Click here to switch to the map view.

The map label for this gene is pyrH [H]

Identifier: 238916786

GI number: 238916786

Start: 860392

End: 861096

Strand: Direct

Name: pyrH [H]

Synonym: EUBELI_00848

Alternate gene names: 238916786

Gene position: 860392-861096 (Clockwise)

Preceding gene: 238916785

Following gene: 238916787

Centisome position: 40.13

GC content: 37.45

Gene sequence:

>705_bases
ATGGATAACATTAAAAGAGTAATACTTAAACTTAGCGGCGAGGCTCTTGCTAAGAAAGAGGGCGGCTACAATGATGAGCT
TATAGAGAATATTGCTAATCAGGTTAAGACAATAGTTGATAAAGGAACAGATGTTGGTGTAGTTATTGGTGGTGGTAACT
ACTGGAGAGGCCGTTCTAATGATAATATTGACAGAACTAAGGCTGACCAGATAGGTATGCTTGCAACAATTATGAACTGT
ATATATGTTTCAGAGATATTCCGTTCACAGGGACTTAAGACTAATATTCTTACACCATTCGAATGCGGAAGCATGACAAA
GCTTTTCTCTAAGGACAGAGCTAATAAGTATTTTGAGAAAGGCATGGTTGTATTCTTTGCAGGTGGAACTGGTCATCCAT
ATTTCTCAACAGATACAGGTATTGTATTGAGAGCTATTGAGCTTGATGCAGATGCTATTCTTCTTGCCAAGGCAATTGAT
GGAATATATGACAGTGATCCTAAGATTAACCCAGAGGCTAAGAAGTATGATACAATCTCAATCAACGAAGTTGTTGAGAA
GAAGCTTGGAGTTATTGATATGACAGCTTCTGTTATGTGTATGGAGAATAAGATGCCTCTTATGGTATTCGGACTCGAAG
AAGAGAACAGCATAGTTAATGCTTTATCAGGAAAGTTTAATGGAACAGTAGTAACTGTTGATTAA

Upstream 100 bases:

>100_bases
AGCAACAATTGACGGACGTTGCTCACAGTGTTATGCAGAAGTTAATATGGAAAGTATATTTGACATTAAAGGAAAAAAGA
ATAAATAACTGGAGGCACGT

Downstream 100 bases:

>100_bases
TATAATATTAATGGAGGATTTTATGGAAAATATTAAAGATATTGAAGGAAGAATGCAGAAGTCAGTTGACAACTTAAAGG
AAGAATATGTAACAATAAGA

Product: uridylate kinase

Products: NA

Alternate protein names: UK; Uridine monophosphate kinase; UMP kinase; UMPK [H]

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MDNIKRVILKLSGEALAKKEGGYNDELIENIANQVKTIVDKGTDVGVVIGGGNYWRGRSNDNIDRTKADQIGMLATIMNC
IYVSEIFRSQGLKTNILTPFECGSMTKLFSKDRANKYFEKGMVVFFAGGTGHPYFSTDTGIVLRAIELDADAILLAKAID
GIYDSDPKINPEAKKYDTISINEVVEKKLGVIDMTASVMCMENKMPLMVFGLEEENSIVNALSGKFNGTVVTVD

Sequences:

>Translated_234_residues
MDNIKRVILKLSGEALAKKEGGYNDELIENIANQVKTIVDKGTDVGVVIGGGNYWRGRSNDNIDRTKADQIGMLATIMNC
IYVSEIFRSQGLKTNILTPFECGSMTKLFSKDRANKYFEKGMVVFFAGGTGHPYFSTDTGIVLRAIELDADAILLAKAID
GIYDSDPKINPEAKKYDTISINEVVEKKLGVIDMTASVMCMENKMPLMVFGLEEENSIVNALSGKFNGTVVTVD
>Mature_234_residues
MDNIKRVILKLSGEALAKKEGGYNDELIENIANQVKTIVDKGTDVGVVIGGGNYWRGRSNDNIDRTKADQIGMLATIMNC
IYVSEIFRSQGLKTNILTPFECGSMTKLFSKDRANKYFEKGMVVFFAGGTGHPYFSTDTGIVLRAIELDADAILLAKAID
GIYDSDPKINPEAKKYDTISINEVVEKKLGVIDMTASVMCMENKMPLMVFGLEEENSIVNALSGKFNGTVVTVD

Specific function: Catalyzes the reversible phosphorylation of UMP to UDP [H]

COG id: COG0528

COG function: function code F; Uridylate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UMP kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786367, Length=231, Percent_Identity=34.1991341991342, Blast_Score=160, Evalue=9e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001048
- InterPro:   IPR011817
- InterPro:   IPR015963 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.4.22 [H]

Molecular weight: Translated: 25641; Mature: 25641

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNIKRVILKLSGEALAKKEGGYNDELIENIANQVKTIVDKGTDVGVVIGGGNYWRGRSN
CCHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCEECCCCC
DNIDRTKADQIGMLATIMNCIYVSEIFRSQGLKTNILTPFECGSMTKLFSKDRANKYFEK
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHC
GMVVFFAGGTGHPYFSTDTGIVLRAIELDADAILLAKAIDGIYDSDPKINPEAKKYDTIS
CEEEEEECCCCCCCEECCCCEEEEEEECCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCEE
INEVVEKKLGVIDMTASVMCMENKMPLMVFGLEEENSIVNALSGKFNGTVVTVD
HHHHHHHHCCEEEECCEEEEECCCCCEEEEECCCCCHHHHHHCCCCCCEEEEEC
>Mature Secondary Structure
MDNIKRVILKLSGEALAKKEGGYNDELIENIANQVKTIVDKGTDVGVVIGGGNYWRGRSN
CCHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCEECCCCC
DNIDRTKADQIGMLATIMNCIYVSEIFRSQGLKTNILTPFECGSMTKLFSKDRANKYFEK
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHC
GMVVFFAGGTGHPYFSTDTGIVLRAIELDADAILLAKAIDGIYDSDPKINPEAKKYDTIS
CEEEEEECCCCCCCEECCCCEEEEEEECCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCEE
INEVVEKKLGVIDMTASVMCMENKMPLMVFGLEEENSIVNALSGKFNGTVVTVD
HHHHHHHHCCEEEECCEEEEECCCCCEEEEECCCCCHHHHHHCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA