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The map label for this gene is clpB [H]

Identifier: 238916634

GI number: 238916634

Start: 691897

End: 694359

Strand: Direct

Name: clpB [H]

Synonym: EUBELI_00691

Alternate gene names: 238916634

Gene position: 691897-694359 (Clockwise)

Preceding gene: 238916633

Following gene: 238916635

Centisome position: 32.27

GC content: 39.87

Gene sequence:

>2463_bases
ATGCAGAGCAGATTTACCAGCAAAGCGCAGGAGGCACTTAATTATGCGGCAGATACAGCGGCTATGTTAGGTCATGGTTA
TATAGGTTCAGAGCATCTTCTTATAGGACTTATCAAAGCGGAGGGCGGACTTGCATCTTCAGTTCTTCTTAGCAATGATA
TTACGGATGAGAAGATAATTAATCTTGTTTGCCAGCTTATAGCACCAGATAGTGTAGTTAATGTTAAAGAACCATCAGGA
TATACTCCAAGGGTTAGACATATACTCGACAATGCAGCACGAGAGGCAGCAAGATTTAAGTCAGAGCTTATAGGAACAGA
ACACATTTTAATAGCAATAATAAAAGAAACAGACAGCGTAGCTTCAAGGCTTCTTAATACTATAGGGGTTCCTGTCAAGA
AGATGTATGTTGATCTTCTTATGGCTATGGGAGAAGATGCCGGCAGGGTTAAAGAAGATTTCCAGAATGGAAGACCAAGA
GGAAATGATAAAAAAAGCACAGCAACTCTTGACCAGTACAGCAGGGATCTTACACAGATGGCAAGAGAAGGCAGATTGGA
CCCTGTTATTGGCAGGGAAGAAGAGATTCAGAGGGTTATTCAGATATTGAGCAGAAGAACTAAGAATAATCCTTGCCTTA
TAGGTGAACCGGGAGTTGGTAAGACTGCCATAGCAGAAGGACTTGCAGCCAGAATAGTTGAAGGAAATGTGCCTGAGACA
ATTAAGGACAAGCGTCTTCTGACATTAGATTTGTCAGGTATGGTTGCCGGTTCTAAGTACAGGGGTGAATTTGAGGAAAG
AATCAAGAAGGTAATAGCAGAGGTTAAAAATGCTGGAAATGTATTACTTTTTCTGGATGAGATTCACACAATAATAGGTG
CAGGAGGAGCAGAGGGAGCAATAGATGCGTCTAATATATTAAAACCATCTCTTGCAAGAGGAGAAATCCAGCTTATTGGT
GCTACAACTCTTGAGGAGTATAGAAAACATATTGAGAAGGATGCTGCTCTTGAGAGAAGATTCCAGCCTGTTAAGGTTGA
AGAACCTACGGCAGAAGAGGCAATTCAGATATTAAGAGGCCTTAAGGGCAGGTATGAAGAGCATCATCATGTTACAATTA
CAGATGAGGCAGTAGTTGCAGCTGTTAAGTTATCTAAGAGATATATCAATGACAGATTCCTTCCTGATAAGGCTATTGAT
CTTATTGATGAAGCATCTTCTAAGACAAGGCTTGATGCATATGTAATGCCTGATGAGATTAAGACATTAGAGGCACAGAT
AGAACAGCTTACCAAGGATAAGGAAGAAGCAATAAAGTCAGAAGCTTATGAGCAGGCTGGTGAAATTAAGAAGAAACAGT
TAAAGAAAAAAGAACAGCTTGAAAAGATGACAAAGCAGTGGCAGGATAGTATCAATAAGAATAATCTTATTGTCGATGAA
GATGAGATTGCTTCTGTTGTATCGACATGGACAAAGATTCCTGTACAGAGAATTGCACAGGCAGAGTCTGAGCGTCTTAT
GAAACTGGAAGAAACTTTACACAACAGGGTTATAGGACAGGACGAGGCTGTTGCAGCTGTTGCTAAGGCAATACGAAGAG
GAAGAGTGGGACTTAAAGATCCTGACAGACCAATTGGCTCATTCCTTTTCTTAGGACCTACAGGTGTTGGAAAAACAGAA
CTTTCAAAGGCACTGGCAGATGCAATGTTTGGTACAGAGAATTCTCTTATAAGAGTTGATATGTCAGAATTTATGGAGAA
GCATACAGTGTCAAAGCTTATAGGTTCACCTCCAGGATATGTAGGATATGATGAGGGAGGACAGCTTAGTGAGAAAGTAA
GAAGAAATCCATACTCTGTAATTCTTTTTGATGAAGTTGAGAAAGCTCACCCGGATGTATTTAATGTACTTTTACAGGTG
CTTGACGACGGGCATATCACTGATTCAACAGGCAGAGTTATAGATTTCAAGAATACTATAATTATAATGACTAGCAATGC
TGGAGCTGAAAATATTGTATCGCCTAAATCACTGGGATTCTCGTCAGGAATGACTGAGCAGCAGAATCATGAGGAGATGA
AGGGCAAGGTTATGGACGAGGTTAAGAGAATATTCAAGCCAGAATTCATTAACCGAATAGATGATATAGTTGTATTCCAT
GTTCTTGGAAAAGAGCAGATAGCACAGATTGTCGATATAATGATTGCCAATGTCAATAAGCGTATTATGGAACAGATGAA
ATTATCAATAGAGCTTGATGATGCAGCTAGACAGTGGCTTGTCGATAAGGGTTATGATTCTAAATATGGTGCAAGACCAT
TACGCCGTACAATCCAGAATGAGGTTGAAGATGTTCTTGCAGAGCGGATTCTTATGGGAAAAGTCCACGCTGGCAATAAA
GTGAAGATAACTGTAAAGGACAATAAGCTTAACTTTACTCTCAAGAGAGGAATGAATAAATAA

Upstream 100 bases:

>100_bases
AGAGGAACTGGAAGTGTCACGAGCTGATTTTATAAGAGAACATCTTCCAACAATACATTAACAGATATTTACGAAATCAA
TCATAGAAAGGGTTATAGAT

Downstream 100 bases:

>100_bases
ATTAATAAATAAACAATAAACAACTGACAAATTGCTGGCGCTTTTTGTCAGTTTATTGTATAATCAGTACATACATATCG
TAACATATAGGAGGATAATA

Product: ATP-dependent Clp protease ATP-binding subunit ClpC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 820; Mature: 820

Protein sequence:

>820_residues
MQSRFTSKAQEALNYAADTAAMLGHGYIGSEHLLIGLIKAEGGLASSVLLSNDITDEKIINLVCQLIAPDSVVNVKEPSG
YTPRVRHILDNAAREAARFKSELIGTEHILIAIIKETDSVASRLLNTIGVPVKKMYVDLLMAMGEDAGRVKEDFQNGRPR
GNDKKSTATLDQYSRDLTQMAREGRLDPVIGREEEIQRVIQILSRRTKNNPCLIGEPGVGKTAIAEGLAARIVEGNVPET
IKDKRLLTLDLSGMVAGSKYRGEFEERIKKVIAEVKNAGNVLLFLDEIHTIIGAGGAEGAIDASNILKPSLARGEIQLIG
ATTLEEYRKHIEKDAALERRFQPVKVEEPTAEEAIQILRGLKGRYEEHHHVTITDEAVVAAVKLSKRYINDRFLPDKAID
LIDEASSKTRLDAYVMPDEIKTLEAQIEQLTKDKEEAIKSEAYEQAGEIKKKQLKKKEQLEKMTKQWQDSINKNNLIVDE
DEIASVVSTWTKIPVQRIAQAESERLMKLEETLHNRVIGQDEAVAAVAKAIRRGRVGLKDPDRPIGSFLFLGPTGVGKTE
LSKALADAMFGTENSLIRVDMSEFMEKHTVSKLIGSPPGYVGYDEGGQLSEKVRRNPYSVILFDEVEKAHPDVFNVLLQV
LDDGHITDSTGRVIDFKNTIIIMTSNAGAENIVSPKSLGFSSGMTEQQNHEEMKGKVMDEVKRIFKPEFINRIDDIVVFH
VLGKEQIAQIVDIMIANVNKRIMEQMKLSIELDDAARQWLVDKGYDSKYGARPLRRTIQNEVEDVLAERILMGKVHAGNK
VKITVKDNKLNFTLKRGMNK

Sequences:

>Translated_820_residues
MQSRFTSKAQEALNYAADTAAMLGHGYIGSEHLLIGLIKAEGGLASSVLLSNDITDEKIINLVCQLIAPDSVVNVKEPSG
YTPRVRHILDNAAREAARFKSELIGTEHILIAIIKETDSVASRLLNTIGVPVKKMYVDLLMAMGEDAGRVKEDFQNGRPR
GNDKKSTATLDQYSRDLTQMAREGRLDPVIGREEEIQRVIQILSRRTKNNPCLIGEPGVGKTAIAEGLAARIVEGNVPET
IKDKRLLTLDLSGMVAGSKYRGEFEERIKKVIAEVKNAGNVLLFLDEIHTIIGAGGAEGAIDASNILKPSLARGEIQLIG
ATTLEEYRKHIEKDAALERRFQPVKVEEPTAEEAIQILRGLKGRYEEHHHVTITDEAVVAAVKLSKRYINDRFLPDKAID
LIDEASSKTRLDAYVMPDEIKTLEAQIEQLTKDKEEAIKSEAYEQAGEIKKKQLKKKEQLEKMTKQWQDSINKNNLIVDE
DEIASVVSTWTKIPVQRIAQAESERLMKLEETLHNRVIGQDEAVAAVAKAIRRGRVGLKDPDRPIGSFLFLGPTGVGKTE
LSKALADAMFGTENSLIRVDMSEFMEKHTVSKLIGSPPGYVGYDEGGQLSEKVRRNPYSVILFDEVEKAHPDVFNVLLQV
LDDGHITDSTGRVIDFKNTIIIMTSNAGAENIVSPKSLGFSSGMTEQQNHEEMKGKVMDEVKRIFKPEFINRIDDIVVFH
VLGKEQIAQIVDIMIANVNKRIMEQMKLSIELDDAARQWLVDKGYDSKYGARPLRRTIQNEVEDVLAERILMGKVHAGNK
VKITVKDNKLNFTLKRGMNK
>Mature_820_residues
MQSRFTSKAQEALNYAADTAAMLGHGYIGSEHLLIGLIKAEGGLASSVLLSNDITDEKIINLVCQLIAPDSVVNVKEPSG
YTPRVRHILDNAAREAARFKSELIGTEHILIAIIKETDSVASRLLNTIGVPVKKMYVDLLMAMGEDAGRVKEDFQNGRPR
GNDKKSTATLDQYSRDLTQMAREGRLDPVIGREEEIQRVIQILSRRTKNNPCLIGEPGVGKTAIAEGLAARIVEGNVPET
IKDKRLLTLDLSGMVAGSKYRGEFEERIKKVIAEVKNAGNVLLFLDEIHTIIGAGGAEGAIDASNILKPSLARGEIQLIG
ATTLEEYRKHIEKDAALERRFQPVKVEEPTAEEAIQILRGLKGRYEEHHHVTITDEAVVAAVKLSKRYINDRFLPDKAID
LIDEASSKTRLDAYVMPDEIKTLEAQIEQLTKDKEEAIKSEAYEQAGEIKKKQLKKKEQLEKMTKQWQDSINKNNLIVDE
DEIASVVSTWTKIPVQRIAQAESERLMKLEETLHNRVIGQDEAVAAVAKAIRRGRVGLKDPDRPIGSFLFLGPTGVGKTE
LSKALADAMFGTENSLIRVDMSEFMEKHTVSKLIGSPPGYVGYDEGGQLSEKVRRNPYSVILFDEVEKAHPDVFNVLLQV
LDDGHITDSTGRVIDFKNTIIIMTSNAGAENIVSPKSLGFSSGMTEQQNHEEMKGKVMDEVKRIFKPEFINRIDDIVVFH
VLGKEQIAQIVDIMIANVNKRIMEQMKLSIELDDAARQWLVDKGYDSKYGARPLRRTIQNEVEDVLAERILMGKVHAGNK
VKITVKDNKLNFTLKRGMNK

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=328, Percent_Identity=37.5, Blast_Score=209, Evalue=1e-53,
Organism=Escherichia coli, GI1788943, Length=889, Percent_Identity=46.5691788526434, Blast_Score=717, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=814, Percent_Identity=39.4348894348894, Blast_Score=553, Evalue=1e-158,
Organism=Saccharomyces cerevisiae, GI6320464, Length=724, Percent_Identity=44.6132596685083, Blast_Score=558, Evalue=1e-159,
Organism=Saccharomyces cerevisiae, GI6323002, Length=889, Percent_Identity=37.6827896512936, Blast_Score=545, Evalue=1e-155,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150
- InterPro:   IPR001943 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small; PF02151 UVR [H]

EC number: NA

Molecular weight: Translated: 91275; Mature: 91275

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSRFTSKAQEALNYAADTAAMLGHGYIGSEHLLIGLIKAEGGLASSVLLSNDITDEKII
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCHHHHHHCCCCCHHHHH
NLVCQLIAPDSVVNVKEPSGYTPRVRHILDNAAREAARFKSELIGTEHILIAIIKETDSV
HHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHH
ASRLLNTIGVPVKKMYVDLLMAMGEDAGRVKEDFQNGRPRGNDKKSTATLDQYSRDLTQM
HHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
AREGRLDPVIGREEEIQRVIQILSRRTKNNPCLIGEPGVGKTAIAEGLAARIVEGNVPET
HHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHHHCCCCCCC
IKDKRLLTLDLSGMVAGSKYRGEFEERIKKVIAEVKNAGNVLLFLDEIHTIIGAGGAEGA
CCCCEEEEEECCCCCCCCHHCCHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCCC
IDASNILKPSLARGEIQLIGATTLEEYRKHIEKDAALERRFQPVKVEEPTAEEAIQILRG
CCHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
LKGRYEEHHHVTITDEAVVAAVKLSKRYINDRFLPDKAIDLIDEASSKTRLDAYVMPDEI
HHCCCCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCEEEEECCHHH
KTLEAQIEQLTKDKEEAIKSEAYEQAGEIKKKQLKKKEQLEKMTKQWQDSINKNNLIVDE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECH
DEIASVVSTWTKIPVQRIAQAESERLMKLEETLHNRVIGQDEAVAAVAKAIRRGRVGLKD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCC
PDRPIGSFLFLGPTGVGKTELSKALADAMFGTENSLIRVDMSEFMEKHTVSKLIGSPPGY
CCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHCCCCCC
VGYDEGGQLSEKVRRNPYSVILFDEVEKAHPDVFNVLLQVLDDGHITDSTGRVIDFKNTI
CCCCCCCHHHHHHHCCCCEEEEECCHHHHCCHHHHHHHHHHCCCCEECCCCCEEEECCEE
IIMTSNAGAENIVSPKSLGFSSGMTEQQNHEEMKGKVMDEVKRIFKPEFINRIDDIVVFH
EEEECCCCCCCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
VLGKEQIAQIVDIMIANVNKRIMEQMKLSIELDDAARQWLVDKGYDSKYGARPLRRTIQN
HHCHHHHHHHHHHHHHHHHHHHHHHHHHHEEECHHHHHHHHCCCCCCCCCCHHHHHHHHH
EVEDVLAERILMGKVHAGNKVKITVKDNKLNFTLKRGMNK
HHHHHHHHHHHHHCCCCCCEEEEEEECCCEEEECCCCCCC
>Mature Secondary Structure
MQSRFTSKAQEALNYAADTAAMLGHGYIGSEHLLIGLIKAEGGLASSVLLSNDITDEKII
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCHHHHHHCCCCCHHHHH
NLVCQLIAPDSVVNVKEPSGYTPRVRHILDNAAREAARFKSELIGTEHILIAIIKETDSV
HHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHH
ASRLLNTIGVPVKKMYVDLLMAMGEDAGRVKEDFQNGRPRGNDKKSTATLDQYSRDLTQM
HHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
AREGRLDPVIGREEEIQRVIQILSRRTKNNPCLIGEPGVGKTAIAEGLAARIVEGNVPET
HHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHHHCCCCCCC
IKDKRLLTLDLSGMVAGSKYRGEFEERIKKVIAEVKNAGNVLLFLDEIHTIIGAGGAEGA
CCCCEEEEEECCCCCCCCHHCCHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCCC
IDASNILKPSLARGEIQLIGATTLEEYRKHIEKDAALERRFQPVKVEEPTAEEAIQILRG
CCHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
LKGRYEEHHHVTITDEAVVAAVKLSKRYINDRFLPDKAIDLIDEASSKTRLDAYVMPDEI
HHCCCCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCEEEEECCHHH
KTLEAQIEQLTKDKEEAIKSEAYEQAGEIKKKQLKKKEQLEKMTKQWQDSINKNNLIVDE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECH
DEIASVVSTWTKIPVQRIAQAESERLMKLEETLHNRVIGQDEAVAAVAKAIRRGRVGLKD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCC
PDRPIGSFLFLGPTGVGKTELSKALADAMFGTENSLIRVDMSEFMEKHTVSKLIGSPPGY
CCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHCCCCCC
VGYDEGGQLSEKVRRNPYSVILFDEVEKAHPDVFNVLLQVLDDGHITDSTGRVIDFKNTI
CCCCCCCHHHHHHHCCCCEEEEECCHHHHCCHHHHHHHHHHCCCCEECCCCCEEEECCEE
IIMTSNAGAENIVSPKSLGFSSGMTEQQNHEEMKGKVMDEVKRIFKPEFINRIDDIVVFH
EEEECCCCCCCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
VLGKEQIAQIVDIMIANVNKRIMEQMKLSIELDDAARQWLVDKGYDSKYGARPLRRTIQN
HHCHHHHHHHHHHHHHHHHHHHHHHHHHHEEECHHHHHHHHCCCCCCCCCCHHHHHHHHH
EVEDVLAERILMGKVHAGNKVKITVKDNKLNFTLKRGMNK
HHHHHHHHHHHHHCCCCCCEEEEEEECCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]