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The map label for this gene is yhdR [H]

Identifier: 238916571

GI number: 238916571

Start: 637239

End: 638426

Strand: Direct

Name: yhdR [H]

Synonym: EUBELI_00628

Alternate gene names: 238916571

Gene position: 637239-638426 (Clockwise)

Preceding gene: 238916568

Following gene: 238916572

Centisome position: 29.72

GC content: 38.22

Gene sequence:

>1188_bases
ATGATAGCTGATTCAATGGTTTCTTTAGTAAAAAACAGTTCGGTAATCCGTGCAATGTTCGAGGAAGGCAACAGACTTGC
CAAGTTATACGGAGCAGAGAATGTGTATGATTTCTCACTTGGTAATCCGAATGTTCCAGCACCTGCAGAGGTTAATGAAG
CGGTTAAGGATATAGTAGATAATGAAGAATCAACATTTATACATGGCTATATGAGTAATGCAGGATATGAGGATGTGAGA
CAGACTATAGCTGAGTCACTTAATAGAAGATTCGGAACACATTTTAACCATACTAATATTGTAATGACTGTTGGAGCAGC
AGGCGGGCTTAATACAATATTCAAGACATTACTTAATCCGGGCGAAGAGGTTATGACATTTGCGCCATTCTTTGGTGAAT
ACAGGAATTATGTAAGCAATTTTGGCGGAAAATTAGTGGTTGTTTCACCTAATACTGTGGATTTCCAGCCTAAGCTTGAC
GAGTTTGAAGCAAAGATAACACCTAAGACAAGAGCTGTTATCGTTAATAATCCTAATAACCCGACAGGTGTTGTATATTC
AGAGGATACTATAAAGAAGATGGCTGCTATTATGGATAAGAAGCAGAAGGAGTACGGAACAGAGATTTACTTAATAGCAG
ATGAACCATACAGAGAGTTAGCTTATGACGGTGTTGATGTTCCATATCTTACTAAATATTACGACAATACTATTGTTGGT
TATTCATACAGTAAGTCGCTTTCACTTCCAGGTGAGCGAATCGGATATCTTGTTATTCCTGATGAGGTTACAGATTCAGA
AGATGTTAAGTCAGCAGCTTCTGTAGCTACAAGAATTTTAGGATTCGTTAATGCGCCTTCACTTATGCAGAGAGTTGTTG
CAAAATGTGTTGATGCACAGGTTAATCTTGAGGCATATGACAAGAACAGAAAGGCAATATACGAAGGACTCACAAAGTTA
GGCTTTGAGTGTGTAAAGCCAGAGGGTGCTTTCTATCTTTTCGTAAAGTCACCTGTTGAAGATGAAACTGTTTTCTGTGA
GGCAGCCAAGAAACACAATATCCTTATGGTTCCTGCGTCATCATTTGGATGCCCTGGATATGTTAGAATTGCATACTGTG
TATCTTACGATACAATTGTTAATTCATTACCACATTTTGCAGAAGTTGCTAAAGAGATGGGATTATAA

Upstream 100 bases:

>100_bases
ACTATTATAAATAATAGCATATGATTGAATGTATTGAAAGTTGTAAAATCAAATGATTTTGATTATAATGTAGTCATATT
TTTTTTGGAGGATATAAACA

Downstream 100 bases:

>100_bases
TTATTCGTGAAAGAAGAGGACTTATATATGAAGACATGGGAGAAGAATATCAGAAGAGTTGAGCCATATGTGCCGGGAGA
GCAGCCTAAGGTTAAAGATG

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MIADSMVSLVKNSSVIRAMFEEGNRLAKLYGAENVYDFSLGNPNVPAPAEVNEAVKDIVDNEESTFIHGYMSNAGYEDVR
QTIAESLNRRFGTHFNHTNIVMTVGAAGGLNTIFKTLLNPGEEVMTFAPFFGEYRNYVSNFGGKLVVVSPNTVDFQPKLD
EFEAKITPKTRAVIVNNPNNPTGVVYSEDTIKKMAAIMDKKQKEYGTEIYLIADEPYRELAYDGVDVPYLTKYYDNTIVG
YSYSKSLSLPGERIGYLVIPDEVTDSEDVKSAASVATRILGFVNAPSLMQRVVAKCVDAQVNLEAYDKNRKAIYEGLTKL
GFECVKPEGAFYLFVKSPVEDETVFCEAAKKHNILMVPASSFGCPGYVRIAYCVSYDTIVNSLPHFAEVAKEMGL

Sequences:

>Translated_395_residues
MIADSMVSLVKNSSVIRAMFEEGNRLAKLYGAENVYDFSLGNPNVPAPAEVNEAVKDIVDNEESTFIHGYMSNAGYEDVR
QTIAESLNRRFGTHFNHTNIVMTVGAAGGLNTIFKTLLNPGEEVMTFAPFFGEYRNYVSNFGGKLVVVSPNTVDFQPKLD
EFEAKITPKTRAVIVNNPNNPTGVVYSEDTIKKMAAIMDKKQKEYGTEIYLIADEPYRELAYDGVDVPYLTKYYDNTIVG
YSYSKSLSLPGERIGYLVIPDEVTDSEDVKSAASVATRILGFVNAPSLMQRVVAKCVDAQVNLEAYDKNRKAIYEGLTKL
GFECVKPEGAFYLFVKSPVEDETVFCEAAKKHNILMVPASSFGCPGYVRIAYCVSYDTIVNSLPHFAEVAKEMGL
>Mature_395_residues
MIADSMVSLVKNSSVIRAMFEEGNRLAKLYGAENVYDFSLGNPNVPAPAEVNEAVKDIVDNEESTFIHGYMSNAGYEDVR
QTIAESLNRRFGTHFNHTNIVMTVGAAGGLNTIFKTLLNPGEEVMTFAPFFGEYRNYVSNFGGKLVVVSPNTVDFQPKLD
EFEAKITPKTRAVIVNNPNNPTGVVYSEDTIKKMAAIMDKKQKEYGTEIYLIADEPYRELAYDGVDVPYLTKYYDNTIVG
YSYSKSLSLPGERIGYLVIPDEVTDSEDVKSAASVATRILGFVNAPSLMQRVVAKCVDAQVNLEAYDKNRKAIYEGLTKL
GFECVKPEGAFYLFVKSPVEDETVFCEAAKKHNILMVPASSFGCPGYVRIAYCVSYDTIVNSLPHFAEVAKEMGL

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=335, Percent_Identity=24.4776119402985, Blast_Score=109, Evalue=5e-24,
Organism=Homo sapiens, GI169881279, Length=335, Percent_Identity=24.4776119402985, Blast_Score=109, Evalue=5e-24,
Organism=Homo sapiens, GI4507369, Length=404, Percent_Identity=25.2475247524752, Blast_Score=102, Evalue=9e-22,
Organism=Homo sapiens, GI56713254, Length=376, Percent_Identity=21.8085106382979, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI56713256, Length=376, Percent_Identity=21.8085106382979, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI169881281, Length=236, Percent_Identity=23.728813559322, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1788627, Length=387, Percent_Identity=24.8062015503876, Blast_Score=108, Evalue=7e-25,
Organism=Escherichia coli, GI1786816, Length=357, Percent_Identity=24.6498599439776, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1788722, Length=391, Percent_Identity=23.5294117647059, Blast_Score=88, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17567369, Length=324, Percent_Identity=25.9259259259259, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17567663, Length=365, Percent_Identity=25.2054794520548, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI71994472, Length=240, Percent_Identity=28.75, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71994476, Length=240, Percent_Identity=28.75, Blast_Score=90, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6322401, Length=307, Percent_Identity=26.0586319218241, Blast_Score=94, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6320317, Length=376, Percent_Identity=24.7340425531915, Blast_Score=70, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6323118, Length=306, Percent_Identity=25.1633986928105, Blast_Score=66, Evalue=8e-12,
Organism=Drosophila melanogaster, GI18859735, Length=377, Percent_Identity=25.4641909814324, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI28573069, Length=339, Percent_Identity=23.8938053097345, Blast_Score=88, Evalue=8e-18,
Organism=Drosophila melanogaster, GI24646114, Length=339, Percent_Identity=23.8938053097345, Blast_Score=88, Evalue=8e-18,
Organism=Drosophila melanogaster, GI28573067, Length=339, Percent_Identity=23.8938053097345, Blast_Score=88, Evalue=8e-18,
Organism=Drosophila melanogaster, GI28573065, Length=339, Percent_Identity=23.8938053097345, Blast_Score=88, Evalue=8e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43712; Mature: 43712

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIADSMVSLVKNSSVIRAMFEEGNRLAKLYGAENVYDFSLGNPNVPAPAEVNEAVKDIVD
CCHHHHHHHHHCCHHHHHHHHCCCCEEEEECCCCEEEEECCCCCCCCCHHHHHHHHHHHC
NEESTFIHGYMSNAGYEDVRQTIAESLNRRFGTHFNHTNIVMTVGAAGGLNTIFKTLLNP
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHCC
GEEVMTFAPFFGEYRNYVSNFGGKLVVVSPNTVDFQPKLDEFEAKITPKTRAVIVNNPNN
CHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEECCCCHHHHCEEECCCEEEEEEECCCC
PTGVVYSEDTIKKMAAIMDKKQKEYGTEIYLIADEPYRELAYDGVDVPYLTKYYDNTIVG
CCEEEECHHHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHCCCCCCCHHHHHHCCEEEE
YSYSKSLSLPGERIGYLVIPDEVTDSEDVKSAASVATRILGFVNAPSLMQRVVAKCVDAQ
EECCCCCCCCHHHEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCC
VNLEAYDKNRKAIYEGLTKLGFECVKPEGAFYLFVKSPVEDETVFCEAAKKHNILMVPAS
CEEHHHCCCHHHHHHHHHHCCCEEECCCCCEEEEEECCCCCCCEEEEHHCCCCEEEEECC
SFGCPGYVRIAYCVSYDTIVNSLPHFAEVAKEMGL
CCCCCCEEEEEEEEEHHHHHHCCHHHHHHHHHHCC
>Mature Secondary Structure
MIADSMVSLVKNSSVIRAMFEEGNRLAKLYGAENVYDFSLGNPNVPAPAEVNEAVKDIVD
CCHHHHHHHHHCCHHHHHHHHCCCCEEEEECCCCEEEEECCCCCCCCCHHHHHHHHHHHC
NEESTFIHGYMSNAGYEDVRQTIAESLNRRFGTHFNHTNIVMTVGAAGGLNTIFKTLLNP
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHCC
GEEVMTFAPFFGEYRNYVSNFGGKLVVVSPNTVDFQPKLDEFEAKITPKTRAVIVNNPNN
CHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEECCCCHHHHCEEECCCEEEEEEECCCC
PTGVVYSEDTIKKMAAIMDKKQKEYGTEIYLIADEPYRELAYDGVDVPYLTKYYDNTIVG
CCEEEECHHHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHCCCCCCCHHHHHHCCEEEE
YSYSKSLSLPGERIGYLVIPDEVTDSEDVKSAASVATRILGFVNAPSLMQRVVAKCVDAQ
EECCCCCCCCHHHEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCC
VNLEAYDKNRKAIYEGLTKLGFECVKPEGAFYLFVKSPVEDETVFCEAAKKHNILMVPAS
CEEHHHCCCHHHHHHHHHHCCCEEECCCCCEEEEEECCCCCCCEEEEHHCCCCEEEEECC
SFGCPGYVRIAYCVSYDTIVNSLPHFAEVAKEMGL
CCCCCCEEEEEEEEEHHHHHHCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]