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The map label for this gene is coaD

Identifier: 238916966

GI number: 238916966

Start: 1047871

End: 1048356

Strand: Reverse

Name: coaD

Synonym: EUBELI_01035

Alternate gene names: 238916966

Gene position: 1048356-1047871 (Counterclockwise)

Preceding gene: 238916967

Following gene: 238916965

Centisome position: 48.89

GC content: 35.6

Gene sequence:

>486_bases
GTGAAGAAAGCAATTTATCCAGGAAGCTTTGACCCGGTAACATTAGGACATTTGGATATAATAAGGCGTTCAGCAAGTCT
TGTCGATCATTTAATAGTTGGTGTACTTAATAACAGTACCAAAACACCATTGTTTTCAGTAGAAGAGCGTGTTAATATGT
TAAGGGAAGTCACTAAGGACTTGTCTAATGTTGAAGTATTAAGCTTCAGTGGTCTTTTGGTTGATTTCGCTGCAGAACAT
AATGTATCTGTTATTATAAGGGGATTAAGAGCTGTTACTGATTTTGAATATGAACTTGCCATGTCACAGACAAACAGAGT
TGCAGCTCCTGGAATTGACACTATATTCCTTACAACAAGCCTGAAATATGCTTACTTAAGTTCAAGTATTGTAAAGGAAA
TGGCTATGTATGGGGGAGATATTCATAAGTTCGTTCCAGAAGAGATAATTGACAGAGTATATGAAAAATATGGGATTAAG
CAATAA

Upstream 100 bases:

>100_bases
CTTTAGATTATATTAATGAGTGTGGTTTTGAGACAATAAAAGTCAAAAATTATAAAACAAACAAGCACATATTTATAAGA
CTAAAGGAGAGTGAATAACT

Downstream 100 bases:

>100_bases
AACACTAATAAAGGAGTATTACCATGAGTAGAATTGAGCAATTAATAAGTGATATTGAGAGTTATATAGATAATTGTAAA
TATTATCCATTATCTAATGT

Product: pantetheine-phosphate adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 161; Mature: 161

Protein sequence:

>161_residues
MKKAIYPGSFDPVTLGHLDIIRRSASLVDHLIVGVLNNSTKTPLFSVEERVNMLREVTKDLSNVEVLSFSGLLVDFAAEH
NVSVIIRGLRAVTDFEYELAMSQTNRVAAPGIDTIFLTTSLKYAYLSSSIVKEMAMYGGDIHKFVPEEIIDRVYEKYGIK
Q

Sequences:

>Translated_161_residues
MKKAIYPGSFDPVTLGHLDIIRRSASLVDHLIVGVLNNSTKTPLFSVEERVNMLREVTKDLSNVEVLSFSGLLVDFAAEH
NVSVIIRGLRAVTDFEYELAMSQTNRVAAPGIDTIFLTTSLKYAYLSSSIVKEMAMYGGDIHKFVPEEIIDRVYEKYGIK
Q
>Mature_161_residues
MKKAIYPGSFDPVTLGHLDIIRRSASLVDHLIVGVLNNSTKTPLFSVEERVNMLREVTKDLSNVEVLSFSGLLVDFAAEH
NVSVIIRGLRAVTDFEYELAMSQTNRVAAPGIDTIFLTTSLKYAYLSSSIVKEMAMYGGDIHKFVPEEIIDRVYEKYGIK
Q

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family

Homologues:

Organism=Escherichia coli, GI1790065, Length=148, Percent_Identity=45.2702702702703, Blast_Score=160, Evalue=3e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_EUBE2 (C4Z0C3)

Other databases:

- EMBL:   CP001104
- RefSeq:   YP_002930483.1
- ProteinModelPortal:   C4Z0C3
- GeneID:   7958449
- GenomeReviews:   CP001104_GR
- KEGG:   eel:EUBELI_01035
- OMA:   VRQIAAM
- ProtClustDB:   CLSK2506132
- GO:   GO:0005737
- HAMAP:   MF_00151
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01020
- TIGRFAMs:   TIGR01510
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 18001; Mature: 18001

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKAIYPGSFDPVTLGHLDIIRRSASLVDHLIVGVLNNSTKTPLFSVEERVNMLREVTKD
CCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
LSNVEVLSFSGLLVDFAAEHNVSVIIRGLRAVTDFEYELAMSQTNRVAAPGIDTIFLTTS
HCCCEEEECCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEHH
LKYAYLSSSIVKEMAMYGGDIHKFVPEEIIDRVYEKYGIKQ
HHHHHHHHHHHHHHHHHCCHHHHHCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKKAIYPGSFDPVTLGHLDIIRRSASLVDHLIVGVLNNSTKTPLFSVEERVNMLREVTKD
CCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
LSNVEVLSFSGLLVDFAAEHNVSVIIRGLRAVTDFEYELAMSQTNRVAAPGIDTIFLTTS
HCCCEEEECCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEHH
LKYAYLSSSIVKEMAMYGGDIHKFVPEEIIDRVYEKYGIKQ
HHHHHHHHHHHHHHHHHCCHHHHHCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA