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The map label for this gene is clpX

Identifier: 238917376

GI number: 238917376

Start: 1507125

End: 1508393

Strand: Reverse

Name: clpX

Synonym: EUBELI_01453

Alternate gene names: 238917376

Gene position: 1508393-1507125 (Counterclockwise)

Preceding gene: 238917377

Following gene: 238917375

Centisome position: 70.35

GC content: 38.46

Gene sequence:

>1269_bases
ATGGCAGGCAGAAATATTGACGAGAAGCTTAGATGCTCATTCTGTAATAAGACACAGGATCAGGTTAAAAAGCTGATCGC
AGGACATAATGGCGTTTACATTTGTGATGAATGTGTAGAAATATGCAGCGATATCCTTGATGAAGAGTTTGAAACAGAGG
CAGATGCAAAAGAAGTGGTTGATGGAATGAATATCAACCTGCTTAAGCCAAAGCAGATAAAAGAATTTCTTGATGATTAT
GTTATAGGACAGGATGAAGCAAAGAAGGTTCTTGCGGTTGCTGTATATAATCATTATAAGAGGATAATGTCACAGTCTGA
TCTGGATGTAGAGTTACAGAAGAGTAATATTCTTATGCTTGGACCAACAGGTTCAGGAAAGACATTTCTTGCACAGAATC
TTGCAAGGCTTCTTAATGTACCTTTTGCAATTGCAGATGCTACAACTCTTACGGAAGCCGGATATGTAGGTGAGGATGTT
GAGAATATCCTTTTGAAGCTTATTCAGGCTGCGGATTATGATGTTGAAAAAGCACAATATGGTATTATATATATTGATGA
GATAGATAAGATTACTAAGAAGTCAGAAAATGTTTCCATAACAAGAGATGTATCTGGCGAGGGCGTACAGCAGGCTCTTC
TTAAGATATTAGAGGGAACAATAGCATCAGTTCCACCACAGGGAGGAAGAAAGCATCCACAGCAGGAGCTTATTCCAATT
GATACAACTAATATTCTTTTCATATGTGGTGGTGCATTTGACGGACTCGAGAAGATTATTGAATCAAGAATGGATAAGAG
TTCAATTGGTTTCAACTCTGAACTTAAGGAAAAGAGCAACGACGATGTTGGAGAGATGTTCCATAAGGCACTTCCACAGG
ATCTTATCAAATTCGGTCTTATTCCTGAGTTTGTAGGCCGAGTTCCGGTTGTTGTTTCATTAGATTCACTTGATGAGGAA
GCACTTGTGAGAATTCTAAAAGAGCCTAAGAATGCTATTATAAAGCAGTATCAGGCACTTTTTGGACTTGATGAAGTAGC
ACTTGAGTTTACGGATGAAGCTGTTGAGGCAGTTGCCCATAAGAGTTTTGAGAGAAAGACAGGAGCAAGAGGCTTACGTT
CAATCTTAGAATCTGTCATGAATGAAGTAATGTATGAGATTCCGTCAGATGAAACAATATCAAAATGTATAATAACTAAG
GAAGCTGTAGAAGGAAGCGCAAAGCCTCTGTTAGAATACAGAACGGATGCTGTAAAAAAAGCACAGTAA

Upstream 100 bases:

>100_bases
AGGAAGATGCCTGCAGATAATACATTTGCAGGTGTCTCCCTTGTTTTTGTGTGATAAGCGAACCTTTATTTAAAGGATTT
ATAGTGATTTGGAGGATAGT

Downstream 100 bases:

>100_bases
CGAAATTAATTCAGGCGGGCTGTTCATGATGGACGGTCCGTTTTTTAGATAGAGAGGAATATATGAGTAACAAATATGAT
AGACATTATCCAGCTATTCC

Product: ATP-dependent Clp protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 422; Mature: 421

Protein sequence:

>422_residues
MAGRNIDEKLRCSFCNKTQDQVKKLIAGHNGVYICDECVEICSDILDEEFETEADAKEVVDGMNINLLKPKQIKEFLDDY
VIGQDEAKKVLAVAVYNHYKRIMSQSDLDVELQKSNILMLGPTGSGKTFLAQNLARLLNVPFAIADATTLTEAGYVGEDV
ENILLKLIQAADYDVEKAQYGIIYIDEIDKITKKSENVSITRDVSGEGVQQALLKILEGTIASVPPQGGRKHPQQELIPI
DTTNILFICGGAFDGLEKIIESRMDKSSIGFNSELKEKSNDDVGEMFHKALPQDLIKFGLIPEFVGRVPVVVSLDSLDEE
ALVRILKEPKNAIIKQYQALFGLDEVALEFTDEAVEAVAHKSFERKTGARGLRSILESVMNEVMYEIPSDETISKCIITK
EAVEGSAKPLLEYRTDAVKKAQ

Sequences:

>Translated_422_residues
MAGRNIDEKLRCSFCNKTQDQVKKLIAGHNGVYICDECVEICSDILDEEFETEADAKEVVDGMNINLLKPKQIKEFLDDY
VIGQDEAKKVLAVAVYNHYKRIMSQSDLDVELQKSNILMLGPTGSGKTFLAQNLARLLNVPFAIADATTLTEAGYVGEDV
ENILLKLIQAADYDVEKAQYGIIYIDEIDKITKKSENVSITRDVSGEGVQQALLKILEGTIASVPPQGGRKHPQQELIPI
DTTNILFICGGAFDGLEKIIESRMDKSSIGFNSELKEKSNDDVGEMFHKALPQDLIKFGLIPEFVGRVPVVVSLDSLDEE
ALVRILKEPKNAIIKQYQALFGLDEVALEFTDEAVEAVAHKSFERKTGARGLRSILESVMNEVMYEIPSDETISKCIITK
EAVEGSAKPLLEYRTDAVKKAQ
>Mature_421_residues
AGRNIDEKLRCSFCNKTQDQVKKLIAGHNGVYICDECVEICSDILDEEFETEADAKEVVDGMNINLLKPKQIKEFLDDYV
IGQDEAKKVLAVAVYNHYKRIMSQSDLDVELQKSNILMLGPTGSGKTFLAQNLARLLNVPFAIADATTLTEAGYVGEDVE
NILLKLIQAADYDVEKAQYGIIYIDEIDKITKKSENVSITRDVSGEGVQQALLKILEGTIASVPPQGGRKHPQQELIPID
TTNILFICGGAFDGLEKIIESRMDKSSIGFNSELKEKSNDDVGEMFHKALPQDLIKFGLIPEFVGRVPVVVSLDSLDEEA
LVRILKEPKNAIIKQYQALFGLDEVALEFTDEAVEAVAHKSFERKTGARGLRSILESVMNEVMYEIPSDETISKCIITKE
AVEGSAKPLLEYRTDAVKKAQ

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family

Homologues:

Organism=Homo sapiens, GI7242140, Length=331, Percent_Identity=50.1510574018127, Blast_Score=320, Evalue=2e-87,
Organism=Escherichia coli, GI1786642, Length=407, Percent_Identity=62.6535626535627, Blast_Score=514, Evalue=1e-147,
Organism=Escherichia coli, GI1790366, Length=104, Percent_Identity=45.1923076923077, Blast_Score=101, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI71982908, Length=322, Percent_Identity=47.2049689440994, Blast_Score=290, Evalue=1e-78,
Organism=Caenorhabditis elegans, GI71982905, Length=322, Percent_Identity=47.2049689440994, Blast_Score=289, Evalue=2e-78,
Organism=Caenorhabditis elegans, GI71988663, Length=402, Percent_Identity=40.0497512437811, Blast_Score=261, Evalue=7e-70,
Organism=Caenorhabditis elegans, GI71988660, Length=253, Percent_Identity=42.2924901185771, Blast_Score=182, Evalue=3e-46,
Organism=Saccharomyces cerevisiae, GI6319704, Length=410, Percent_Identity=39.2682926829268, Blast_Score=258, Evalue=9e-70,
Organism=Drosophila melanogaster, GI24648291, Length=331, Percent_Identity=48.036253776435, Blast_Score=309, Evalue=2e-84,
Organism=Drosophila melanogaster, GI24648289, Length=331, Percent_Identity=48.036253776435, Blast_Score=309, Evalue=2e-84,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CLPX_EUBE2 (C4Z1T5)

Other databases:

- EMBL:   CP001104
- RefSeq:   YP_002930893.1
- GeneID:   7957114
- GenomeReviews:   CP001104_GR
- KEGG:   eel:EUBELI_01453
- OMA:   CGKSQEQ
- HAMAP:   MF_00175
- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603
- PANTHER:   PTHR11262:SF4
- SMART:   SM00382
- TIGRFAMs:   TIGR00382

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX

EC number: NA

Molecular weight: Translated: 46767; Mature: 46636

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGRNIDEKLRCSFCNKTQDQVKKLIAGHNGVYICDECVEICSDILDEEFETEADAKEVV
CCCCCCCHHHHHHHHCCCHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHCCCCCHHHHH
DGMNINLLKPKQIKEFLDDYVIGQDEAKKVLAVAVYNHYKRIMSQSDLDVELQKSNILML
CCCCCEEECHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCEEEE
GPTGSGKTFLAQNLARLLNVPFAIADATTLTEAGYVGEDVENILLKLIQAADYDVEKAQY
CCCCCCHHHHHHHHHHHHCCCHHHHCHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHC
GIIYIDEIDKITKKSENVSITRDVSGEGVQQALLKILEGTIASVPPQGGRKHPQQELIPI
CEEEEECHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHCCCCC
DTTNILFICGGAFDGLEKIIESRMDKSSIGFNSELKEKSNDDVGEMFHKALPQDLIKFGL
CCCCEEEEECCCHHHHHHHHHHHCCHHCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHCC
IPEFVGRVPVVVSLDSLDEEALVRILKEPKNAIIKQYQALFGLDEVALEFTDEAVEAVAH
CHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KSFERKTGARGLRSILESVMNEVMYEIPSDETISKCIITKEAVEGSAKPLLEYRTDAVKK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHC
AQ
CC
>Mature Secondary Structure 
AGRNIDEKLRCSFCNKTQDQVKKLIAGHNGVYICDECVEICSDILDEEFETEADAKEVV
CCCCCCHHHHHHHHCCCHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHCCCCCHHHHH
DGMNINLLKPKQIKEFLDDYVIGQDEAKKVLAVAVYNHYKRIMSQSDLDVELQKSNILML
CCCCCEEECHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCEEEE
GPTGSGKTFLAQNLARLLNVPFAIADATTLTEAGYVGEDVENILLKLIQAADYDVEKAQY
CCCCCCHHHHHHHHHHHHCCCHHHHCHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHC
GIIYIDEIDKITKKSENVSITRDVSGEGVQQALLKILEGTIASVPPQGGRKHPQQELIPI
CEEEEECHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHCCCCC
DTTNILFICGGAFDGLEKIIESRMDKSSIGFNSELKEKSNDDVGEMFHKALPQDLIKFGL
CCCCEEEEECCCHHHHHHHHHHHCCHHCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHCC
IPEFVGRVPVVVSLDSLDEEALVRILKEPKNAIIKQYQALFGLDEVALEFTDEAVEAVAH
CHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KSFERKTGARGLRSILESVMNEVMYEIPSDETISKCIITKEAVEGSAKPLLEYRTDAVKK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHC
AQ
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA