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The map label for this gene is yerI [H]

Identifier: 238916526

GI number: 238916526

Start: 596665

End: 597660

Strand: Direct

Name: yerI [H]

Synonym: EUBELI_00583

Alternate gene names: 238916526

Gene position: 596665-597660 (Clockwise)

Preceding gene: 238916525

Following gene: 238916527

Centisome position: 27.83

GC content: 41.27

Gene sequence:

>996_bases
ATGGCATTTGAAAATGTTGATTTATTTGATGCGGTTGCAAATGCTTCGCTTGAAAAATACGGATGGCAGGACAGATGTGA
GGCGAAACTCATAGTGCTGTCGGAGAATGCAACCTATATGGTCAAGAACAAAGAAACAGGTGAAAAAGAGGGAGTGCTTA
GAATAAGCAGACCGGGTTATCACACATTGGATGAGCTTAATTCAGAGATGAAGTGGTTAAGACAGATTAATGACTACACA
CCGCTTCTTGTAGCTAATCCTATAAAAGGGCTTGATGGTAAGAATATACAGGAGATTACAGGACCGGATGGAAATGTATA
TTTCTGCGTTATATGTGATTTTCTTCCGGGAGAAGCACCTGATGAGAATAACGAGGAGCAGATGGTAAAGCAGTTCAGAT
ATCTCGGCGAGACAACAGCTTATCTTCACCGTCAGACAGAGATATGGAACGGAACAGACAAGCTTGACCGTATGGTATGG
ACTTACGACACGATAATAGGTGAACATGCTGCATGGGGTGACTGGAGAGCATTTCCAGAGATGACCCCGGAGGCAGAAAA
TATATTGTCAGAGGTTTCAAGAATTATTAAGAGAAGACTTGAAAGATATGGAACTAATGAGAATAATTTTGGACTCATAC
ATGCAGATTTAAGATTAGCTAATCTGCTTATTGAGGGCGACCAGATTAAGGTTATTGATTTTGATGACTGCGGTTTTGGA
TGGCACTTACATGACCTTGCGTCAGCGCTTAGTTTTATTGAGGACAAGCCAATTGTTCCAAAGCTTGTAAATGCATGGCT
TGCAGGATATAAGAAGGTTCTTCCGTTCACTGATACGGATTTTGAAGAAATAGACACATTTATAATGATGAGAAGATTAC
AGCTTACTGCATGGCTTGCATCTCATCAGGAATCAGGTCCGGTAGCAGAATTAAGTGTCGGCTGGATGGACGGAACCATG
GAATTAGCCGAAAGGTATCTTAGATTATTTGGCTAG

Upstream 100 bases:

>100_bases
AACAACATCTATGGGACAGTAATTAAATATAAGAAAAGTACAAAGGCGTACATGAATCGGATAGATTTGTGTACGCCTTT
TCTGATTGGAGGATAATGAC

Downstream 100 bases:

>100_bases
GCACATAAGAAATCTTCGTGACAACAAATCATGAACAACAATAAGGGAGGAAGCTATTATGGGCGAAAAGAAAACAAATG
CATTATCTAAATCAATGAAG

Product: homoserine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 331; Mature: 330

Protein sequence:

>331_residues
MAFENVDLFDAVANASLEKYGWQDRCEAKLIVLSENATYMVKNKETGEKEGVLRISRPGYHTLDELNSEMKWLRQINDYT
PLLVANPIKGLDGKNIQEITGPDGNVYFCVICDFLPGEAPDENNEEQMVKQFRYLGETTAYLHRQTEIWNGTDKLDRMVW
TYDTIIGEHAAWGDWRAFPEMTPEAENILSEVSRIIKRRLERYGTNENNFGLIHADLRLANLLIEGDQIKVIDFDDCGFG
WHLHDLASALSFIEDKPIVPKLVNAWLAGYKKVLPFTDTDFEEIDTFIMMRRLQLTAWLASHQESGPVAELSVGWMDGTM
ELAERYLRLFG

Sequences:

>Translated_331_residues
MAFENVDLFDAVANASLEKYGWQDRCEAKLIVLSENATYMVKNKETGEKEGVLRISRPGYHTLDELNSEMKWLRQINDYT
PLLVANPIKGLDGKNIQEITGPDGNVYFCVICDFLPGEAPDENNEEQMVKQFRYLGETTAYLHRQTEIWNGTDKLDRMVW
TYDTIIGEHAAWGDWRAFPEMTPEAENILSEVSRIIKRRLERYGTNENNFGLIHADLRLANLLIEGDQIKVIDFDDCGFG
WHLHDLASALSFIEDKPIVPKLVNAWLAGYKKVLPFTDTDFEEIDTFIMMRRLQLTAWLASHQESGPVAELSVGWMDGTM
ELAERYLRLFG
>Mature_330_residues
AFENVDLFDAVANASLEKYGWQDRCEAKLIVLSENATYMVKNKETGEKEGVLRISRPGYHTLDELNSEMKWLRQINDYTP
LLVANPIKGLDGKNIQEITGPDGNVYFCVICDFLPGEAPDENNEEQMVKQFRYLGETTAYLHRQTEIWNGTDKLDRMVWT
YDTIIGEHAAWGDWRAFPEMTPEAENILSEVSRIIKRRLERYGTNENNFGLIHADLRLANLLIEGDQIKVIDFDDCGFGW
HLHDLASALSFIEDKPIVPKLVNAWLAGYKKVLPFTDTDFEEIDTFIMMRRLQLTAWLASHQESGPVAELSVGWMDGTME
LAERYLRLFG

Specific function: Unknown

COG id: COG2334

COG function: function code R; Putative homoserine kinase type II (protein kinase fold)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pseudomonas-type thrB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002575
- InterPro:   IPR011009 [H]

Pfam domain/function: PF01636 APH [H]

EC number: NA

Molecular weight: Translated: 38010; Mature: 37879

Theoretical pI: Translated: 4.45; Mature: 4.45

Prosite motif: PS00109 PROTEIN_KINASE_TYR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFENVDLFDAVANASLEKYGWQDRCEAKLIVLSENATYMVKNKETGEKEGVLRISRPGY
CCCCCCHHHHHHHHCHHHHCCCCCCCCEEEEEEECCCEEEEECCCCCCCCCEEEECCCCC
HTLDELNSEMKWLRQINDYTPLLVANPIKGLDGKNIQEITGPDGNVYFCVICDFLPGEAP
CCHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCC
DENNEEQMVKQFRYLGETTAYLHRQTEIWNGTDKLDRMVWTYDTIIGEHAAWGDWRAFPE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
MTPEAENILSEVSRIIKRRLERYGTNENNFGLIHADLRLANLLIEGDQIKVIDFDDCGFG
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHEEEHHEEECCEEEEEEECCCCCC
WHLHDLASALSFIEDKPIVPKLVNAWLAGYKKVLPFTDTDFEEIDTFIMMRRLQLTAWLA
CCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
SHQESGPVAELSVGWMDGTMELAERYLRLFG
HCCCCCCEEEEEECCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
AFENVDLFDAVANASLEKYGWQDRCEAKLIVLSENATYMVKNKETGEKEGVLRISRPGY
CCCCCHHHHHHHHCHHHHCCCCCCCCEEEEEEECCCEEEEECCCCCCCCCEEEECCCCC
HTLDELNSEMKWLRQINDYTPLLVANPIKGLDGKNIQEITGPDGNVYFCVICDFLPGEAP
CCHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCC
DENNEEQMVKQFRYLGETTAYLHRQTEIWNGTDKLDRMVWTYDTIIGEHAAWGDWRAFPE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
MTPEAENILSEVSRIIKRRLERYGTNENNFGLIHADLRLANLLIEGDQIKVIDFDDCGFG
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHEEEHHEEECCEEEEEEECCCCCC
WHLHDLASALSFIEDKPIVPKLVNAWLAGYKKVLPFTDTDFEEIDTFIMMRRLQLTAWLA
CCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
SHQESGPVAELSVGWMDGTMELAERYLRLFG
HCCCCCCEEEEEECCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9701819; 9384377 [H]