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The map label for this gene is recG [H]

Identifier: 238916890

GI number: 238916890

Start: 974932

End: 976989

Strand: Direct

Name: recG [H]

Synonym: EUBELI_00959

Alternate gene names: 238916890

Gene position: 974932-976989 (Clockwise)

Preceding gene: 238916889

Following gene: 238916891

Centisome position: 45.47

GC content: 39.94

Gene sequence:

>2058_bases
ATGAATATAACAGAATTAAAGGGAATCGGCGCTAAGACAGCTGAGAATTTTAACAGGCTTTCGGTATACACAGTATCGGA
TCTCGTGGGGTTATACCCACGGGATTACGATGTATACCATGAGCCTGTTTTTGTTAAAGATATAAGCCATGAATCAGAGC
ATACAGAGGTAGCTGTTGAAGGACAGGTATGCAAAAGCCCGGATATATATGGGAGCGGCAGGCTTAAGATATTAACTGTG
ACTATAAAGGATTATAATGGCGACTCCATAAAATGTAGCTGGTATAATATGCCATTTTTAAAGAATACATTAAGGCTTGG
CGCAAGATATGTATTCAGGGGAAGGCTGGTTAATAAAAGAGGCTGGTTATTAGAACAGCCGAAAATGTATACACTTGCCC
AGTATAAGGAACTTCAGGGAACACTGCAGCCAATATATCCTCTGACTAAAGGTCTTACTAACAATACTGTTACTAAGGCA
GTTGCACAGGCACTTGAAAAATACAGCGCGGGACTTGAAAAGGAATATATACCTGATTATATAAGAAAGAGATATTCGCT
TGCTGAGCATAATTTCAGTATTGTTAATATACATTTTCCTAAGACAATGGAAGAATATGTTCAGGCGAGACACAGACTTG
CATTTGAAGAGTTTTTTTTATTCACGCTAGCAACTCTTTCATTAAAGAGTGCAAATGAACACATACCGAACAGCTATGTA
ATACCAGAAAGCAAAGAAAAGGATCAATTCCTTGAAAGCCTGTCATATTCACTTACCAATGCACAGTTAAGGACTGTGTC
AGAGGTTGCACAAGATATGTCAGGTGAACACCTGTGCAGCCGTCTGATACAGGGAGATGTAGGTTCAGGAAAGACAGTTG
TTGCAACAATTGCACTTATCAATACGGTTATTGCAGGATATCAGGGAGCATTGATGGCACCAACAGAGGTTCTTGCAAGA
CAGCATTATGAATCGTTTGTTAAAGGCTTTGAAAAGGCGGGACTTGATATCAGAGTTGAACTTCTTGTTGGTTCAATGAC
AGCGAAACAGAAAAAGGAAGCATATGCAAGGATTGCAGATGGAACTGCCGGAATAATAGTAGGAACGCATGCGTTGATAC
AGGAAAAGGTTGAATATAAAGAACTGGCACTTGTTATAACAGATGAGCAGCACAGATTCGGAGTAAACCAGCGCCGTGAC
TTTTCGCAGAAAGGGAAAAGCCCGCATATTCTTGTAATGAGTGCAACGCCAATACCAAGAACTCTGGCAATTATACTGTA
CGGTGACCTTGATATATCAATAATTGATGAGATGCCTGCGAACAGACTTCCTATAAAGAATTGTGTTGTGGATGAAAGCT
ACAGACCGAAGGCGTATACATTTATACACAAGCAGGTTGCTTCCGGCAGACAATGCTATGTAATATGTCCGATGGTTGAG
GACAGTGAGGCTGTAGAGGCCGAAAATGTTGTTGATTACACGGCAATGCTTAAGAAAGAACTTCCAGATATAAGGATAGA
ATATCTTCATGGAAAGATGCGTCCATCGTTAAAGAATGAGGTGATGGAAAGATTTGCAGCACATGAAACGGATGTGCTAG
TATCAACTACAGTTATCGAGGTTGGTGTAAATGTGCCTAACAGCACTGTTATGATGGTAGAGAATTCGGAAAGATTTGGG
CTTGCACAGCTTCATCAGTTAAGAGGCCGTGTTGGGCGAGGAGAATATCAGTCATATTGTATATTTGTTACAGGCAATAA
GTCAGAGAAGATAAGAAAAAGACTGGAAATTCTTAATAAATCCAACGATGGATTCAAGATAGCTGAGGAAGATTTAAGAC
TGCGTGGACCGGGAGATTTCTTCGGGGTAAGGCAGAGCGGTGATTTTGATTTCGGAATAGCAGATGTATTTACTGATGCA
AAGACATTAAAGGAAGCGTCAGATGCAGCGAAAGATATGCTAAAGAAAGATCCTGAGTTAAAGCTTGAGAATAATGTATA
TCTAAAGCAGAAGGTTGCAGAGTATACGATTAAATGTTTAGAAAAGATTAATCTGTAA

Upstream 100 bases:

>100_bases
TTGTTTCTAAGATTGAAGAAAAGTTTCCTGATGTAGATGTTGAACTTCAGTTTGGTGGACAGCCGGTTTATTATTATATT
GTATCTGTTGAGTAAGAATT

Downstream 100 bases:

>100_bases
AGGAGATGTATGCACATGAGACAGATGGAATTCACAATGAGCAGACCTAATCTTGTCAAGCCAGGAGATGAGGTAGATAT
TACGGAGGGTAAGCTTCCTA

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 685; Mature: 685

Protein sequence:

>685_residues
MNITELKGIGAKTAENFNRLSVYTVSDLVGLYPRDYDVYHEPVFVKDISHESEHTEVAVEGQVCKSPDIYGSGRLKILTV
TIKDYNGDSIKCSWYNMPFLKNTLRLGARYVFRGRLVNKRGWLLEQPKMYTLAQYKELQGTLQPIYPLTKGLTNNTVTKA
VAQALEKYSAGLEKEYIPDYIRKRYSLAEHNFSIVNIHFPKTMEEYVQARHRLAFEEFFLFTLATLSLKSANEHIPNSYV
IPESKEKDQFLESLSYSLTNAQLRTVSEVAQDMSGEHLCSRLIQGDVGSGKTVVATIALINTVIAGYQGALMAPTEVLAR
QHYESFVKGFEKAGLDIRVELLVGSMTAKQKKEAYARIADGTAGIIVGTHALIQEKVEYKELALVITDEQHRFGVNQRRD
FSQKGKSPHILVMSATPIPRTLAIILYGDLDISIIDEMPANRLPIKNCVVDESYRPKAYTFIHKQVASGRQCYVICPMVE
DSEAVEAENVVDYTAMLKKELPDIRIEYLHGKMRPSLKNEVMERFAAHETDVLVSTTVIEVGVNVPNSTVMMVENSERFG
LAQLHQLRGRVGRGEYQSYCIFVTGNKSEKIRKRLEILNKSNDGFKIAEEDLRLRGPGDFFGVRQSGDFDFGIADVFTDA
KTLKEASDAAKDMLKKDPELKLENNVYLKQKVAEYTIKCLEKINL

Sequences:

