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The map label for this gene is era [H]

Identifier: 238917282

GI number: 238917282

Start: 1393388

End: 1394356

Strand: Reverse

Name: era [H]

Synonym: EUBELI_01357

Alternate gene names: 238917282

Gene position: 1394356-1393388 (Counterclockwise)

Preceding gene: 238917283

Following gene: 238917281

Centisome position: 65.03

GC content: 40.66

Gene sequence:

>969_bases
ATGAATTTAGATGAGATGCTTGCAGCCAGCGGAATTACCGGGGGCGCTAAGGCAGAGAACACAAGAACTAAGACAGGCTT
TGTAACATTTATAGGAAGACCTAATGTTGGTAAGTCAACACTTATGAACCAGATAATCGGACAGAAGATTGCGATTACTT
CTAACAAGCCTCAGACTACAAGAAACAGAATACAGACTGTATACACTGATGAGCGTGGACAGATTGTTTTCGTTGATACT
CCGGGTATCCACAAGGCTAAGAACAAGCTTGGTGAATACATGGTTGGTGCGGCAGAGAAGACAATCAGCGAGGTTGACCT
TATATGCTGGCTAGTTGAGCCTACAACACATCTTGGAGCTGCCGAGGAGCATATCGTAGAGAAGCTTAAAGAGTGTAAGA
CTCCTATAGTTCTTGTGATCAATAAGACTGACACAATTAAGAAAGAGGAGATTCTTCCGGTTATTGACTGCTACAGAAAG
GAACTTGATTTTGTTGATATTGTTCCTGTATGTGCAAGAAACGGCAATAATGTTGATGACCTGCTTGATGTTATATTCTT
ACATCTTGATTATGGTCCGATGTACTATGATGAAGATACAGTAACAGACCAGCCAATGAAGCAGATTGTTGCAGAACTTA
TAAGAGAGAAGGCACTTCATGCATTAAATGACGAGATTCCACACGGAATTGCGGTTGTTATTGACAGCTTCAAGGAAAGA
AGAAATGCAAGAGGTCCTATAACAGATATCGACGCTACTATCATATGCGAAAGAGATTCCCACAAAGGAATTATTATTGG
CAAGGGCGGCGAAATGCTTAAGAAAATCGGAACTAATGCAAGATACGAGATTGAGAAGCAGCTTGACATGAAGGTTAATC
TTAAGCTCTGGGTAAAAGTTAAGAAGGAATGGCGCGACAGTGATATTCTTCTTAAGAACTTCGGATATGACAAGAAGAAG
GACAAATAA

Upstream 100 bases:

>100_bases
TGCGTTGTGGGAAGCAGCAAGGAAATCAATAAAGAGAGTGAACTTTTTGATAAGATACAGCCACTTATCAAGGTACAGGG
ATAATAGAAAGGAAGAATGT

Downstream 100 bases:

>100_bases
TATACATGACAGGAGGGTGCGATGGCGGAGGTTACTACTGTTACAGGCATGATACTTTCCGCCATGCCTGTCGGTGAATA
TGACAGAAGACTGGTTATAC

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MNLDEMLAASGITGGAKAENTRTKTGFVTFIGRPNVGKSTLMNQIIGQKIAITSNKPQTTRNRIQTVYTDERGQIVFVDT
PGIHKAKNKLGEYMVGAAEKTISEVDLICWLVEPTTHLGAAEEHIVEKLKECKTPIVLVINKTDTIKKEEILPVIDCYRK
ELDFVDIVPVCARNGNNVDDLLDVIFLHLDYGPMYYDEDTVTDQPMKQIVAELIREKALHALNDEIPHGIAVVIDSFKER
RNARGPITDIDATIICERDSHKGIIIGKGGEMLKKIGTNARYEIEKQLDMKVNLKLWVKVKKEWRDSDILLKNFGYDKKK
DK

Sequences:

>Translated_322_residues
MNLDEMLAASGITGGAKAENTRTKTGFVTFIGRPNVGKSTLMNQIIGQKIAITSNKPQTTRNRIQTVYTDERGQIVFVDT
PGIHKAKNKLGEYMVGAAEKTISEVDLICWLVEPTTHLGAAEEHIVEKLKECKTPIVLVINKTDTIKKEEILPVIDCYRK
ELDFVDIVPVCARNGNNVDDLLDVIFLHLDYGPMYYDEDTVTDQPMKQIVAELIREKALHALNDEIPHGIAVVIDSFKER
RNARGPITDIDATIICERDSHKGIIIGKGGEMLKKIGTNARYEIEKQLDMKVNLKLWVKVKKEWRDSDILLKNFGYDKKK
DK
>Mature_322_residues
MNLDEMLAASGITGGAKAENTRTKTGFVTFIGRPNVGKSTLMNQIIGQKIAITSNKPQTTRNRIQTVYTDERGQIVFVDT
PGIHKAKNKLGEYMVGAAEKTISEVDLICWLVEPTTHLGAAEEHIVEKLKECKTPIVLVINKTDTIKKEEILPVIDCYRK
ELDFVDIVPVCARNGNNVDDLLDVIFLHLDYGPMYYDEDTVTDQPMKQIVAELIREKALHALNDEIPHGIAVVIDSFKER
RNARGPITDIDATIICERDSHKGIIIGKGGEMLKKIGTNARYEIEKQLDMKVNLKLWVKVKKEWRDSDILLKNFGYDKKK
DK

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism [H]

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain [H]

Homologues:

Organism=Homo sapiens, GI24307899, Length=348, Percent_Identity=24.1379310344828, Blast_Score=82, Evalue=9e-16,
Organism=Escherichia coli, GI1788919, Length=297, Percent_Identity=38.7205387205387, Blast_Score=225, Evalue=4e-60,
Organism=Escherichia coli, GI87082120, Length=160, Percent_Identity=31.875, Blast_Score=83, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6323665, Length=203, Percent_Identity=25.1231527093596, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24646434, Length=305, Percent_Identity=23.2786885245902, Blast_Score=81, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005662
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 36289; Mature: 36289

Theoretical pI: Translated: 7.17; Mature: 7.17

Prosite motif: PS50823 KH_TYPE_2 ; PS00307 LECTIN_LEGUME_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLDEMLAASGITGGAKAENTRTKTGFVTFIGRPNVGKSTLMNQIIGQKIAITSNKPQTT
CCHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCEEEEECCCCHHH
RNRIQTVYTDERGQIVFVDTPGIHKAKNKLGEYMVGAAEKTISEVDLICWLVEPTTHLGA
HHHEEEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCHHCCC
AEEHIVEKLKECKTPIVLVINKTDTIKKEEILPVIDCYRKELDFVDIVPVCARNGNNVDD
HHHHHHHHHHHCCCCEEEEECCCCCCCHHHCCHHHHHHHHHCCCEEEHHHHCCCCCCHHH
LLDVIFLHLDYGPMYYDEDTVTDQPMKQIVAELIREKALHALNDEIPHGIAVVIDSFKER
HHHHHHHHCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
RNARGPITDIDATIICERDSHKGIIIGKGGEMLKKIGTNARYEIEKQLDMKVNLKLWVKV
HCCCCCCCCCCEEEEEECCCCCEEEEECCHHHHHHHCCCCEEEEEECCCEEEEEEEEEEE
KKEWRDSDILLKNFGYDKKKDK
EHHCCCCCEEHHHCCCCCCCCC
>Mature Secondary Structure
MNLDEMLAASGITGGAKAENTRTKTGFVTFIGRPNVGKSTLMNQIIGQKIAITSNKPQTT
CCHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCEEEEECCCCHHH
RNRIQTVYTDERGQIVFVDTPGIHKAKNKLGEYMVGAAEKTISEVDLICWLVEPTTHLGA
HHHEEEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCHHCCC
AEEHIVEKLKECKTPIVLVINKTDTIKKEEILPVIDCYRKELDFVDIVPVCARNGNNVDD
HHHHHHHHHHHCCCCEEEEECCCCCCCHHHCCHHHHHHHHHCCCEEEHHHHCCCCCCHHH
LLDVIFLHLDYGPMYYDEDTVTDQPMKQIVAELIREKALHALNDEIPHGIAVVIDSFKER
HHHHHHHHCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
RNARGPITDIDATIICERDSHKGIIIGKGGEMLKKIGTNARYEIEKQLDMKVNLKLWVKV
HCCCCCCCCCCEEEEEECCCCCEEEEECCHHHHHHHCCCCEEEEEECCCEEEEEEEEEEE
KKEWRDSDILLKNFGYDKKKDK
EHHCCCCCEEHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA