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The map label for this gene is panE [C]

Identifier: 238917390

GI number: 238917390

Start: 1521059

End: 1522024

Strand: Reverse

Name: panE [C]

Synonym: EUBELI_01467

Alternate gene names: 238917390

Gene position: 1522024-1521059 (Counterclockwise)

Preceding gene: 238917391

Following gene: 238917389

Centisome position: 70.98

GC content: 40.89

Gene sequence:

>966_bases
ATGTATATGAAGATAAAATCAGTGGCAGTATTTGGAGCAGGAGCAGTTGGCTCTTATGTTATATGGGGACTTTCAGAAAA
GAAGGATATAAGTTTAAGCGTTATTGCAAAGGGTGAAAGAGCGGAAAGACTTAAGGCAGAGGGCTGCTTAATTAATGGGA
AGACATACCACCCGGAGGTATTGACACCTGAGGAGGCAAAGGGTGTTGACCTTCTTATTGTGTCATTAAAGTATGGCGCA
CTTGCAGGTGCATTAGATGATATTAAGGAAGTTGTCAGTGAGAATACAATTGTCATGAGCCTTATGAACGGCGTTGACAG
TGAAGAGATAATATCTACTAAGATAGATAAATCACATATCATTTATTCACTTATAAAGGTGGCGTCACACCGCGAAGAAA
AGGAATATGTGTTCAATCCTGAGACTACAATAGGCATTATATATGGCGAGGAAGCTGCACCATTTGAGAGTGAGAGAGTT
GCGGCAATAAGAGATTTATTTGATGGAACAGGACTTAATTACAGAGTGACTGACTGTATCAAAGAAGAGATATGGAGCAA
GTATAGACTTAACATCTGTAACAATCTTCCACAGGCTATTATTGGAGCAGGTGTTGGCTGCTATACAGACAGTGAGCATA
TGAAAGCAATCAGCGAAGGATTACGTAAGGAGGTTGAAGCAGTTGCTCTTGCAAAAGGCATTGATATGAGCAGATGCGCA
GGTACATCAAGCCGTGGAAGTGCTGTTCCGCCAACAGCAAGATATTCAACACTGCAGGACATTGATGCAGGCAGACATAC
AGAGATAGATATGTTCTCCGGCACAATGATGCGTATGGGAAAAGAACTTGGAATTGCTACACCATATAACGAATATACAT
ATCACATCATCAAGGCACTTGAAGAAAAGAATGATGGCGTGTTTGATTATGATGAGAACAGTGAGGCTGTGACTTATTCT
AAGTAG

Upstream 100 bases:

>100_bases
GATTTTGAAGAGGGCGATATTGTAGGAAGATAAAAGCATTTGACGCGGAAAGAAGGGAAGTGTATATATATTTGAAGAAA
TTACAAAGATTGAGAGGAAA

Downstream 100 bases:

>100_bases
TGAATGACAAGAATTAATAATTCCTGTTGACATATACCCACATAGGGTATATTATACATCATGTAAATGAGATATACCCT
ACCAGGGTATGTTACATCCA

Product: 2-dehydropantoate 2-reductase

Products: NA

Alternate protein names: Ketopantoate reductase; KPA reductase; KPR [H]

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MYMKIKSVAVFGAGAVGSYVIWGLSEKKDISLSVIAKGERAERLKAEGCLINGKTYHPEVLTPEEAKGVDLLIVSLKYGA
LAGALDDIKEVVSENTIVMSLMNGVDSEEIISTKIDKSHIIYSLIKVASHREEKEYVFNPETTIGIIYGEEAAPFESERV
AAIRDLFDGTGLNYRVTDCIKEEIWSKYRLNICNNLPQAIIGAGVGCYTDSEHMKAISEGLRKEVEAVALAKGIDMSRCA
GTSSRGSAVPPTARYSTLQDIDAGRHTEIDMFSGTMMRMGKELGIATPYNEYTYHIIKALEEKNDGVFDYDENSEAVTYS
K

Sequences:

>Translated_321_residues
MYMKIKSVAVFGAGAVGSYVIWGLSEKKDISLSVIAKGERAERLKAEGCLINGKTYHPEVLTPEEAKGVDLLIVSLKYGA
LAGALDDIKEVVSENTIVMSLMNGVDSEEIISTKIDKSHIIYSLIKVASHREEKEYVFNPETTIGIIYGEEAAPFESERV
AAIRDLFDGTGLNYRVTDCIKEEIWSKYRLNICNNLPQAIIGAGVGCYTDSEHMKAISEGLRKEVEAVALAKGIDMSRCA
GTSSRGSAVPPTARYSTLQDIDAGRHTEIDMFSGTMMRMGKELGIATPYNEYTYHIIKALEEKNDGVFDYDENSEAVTYS
K
>Mature_321_residues
MYMKIKSVAVFGAGAVGSYVIWGLSEKKDISLSVIAKGERAERLKAEGCLINGKTYHPEVLTPEEAKGVDLLIVSLKYGA
LAGALDDIKEVVSENTIVMSLMNGVDSEEIISTKIDKSHIIYSLIKVASHREEKEYVFNPETTIGIIYGEEAAPFESERV
AAIRDLFDGTGLNYRVTDCIKEEIWSKYRLNICNNLPQAIIGAGVGCYTDSEHMKAISEGLRKEVEAVALAKGIDMSRCA
GTSSRGSAVPPTARYSTLQDIDAGRHTEIDMFSGTMMRMGKELGIATPYNEYTYHIIKALEEKNDGVFDYDENSEAVTYS
K

Specific function: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid [H]

COG id: COG1893

COG function: function code H; Ketopantoate reductase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ketopantoate reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR003710
- InterPro:   IPR013752
- InterPro:   IPR013332
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02558 ApbA; PF08546 ApbA_C [H]

EC number: =1.1.1.169 [H]

Molecular weight: Translated: 35269; Mature: 35269

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYMKIKSVAVFGAGAVGSYVIWGLSEKKDISLSVIAKGERAERLKAEGCLINGKTYHPEV
CEEEEEEEEEECCCCCCCEEEECCCCCCCCEEEEEECCCHHHHHHHCCEEECCCCCCCCC
LTPEEAKGVDLLIVSLKYGALAGALDDIKEVVSENTIVMSLMNGVDSEEIISTKIDKSHI
CCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHCCCCEEEHHHHCCCHHHHHHHHCCHHHH
IYSLIKVASHREEKEYVFNPETTIGIIYGEEAAPFESERVAAIRDLFDGTGLNYRVTDCI
HHHHHHHHHCCCCCCEEECCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCEEHHHHH
KEEIWSKYRLNICNNLPQAIIGAGVGCYTDSEHMKAISEGLRKEVEAVALAKGIDMSRCA
HHHHHHHHHHHHHHCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHC
GTSSRGSAVPPTARYSTLQDIDAGRHTEIDMFSGTMMRMGKELGIATPYNEYTYHIIKAL
CCCCCCCCCCCCHHHHHHHHCCCCCCCEEHHHCCHHHHHHHHCCCCCCCHHHHHHHHHHH
EEKNDGVFDYDENSEAVTYSK
HHCCCCCCCCCCCCCEEEECC
>Mature Secondary Structure
MYMKIKSVAVFGAGAVGSYVIWGLSEKKDISLSVIAKGERAERLKAEGCLINGKTYHPEV
CEEEEEEEEEECCCCCCCEEEECCCCCCCCEEEEEECCCHHHHHHHCCEEECCCCCCCCC
LTPEEAKGVDLLIVSLKYGALAGALDDIKEVVSENTIVMSLMNGVDSEEIISTKIDKSHI
CCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHCCCCEEEHHHHCCCHHHHHHHHCCHHHH
IYSLIKVASHREEKEYVFNPETTIGIIYGEEAAPFESERVAAIRDLFDGTGLNYRVTDCI
HHHHHHHHHCCCCCCEEECCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCEEHHHHH
KEEIWSKYRLNICNNLPQAIIGAGVGCYTDSEHMKAISEGLRKEVEAVALAKGIDMSRCA
HHHHHHHHHHHHHHCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHC
GTSSRGSAVPPTARYSTLQDIDAGRHTEIDMFSGTMMRMGKELGIATPYNEYTYHIIKAL
CCCCCCCCCCCCHHHHHHHHCCCCCCCEEHHHCCHHHHHHHHCCCCCCCHHHHHHHHHHH
EEKNDGVFDYDENSEAVTYSK
HHCCCCCCCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]