>Translated_685_residues
MNITELKGIGAKTAENFNRLSVYTVSDLVGLYPRDYDVYHEPVFVKDISHESEHTEVAVEGQVCKSPDIYGSGRLKILTV
TIKDYNGDSIKCSWYNMPFLKNTLRLGARYVFRGRLVNKRGWLLEQPKMYTLAQYKELQGTLQPIYPLTKGLTNNTVTKA
VAQALEKYSAGLEKEYIPDYIRKRYSLAEHNFSIVNIHFPKTMEEYVQARHRLAFEEFFLFTLATLSLKSANEHIPNSYV
IPESKEKDQFLESLSYSLTNAQLRTVSEVAQDMSGEHLCSRLIQGDVGSGKTVVATIALINTVIAGYQGALMAPTEVLAR
QHYESFVKGFEKAGLDIRVELLVGSMTAKQKKEAYARIADGTAGIIVGTHALIQEKVEYKELALVITDEQHRFGVNQRRD
FSQKGKSPHILVMSATPIPRTLAIILYGDLDISIIDEMPANRLPIKNCVVDESYRPKAYTFIHKQVASGRQCYVICPMVE
DSEAVEAENVVDYTAMLKKELPDIRIEYLHGKMRPSLKNEVMERFAAHETDVLVSTTVIEVGVNVPNSTVMMVENSERFG
LAQLHQLRGRVGRGEYQSYCIFVTGNKSEKIRKRLEILNKSNDGFKIAEEDLRLRGPGDFFGVRQSGDFDFGIADVFTDA
KTLKEASDAAKDMLKKDPELKLENNVYLKQKVAEYTIKCLEKINL
>Mature_685_residues
MNITELKGIGAKTAENFNRLSVYTVSDLVGLYPRDYDVYHEPVFVKDISHESEHTEVAVEGQVCKSPDIYGSGRLKILTV
TIKDYNGDSIKCSWYNMPFLKNTLRLGARYVFRGRLVNKRGWLLEQPKMYTLAQYKELQGTLQPIYPLTKGLTNNTVTKA
VAQALEKYSAGLEKEYIPDYIRKRYSLAEHNFSIVNIHFPKTMEEYVQARHRLAFEEFFLFTLATLSLKSANEHIPNSYV
IPESKEKDQFLESLSYSLTNAQLRTVSEVAQDMSGEHLCSRLIQGDVGSGKTVVATIALINTVIAGYQGALMAPTEVLAR
QHYESFVKGFEKAGLDIRVELLVGSMTAKQKKEAYARIADGTAGIIVGTHALIQEKVEYKELALVITDEQHRFGVNQRRD
FSQKGKSPHILVMSATPIPRTLAIILYGDLDISIIDEMPANRLPIKNCVVDESYRPKAYTFIHKQVASGRQCYVICPMVE
DSEAVEAENVVDYTAMLKKELPDIRIEYLHGKMRPSLKNEVMERFAAHETDVLVSTTVIEVGVNVPNSTVMMVENSERFG
LAQLHQLRGRVGRGEYQSYCIFVTGNKSEKIRKRLEILNKSNDGFKIAEEDLRLRGPGDFFGVRQSGDFDFGIADVFTDA
KTLKEASDAAKDMLKKDPELKLENNVYLKQKVAEYTIKCLEKINL

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=681, Percent_Identity=36.7107195301028, Blast_Score=408, Evalue=1e-115,
Organism=Escherichia coli, GI1787357, Length=387, Percent_Identity=36.4341085271318, Blast_Score=239, Evalue=4e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 77377; Mature: 77377

Theoretical pI: Translated: 7.42; Mature: 7.42

Prosite motif: PS00435 PEROXIDASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNITELKGIGAKTAENFNRLSVYTVSDLVGLYPRDYDVYHEPVFVKDISHESEHTEVAVE
CCCCCCCCCCCHHHCCCCEEEEEEHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCEEEEE
GQVCKSPDIYGSGRLKILTVTIKDYNGDSIKCSWYNMPFLKNTLRLGARYVFRGRLVNKR
CCCCCCCCCCCCCEEEEEEEEEEECCCCEEEEEEECCHHHHHHHHHHHHEEEECEEECCC
GWLLEQPKMYTLAQYKELQGTLQPIYPLTKGLTNNTVTKAVAQALEKYSAGLEKEYIPDY
CCEECCCCHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHH
IRKRYSLAEHNFSIVNIHFPKTMEEYVQARHRLAFEEFFLFTLATLSLKSANEHIPNSYV
HHHHHHHHHCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEE
IPESKEKDQFLESLSYSLTNAQLRTVSEVAQDMSGEHLCSRLIQGDVGSGKTVVATIALI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHH
NTVIAGYQGALMAPTEVLARQHYESFVKGFEKAGLDIRVELLVGSMTAKQKKEAYARIAD
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHCC
GTAGIIVGTHALIQEKVEYKELALVITDEQHRFGVNQRRDFSQKGKSPHILVMSATPIPR
CCCEEEECHHHHHHHHHCCEEEEEEEECCHHHCCCCCCCCHHHCCCCCEEEEEECCCCCC
TLAIILYGDLDISIIDEMPANRLPIKNCVVDESYRPKAYTFIHKQVASGRQCYVICPMVE
EEEEEEEECCCEEEECCCCCCCCCHHHEEECCCCCCCHHHHHHHHHHCCCEEEEEEEECC
DSEAVEAENVVDYTAMLKKELPDIRIEYLHGKMRPSLKNEVMERFAAHETDVLVSTTVIE
CCCHHHHHHHHHHHHHHHHCCCCCEEEEHHCCCCCHHHHHHHHHHHCCCCCEEEEEEEEE
VGVNVPNSTVMMVENSERFGLAQLHQLRGRVGRGEYQSYCIFVTGNKSEKIRKRLEILNK
EECCCCCCEEEEEECCCCCCHHHHHHHHCCCCCCCCCEEEEEEECCCHHHHHHHHHHHCC
SNDGFKIAEEDLRLRGPGDFFGVRQSGDFDFGIADVFTDAKTLKEASDAAKDMLKKDPEL
CCCCCEEECCCCEECCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
KLENNVYLKQKVAEYTIKCLEKINL
EECCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNITELKGIGAKTAENFNRLSVYTVSDLVGLYPRDYDVYHEPVFVKDISHESEHTEVAVE
CCCCCCCCCCCHHHCCCCEEEEEEHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCEEEEE
GQVCKSPDIYGSGRLKILTVTIKDYNGDSIKCSWYNMPFLKNTLRLGARYVFRGRLVNKR
CCCCCCCCCCCCCEEEEEEEEEEECCCCEEEEEEECCHHHHHHHHHHHHEEEECEEECCC
GWLLEQPKMYTLAQYKELQGTLQPIYPLTKGLTNNTVTKAVAQALEKYSAGLEKEYIPDY
CCEECCCCHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHH
IRKRYSLAEHNFSIVNIHFPKTMEEYVQARHRLAFEEFFLFTLATLSLKSANEHIPNSYV
HHHHHHHHHCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEE
IPESKEKDQFLESLSYSLTNAQLRTVSEVAQDMSGEHLCSRLIQGDVGSGKTVVATIALI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHH
NTVIAGYQGALMAPTEVLARQHYESFVKGFEKAGLDIRVELLVGSMTAKQKKEAYARIAD
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHCC
GTAGIIVGTHALIQEKVEYKELALVITDEQHRFGVNQRRDFSQKGKSPHILVMSATPIPR
CCCEEEECHHHHHHHHHCCEEEEEEEECCHHHCCCCCCCCHHHCCCCCEEEEEECCCCCC
TLAIILYGDLDISIIDEMPANRLPIKNCVVDESYRPKAYTFIHKQVASGRQCYVICPMVE
EEEEEEEECCCEEEECCCCCCCCCHHHEEECCCCCCCHHHHHHHHHHCCCEEEEEEEECC
DSEAVEAENVVDYTAMLKKELPDIRIEYLHGKMRPSLKNEVMERFAAHETDVLVSTTVIE
CCCHHHHHHHHHHHHHHHHCCCCCEEEEHHCCCCCHHHHHHHHHHHCCCCCEEEEEEEEE
VGVNVPNSTVMMVENSERFGLAQLHQLRGRVGRGEYQSYCIFVTGNKSEKIRKRLEILNK
EECCCCCCEEEEEECCCCCCHHHHHHHHCCCCCCCCCEEEEEEECCCHHHHHHHHHHHCC
SNDGFKIAEEDLRLRGPGDFFGVRQSGDFDFGIADVFTDAKTLKEASDAAKDMLKKDPEL
CCCCCEEECCCCEECCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
KLENNVYLKQKVAEYTIKCLEKINL
EECCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]