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The map label for this gene is vvpD [H]

Identifier: 238916730

GI number: 238916730

Start: 803922

End: 804692

Strand: Direct

Name: vvpD [H]

Synonym: EUBELI_00792

Alternate gene names: 238916730

Gene position: 803922-804692 (Clockwise)

Preceding gene: 238916729

Following gene: 238916731

Centisome position: 37.49

GC content: 36.96

Gene sequence:

>771_bases
ATGCAATACGAAATATTACTGTACTTCATTATCTTTCTATACGGTACCGTATTCGGAAGTTTTTTGAATGTACTGATTTA
CAGATTACCTTTAAAAGAGAATATAGCTACAGAACATTCGCATTGTATGACATGTGGCGAGAAAATCCAGTGGTATGATC
TCATACCACTGGTGAGCTACATAATATTAGGCGGAAAATGCAGACATTGTAAAGCAAAGATATCACCACAATATCCAATC
ATTGAAGCGACCAATGGAATAATGTATGTGATAGTCTTCTTGGTACACGGATTTAATCCGGTAAGTATTCTTATGTGTTT
TGCGTTTTCGATATTTCTTGTTATTTCAGTCATTGACTGGAGAACTTTCGAAATACCATTTTCACTAAATGTGGCAATTG
GTGTGCTGGGAGTTATAAGAATAATATTAGACCACAAGAACCTATTAGATTACCTAATAGGGTTTTGTGTTATAAGTGGA
TTTATGCTTGTCTGCTTATTTATTGGACGGGCAATTAAAGATATTGACGCATTTGGCGGTGGAGACATTAAGCTGATGGC
GTTTGCAGGATTATTCTTAGGATGGAAGTGCATAATCCTGGCATTTCTGATTGGCTGCATCTTAGGTGCAGTCATTCATT
CCATCCGTATGAAGGTTACGGATGCAGAGCATGTGCTTGCATTTGGACCATATTTGTGTGCAGGGCTTACGATAGCCATG
CTTTTTGGTACGAATATAATTAACTGTTATCTGTCATTAATGGGGTTTTAA

Upstream 100 bases:

>100_bases
ATCAGTAAAAGATGCATCAGGTGTAGTTACAGCTGCTAAGTCAAAGACGGCTATGGAAGTAAAATAATTTTGATACATAA
AACCTAAGGACCTAATAGTT

Downstream 100 bases:

>100_bases
TTGTTAAGATACCAATGATGGATACAGAAATTTATATATATTAAACTAGATTGATTAGCTTATTATGTGGGGAGCTGGAT
AGGAGGATTTATGGCTGCAG

Product: leader peptidase (prepilin peptidase) / N-methyltransferase

Products: NA

Alternate protein names: Leader peptidase; Prepilin peptidase; N-methyltransferase [H]

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MQYEILLYFIIFLYGTVFGSFLNVLIYRLPLKENIATEHSHCMTCGEKIQWYDLIPLVSYIILGGKCRHCKAKISPQYPI
IEATNGIMYVIVFLVHGFNPVSILMCFAFSIFLVISVIDWRTFEIPFSLNVAIGVLGVIRIILDHKNLLDYLIGFCVISG
FMLVCLFIGRAIKDIDAFGGGDIKLMAFAGLFLGWKCIILAFLIGCILGAVIHSIRMKVTDAEHVLAFGPYLCAGLTIAM
LFGTNIINCYLSLMGF

Sequences:

>Translated_256_residues
MQYEILLYFIIFLYGTVFGSFLNVLIYRLPLKENIATEHSHCMTCGEKIQWYDLIPLVSYIILGGKCRHCKAKISPQYPI
IEATNGIMYVIVFLVHGFNPVSILMCFAFSIFLVISVIDWRTFEIPFSLNVAIGVLGVIRIILDHKNLLDYLIGFCVISG
FMLVCLFIGRAIKDIDAFGGGDIKLMAFAGLFLGWKCIILAFLIGCILGAVIHSIRMKVTDAEHVLAFGPYLCAGLTIAM
LFGTNIINCYLSLMGF
>Mature_256_residues
MQYEILLYFIIFLYGTVFGSFLNVLIYRLPLKENIATEHSHCMTCGEKIQWYDLIPLVSYIILGGKCRHCKAKISPQYPI
IEATNGIMYVIVFLVHGFNPVSILMCFAFSIFLVISVIDWRTFEIPFSLNVAIGVLGVIRIILDHKNLLDYLIGFCVISG
FMLVCLFIGRAIKDIDAFGGGDIKLMAFAGLFLGWKCIILAFLIGCILGAVIHSIRMKVTDAEHVLAFGPYLCAGLTIAM
LFGTNIINCYLSLMGF

Specific function: Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue [H]

COG id: COG1989

COG function: function code NOU; Type II secretory pathway, prepilin signal peptidase PulO and related peptidases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A24 family [H]

Homologues:

Organism=Escherichia coli, GI87082194, Length=257, Percent_Identity=27.6264591439689, Blast_Score=75, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010627
- InterPro:   IPR014032
- InterPro:   IPR000045 [H]

Pfam domain/function: PF06750 DiS_P_DiS; PF01478 Peptidase_A24 [H]

EC number: =3.4.23.43 [H]

Molecular weight: Translated: 28623; Mature: 28623

Theoretical pI: Translated: 7.64; Mature: 7.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
7.8 %Cys+Met (Translated Protein)
4.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
7.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHCC
>Mature Secondary Structure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HHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9826339 [H]