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The map label for this gene is rnc [H]

Identifier: 238916990

GI number: 238916990

Start: 1071365

End: 1072078

Strand: Reverse

Name: rnc [H]

Synonym: EUBELI_01059

Alternate gene names: 238916990

Gene position: 1072078-1071365 (Counterclockwise)

Preceding gene: 238916991

Following gene: 238916989

Centisome position: 50.0

GC content: 35.85

Gene sequence:

>714_bases
ATGCATAATAAAAATTTATCTGTGTTTATGCAGACTATTGGTTATGATTTCAAAGATATAAGTCTACTTGAAGTTGCTCT
TACTCACAGTTCTTATGCCAATGAGCAGAAAAAAGGAAATTGCTGTGATAATGAAAGAATGGAATTTTTAGGTGATGCTG
TTCTTGAACTTTCATCAAGTGATTATATATATAAGAATCACGCTGAGATGGCTGAAGGAAAGATGACAAGACTTCGTGCC
AGCATTGTATGTGAGCCTACACTTGCTTTATGTGCAAGAGCTATTAAGCTTGATACATTTATAAGACTCGGTAAAGGAGA
AGAGCTTACCGGAGGAAGAAGCAGGGATTCTATCGTATCAGATGCCTGTGAAGCTGTTATAGGAGCCATCTATCTTGATG
GTGGTTTTGCTAATGCAAAAGAATTTGTTAATAAGTTCATTCTTAATGACCTTGACAATAAGAAACTCTTTTTTGATAGC
AAGACTATATTACAGGAAGTTATTCAGGGACTTGGAAAAGAAGTTGATTATGAATTCATCGGTGAAGAAGGTCCTGAACA
TAACAAACAATTCGTTGTAGCTGCTGTAGTTGACGGGCTTTTTAATATTAAAGGAACAGGCCATACTAAGAAATCAGCAT
CTCAGAATGCGGCATATGCTGCACTTATCGAGCTTAAGAATAAAGGCTACGATATCAACTCTGATAAGAAATAA

Upstream 100 bases:

>100_bases
CATACAGATTGTGATGAAAACTAAGAGCATAAGGAGCAAATATTCTTGCATAATTTGTTCCTTATGCTCTTGTTTTCAAA
AGTTCGCAGAAAGGTGTATT

Downstream 100 bases:

>100_bases
TAAGTGAGGGGTTATGTATTTAAAAAGTATAGAAGTACAGGGATTTAAGTCATTTGCTAATAAGATAGTATTTGACTTTC
ATAATGGTATTACAGGTATT

Product: ribonuclease III

Products: NA

Alternate protein names: Ribonuclease III; RNase III [H]

Number of amino acids: Translated: 237; Mature: 237

Protein sequence:

>237_residues
MHNKNLSVFMQTIGYDFKDISLLEVALTHSSYANEQKKGNCCDNERMEFLGDAVLELSSSDYIYKNHAEMAEGKMTRLRA
SIVCEPTLALCARAIKLDTFIRLGKGEELTGGRSRDSIVSDACEAVIGAIYLDGGFANAKEFVNKFILNDLDNKKLFFDS
KTILQEVIQGLGKEVDYEFIGEEGPEHNKQFVVAAVVDGLFNIKGTGHTKKSASQNAAYAALIELKNKGYDINSDKK

Sequences:

>Translated_237_residues
MHNKNLSVFMQTIGYDFKDISLLEVALTHSSYANEQKKGNCCDNERMEFLGDAVLELSSSDYIYKNHAEMAEGKMTRLRA
SIVCEPTLALCARAIKLDTFIRLGKGEELTGGRSRDSIVSDACEAVIGAIYLDGGFANAKEFVNKFILNDLDNKKLFFDS
KTILQEVIQGLGKEVDYEFIGEEGPEHNKQFVVAAVVDGLFNIKGTGHTKKSASQNAAYAALIELKNKGYDINSDKK
>Mature_237_residues
MHNKNLSVFMQTIGYDFKDISLLEVALTHSSYANEQKKGNCCDNERMEFLGDAVLELSSSDYIYKNHAEMAEGKMTRLRA
SIVCEPTLALCARAIKLDTFIRLGKGEELTGGRSRDSIVSDACEAVIGAIYLDGGFANAKEFVNKFILNDLDNKKLFFDS
KTILQEVIQGLGKEVDYEFIGEEGPEHNKQFVVAAVVDGLFNIKGTGHTKKSASQNAAYAALIELKNKGYDINSDKK

Specific function: Digests double-stranded RNA. Involved in the processing of ribosomal RNA precursors and of some mRNAs [H]

COG id: COG0571

COG function: function code K; dsRNA-specific ribonuclease

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RNase III domain [H]

Homologues:

Organism=Homo sapiens, GI155030236, Length=116, Percent_Identity=33.6206896551724, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI155030234, Length=116, Percent_Identity=33.6206896551724, Blast_Score=79, Evalue=3e-15,
Organism=Escherichia coli, GI1788920, Length=210, Percent_Identity=33.8095238095238, Blast_Score=112, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17506883, Length=210, Percent_Identity=30.952380952381, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI193202651, Length=210, Percent_Identity=30.952380952381, Blast_Score=77, Evalue=6e-15,
Organism=Drosophila melanogaster, GI17137682, Length=234, Percent_Identity=29.4871794871795, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001159
- InterPro:   IPR014720
- InterPro:   IPR000999
- InterPro:   IPR011907 [H]

Pfam domain/function: PF00035 dsrm; PF00636 Ribonuclease_3 [H]

EC number: =3.1.26.3 [H]

Molecular weight: Translated: 26211; Mature: 26211

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: PS50137 DS_RBD ; PS00517 RNASE_3_1 ; PS50142 RNASE_3_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHNKNLSVFMQTIGYDFKDISLLEVALTHSSYANEQKKGNCCDNERMEFLGDAVLELSSS
CCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCC
DYIYKNHAEMAEGKMTRLRASIVCEPTLALCARAIKLDTFIRLGKGEELTGGRSRDSIVS
CCEECCCHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHH
DACEAVIGAIYLDGGFANAKEFVNKFILNDLDNKKLFFDSKTILQEVIQGLGKEVDYEFI
HHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHCCCCCCHHCC
GEEGPEHNKQFVVAAVVDGLFNIKGTGHTKKSASQNAAYAALIELKNKGYDINSDKK
CCCCCCCCHHEEHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHEEHHCCCCCCCCCCC
>Mature Secondary Structure
MHNKNLSVFMQTIGYDFKDISLLEVALTHSSYANEQKKGNCCDNERMEFLGDAVLELSSS
CCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCC
DYIYKNHAEMAEGKMTRLRASIVCEPTLALCARAIKLDTFIRLGKGEELTGGRSRDSIVS
CCEECCCHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHH
DACEAVIGAIYLDGGFANAKEFVNKFILNDLDNKKLFFDSKTILQEVIQGLGKEVDYEFI
HHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHCCCCCCHHCC
GEEGPEHNKQFVVAAVVDGLFNIKGTGHTKKSASQNAAYAALIELKNKGYDINSDKK
CCCCCCCCHHEEHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHEEHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]