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The map label for this gene is dapL [H]

Identifier: 238917180

GI number: 238917180

Start: 1281998

End: 1283242

Strand: Direct

Name: dapL [H]

Synonym: EUBELI_01253

Alternate gene names: 238917180

Gene position: 1281998-1283242 (Clockwise)

Preceding gene: 238917168

Following gene: 238917186

Centisome position: 59.79

GC content: 39.2

Gene sequence:

>1245_bases
ATGCTAGTATCTTATTCGATAGGCTTGAAATTTTTCTATATTTCCGGTCTGAATAAAATGCATGCAGATACGCATTTAAA
GAAATGGAGTATACATATGAATATTGAATTTTCTAAAAGAGCTGACCGCTTTGGCAGCAACATTTTTAATATACTTAATG
AAAAGAAGAACGACCGACTTGCACAGGGAAAGCCGGTATATAACTTTACTGTAGGGACTCCTGATTTCAAGCCTGATGAA
TCTGTTATGAAGGTTGTTTCAGATGCAGCACTTGATCCTGAGAATTACAAATACTCACTTGGTGATACTGATGAGCTGCT
TGACGCCGTATGCAAATGGTACAAACGCCGTTACAACACTGTTATCACACCTGATGAAGTCACCTCTGTATTCGGAACTC
AGGAAGGTATGGCTCATATTGCCCTTGCTTTGTGCAATCCGGGAGATTTATGCTTAGTTCCTAATCCGGGATATCCTATA
TTCGAGATTGGACCATTCCTGTGTGATGCACAGATTGCTTATTACAATCTTCTTCCAGAGAATGATTATCTTATAGATTT
TGATTCTATTGATGAAGATACTGCAAAAAGAGCCAAAATGATGGTTGTATCTTATCCACTGAATCCTGTATGTGCTACTG
CACCTGATGAATTCTACGATAAACTCATCGCATTTGCAAAGAAATATAACATCATTATTATTCACGACAACGCATATTCT
GAGATTATATATGACGGACAGATTGGTGGCTCTTTCTTAAGCCACGAAGGTGCTATGGAAGTCGGAGTTGAATTCAACTC
TCTTTCTAAGACTTATAATCTTACTGGTCTGCGCCTTTCATTTCTTATCGGAAACCGTGAAATCGTAAGCAAATTCAAAA
CTGTCCGCTCACAATTTGACTATGGAACAAGTCTTATATACCAGAAAGCTGCTGTTGCTGCACTTAACGGTCCGCAGGAA
TATGTCGCTGACAACCGTGCTGAATATGAGTTAAGAAGAAATGCTCTCGTTGCCGGAATTAAGAAGCTTGGACTTAAACC
TGCTGATGTTAAAGGCACAATGTTTGTATGGGCTGCCATTCCTGACGGCTATACCAGTTCAGCTGATTATGTTATGGAAC
TTCTTAATAAGACTGGCGTTTTATGTACACCTGGAAGCAGCTTCGGAAGCCTTGGAGAAGGTCATGTAAGATTTGCCCTT
GTACTTCCCCATGAAGAAATTGAGAATATTTTTTCTAATCTGTAA

Upstream 100 bases:

>100_bases
AACATTTGCAGACCGCCATATCTTATTTATTTCTACTTACATATATAAAACTATCACATTTTCACCAAAAAATACACCTT
AAAATTGACTTTTGTTAATT

Downstream 100 bases:

>100_bases
TTCACTAAAAAACATAATATACGTACAAAACCCCGTATCCTGCAAAACAGAATACGGGGTTTATATGTATCTTTGCTATT
AACAATCACTGGTAATTAGC

Product: hypothetical protein

Products: NA

Alternate protein names: DAP-AT; DAP-aminotransferase; LL-DAP-aminotransferase [H]

Number of amino acids: Translated: 414; Mature: 414

Protein sequence:

>414_residues
MLVSYSIGLKFFYISGLNKMHADTHLKKWSIHMNIEFSKRADRFGSNIFNILNEKKNDRLAQGKPVYNFTVGTPDFKPDE
SVMKVVSDAALDPENYKYSLGDTDELLDAVCKWYKRRYNTVITPDEVTSVFGTQEGMAHIALALCNPGDLCLVPNPGYPI
FEIGPFLCDAQIAYYNLLPENDYLIDFDSIDEDTAKRAKMMVVSYPLNPVCATAPDEFYDKLIAFAKKYNIIIIHDNAYS
EIIYDGQIGGSFLSHEGAMEVGVEFNSLSKTYNLTGLRLSFLIGNREIVSKFKTVRSQFDYGTSLIYQKAAVAALNGPQE
YVADNRAEYELRRNALVAGIKKLGLKPADVKGTMFVWAAIPDGYTSSADYVMELLNKTGVLCTPGSSFGSLGEGHVRFAL
VLPHEEIENIFSNL

Sequences:

>Translated_414_residues
MLVSYSIGLKFFYISGLNKMHADTHLKKWSIHMNIEFSKRADRFGSNIFNILNEKKNDRLAQGKPVYNFTVGTPDFKPDE
SVMKVVSDAALDPENYKYSLGDTDELLDAVCKWYKRRYNTVITPDEVTSVFGTQEGMAHIALALCNPGDLCLVPNPGYPI
FEIGPFLCDAQIAYYNLLPENDYLIDFDSIDEDTAKRAKMMVVSYPLNPVCATAPDEFYDKLIAFAKKYNIIIIHDNAYS
EIIYDGQIGGSFLSHEGAMEVGVEFNSLSKTYNLTGLRLSFLIGNREIVSKFKTVRSQFDYGTSLIYQKAAVAALNGPQE
YVADNRAEYELRRNALVAGIKKLGLKPADVKGTMFVWAAIPDGYTSSADYVMELLNKTGVLCTPGSSFGSLGEGHVRFAL
VLPHEEIENIFSNL
>Mature_414_residues
MLVSYSIGLKFFYISGLNKMHADTHLKKWSIHMNIEFSKRADRFGSNIFNILNEKKNDRLAQGKPVYNFTVGTPDFKPDE
SVMKVVSDAALDPENYKYSLGDTDELLDAVCKWYKRRYNTVITPDEVTSVFGTQEGMAHIALALCNPGDLCLVPNPGYPI
FEIGPFLCDAQIAYYNLLPENDYLIDFDSIDEDTAKRAKMMVVSYPLNPVCATAPDEFYDKLIAFAKKYNIIIIHDNAYS
EIIYDGQIGGSFLSHEGAMEVGVEFNSLSKTYNLTGLRLSFLIGNREIVSKFKTVRSQFDYGTSLIYQKAAVAALNGPQE
YVADNRAEYELRRNALVAGIKKLGLKPADVKGTMFVWAAIPDGYTSSADYVMELLNKTGVLCTPGSSFGSLGEGHVRFAL
VLPHEEIENIFSNL

Specific function: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=352, Percent_Identity=23.2954545454545, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI56713256, Length=349, Percent_Identity=23.2091690544413, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI95147551, Length=381, Percent_Identity=19.6850393700787, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI169881279, Length=381, Percent_Identity=19.6850393700787, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1788722, Length=379, Percent_Identity=35.6200527704486, Blast_Score=263, Evalue=2e-71,
Organism=Escherichia coli, GI1788627, Length=374, Percent_Identity=24.331550802139, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1786816, Length=352, Percent_Identity=21.0227272727273, Blast_Score=78, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71994472, Length=342, Percent_Identity=24.5614035087719, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71994476, Length=342, Percent_Identity=24.5614035087719, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17567663, Length=313, Percent_Identity=24.9201277955272, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17567369, Length=290, Percent_Identity=23.1034482758621, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322401, Length=388, Percent_Identity=23.4536082474227, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI18859735, Length=395, Percent_Identity=26.0759493670886, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI28573069, Length=383, Percent_Identity=19.0600522193212, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24646114, Length=383, Percent_Identity=19.0600522193212, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI28573067, Length=383, Percent_Identity=19.0600522193212, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI28573065, Length=383, Percent_Identity=19.0600522193212, Blast_Score=72, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR019881
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.83 [H]

Molecular weight: Translated: 46246; Mature: 46246

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVSYSIGLKFFYISGLNKMHADTHLKKWSIHMNIEFSKRADRFGSNIFNILNEKKNDRL
CEEEEECCEEEEEEECCCHHHCCCCEEEEEEEEEEEEHHHHHHHHHHHHHHHCCCCCCCC
AQGKPVYNFTVGTPDFKPDESVMKVVSDAALDPENYKYSLGDTDELLDAVCKWYKRRYNT
CCCCCEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCEECCCCHHHHHHHHHHHHHHHCCC
VITPDEVTSVFGTQEGMAHIALALCNPGDLCLVPNPGYPIFEIGPFLCDAQIAYYNLLPE
CCCHHHHHHHHCCCCCCEEEEEEEECCCCEEEECCCCCCCEECCCHHCCCEEEEEEECCC
NDYLIDFDSIDEDTAKRAKMMVVSYPLNPVCATAPDEFYDKLIAFAKKYNIIIIHDNAYS
CCEEEECCCCCHHHHHHEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCEEEEECCCCC
EIIYDGQIGGSFLSHEGAMEVGVEFNSLSKTYNLTGLRLSFLIGNREIVSKFKTVRSQFD
EEEECCCCCCHHHCCCCCEEECEEECCCCCEECCCCEEEEEEECCHHHHHHHHHHHHHHC
YGTSLIYQKAAVAALNGPQEYVADNRAEYELRRNALVAGIKKLGLKPADVKGTMFVWAAI
CCHHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEC
PDGYTSSADYVMELLNKTGVLCTPGSSFGSLGEGHVRFALVLPHEEIENIFSNL
CCCCCCCHHHHHHHHHCCCEEECCCCCCCCCCCCCEEEEEEECHHHHHHHHHCC
>Mature Secondary Structure
MLVSYSIGLKFFYISGLNKMHADTHLKKWSIHMNIEFSKRADRFGSNIFNILNEKKNDRL
CEEEEECCEEEEEEECCCHHHCCCCEEEEEEEEEEEEHHHHHHHHHHHHHHHCCCCCCCC
AQGKPVYNFTVGTPDFKPDESVMKVVSDAALDPENYKYSLGDTDELLDAVCKWYKRRYNT
CCCCCEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCEECCCCHHHHHHHHHHHHHHHCCC
VITPDEVTSVFGTQEGMAHIALALCNPGDLCLVPNPGYPIFEIGPFLCDAQIAYYNLLPE
CCCHHHHHHHHCCCCCCEEEEEEEECCCCEEEECCCCCCCEECCCHHCCCEEEEEEECCC
NDYLIDFDSIDEDTAKRAKMMVVSYPLNPVCATAPDEFYDKLIAFAKKYNIIIIHDNAYS
CCEEEECCCCCHHHHHHEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCEEEEECCCCC
EIIYDGQIGGSFLSHEGAMEVGVEFNSLSKTYNLTGLRLSFLIGNREIVSKFKTVRSQFD
EEEECCCCCCHHHCCCCCEEECEEECCCCCEECCCCEEEEEEECCHHHHHHHHHHHHHHC
YGTSLIYQKAAVAALNGPQEYVADNRAEYELRRNALVAGIKKLGLKPADVKGTMFVWAAI
CCHHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEC
PDGYTSSADYVMELLNKTGVLCTPGSSFGSLGEGHVRFALVLPHEEIENIFSNL
CCCCCCCHHHHHHHHHCCCEEECCCCCCCCCCCCCEEEEEEECHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA