRGGSPRPIQAFLTTSDQGVNWIKIGDVGEEDKFIKSTEEKIVPEGVSCSRMVFR
GDLILSNSMSYGRPYIMNIEGCIHDGWLVIQKYDRVFDRDYLYYALSSGLTMKQYVAMAAGSSVQNLNKEKVSKVVLPCP
RISEQKSIAEVLSDIDTLIIDLKKIIRKKKDIRQGTMQMLVTGKKRLSGFDGNWRVTTLDRLCYIVTKQTGFDYSAEIKP
SLVTTPQIGTIPFIQNKDFEAFDINYNTDFFIPYDVAEKYPRILLNEVCLLISISGRIGNVAIFDNEQTSFAGGAVGIAK
LYEPELASWCMLYLSSKDGQEQIFSNEKVGAQHNLTVADVRKLEIKMPAKSEREAIIKVLTDMNDEIEVLEEKLDKYQKI
KQGMMDELLTGKVRLV

Sequences:

>Translated_416_residues
MVNAILRTYIPDDWSVITLGNYAQIFRGGSPRPIQAFLTTSDQGVNWIKIGDVGEEDKFIKSTEEKIVPEGVSCSRMVFR
GDLILSNSMSYGRPYIMNIEGCIHDGWLVIQKYDRVFDRDYLYYALSSGLTMKQYVAMAAGSSVQNLNKEKVSKVVLPCP
RISEQKSIAEVLSDIDTLIIDLKKIIRKKKDIRQGTMQMLVTGKKRLSGFDGNWRVTTLDRLCYIVTKQTGFDYSAEIKP
SLVTTPQIGTIPFIQNKDFEAFDINYNTDFFIPYDVAEKYPRILLNEVCLLISISGRIGNVAIFDNEQTSFAGGAVGIAK
LYEPELASWCMLYLSSKDGQEQIFSNEKVGAQHNLTVADVRKLEIKMPAKSEREAIIKVLTDMNDEIEVLEEKLDKYQKI
KQGMMDELLTGKVRLV
>Mature_416_residues
MVNAILRTYIPDDWSVITLGNYAQIFRGGSPRPIQAFLTTSDQGVNWIKIGDVGEEDKFIKSTEEKIVPEGVSCSRMVFR
GDLILSNSMSYGRPYIMNIEGCIHDGWLVIQKYDRVFDRDYLYYALSSGLTMKQYVAMAAGSSVQNLNKEKVSKVVLPCP
RISEQKSIAEVLSDIDTLIIDLKKIIRKKKDIRQGTMQMLVTGKKRLSGFDGNWRVTTLDRLCYIVTKQTGFDYSAEIKP
SLVTTPQIGTIPFIQNKDFEAFDINYNTDFFIPYDVAEKYPRILLNEVCLLISISGRIGNVAIFDNEQTSFAGGAVGIAK
LYEPELASWCMLYLSSKDGQEQIFSNEKVGAQHNLTVADVRKLEIKMPAKSEREAIIKVLTDMNDEIEVLEEKLDKYQKI
KQGMMDELLTGKVRLV

Specific function: The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. In the presence of the R subunit the complex can also act as an endonuclease, binding to

COG id: COG0732

COG function: function code V; Restriction endonuclease S subunits

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-I restriction system S methylase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000055 [H]

Pfam domain/function: PF01420 Methylase_S [H]

EC number: NA

Molecular weight: Translated: 47067; Mature: 47067

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNAILRTYIPDDWSVITLGNYAQIFRGGSPRPIQAFLTTSDQGVNWIKIGDVGEEDKFI
CCCCHHHHHCCCCCEEEEECCHHHHHCCCCCCCEEEEEEECCCCCCEEEECCCCCCCHHH
KSTEEKIVPEGVSCSRMVFRGDLILSNSMSYGRPYIMNIEGCIHDGWLVIQKYDRVFDRD
HHHHHHHCCCCCCCCEEEEECCEEEECCCCCCCCEEEEECCEECCCEEEEEHHHHHHCCC
YLYYALSSGLTMKQYVAMAAGSSVQNLNKEKVSKVVLPCPRISEQKSIAEVLSDIDTLII
CEEEHHHCCCHHHHHHHHHCCCHHHHCCHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHH
DLKKIIRKKKDIRQGTMQMLVTGKKRLSGFDGNWRVTTLDRLCYIVTKQTGFDYSAEIKP
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHEEEEEEECCCCCCCCCCCC
SLVTTPQIGTIPFIQNKDFEAFDINYNTDFFIPYDVAEKYPRILLNEVCLLISISGRIGN
CEECCCCCCCCCEEECCCCEEEEECCCCCEEEEHHHHHHHHHHHHHHEEEEEEECCCCCE
VAIFDNEQTSFAGGAVGIAKLYEPELASWCMLYLSSKDGQEQIFSNEKVGAQHNLTVADV
EEEECCCCCCCCCCCHHHHHHCCHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCHHHE
RKLEIKMPAKSEREAIIKVLTDMNDEIEVLEEKLDKYQKIKQGMMDELLTGKVRLV
EEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEC
>Mature Secondary Structure
MVNAILRTYIPDDWSVITLGNYAQIFRGGSPRPIQAFLTTSDQGVNWIKIGDVGEEDKFI
CCCCHHHHHCCCCCEEEEECCHHHHHCCCCCCCEEEEEEECCCCCCEEEECCCCCCCHHH
KSTEEKIVPEGVSCSRMVFRGDLILSNSMSYGRPYIMNIEGCIHDGWLVIQKYDRVFDRD
HHHHHHHCCCCCCCCEEEEECCEEEECCCCCCCCEEEEECCEECCCEEEEEHHHHHHCCC
YLYYALSSGLTMKQYVAMAAGSSVQNLNKEKVSKVVLPCPRISEQKSIAEVLSDIDTLII
CEEEHHHCCCHHHHHHHHHCCCHHHHCCHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHH
DLKKIIRKKKDIRQGTMQMLVTGKKRLSGFDGNWRVTTLDRLCYIVTKQTGFDYSAEIKP
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHEEEEEEECCCCCCCCCCCC
SLVTTPQIGTIPFIQNKDFEAFDINYNTDFFIPYDVAEKYPRILLNEVCLLISISGRIGN
CEECCCCCCCCCEEECCCCEEEEECCCCCEEEEHHHHHHHHHHHHHHEEEEEEECCCCCE
VAIFDNEQTSFAGGAVGIAKLYEPELASWCMLYLSSKDGQEQIFSNEKVGAQHNLTVADV
EEEECCCCCCCCCCCHHHHHHCCHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCHHHE
RKLEIKMPAKSEREAIIKVLTDMNDEIEVLEEKLDKYQKIKQGMMDELLTGKVRLV
EEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]