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The map label for this gene is iscR [H]

Identifier: 238916580

GI number: 238916580

Start: 644669

End: 645100

Strand: Direct

Name: iscR [H]

Synonym: EUBELI_00637

Alternate gene names: 238916580

Gene position: 644669-645100 (Clockwise)

Preceding gene: 238916579

Following gene: 238916581

Centisome position: 30.07

GC content: 38.66

Gene sequence:

>432_bases
ATGAAGATTTCAACAAAGGGAAGATATGCGCTCAGGGTCATGATTGATCTTGCAGAGCATAATACAGGAGAATATATTCC
ACTTATGGATATTGCCAGAAGACAGGATATTTCTGAGAAGTATCTGGAAGCGATTGTTGCAACATTAAGCAAGAATGATT
TTCTCATATCATTAAGAGGAAAGGGTGGCGGATACAAGCTTGCACGCAATCCGGAGGATTATTCAGTGCTTAGCATACTT
CTTGTAACAGAGGGTTCACTTGCACCGGTAGCATGTCTTGAGAAGAAGCCTAACAGATGTCCGAAGGTGGCAGAATGTAA
GACTTTACAGATGTGGGAAAACTTTGAGAAGCTTGTTAATGATTACTTCAGCAATATTACAATAGCAGATTTGGTTAATT
CTAATGTGGGAATAGACAGTTATATTATATAG

Upstream 100 bases:

>100_bases
GCTAAATAAATTCATTTAACACTTGAAAAATATACAAACATTGTGGTAAAGTATGTTTAACATACAGTATTAATGTGTTA
TTAGAAAAGAGGTTATATAT

Downstream 100 bases:

>100_bases
TAAATGTTAATGATAGTTCATGACTGCCTGAGATTGTTCAGGCAGTTATATTTTTTCTCAAATAACCTATTGACATACTA
GGTAAAAGGGTTTAATATAT

Product: cysteine desulfurase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 143; Mature: 143

Protein sequence:

>143_residues
MKISTKGRYALRVMIDLAEHNTGEYIPLMDIARRQDISEKYLEAIVATLSKNDFLISLRGKGGGYKLARNPEDYSVLSIL
LVTEGSLAPVACLEKKPNRCPKVAECKTLQMWENFEKLVNDYFSNITIADLVNSNVGIDSYII

Sequences:

>Translated_143_residues
MKISTKGRYALRVMIDLAEHNTGEYIPLMDIARRQDISEKYLEAIVATLSKNDFLISLRGKGGGYKLARNPEDYSVLSIL
LVTEGSLAPVACLEKKPNRCPKVAECKTLQMWENFEKLVNDYFSNITIADLVNSNVGIDSYII
>Mature_143_residues
MKISTKGRYALRVMIDLAEHNTGEYIPLMDIARRQDISEKYLEAIVATLSKNDFLISLRGKGGGYKLARNPEDYSVLSIL
LVTEGSLAPVACLEKKPNRCPKVAECKTLQMWENFEKLVNDYFSNITIADLVNSNVGIDSYII

Specific function: Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins [H]

COG id: COG1959

COG function: function code K; Predicted transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH rrf2-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788880, Length=139, Percent_Identity=32.3741007194245, Blast_Score=83, Evalue=6e-18,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010242
- InterPro:   IPR000944
- InterPro:   IPR011991 [H]

Pfam domain/function: PF02082 Rrf2 [H]

EC number: NA

Molecular weight: Translated: 16062; Mature: 16062

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKISTKGRYALRVMIDLAEHNTGEYIPLMDIARRQDISEKYLEAIVATLSKNDFLISLRG
CCCCCCCCEEEEEEEECCCCCCCCEECHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEEEC
KGGGYKLARNPEDYSVLSILLVTEGSLAPVACLEKKPNRCPKVAECKTLQMWENFEKLVN
CCCCEECCCCCCCHHEEEEEEECCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH
DYFSNITIADLVNSNVGIDSYII
HHHCCCCHHHHHCCCCCCCEECC
>Mature Secondary Structure
MKISTKGRYALRVMIDLAEHNTGEYIPLMDIARRQDISEKYLEAIVATLSKNDFLISLRG
CCCCCCCCEEEEEEEECCCCCCCCEECHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEEEC
KGGGYKLARNPEDYSVLSILLVTEGSLAPVACLEKKPNRCPKVAECKTLQMWENFEKLVN
CCCCEECCCCCCCHHEEEEEEECCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH
DYFSNITIADLVNSNVGIDSYII
HHHCCCCHHHHHCCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA