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The map label for this gene is cdd [H]

Identifier: 238916904

GI number: 238916904

Start: 988417

End: 988797

Strand: Direct

Name: cdd [H]

Synonym: EUBELI_00973

Alternate gene names: 238916904

Gene position: 988417-988797 (Clockwise)

Preceding gene: 238916903

Following gene: 238916905

Centisome position: 46.1

GC content: 40.42

Gene sequence:

>381_bases
ATGACAGATAATGAACTTGTTGCTAAAGCTAAAGAGGCACTTGAGAACTCATATTCACCGTATTCACATTTTGCAGTTGG
TGCGGCACTTTTAAGTACTGATGGACAGGTATTTATAGGCTGTAATATTGAGAATTCTTCTTTCGGGGCTACTAACTGTG
CAGAAAGAACTGCAATATTTAAGGCGGTCAGTGAGGGTGTAAAGGATTTTAAGGCGATTGCTATTGTATGTTCAGGAGAC
CAGCCTGCTTATCCGTGTGGAATATGCAGACAGGTGATGTCTGAATTTTTCAATCCTGATACAAGAATTATTGTTGAGGA
AGGCGGCGGGCTTAAGACTTATACAATGAGTGAAATTCTGCCAGACAGCTTTTCGTTATAG

Upstream 100 bases:

>100_bases
TGGTTATGACCACATGACACCAGAAGAAAGTGCAGTTATGGAAGCAAAGCAGAATGAAGTACTTGAAAGACTTGGAATTA
CCCGTTAAGAGGTGACATAT

Downstream 100 bases:

>100_bases
TATAATATTGCTTATAAATGTTAATACTTCCCAGTAAGGACAACTTACAGGAGGGAGTATTGATGAATAAGAAATCATTC
TGGCTTTATGTTGTGATTAT

Product: cytidine deaminase

Products: NA

Alternate protein names: CDA; Cytidine aminohydrolase [H]

Number of amino acids: Translated: 126; Mature: 125

Protein sequence:

>126_residues
MTDNELVAKAKEALENSYSPYSHFAVGAALLSTDGQVFIGCNIENSSFGATNCAERTAIFKAVSEGVKDFKAIAIVCSGD
QPAYPCGICRQVMSEFFNPDTRIIVEEGGGLKTYTMSEILPDSFSL

Sequences:

>Translated_126_residues
MTDNELVAKAKEALENSYSPYSHFAVGAALLSTDGQVFIGCNIENSSFGATNCAERTAIFKAVSEGVKDFKAIAIVCSGD
QPAYPCGICRQVMSEFFNPDTRIIVEEGGGLKTYTMSEILPDSFSL
>Mature_125_residues
TDNELVAKAKEALENSYSPYSHFAVGAALLSTDGQVFIGCNIENSSFGATNCAERTAIFKAVSEGVKDFKAIAIVCSGDQ
PAYPCGICRQVMSEFFNPDTRIIVEEGGGLKTYTMSEILPDSFSL

Specific function: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis [H]

COG id: COG0295

COG function: function code F; Cytidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI11386157, Length=122, Percent_Identity=50, Blast_Score=115, Evalue=8e-27,
Organism=Caenorhabditis elegans, GI17540514, Length=127, Percent_Identity=44.8818897637795, Blast_Score=112, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI17551074, Length=125, Percent_Identity=44, Blast_Score=105, Evalue=7e-24,
Organism=Saccharomyces cerevisiae, GI6323274, Length=129, Percent_Identity=39.5348837209302, Blast_Score=94, Evalue=9e-21,
Organism=Drosophila melanogaster, GI24582741, Length=128, Percent_Identity=43.75, Blast_Score=105, Evalue=7e-24,
Organism=Drosophila melanogaster, GI19920920, Length=119, Percent_Identity=42.8571428571429, Blast_Score=94, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24582744, Length=103, Percent_Identity=44.6601941747573, Blast_Score=88, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002125
- InterPro:   IPR006262
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: =3.5.4.5 [H]

Molecular weight: Translated: 13519; Mature: 13388

Theoretical pI: Translated: 4.27; Mature: 4.27

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
4.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDNELVAKAKEALENSYSPYSHFAVGAALLSTDGQVFIGCNIENSSFGATNCAERTAIF
CCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHH
KAVSEGVKDFKAIAIVCSGDQPAYPCGICRQVMSEFFNPDTRIIVEEGGGLKTYTMSEIL
HHHHHHHHHHEEEEEEECCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCEEEEEHHHHC
PDSFSL
CCCCCC
>Mature Secondary Structure 
TDNELVAKAKEALENSYSPYSHFAVGAALLSTDGQVFIGCNIENSSFGATNCAERTAIF
CCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHH
KAVSEGVKDFKAIAIVCSGDQPAYPCGICRQVMSEFFNPDTRIIVEEGGGLKTYTMSEIL
HHHHHHHHHHEEEEEEECCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCEEEEEHHHHC
PDSFSL
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11739901 [H]