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The map label for this gene is gpsA [H]

Identifier: 238916969

GI number: 238916969

Start: 1051471

End: 1052511

Strand: Reverse

Name: gpsA [H]

Synonym: EUBELI_01038

Alternate gene names: 238916969

Gene position: 1052511-1051471 (Counterclockwise)

Preceding gene: 238916970

Following gene: 238916968

Centisome position: 49.09

GC content: 40.25

Gene sequence:

>1041_bases
ATGCGCTTATGCGCAGATTGGAGTATAATTATGGCAAATGTAAGTGTTTTAGGAGCAGGAAGCTGGGGCTTAGGTCTGGC
TTTACTTCTTAATAACAACGGACACAATGTAACAGTATGGTCAGTTTTAAAGGATGAAGTTGACATGCTTCAGACTGAAA
GAGAACATAAAAGATGCCTTCCGGGTGTAAAGATTCCTGATAGTATTACTATTTCAGGAGATACAGAGAATGTAATTAAC
AGTGCAGATGTACTTGTACTTGCAGTTGCATCTCCTTATACACGTTCTACTGCAAAGCTGATTGCACCTTTCGTAAAGGA
AGGACAGATTATTGTAAATGTGGCAAAAGGTGTTGAGGAGCATACTTTATTAACACTCTGCCAGATTGTAGAAGAGGAGA
TTCCTTGTGCCAAGGTTGCTGTTTTATCAGGACCAAGCCACGCTGAAGAGGTAAGCCGTGGTATTCCTACAACATGTGTC
ATAGGTGCACATGAAAAGGCAACCGCTGAATATTTACAGAACATTTTTATGAGTGATGTATTCAGGGTATATACAAGTCC
TGATATGCTTGGAATATGCATAGGTGGTGCATTAAAGAATGTTATCGCGCTTGCTGCAGGTATTGCGGATGGGCTTGGCT
ATGGTGATAATACTAAAGCTGCTCTTATAACAAGGGGTAATGCTGAGATAACAAGACTTGGTGTTGCGATGGGAGCTAAT
CCTCATACTTTTGCTGGTCTTTCAGGTATTGGTGACTTAATCGTTACATGTGCAAGTATGCACAGCCGTAACAGACGTGC
AGGAATCCTCATAGGTAAAGGATACACCAAAGACGAGGCTATGAAAGAAGTGCAGATGGTAGTAGAAGGTGTGTTCTCTG
CAAAGGCAGCGTTAGAACTTTCTAAGAAATATAATATTGAGATGCCGATTGTAGAGCAGGTTAATAAGGTGCTTTTTGAA
GACAAGCCTGCTGCTGAAGCTGTTAAAGAACTTATGTTAAGAGACAAGAAAATTGAAATAGATAATTCTGAATGGAAATA
A

Upstream 100 bases:

>100_bases
CGCTCTTGCAGCGCTTGCATTTATCAGACACCGCAGTAATATTGTAAGACTGGTTCAGGGAACAGAACGAAAAATCGGTG
AAAAAAAGAATTAATTTTTG

Downstream 100 bases:

>100_bases
TAATCAGTTTTATCTGAGCCTGATTAAAAGAGGGGGATACCAATGGCTCATATCCGTAATTTAACTAACAGGGCATATAT
ATCCAACAGTCTGAAAGAAT

Product: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase [H]

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MRLCADWSIIMANVSVLGAGSWGLGLALLLNNNGHNVTVWSVLKDEVDMLQTEREHKRCLPGVKIPDSITISGDTENVIN
SADVLVLAVASPYTRSTAKLIAPFVKEGQIIVNVAKGVEEHTLLTLCQIVEEEIPCAKVAVLSGPSHAEEVSRGIPTTCV
IGAHEKATAEYLQNIFMSDVFRVYTSPDMLGICIGGALKNVIALAAGIADGLGYGDNTKAALITRGNAEITRLGVAMGAN
PHTFAGLSGIGDLIVTCASMHSRNRRAGILIGKGYTKDEAMKEVQMVVEGVFSAKAALELSKKYNIEMPIVEQVNKVLFE
DKPAAEAVKELMLRDKKIEIDNSEWK

Sequences:

>Translated_346_residues
MRLCADWSIIMANVSVLGAGSWGLGLALLLNNNGHNVTVWSVLKDEVDMLQTEREHKRCLPGVKIPDSITISGDTENVIN
SADVLVLAVASPYTRSTAKLIAPFVKEGQIIVNVAKGVEEHTLLTLCQIVEEEIPCAKVAVLSGPSHAEEVSRGIPTTCV
IGAHEKATAEYLQNIFMSDVFRVYTSPDMLGICIGGALKNVIALAAGIADGLGYGDNTKAALITRGNAEITRLGVAMGAN
PHTFAGLSGIGDLIVTCASMHSRNRRAGILIGKGYTKDEAMKEVQMVVEGVFSAKAALELSKKYNIEMPIVEQVNKVLFE
DKPAAEAVKELMLRDKKIEIDNSEWK
>Mature_346_residues
MRLCADWSIIMANVSVLGAGSWGLGLALLLNNNGHNVTVWSVLKDEVDMLQTEREHKRCLPGVKIPDSITISGDTENVIN
SADVLVLAVASPYTRSTAKLIAPFVKEGQIIVNVAKGVEEHTLLTLCQIVEEEIPCAKVAVLSGPSHAEEVSRGIPTTCV
IGAHEKATAEYLQNIFMSDVFRVYTSPDMLGICIGGALKNVIALAAGIADGLGYGDNTKAALITRGNAEITRLGVAMGAN
PHTFAGLSGIGDLIVTCASMHSRNRRAGILIGKGYTKDEAMKEVQMVVEGVFSAKAALELSKKYNIEMPIVEQVNKVLFE
DKPAAEAVKELMLRDKKIEIDNSEWK

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI33695088, Length=339, Percent_Identity=27.1386430678466, Blast_Score=113, Evalue=2e-25,
Organism=Homo sapiens, GI24307999, Length=336, Percent_Identity=26.1904761904762, Blast_Score=106, Evalue=3e-23,
Organism=Escherichia coli, GI1790037, Length=333, Percent_Identity=37.8378378378378, Blast_Score=242, Evalue=3e-65,
Organism=Caenorhabditis elegans, GI32564399, Length=344, Percent_Identity=30.2325581395349, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI32564403, Length=352, Percent_Identity=29.2613636363636, Blast_Score=104, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI193210136, Length=348, Percent_Identity=29.3103448275862, Blast_Score=104, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI17507425, Length=338, Percent_Identity=24.8520710059172, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI193210134, Length=337, Percent_Identity=27.5964391691395, Blast_Score=91, Evalue=7e-19,
Organism=Saccharomyces cerevisiae, GI6324513, Length=362, Percent_Identity=26.7955801104972, Blast_Score=97, Evalue=5e-21,
Organism=Saccharomyces cerevisiae, GI6320181, Length=358, Percent_Identity=25.1396648044693, Blast_Score=94, Evalue=3e-20,
Organism=Drosophila melanogaster, GI17136202, Length=295, Percent_Identity=29.8305084745763, Blast_Score=105, Evalue=6e-23,
Organism=Drosophila melanogaster, GI17136200, Length=295, Percent_Identity=29.8305084745763, Blast_Score=105, Evalue=6e-23,
Organism=Drosophila melanogaster, GI17136204, Length=295, Percent_Identity=29.8305084745763, Blast_Score=105, Evalue=6e-23,
Organism=Drosophila melanogaster, GI22026922, Length=350, Percent_Identity=26, Blast_Score=101, Evalue=7e-22,
Organism=Drosophila melanogaster, GI45551945, Length=236, Percent_Identity=26.6949152542373, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24648969, Length=191, Percent_Identity=27.7486910994764, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI281362270, Length=236, Percent_Identity=26.6949152542373, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040 [H]

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N [H]

EC number: =1.1.1.94 [H]

Molecular weight: Translated: 37141; Mature: 37141

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: PS00957 NAD_G3PDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLCADWSIIMANVSVLGAGSWGLGLALLLNNNGHNVTVWSVLKDEVDMLQTEREHKRCL
CCEECCHHEEEEEHEEEECCCCCCEEEEEEECCCCEEEEEHHHHHHHHHHHHHHHHHHCC
PGVKIPDSITISGDTENVINSADVLVLAVASPYTRSTAKLIAPFVKEGQIIVNVAKGVEE
CCCCCCCCEEECCCCHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHCCEEEEEECCCCHH
HTLLTLCQIVEEEIPCAKVAVLSGPSHAEEVSRGIPTTCVIGAHEKATAEYLQNIFMSDV
HHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHH
FRVYTSPDMLGICIGGALKNVIALAAGIADGLGYGDNTKAALITRGNAEITRLGVAMGAN
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCEEEEEEEECCC
PHTFAGLSGIGDLIVTCASMHSRNRRAGILIGKGYTKDEAMKEVQMVVEGVFSAKAALEL
CCHHCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
SKKYNIEMPIVEQVNKVLFEDKPAAEAVKELMLRDKKIEIDNSEWK
HHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCEEECCCCCCC
>Mature Secondary Structure
MRLCADWSIIMANVSVLGAGSWGLGLALLLNNNGHNVTVWSVLKDEVDMLQTEREHKRCL
CCEECCHHEEEEEHEEEECCCCCCEEEEEEECCCCEEEEEHHHHHHHHHHHHHHHHHHCC
PGVKIPDSITISGDTENVINSADVLVLAVASPYTRSTAKLIAPFVKEGQIIVNVAKGVEE
CCCCCCCCEEECCCCHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHCCEEEEEECCCCHH
HTLLTLCQIVEEEIPCAKVAVLSGPSHAEEVSRGIPTTCVIGAHEKATAEYLQNIFMSDV
HHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHH
FRVYTSPDMLGICIGGALKNVIALAAGIADGLGYGDNTKAALITRGNAEITRLGVAMGAN
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCEEEEEEEECCC
PHTFAGLSGIGDLIVTCASMHSRNRRAGILIGKGYTKDEAMKEVQMVVEGVFSAKAALEL
CCHHCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
SKKYNIEMPIVEQVNKVLFEDKPAAEAVKELMLRDKKIEIDNSEWK
HHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA