Click here to switch to the map view.

The map label for this gene is trxA [H]

Identifier: 238916584

GI number: 238916584

Start: 647645

End: 647962

Strand: Direct

Name: trxA [H]

Synonym: EUBELI_00641

Alternate gene names: 238916584

Gene position: 647645-647962 (Clockwise)

Preceding gene: 238916583

Following gene: 238916585

Centisome position: 30.2

GC content: 39.94

Gene sequence:

>318_bases
ATGGCAGCCAGAGCTAATGCAGAGAATTTCGAAGAACTGGTTCTTAAGTCAGAACTTCCGGTTCTTGTGGATTTCTATTC
AGATTCATGCATCCCATGCAAGATGATGGCAGGGGTTGTAGGAGACATTGAAGATGATTACGAGGGAAAGCTTAATGTTT
ACAAGGTAAATGTAAACTTTGATGAATCGCTTGCTTCTAAATATGAAGTATTGGCAGCACCTACATTTGTTGCATTCAAC
AAAGGTGCTGAGACAGGCAGAATTGCAGGAAAGACAACTAAGGATGCACTGCTTGGATTATTTGAAGGATTAGTATAA

Upstream 100 bases:

>100_bases
AAGAGGGACATCAGATATTAAAGCTTACAGCTAATGAGGATGGTACATATACTCTTATCGTTAGAAAGGTAGAAGACGAG
GATTAAGGAAAGGAGGGCTT

Downstream 100 bases:

>100_bases
TAAACGGCGCAAGAAATGAGATTTAATTAAAGGGAGGAATGTTATGAAGATTACAGTTGCAGGAAACAAGAAGGAATATG
AAGATGGAATTACAGTAGCA

Product: thioredoxin 1

Products: NA

Alternate protein names: Trx [H]

Number of amino acids: Translated: 105; Mature: 104

Protein sequence:

>105_residues
MAARANAENFEELVLKSELPVLVDFYSDSCIPCKMMAGVVGDIEDDYEGKLNVYKVNVNFDESLASKYEVLAAPTFVAFN
KGAETGRIAGKTTKDALLGLFEGLV

Sequences:

>Translated_105_residues
MAARANAENFEELVLKSELPVLVDFYSDSCIPCKMMAGVVGDIEDDYEGKLNVYKVNVNFDESLASKYEVLAAPTFVAFN
KGAETGRIAGKTTKDALLGLFEGLV
>Mature_104_residues
AARANAENFEELVLKSELPVLVDFYSDSCIPCKMMAGVVGDIEDDYEGKLNVYKVNVNFDESLASKYEVLAAPTFVAFNK
GAETGRIAGKTTKDALLGLFEGLV

Specific function: Component of the thioredoxin-thioredoxin reductase system. Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI87082331, Length=90, Percent_Identity=36.6666666666667, Blast_Score=71, Evalue=1e-14,
Organism=Escherichia coli, GI1788936, Length=90, Percent_Identity=31.1111111111111, Blast_Score=59, Evalue=5e-11,

Paralogues:

None

Copy number: 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00085 Thioredoxin [H]

EC number: NA

Molecular weight: Translated: 11388; Mature: 11257

Theoretical pI: Translated: 4.20; Mature: 4.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAARANAENFEELVLKSELPVLVDFYSDSCIPCKMMAGVVGDIEDDYEGKLNVYKVNVNF
CCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHCCCCCCCCCCEEEEEEECCC
DESLASKYEVLAAPTFVAFNKGAETGRIAGKTTKDALLGLFEGLV
CHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
AARANAENFEELVLKSELPVLVDFYSDSCIPCKMMAGVVGDIEDDYEGKLNVYKVNVNF
CCCCCCHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHCCCCCCCCCCEEEEEEECCC
DESLASKYEVLAAPTFVAFNKGAETGRIAGKTTKDALLGLFEGLV
CHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Reduction reactions; participates in dithiol-disulfide exchange reactions [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA