BacMap

Definition	Eubacterium eligens ATCC 27750 chromosome, complete genome.
Accession	NC_012778
Length	2,144,190

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The map label for this gene is dnaJ

Identifier: 238917284

GI number: 238917284

Start: 1397461

End: 1398588

Strand: Reverse

Name: dnaJ

Synonym: EUBELI_01359

Alternate gene names: 238917284

Gene position: 1398588-1397461 (Counterclockwise)

Preceding gene: 238917285

Following gene: 238917283

Centisome position: 65.23

GC content: 43.97

Gene sequence:

>1128_bases
ATGGCAGATAAGAGAGATTATTATGAAGTCCTTGGCGTGCCTAAGGATGCCGATGACGCTGCTATTAAGAAAGCATACAG
ACAACTTGCAAAGAAATATCATCCTGATATGAATCCAGGGGATAAAGAAGCTGAAATAAAATTCAAAGAGGCTTCTGAAG
CTTATGCGGTGTTAAGCGATGCTGAAAAGAGAAGACAGTATGACCAGTTTGGCCATGCCGCATTTGAAGGCGGAGCAGGT
GGAGCTGGAGCAGGTGGCTTCGATTTCGATTTTGGTGACATGGGAGATATTTTCGGAGATCTCTTTGGCGGTATGTTCGG
AGGCGGCGGAAGCAGACGAAACAGCAATGGACCAAGAAGAGGTGCTGATGTAAGAGTTAATGTAAGAATTACATTTGACG
AGTCAGTAAGGGGAACAACCAAGAAGATAGATGTTACATTAAAGGATGAGTGCTCAAGCTGTCACGGTACAGGAGCTAAG
CCTGGTACATCACCAGAGACCTGTAGCAAATGTGGTGGTCGTGGACAGGTGACTTTCACACAGCAGTCATTCCTTGGAAT
GGTAAGAAGCCAGCAGCCATGTCCTGACTGTCATGGAACTGGTAAGATAATTAAGGAGAAGTGTCCGGATTGTTACGGAA
CAGGCTATATAAGCAGCAAGAAGACTATCGAAGTCAATATCCCAGCAGGTATCGATAATGGTCAGTGCGTACGTATACAG
GGCAAAGGTGAGCCGGGAGTTAATGGCGGACCAAGAGGTGACCTCTTAGTTGCTGTTATTATCTCAGCAAGCACAGAATT
TGAAAGAGACGGATACAATATATTCTCTAATGTTGTAATAAGCTATCCAACAGCGGTACTTGGCGGTGAAATCAAGGTTA
AGACTGTTGATGGAGAAGTATTGTACGAAGTTAAGCCGGGAACAGCATCAGGTACAAGAGTAAGACTTAAAGGCAAAGGT
ATGCCAAGTGTAAGAAATGCAGCACAGAGAGGCGATCATTATATCACTTTAATAGTTGATATTCCTACAAAGCTTAATCA
GGAGCAGAAGGACGCACTTATGGCATATGAAAAGGCGCTTACAGGCAATGAAAGACACGGTAAGAAGAAAGGTCTTTTCG
GCAAATAA

Upstream 100 bases:

>100_bases
AAGAGGTTTAATTGTCAGCAATAACTGACTGGAATAAGGACTGCATGGGGTGTAAACTCCGTGCAGTTTCTGTTGATTAA
ATAAGAAAGAGGAAGCAATC

Downstream 100 bases:

>100_bases
ATACTATAGCTTACATATGTAATGTAAGTTTACACTCACCCCACAATGTGGTAAAATCCTACATTGTGGGGTATTATATT
TATATGTATAATTCCTTATT

Product: molecular chaperone DnaJ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 375; Mature: 374

Protein sequence:

>375_residues
MADKRDYYEVLGVPKDADDAAIKKAYRQLAKKYHPDMNPGDKEAEIKFKEASEAYAVLSDAEKRRQYDQFGHAAFEGGAG
GAGAGGFDFDFGDMGDIFGDLFGGMFGGGGSRRNSNGPRRGADVRVNVRITFDESVRGTTKKIDVTLKDECSSCHGTGAK
PGTSPETCSKCGGRGQVTFTQQSFLGMVRSQQPCPDCHGTGKIIKEKCPDCYGTGYISSKKTIEVNIPAGIDNGQCVRIQ
GKGEPGVNGGPRGDLLVAVIISASTEFERDGYNIFSNVVISYPTAVLGGEIKVKTVDGEVLYEVKPGTASGTRVRLKGKG
MPSVRNAAQRGDHYITLIVDIPTKLNQEQKDALMAYEKALTGNERHGKKKGLFGK

Sequences:

>Translated_375_residues
MADKRDYYEVLGVPKDADDAAIKKAYRQLAKKYHPDMNPGDKEAEIKFKEASEAYAVLSDAEKRRQYDQFGHAAFEGGAG
GAGAGGFDFDFGDMGDIFGDLFGGMFGGGGSRRNSNGPRRGADVRVNVRITFDESVRGTTKKIDVTLKDECSSCHGTGAK
PGTSPETCSKCGGRGQVTFTQQSFLGMVRSQQPCPDCHGTGKIIKEKCPDCYGTGYISSKKTIEVNIPAGIDNGQCVRIQ
GKGEPGVNGGPRGDLLVAVIISASTEFERDGYNIFSNVVISYPTAVLGGEIKVKTVDGEVLYEVKPGTASGTRVRLKGKG
MPSVRNAAQRGDHYITLIVDIPTKLNQEQKDALMAYEKALTGNERHGKKKGLFGK
>Mature_374_residues
ADKRDYYEVLGVPKDADDAAIKKAYRQLAKKYHPDMNPGDKEAEIKFKEASEAYAVLSDAEKRRQYDQFGHAAFEGGAGG
AGAGGFDFDFGDMGDIFGDLFGGMFGGGGSRRNSNGPRRGADVRVNVRITFDESVRGTTKKIDVTLKDECSSCHGTGAKP
GTSPETCSKCGGRGQVTFTQQSFLGMVRSQQPCPDCHGTGKIIKEKCPDCYGTGYISSKKTIEVNIPAGIDNGQCVRIQG
KGEPGVNGGPRGDLLVAVIISASTEFERDGYNIFSNVVISYPTAVLGGEIKVKTVDGEVLYEVKPGTASGTRVRLKGKGM
PSVRNAAQRGDHYITLIVDIPTKLNQEQKDALMAYEKALTGNERHGKKKGLFGK

Specific function: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion. Unfolded proteins bind initially to dnaJ; upon

COG id: COG0484

COG function: function code O; DnaJ-class molecular chaperone with C-terminal Zn finger domain

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 J domain

Homologues:

Organism=Homo sapiens, GI205360838, Length=359, Percent_Identity=36.2116991643454, Blast_Score=218, Evalue=6e-57,
Organism=Homo sapiens, GI205360840, Length=359, Percent_Identity=36.2116991643454, Blast_Score=218, Evalue=9e-57,
Organism=Homo sapiens, GI194328760, Length=350, Percent_Identity=34.2857142857143, Blast_Score=170, Evalue=3e-42,
Organism=Homo sapiens, GI194328758, Length=350, Percent_Identity=34.2857142857143, Blast_Score=169, Evalue=3e-42,
Organism=Homo sapiens, GI5031741, Length=363, Percent_Identity=34.7107438016529, Blast_Score=162, Evalue=6e-40,
Organism=Homo sapiens, GI4504511, Length=350, Percent_Identity=34, Blast_Score=158, Evalue=8e-39,
Organism=Homo sapiens, GI7706495, Length=353, Percent_Identity=31.1614730878187, Blast_Score=151, Evalue=8e-37,
Organism=Homo sapiens, GI194328762, Length=314, Percent_Identity=31.2101910828025, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI56549115, Length=404, Percent_Identity=25.7425742574257, Blast_Score=112, Evalue=8e-25,
Organism=Homo sapiens, GI201862518, Length=404, Percent_Identity=25.7425742574257, Blast_Score=112, Evalue=8e-25,
Organism=Homo sapiens, GI47777312, Length=104, Percent_Identity=53.8461538461538, Blast_Score=102, Evalue=8e-22,
Organism=Homo sapiens, GI9558755, Length=117, Percent_Identity=46.1538461538462, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI5453690, Length=375, Percent_Identity=28, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI194306642, Length=123, Percent_Identity=50.4065040650407, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI194306640, Length=123, Percent_Identity=50.4065040650407, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI27151736, Length=105, Percent_Identity=46.6666666666667, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI88501736, Length=105, Percent_Identity=46.6666666666667, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI23503241, Length=105, Percent_Identity=49.5238095238095, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI72534740, Length=108, Percent_Identity=50.9259259259259, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI17388799, Length=104, Percent_Identity=52.8846153846154, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI4885495, Length=104, Percent_Identity=52.8846153846154, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI201862587, Length=192, Percent_Identity=33.3333333333333, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI6631085, Length=185, Percent_Identity=37.2972972972973, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI21553335, Length=99, Percent_Identity=47.4747474747475, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI22749377, Length=117, Percent_Identity=42.7350427350427, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI39204547, Length=162, Percent_Identity=33.3333333333333, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI45504382, Length=80, Percent_Identity=50, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI29126218, Length=64, Percent_Identity=53.125, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI24308127, Length=94, Percent_Identity=37.2340425531915, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI56687498, Length=68, Percent_Identity=54.4117647058823, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1786197, Length=373, Percent_Identity=47.9892761394102, Blast_Score=332, Evalue=2e-92,
Organism=Escherichia coli, GI1787235, Length=369, Percent_Identity=29.810298102981, Blast_Score=152, Evalue=5e-38,
Organism=Caenorhabditis elegans, GI17553096, Length=375, Percent_Identity=36.8, Blast_Score=208, Evalue=5e-54,
Organism=Caenorhabditis elegans, GI17553098, Length=375, Percent_Identity=36.8, Blast_Score=207, Evalue=5e-54,
Organism=Caenorhabditis elegans, GI17507263, Length=351, Percent_Identity=33.9031339031339, Blast_Score=149, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI212645553, Length=353, Percent_Identity=33.1444759206799, Blast_Score=143, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17554644, Length=109, Percent_Identity=47.7064220183486, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17534355, Length=182, Percent_Identity=39.5604395604396, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17563890, Length=239, Percent_Identity=28.0334728033473, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI115532378, Length=96, Percent_Identity=44.7916666666667, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17538236, Length=127, Percent_Identity=43.3070866141732, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17568643, Length=65, Percent_Identity=56.9230769230769, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI86563276, Length=112, Percent_Identity=39.2857142857143, Blast_Score=65, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6324265, Length=327, Percent_Identity=38.8379204892966, Blast_Score=187, Evalue=2e-48,
Organism=Saccharomyces cerevisiae, GI6323870, Length=351, Percent_Identity=35.8974358974359, Blast_Score=162, Evalue=7e-41,
Organism=Saccharomyces cerevisiae, GI6323119, Length=387, Percent_Identity=31.0077519379845, Blast_Score=144, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6321094, Length=386, Percent_Identity=32.1243523316062, Blast_Score=134, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6324252, Length=428, Percent_Identity=26.8691588785047, Blast_Score=119, Evalue=9e-28,
Organism=Saccharomyces cerevisiae, GI6323813, Length=132, Percent_Identity=40.1515151515151, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6320888, Length=104, Percent_Identity=40.3846153846154, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6322194, Length=150, Percent_Identity=34.6666666666667, Blast_Score=70, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6324321, Length=74, Percent_Identity=47.2972972972973, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6324103, Length=63, Percent_Identity=52.3809523809524, Blast_Score=63, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6322388, Length=70, Percent_Identity=47.1428571428571, Blast_Score=63, Evalue=8e-11,
Organism=Drosophila melanogaster, GI45552813, Length=372, Percent_Identity=36.5591397849462, Blast_Score=199, Evalue=2e-51,
Organism=Drosophila melanogaster, GI45549272, Length=372, Percent_Identity=36.5591397849462, Blast_Score=199, Evalue=2e-51,
Organism=Drosophila melanogaster, GI45552811, Length=372, Percent_Identity=36.5591397849462, Blast_Score=199, Evalue=2e-51,
Organism=Drosophila melanogaster, GI20129487, Length=349, Percent_Identity=34.3839541547278, Blast_Score=155, Evalue=4e-38,
Organism=Drosophila melanogaster, GI24584014, Length=349, Percent_Identity=34.3839541547278, Blast_Score=155, Evalue=4e-38,
Organism=Drosophila melanogaster, GI24646562, Length=352, Percent_Identity=34.0909090909091, Blast_Score=150, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24646560, Length=352, Percent_Identity=34.0909090909091, Blast_Score=150, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24646558, Length=352, Percent_Identity=34.0909090909091, Blast_Score=150, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24646556, Length=352, Percent_Identity=34.0909090909091, Blast_Score=150, Evalue=1e-36,
Organism=Drosophila melanogaster, GI21357547, Length=352, Percent_Identity=34.0909090909091, Blast_Score=150, Evalue=1e-36,
Organism=Drosophila melanogaster, GI19920464, Length=353, Percent_Identity=31.1614730878187, Blast_Score=148, Evalue=5e-36,
Organism=Drosophila melanogaster, GI28574949, Length=366, Percent_Identity=28.6885245901639, Blast_Score=137, Evalue=1e-32,
Organism=Drosophila melanogaster, GI85726398, Length=376, Percent_Identity=28.7234042553192, Blast_Score=115, Evalue=5e-26,
Organism=Drosophila melanogaster, GI24658562, Length=374, Percent_Identity=25.668449197861, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24658555, Length=374, Percent_Identity=25.668449197861, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24654066, Length=119, Percent_Identity=41.1764705882353, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24654070, Length=119, Percent_Identity=41.1764705882353, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24654068, Length=119, Percent_Identity=41.1764705882353, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24654072, Length=119, Percent_Identity=41.1764705882353, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI161077138, Length=64, Percent_Identity=59.375, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI18858081, Length=352, Percent_Identity=25.5681818181818, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI17648033, Length=109, Percent_Identity=38.5321100917431, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24584630, Length=109, Percent_Identity=38.5321100917431, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI17737735, Length=64, Percent_Identity=54.6875, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI28574723, Length=64, Percent_Identity=54.6875, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24668523, Length=64, Percent_Identity=54.6875, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI21358273, Length=69, Percent_Identity=56.5217391304348, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DNAJ_EUBE2 (C4Z1J3)

Other databases:

- EMBL:   CP001104
- RefSeq:   YP_002930801.1
- ProteinModelPortal:   C4Z1J3
- GeneID:   7958214
- GenomeReviews:   CP001104_GR
- KEGG:   eel:EUBELI_01359
- OMA:   SHITIRI
- ProtClustDB:   CLSK2540951
- GO:   GO:0005737
- HAMAP:   MF_01152
- InterPro:   IPR012724
- InterPro:   IPR002939
- InterPro:   IPR001623
- InterPro:   IPR018253
- InterPro:   IPR008971
- InterPro:   IPR015609
- InterPro:   IPR003095
- InterPro:   IPR001305
- Gene3D:   G3DSA:1.10.287.110
- Gene3D:   G3DSA:2.10.230.10
- PANTHER:   PTHR11821
- PRINTS:   PR00625
- SMART:   SM00271
- TIGRFAMs:   TIGR02349

Pfam domain/function: PF00226 DnaJ; PF01556 DnaJ_C; PF00684 DnaJ_CXXCXGXG; SSF46565 DnaJ_N; SSF49493 HSP40_DnaJ_pep; SSF57938 HSP_DnaJ_cys-rich

EC number: NA

Molecular weight: Translated: 40234; Mature: 40103

Theoretical pI: Translated: 8.59; Mature: 8.59

Prosite motif: PS00636 DNAJ_1; PS50076 DNAJ_2; PS51188 ZF_CR; PS00637 DNAJ_CXXCXGXG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADKRDYYEVLGVPKDADDAAIKKAYRQLAKKYHPDMNPGDKEAEIKFKEASEAYAVLSD
CCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCHHHHHHHH
AEKRRQYDQFGHAAFEGGAGGAGAGGFDFDFGDMGDIFGDLFGGMFGGGGSRRNSNGPRR
HHHHHHHHHHCCHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCC
GADVRVNVRITFDESVRGTTKKIDVTLKDECSSCHGTGAKPGTSPETCSKCGGRGQVTFT
CCEEEEEEEEEECCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHCCCCCEEEEE
QQSFLGMVRSQQPCPDCHGTGKIIKEKCPDCYGTGYISSKKTIEVNIPAGIDNGQCVRIQ
HHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCCCCCEECCCCEEEEECCCCCCCCCEEEEE
GKGEPGVNGGPRGDLLVAVIISASTEFERDGYNIFSNVVISYPTAVLGGEIKVKTVDGEV
CCCCCCCCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHCCHHHCCCEEEEEEECCEE
LYEVKPGTASGTRVRLKGKGMPSVRNAAQRGDHYITLIVDIPTKLNQEQKDALMAYEKAL
EEEECCCCCCCCEEEEECCCCCHHHHHHHCCCEEEEEEEECCCCCCHHHHHHHHHHHHHH
TGNERHGKKKGLFGK
CCCCCCCCCCCCCCC
>Mature Secondary Structure 
ADKRDYYEVLGVPKDADDAAIKKAYRQLAKKYHPDMNPGDKEAEIKFKEASEAYAVLSD
CCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCHHHHHHHH
AEKRRQYDQFGHAAFEGGAGGAGAGGFDFDFGDMGDIFGDLFGGMFGGGGSRRNSNGPRR
HHHHHHHHHHCCHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCC
GADVRVNVRITFDESVRGTTKKIDVTLKDECSSCHGTGAKPGTSPETCSKCGGRGQVTFT
CCEEEEEEEEEECCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHCCCCCEEEEE
QQSFLGMVRSQQPCPDCHGTGKIIKEKCPDCYGTGYISSKKTIEVNIPAGIDNGQCVRIQ
HHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCCCCCEECCCCEEEEECCCCCCCCCEEEEE
GKGEPGVNGGPRGDLLVAVIISASTEFERDGYNIFSNVVISYPTAVLGGEIKVKTVDGEV
CCCCCCCCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHCCHHHCCCEEEEEEECCEE
LYEVKPGTASGTRVRLKGKGMPSVRNAAQRGDHYITLIVDIPTKLNQEQKDALMAYEKAL
EEEECCCCCCCCEEEEECCCCCHHHHHHHCCCEEEEEEEECCCCCCHHHHHHHHHHHHHH
TGNERHGKKKGLFGK
CCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA