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The map label for this gene is mepA [H]

Identifier: 238917182

GI number: 238917182

Start: 1284040

End: 1285335

Strand: Reverse

Name: mepA [H]

Synonym: EUBELI_01255

Alternate gene names: 238917182

Gene position: 1285335-1284040 (Counterclockwise)

Preceding gene: 238917183

Following gene: 238917181

Centisome position: 59.95

GC content: 38.81

Gene sequence:

>1296_bases
ATGAGCAAGGAGGAAAACAGAAAGAATTTTTCTAAATATGTATCGCAGAATATTCTCGGAATGATAGGGTTTTCATGCTA
CGTTCTTGCTGACTCGTATTTTATATCTATAGCAAAGGGAGCAGACGGACTTACAGCATTAAATCTTGTTATGCCATTAT
ATAGTATAATATTCTCAATTGGTGAGATGATTGGTGTTGGTTCAGCTATAAGATATGCAATCAGTAAGATTAAAAAAGAT
GCAGATGCAGATGATTATTTCTGGAATGCATTAATATGGTGTATATTGTCAAGTATGATATTCGTTTTTGCCGGAATATT
CTTTTCGGCAGATATCATGCGTGTTCTAGGAGCTGATGAACATATTGTAGCAGTTGGGAATAATTACACTAAGATATTCA
TGTGTTTTGCACCGATGTTTATGTGTAATTATGTGACTAATGCATTTGTAAGAAATGACGGAGCACCGGGAATTGCTATG
AGTGCAACACTTTTTAGCAGTCTGTTTAATATAGTATTTGACTATATTCTCATGTTCCCGATGAATCTGGGAATGGAAGG
TGCAGCACTGGCAACAGCTTTGTCGCCGATTATCGGAATGGGAATATGCAGCATACATTTCTTCTCTAAGAAAAGCAGTG
TCAGGCTTGTTGTGTGTAAGCCTTCAGTCAGAAAACTTGTGGCAGGGTGCCAGCTTGGTATATCGGCATTTGTTGGAGAG
ATGTCATCAGCTGTTATTACACTTGTTTTTAATTTCGTAATTCTTAAGCTGGCTGGTAATGTCGGAGTAGCTGCATACGG
AGTTGTGGCTAATATTGCAATTGTCACAACTGCGGTATTTAATGGTGTTGCACAGGGAAGTCAGCCACTTATAAGCAGTT
GTTTCGGCAGGGGAGACAAGGATGGATGTAAACAGTTAAAACGAATGGGATATACAACAGCATTGGTACTTGCAGCGGTT
ATGTATAGTATATTGTTTATATTTGCAGGACAGTTTGTCGCAGTGTTTAACAGTGAAGGTTCAGAAATGTTAAGGCTTTA
CGCAACAGAAGGCGTTAAGTTATATTTTATTGGAATATTCTTTGCGGGAATTAATATTGTAGGTGGCGGTGCATTCAGTG
CAACAGAGGATGCGTTTAAAGCGGCAGTTGTTTCTGTGGCAAGAGGATTTGTGCTGATTTTAGGTGCAGTTTTTGTAATG
TCAGCACTTTTTGGAATGACAGGAGTATGGCTTGCGTATGCCGTTGCTGAGGGAATAACAACATTTATAATGCTTGTAAT
GGTGCTGAGAGTGTGA

Upstream 100 bases:

>100_bases
CATGTAATTGCTTTGCGCTAAGAGATATGATAGTGTGTAAAATGCGGCTCCCAACGGGAGCCGTTTTTGTAACTTATATT
ATTTAATTAAGGAGATTTCG

Downstream 100 bases:

>100_bases
TAGAATATTTGCGGACAAAATTATCCCAGAGATTGGGAAAATATGAAAGGAGTCTATATAATTATGAGCAATATTGCAGA
CAAATTTGAAGAACTTGGAG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 431; Mature: 430

Protein sequence:

>431_residues
MSKEENRKNFSKYVSQNILGMIGFSCYVLADSYFISIAKGADGLTALNLVMPLYSIIFSIGEMIGVGSAIRYAISKIKKD
ADADDYFWNALIWCILSSMIFVFAGIFFSADIMRVLGADEHIVAVGNNYTKIFMCFAPMFMCNYVTNAFVRNDGAPGIAM
SATLFSSLFNIVFDYILMFPMNLGMEGAALATALSPIIGMGICSIHFFSKKSSVRLVVCKPSVRKLVAGCQLGISAFVGE
MSSAVITLVFNFVILKLAGNVGVAAYGVVANIAIVTTAVFNGVAQGSQPLISSCFGRGDKDGCKQLKRMGYTTALVLAAV
MYSILFIFAGQFVAVFNSEGSEMLRLYATEGVKLYFIGIFFAGINIVGGGAFSATEDAFKAAVVSVARGFVLILGAVFVM
SALFGMTGVWLAYAVAEGITTFIMLVMVLRV

Sequences:

>Translated_431_residues
MSKEENRKNFSKYVSQNILGMIGFSCYVLADSYFISIAKGADGLTALNLVMPLYSIIFSIGEMIGVGSAIRYAISKIKKD
ADADDYFWNALIWCILSSMIFVFAGIFFSADIMRVLGADEHIVAVGNNYTKIFMCFAPMFMCNYVTNAFVRNDGAPGIAM
SATLFSSLFNIVFDYILMFPMNLGMEGAALATALSPIIGMGICSIHFFSKKSSVRLVVCKPSVRKLVAGCQLGISAFVGE
MSSAVITLVFNFVILKLAGNVGVAAYGVVANIAIVTTAVFNGVAQGSQPLISSCFGRGDKDGCKQLKRMGYTTALVLAAV
MYSILFIFAGQFVAVFNSEGSEMLRLYATEGVKLYFIGIFFAGINIVGGGAFSATEDAFKAAVVSVARGFVLILGAVFVM
SALFGMTGVWLAYAVAEGITTFIMLVMVLRV
>Mature_430_residues
SKEENRKNFSKYVSQNILGMIGFSCYVLADSYFISIAKGADGLTALNLVMPLYSIIFSIGEMIGVGSAIRYAISKIKKDA
DADDYFWNALIWCILSSMIFVFAGIFFSADIMRVLGADEHIVAVGNNYTKIFMCFAPMFMCNYVTNAFVRNDGAPGIAMS
ATLFSSLFNIVFDYILMFPMNLGMEGAALATALSPIIGMGICSIHFFSKKSSVRLVVCKPSVRKLVAGCQLGISAFVGEM
SSAVITLVFNFVILKLAGNVGVAAYGVVANIAIVTTAVFNGVAQGSQPLISSCFGRGDKDGCKQLKRMGYTTALVLAAVM
YSILFIFAGQFVAVFNSEGSEMLRLYATEGVKLYFIGIFFAGINIVGGGAFSATEDAFKAAVVSVARGFVLILGAVFVMS
ALFGMTGVWLAYAVAEGITTFIMLVMVLRV

Specific function: Multidrug resistance efflux protein [H]

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528
- InterPro:   IPR015522 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 46222; Mature: 46091

Theoretical pI: Translated: 8.44; Mature: 8.44

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
7.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKEENRKNFSKYVSQNILGMIGFSCYVLADSYFISIAKGADGLTALNLVMPLYSIIFSI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHH
GEMIGVGSAIRYAISKIKKDADADDYFWNALIWCILSSMIFVFAGIFFSADIMRVLGADE
HHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
HIVAVGNNYTKIFMCFAPMFMCNYVTNAFVRNDGAPGIAMSATLFSSLFNIVFDYILMFP
EEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
MNLGMEGAALATALSPIIGMGICSIHFFSKKSSVRLVVCKPSVRKLVAGCQLGISAFVGE
HCCCCCHHHHHHHHHHHHHHHHHHHEEECCCCCEEEEEECHHHHHHHHHHHHHHHHHHHH
MSSAVITLVFNFVILKLAGNVGVAAYGVVANIAIVTTAVFNGVAQGSQPLISSCFGRGDK
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCH
DGCKQLKRMGYTTALVLAAVMYSILFIFAGQFVAVFNSEGSEMLRLYATEGVKLYFIGIF
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHCCCCCHHHHHHH
FAGINIVGGGAFSATEDAFKAAVVSVARGFVLILGAVFVMSALFGMTGVWLAYAVAEGIT
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TFIMLVMVLRV
HHHHHHHHHHC
>Mature Secondary Structure 
SKEENRKNFSKYVSQNILGMIGFSCYVLADSYFISIAKGADGLTALNLVMPLYSIIFSI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHH
GEMIGVGSAIRYAISKIKKDADADDYFWNALIWCILSSMIFVFAGIFFSADIMRVLGADE
HHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
HIVAVGNNYTKIFMCFAPMFMCNYVTNAFVRNDGAPGIAMSATLFSSLFNIVFDYILMFP
EEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
MNLGMEGAALATALSPIIGMGICSIHFFSKKSSVRLVVCKPSVRKLVAGCQLGISAFVGE
HCCCCCHHHHHHHHHHHHHHHHHHHEEECCCCCEEEEEECHHHHHHHHHHHHHHHHHHHH
MSSAVITLVFNFVILKLAGNVGVAAYGVVANIAIVTTAVFNGVAQGSQPLISSCFGRGDK
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCH
DGCKQLKRMGYTTALVLAAVMYSILFIFAGQFVAVFNSEGSEMLRLYATEGVKLYFIGIF
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHCCCCCHHHHHHH
FAGINIVGGGAFSATEDAFKAAVVSVARGFVLILGAVFVMSALFGMTGVWLAYAVAEGIT
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TFIMLVMVLRV
HHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA