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The map label for this gene is trpD

Identifier: 238917204

GI number: 238917204

Start: 1315510

End: 1316517

Strand: Reverse

Name: trpD

Synonym: EUBELI_01277

Alternate gene names: 238917204

Gene position: 1316517-1315510 (Counterclockwise)

Preceding gene: 238917205

Following gene: 238917202

Centisome position: 61.4

GC content: 40.58

Gene sequence:

>1008_bases
ATGATTAAAGAAGCTATTGCAAAGCTGGTTAAGAAAGAAGATTTAACTGCTGGGCAGATGAATGATGTAATGGAAGAGAT
TATGACAGGAGAAGCCACTGATGCACAGAAGGCAGCATTTCTTACAGCTCTGGCAGCAAAGGGAGAGACTATTGACGAGA
TTACAGCAGCAGCAAGAGTTTTAAGAGCACACTGTGAGAAGTTCTTAAATGATATGGATGTTCTTGAAATCGTTGGAACA
GGTGGAGATGGTTCTAATTCAATCAATATATCAACCTTAGCTTCTATCATAGTATCAGCAGCTGGAATACCGGTTGCTAA
GCATGGTAACAGAGCAGCTTCAAGCAAATGTGGTACAGCAGACTGTTTAGAGGCTCTTGGCGTTAAGATAGATGCAGCTC
CTGCAAGGATGGCACAGATTCTTAAGGATATTAATATATGTTTTCTTTTTGCACAGAAATATCATCCGGCTATGAGATTT
GTTGGAGGTGTGAGAAAGGAAATTGGAATCCGTACATTATTCAATATACTTGGACCTCTGGCCAATCCGGCAGGGGCATC
TATGCAGCTTTTTGGTGTATATAGTGAGGAGCTTGTTGAGCCGCTTGCACATGTATTACATAATTTAGGCTGCAAAAGAG
CTATGACAATATACGGAATGGACAGCATAGATGAGATATCTTTAAGTGCTGATACAAAGGTATGCGAGTTCAAAGGTGAT
GAGTTCAAATCATATACTATAAAGCCGGAGGATTTTGGATTTACAAGATGCAAGAAGGAAGATCTTGCTGGTGGTGAGCC
GGCAGTTAATGCCAGGATTGCAAGAGATATTCTTGAAGGTGCAGAAGGACCTAAGACAGATGTGGTACTTCTTAATGCCG
GAGCTGCCATATATCTTGCTTCAGATGGTATTACAATGAAGGAAGGTATTGAGAAAGCAAGAGAGATTATTAAGAGCGGA
GCAGCTAAGAAGCAGCTTGAAAGATTTATAGAAGAGACTAATAAGTAA

Upstream 100 bases:

>100_bases
AGACAGATAACCTTTGTAAGCTGTTATGGATTGACAGCACGGCGTTATAGTAATACACTAAAGCTATCATTTAGATATGT
TTATGGGAGGCTAAGGTAAT

Downstream 100 bases:

>100_bases
TTAACAGAATATGTGTTAGGTATAACAAAACCCCTGTCGCATTAGCGGCAGGGGTTAATTGTTATTATAATTATAAAAAA
TTAAGCGGCTTCTTTAACTC

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MIKEAIAKLVKKEDLTAGQMNDVMEEIMTGEATDAQKAAFLTALAAKGETIDEITAAARVLRAHCEKFLNDMDVLEIVGT
GGDGSNSINISTLASIIVSAAGIPVAKHGNRAASSKCGTADCLEALGVKIDAAPARMAQILKDINICFLFAQKYHPAMRF
VGGVRKEIGIRTLFNILGPLANPAGASMQLFGVYSEELVEPLAHVLHNLGCKRAMTIYGMDSIDEISLSADTKVCEFKGD
EFKSYTIKPEDFGFTRCKKEDLAGGEPAVNARIARDILEGAEGPKTDVVLLNAGAAIYLASDGITMKEGIEKAREIIKSG
AAKKQLERFIEETNK

Sequences:

>Translated_335_residues
MIKEAIAKLVKKEDLTAGQMNDVMEEIMTGEATDAQKAAFLTALAAKGETIDEITAAARVLRAHCEKFLNDMDVLEIVGT
GGDGSNSINISTLASIIVSAAGIPVAKHGNRAASSKCGTADCLEALGVKIDAAPARMAQILKDINICFLFAQKYHPAMRF
VGGVRKEIGIRTLFNILGPLANPAGASMQLFGVYSEELVEPLAHVLHNLGCKRAMTIYGMDSIDEISLSADTKVCEFKGD
EFKSYTIKPEDFGFTRCKKEDLAGGEPAVNARIARDILEGAEGPKTDVVLLNAGAAIYLASDGITMKEGIEKAREIIKSG
AAKKQLERFIEETNK
>Mature_335_residues
MIKEAIAKLVKKEDLTAGQMNDVMEEIMTGEATDAQKAAFLTALAAKGETIDEITAAARVLRAHCEKFLNDMDVLEIVGT
GGDGSNSINISTLASIIVSAAGIPVAKHGNRAASSKCGTADCLEALGVKIDAAPARMAQILKDINICFLFAQKYHPAMRF
VGGVRKEIGIRTLFNILGPLANPAGASMQLFGVYSEELVEPLAHVLHNLGCKRAMTIYGMDSIDEISLSADTKVCEFKGD
EFKSYTIKPEDFGFTRCKKEDLAGGEPAVNARIARDILEGAEGPKTDVVLLNAGAAIYLASDGITMKEGIEKAREIIKSG
AAKKQLERFIEETNK

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family

Homologues:

Organism=Escherichia coli, GI1787517, Length=280, Percent_Identity=42.5, Blast_Score=210, Evalue=8e-56,
Organism=Saccharomyces cerevisiae, GI6320561, Length=278, Percent_Identity=33.4532374100719, Blast_Score=137, Evalue=2e-33,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPD_EUBE2 (C4Z111)

Other databases:

- EMBL:   CP001104
- RefSeq:   YP_002930721.1
- GeneID:   7956623
- GenomeReviews:   CP001104_GR
- KEGG:   eel:EUBELI_01277
- OMA:   LGVYSPE
- HAMAP:   MF_00211
- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- Gene3D:   G3DSA:1.20.970.10
- Gene3D:   G3DSA:3.40.1030.10
- TIGRFAMs:   TIGR01245

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; SSF47648 Glyco_trans_3; SSF52418 Glyco_trans_3

EC number: =2.4.2.18

Molecular weight: Translated: 35841; Mature: 35841

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKEAIAKLVKKEDLTAGQMNDVMEEIMTGEATDAQKAAFLTALAAKGETIDEITAAARV
CCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHH
LRAHCEKFLNDMDVLEIVGTGGDGSNSINISTLASIIVSAAGIPVAKHGNRAASSKCGTA
HHHHHHHHHCCCCCHHEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHCCCCCHH
DCLEALGVKIDAAPARMAQILKDINICFLFAQKYHPAMRFVGGVRKEIGIRTLFNILGPL
HHHHHHCCCCCCCHHHHHHHHHHHHHHEEHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHC
ANPAGASMQLFGVYSEELVEPLAHVLHNLGCKRAMTIYGMDSIDEISLSADTKVCEFKGD
CCCCCCCEEEEECHHHHHHHHHHHHHHHCCHHHEEEEECCCCCHHCCCCCCCCEEECCCC
EFKSYTIKPEDFGFTRCKKEDLAGGEPAVNARIARDILEGAEGPKTDVVLLNAGAAIYLA
CCCEEECCCCCCCCHHCCHHHCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEECCEEEEEE
SDGITMKEGIEKAREIIKSGAAKKQLERFIEETNK
CCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MIKEAIAKLVKKEDLTAGQMNDVMEEIMTGEATDAQKAAFLTALAAKGETIDEITAAARV
CCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHH
LRAHCEKFLNDMDVLEIVGTGGDGSNSINISTLASIIVSAAGIPVAKHGNRAASSKCGTA
HHHHHHHHHCCCCCHHEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHCCCCCHH
DCLEALGVKIDAAPARMAQILKDINICFLFAQKYHPAMRFVGGVRKEIGIRTLFNILGPL
HHHHHHCCCCCCCHHHHHHHHHHHHHHEEHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHC
ANPAGASMQLFGVYSEELVEPLAHVLHNLGCKRAMTIYGMDSIDEISLSADTKVCEFKGD
CCCCCCCEEEEECHHHHHHHHHHHHHHHCCHHHEEEEECCCCCHHCCCCCCCCEEECCCC
EFKSYTIKPEDFGFTRCKKEDLAGGEPAVNARIARDILEGAEGPKTDVVLLNAGAAIYLA
CCCEEECCCCCCCCHHCCHHHCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEECCEEEEEE
SDGITMKEGIEKAREIIKSGAAKKQLERFIEETNK
CCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA