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The map label for this gene is sigC [H]

Identifier: 238917440

GI number: 238917440

Start: 1572839

End: 1573357

Strand: Reverse

Name: sigC [H]

Synonym: EUBELI_01518

Alternate gene names: 238917440

Gene position: 1573357-1572839 (Counterclockwise)

Preceding gene: 238917441

Following gene: 238917439

Centisome position: 73.38

GC content: 35.26

Gene sequence:

>519_bases
GTGTTGAGTGATGACGAATTAGTGGAACAGATTCTACTTGGAAAGGAAAATGTAGCAGAAGAATTGATAAAACGCTATTA
TACATCTATTTTACGTTACTGTAGGTGGCATTGCTCCAATCTGGAAAAAGCAGAAGACCTGACTCAGGAAACATTTTTGC
AGTTGTTTAAGAATTTATCCGGATATAAAGGGAAAAAGAAATTTAAGGCTTATCTATACACGATTGCAAATCATTTATGT
ATTGATGAAAGTAGGAAGGTTGAGTTTTATCCATTAGAAGATGAAGAAAATATAGCGCATGAGTATAACGACATAGTTCG
GCTAGAGGATAGGGCAGAGATAAGCTATTTTTTGAATTTTTTATCATCAGAACAAAGGGAAGCAGTCATTCTACGCTTTG
GAGAACAACTTAGTTTTGGAGAGATTGCAAAAGTGATGGGATGCAATATGCGAACAGCACAAAGCAGGGTTCGTAATGCT
TTAAAAATTATGAGAAAGGAGCAGGAAAATGAAAGATAA

Upstream 100 bases:

>100_bases
TGATGGGCAAAAAAGAAAAAATGAGGAATCTTTTAATCATTTTAAGTGCATAACCCGTTATTATATATATACAGATATTC
AATGGAAAGGAGTCTGATGC

Downstream 100 bases:

>100_bases
AAATTTGAAGGGCTATTTACAGCAATCTTTAGGAGAGGAAGTACAACCTAAAAGATTAGAGGAAACGATTAAGCTTTGCA
CTGAAATTGTACGAGAACAG

Product: ECF subfamily RNA polymerase sigma-70 factor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 172; Mature: 172

Protein sequence:

>172_residues
MLSDDELVEQILLGKENVAEELIKRYYTSILRYCRWHCSNLEKAEDLTQETFLQLFKNLSGYKGKKKFKAYLYTIANHLC
IDESRKVEFYPLEDEENIAHEYNDIVRLEDRAEISYFLNFLSSEQREAVILRFGEQLSFGEIAKVMGCNMRTAQSRVRNA
LKIMRKEQENER

Sequences:

>Translated_172_residues
MLSDDELVEQILLGKENVAEELIKRYYTSILRYCRWHCSNLEKAEDLTQETFLQLFKNLSGYKGKKKFKAYLYTIANHLC
IDESRKVEFYPLEDEENIAHEYNDIVRLEDRAEISYFLNFLSSEQREAVILRFGEQLSFGEIAKVMGCNMRTAQSRVRNA
LKIMRKEQENER
>Mature_172_residues
MLSDDELVEQILLGKENVAEELIKRYYTSILRYCRWHCSNLEKAEDLTQETFLQLFKNLSGYKGKKKFKAYLYTIANHLC
IDESRKVEFYPLEDEENIAHEYNDIVRLEDRAEISYFLNFLSSEQREAVILRFGEQLSFGEIAKVMGCNMRTAQSRVRNA
LKIMRKEQENER

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released [H]

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR013325
- InterPro:   IPR013324 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 20438; Mature: 20438

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSDDELVEQILLGKENVAEELIKRYYTSILRYCRWHCSNLEKAEDLTQETFLQLFKNLS
CCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHC
GYKGKKKFKAYLYTIANHLCIDESRKVEFYPLEDEENIAHEYNDIVRLEDRAEISYFLNF
CCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LSSEQREAVILRFGEQLSFGEIAKVMGCNMRTAQSRVRNALKIMRKEQENER
HCCHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLSDDELVEQILLGKENVAEELIKRYYTSILRYCRWHCSNLEKAEDLTQETFLQLFKNLS
CCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHC
GYKGKKKFKAYLYTIANHLCIDESRKVEFYPLEDEENIAHEYNDIVRLEDRAEISYFLNF
CCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LSSEQREAVILRFGEQLSFGEIAKVMGCNMRTAQSRVRNALKIMRKEQENER
HCCHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]