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The map label for this gene is pilC [H]

Identifier: 238916728

GI number: 238916728

Start: 802062

End: 803339

Strand: Direct

Name: pilC [H]

Synonym: EUBELI_00790

Alternate gene names: 238916728

Gene position: 802062-803339 (Clockwise)

Preceding gene: 238916726

Following gene: 238916729

Centisome position: 37.41

GC content: 36.85

Gene sequence:

>1278_bases
ATGTGTTATACTAATAGCACAATTCAGGATATAAATCCAAGTAATGATGAGGAGAGAGGTATGGAGAGTTTTTCATACAA
AGCGGTTAGCGCTGCGGGAAAAGATGTTAAAGGCTCAGTTGAGGCTGAAAGCCGAGAAGAAGCTGCCAGAAAGATTAAGG
AACAAGGCTTGGTTCCAGTATCAATCGGCAAGCAGGGAGCACTTGATAAAGATGTTAATATTCCTATATTTAAAGGGAAA
AAGATACCTGCAAGAGACATGAGTGTATTCTGTAGACAGTTTGCAAGTATATTGAAGGCTGGTGTAAGTGTTATCAATGC
GTTGGAGATGCTTGCAGAACAGACGGAGAATAAAAAATTAAAAGAAGCAATTGTTAATACACAGTCTAATGTAGAAAAAG
GTGAGAATTTATCTGATTCTATGAGACAGAATGATGCATTCCCAAGTATTCTTATAGATATGGTAAGAGCTGGCGAGGCA
TCAGGTAGTCTGGAGAATTCTCTTACACGAATGGCTATACAGTTTGAAAAGGATGCCAAGCTTAACGGAATAGTTAAGAA
AGCAATGATGTATCCTATAGTTCTTTTATGCGTAATGATTGGCGTAATTATAGTAATGCTTACATTCGTTATTCCAAGCT
TTATGACAATGTTCGAGGATCTTGACAGTGAGCTTCCGGTTACTACAAAAGCAATTCTTGCTATGAGTAACAGCTTAAAG
AGTTACTGGTATATATACATAATTGTTGTAGTTGGAATAGTTGTAGGTATACAGATGTACAAGCGTACAGATAATGGAAA
ACACAACCTTGATAAACTTAAGCTTAAAATACCAGTATTTGGATTATTACAGACTAAGTCAGCTTGTGCTTCATTTGCAA
GAACAATGAGCACACTTCTTCAGGCAGGTATGCCAATGATTGATGCACTTGAAATATCTGCATCAACTATGAAGAATGTT
TTGTTTTATGATGGCTTAGAAAAGGCTAAGAATGGAGTTTCACTCGGACTGCCTCTTTCAAACCAGTTAAAAGCAACGGG
ATTATTCCCGGCAATGGTTGTACATATGGTAGGTATCGGCGAAGAAACTGGTAATGTTGAAGAAATGCTTACTAATTCAG
CTGCATATTATGAGGAAGAAGTAGAAGTTCAGACACAGACACTTACATCACTTATGGAACCTATTATAATCGTTCTTATG
GCATTGGTAGTTGTAATGCTTATAATGGCAATATATCAGCCTATGATTCAGCTTTATAATACATTGGGAAATGCATAA

Upstream 100 bases:

>100_bases
TGTGGTGTTTAATAAGAATGCATGATATAGATATAAAGTACTATAAATAGACATATTATTTTTTGTTTATTTTGGTAAAA
ATATTGTGAACAAATTATGA

Downstream 100 bases:

>100_bases
TTTTATTAATGTATATAATTTGCTATGCATGTCGCAGTTTATGATAGCAAGTTTATATAAATATATTTCAAAAGGGAGAT
ATGAAACATGAAAAAGACAC

Product: type IV pilus assembly protein PilC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 425; Mature: 425

Protein sequence:

>425_residues
MCYTNSTIQDINPSNDEERGMESFSYKAVSAAGKDVKGSVEAESREEAARKIKEQGLVPVSIGKQGALDKDVNIPIFKGK
KIPARDMSVFCRQFASILKAGVSVINALEMLAEQTENKKLKEAIVNTQSNVEKGENLSDSMRQNDAFPSILIDMVRAGEA
SGSLENSLTRMAIQFEKDAKLNGIVKKAMMYPIVLLCVMIGVIIVMLTFVIPSFMTMFEDLDSELPVTTKAILAMSNSLK
SYWYIYIIVVVGIVVGIQMYKRTDNGKHNLDKLKLKIPVFGLLQTKSACASFARTMSTLLQAGMPMIDALEISASTMKNV
LFYDGLEKAKNGVSLGLPLSNQLKATGLFPAMVVHMVGIGEETGNVEEMLTNSAAYYEEEVEVQTQTLTSLMEPIIIVLM
ALVVVMLIMAIYQPMIQLYNTLGNA

Sequences:

>Translated_425_residues
MCYTNSTIQDINPSNDEERGMESFSYKAVSAAGKDVKGSVEAESREEAARKIKEQGLVPVSIGKQGALDKDVNIPIFKGK
KIPARDMSVFCRQFASILKAGVSVINALEMLAEQTENKKLKEAIVNTQSNVEKGENLSDSMRQNDAFPSILIDMVRAGEA
SGSLENSLTRMAIQFEKDAKLNGIVKKAMMYPIVLLCVMIGVIIVMLTFVIPSFMTMFEDLDSELPVTTKAILAMSNSLK
SYWYIYIIVVVGIVVGIQMYKRTDNGKHNLDKLKLKIPVFGLLQTKSACASFARTMSTLLQAGMPMIDALEISASTMKNV
LFYDGLEKAKNGVSLGLPLSNQLKATGLFPAMVVHMVGIGEETGNVEEMLTNSAAYYEEEVEVQTQTLTSLMEPIIIVLM
ALVVVMLIMAIYQPMIQLYNTLGNA
>Mature_425_residues
MCYTNSTIQDINPSNDEERGMESFSYKAVSAAGKDVKGSVEAESREEAARKIKEQGLVPVSIGKQGALDKDVNIPIFKGK
KIPARDMSVFCRQFASILKAGVSVINALEMLAEQTENKKLKEAIVNTQSNVEKGENLSDSMRQNDAFPSILIDMVRAGEA
SGSLENSLTRMAIQFEKDAKLNGIVKKAMMYPIVLLCVMIGVIIVMLTFVIPSFMTMFEDLDSELPVTTKAILAMSNSLK
SYWYIYIIVVVGIVVGIQMYKRTDNGKHNLDKLKLKIPVFGLLQTKSACASFARTMSTLLQAGMPMIDALEISASTMKNV
LFYDGLEKAKNGVSLGLPLSNQLKATGLFPAMVVHMVGIGEETGNVEEMLTNSAAYYEEEVEVQTQTLTSLMEPIIIVLM
ALVVVMLIMAIYQPMIQLYNTLGNA

Specific function: Involved in the translocation of the type IV pilin (pilA) [H]

COG id: COG1459

COG function: function code NU; Type II secretory pathway, component PulF

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP F family [H]

Homologues:

Organism=Escherichia coli, GI1789724, Length=397, Percent_Identity=26.7002518891688, Blast_Score=194, Evalue=8e-51,
Organism=Escherichia coli, GI1786295, Length=398, Percent_Identity=25.3768844221106, Blast_Score=145, Evalue=4e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003004
- InterPro:   IPR018076
- InterPro:   IPR001992 [H]

Pfam domain/function: PF00482 GSPII_F [H]

EC number: NA

Molecular weight: Translated: 46624; Mature: 46624

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
6.4 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
6.4 %Met     (Mature Protein)
7.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCYTNSTIQDINPSNDEERGMESFSYKAVSAAGKDVKGSVEAESREEAARKIKEQGLVPV
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCEE
SIGKQGALDKDVNIPIFKGKKIPARDMSVFCRQFASILKAGVSVINALEMLAEQTENKKL
ECCCCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KEAIVNTQSNVEKGENLSDSMRQNDAFPSILIDMVRAGEASGSLENSLTRMAIQFEKDAK
HHHHHCCHHHHHCCCCHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCH
LNGIVKKAMMYPIVLLCVMIGVIIVMLTFVIPSFMTMFEDLDSELPVTTKAILAMSNSLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
SYWYIYIIVVVGIVVGIQMYKRTDNGKHNLDKLKLKIPVFGLLQTKSACASFARTMSTLL
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHEEEECCHHHHHHHHHHHHHHHHHHHHHH
QAGMPMIDALEISASTMKNVLFYDGLEKAKNGVSLGLPLSNQLKATGLFPAMVVHMVGIG
HCCCCHHHHHHHHHHHHHHHHHHCCHHHHCCCCEECCCCCCCHHHHHHHHHHHHHHHHCC
EETGNVEEMLTNSAAYYEEEVEVQTQTLTSLMEPIIIVLMALVVVMLIMAIYQPMIQLYN
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLGNA
HHCCC
>Mature Secondary Structure
MCYTNSTIQDINPSNDEERGMESFSYKAVSAAGKDVKGSVEAESREEAARKIKEQGLVPV
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCEE
SIGKQGALDKDVNIPIFKGKKIPARDMSVFCRQFASILKAGVSVINALEMLAEQTENKKL
ECCCCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KEAIVNTQSNVEKGENLSDSMRQNDAFPSILIDMVRAGEASGSLENSLTRMAIQFEKDAK
HHHHHCCHHHHHCCCCHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCH
LNGIVKKAMMYPIVLLCVMIGVIIVMLTFVIPSFMTMFEDLDSELPVTTKAILAMSNSLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
SYWYIYIIVVVGIVVGIQMYKRTDNGKHNLDKLKLKIPVFGLLQTKSACASFARTMSTLL
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHEEEECCHHHHHHHHHHHHHHHHHHHHHH
QAGMPMIDALEISASTMKNVLFYDGLEKAKNGVSLGLPLSNQLKATGLFPAMVVHMVGIG
HCCCCHHHHHHHHHHHHHHHHHHCCHHHHCCCCEECCCCCCCHHHHHHHHHHHHHHHHCC
EETGNVEEMLTNSAAYYEEEVEVQTQTLTSLMEPIIIVLMALVVVMLIMAIYQPMIQLYN
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLGNA
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1971619; 10984043 [H]