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The map label for this gene is yciR [C]

Identifier: 238916473

GI number: 238916473

Start: 535572

End: 537743

Strand: Direct

Name: yciR [C]

Synonym: EUBELI_00530

Alternate gene names: 238916473

Gene position: 535572-537743 (Clockwise)

Preceding gene: 238916471

Following gene: 238916474

Centisome position: 24.98

GC content: 35.91

Gene sequence:

>2172_bases
ATGATAGGCTATAATATTATCAGATTTATGTATTATCGGAGGGTTATTTTGAGCGGGAATAAAACAGTTAATTTGGAATT
GTCACAGATTATACATATGTTAGAAGATAATGGAACATTTGTAGAGGTTTCAAAGAACATAATTGAGAAAATAACGGATA
ATCTTCATGCACAGGATGCTGTTATTATGCAGATAAGTGCTGATGGAAAAAGTATGCATGCTATAGCAGAGGCTAAAGAT
GTAATAGGTAGTAAGCTGGATGTTGAAGATATCAGTCAGTGTTGTCTGTGTTCAGACGAATTAAAGAGAACTGCAATGAG
CACAGCATCTGATGAAGAGAAGGAAAGACTTGCATTGTGTAATGCAAAGATTTGTATATCTGTTCCTATTACAATTAATA
ATGTTAAGGCAATGTATCTTCTTGTTATGGGGGATACAGATGATTTTGCAGGCGAAGATAAGGTTATTGAATACATAAAA
GATGTCGCAATGATTATACATAGTATTGCACAAAGCAAGGTTATCAATAATTCGCTTATATCATCTTATGATGTATTACA
GAAAATTCTTGATAATATTGGTTCTGGAATTATTGTATGCAGTAAGAATTCGGGAAATATTCTTTTTGAAAATGATATGG
CAAGTCATGTTACTGAAGTACGGGAGACAATAAGAGAGTGTTTAGAGGAAGTATTTCAGAATAAGGATATATCAGGTCAT
ATAGGAACACCGATGGAACGGTATAATACCGAATCTGGTCTGTGGTTTGAAGTCAGATTTTCAGAGCTGAAGTGGATTGA
CGGAAGTGATGTTGTTGTGGCAACAGCAGCAGATATTACACAGAAAAAGAAGAATCAGCAGAAGATAGAATATCAGGCAC
ATAATGATTTCCTGACAGGTCTGTATAACCGTATGAAATGTGAAGTGGATTTAAGAAAGGTTATAAGAAGAACAGAGAAA
GCCGGACTTAAGGGTGCTGTACTGTTTCTTGACCTTGATGATTTCAAGCATATTAATGACGGTCTTGGACATCAGTATGG
AGATATCCTGTTACAGCAGATAGCTGCGGGACTTACAGGTATTCCGGGACTCAGGGGACATTGTTACAGAATGGGTGGAG
ATGAATTTGTAATAATCATTGAGCCTGAAATATATAATGAACTTAGTAAAATAGTCACTAACATAAAGACACTGTTTAAT
AAGCCGTGGTATCTTATGGAAACTGAGTATTTCTGTACTATGAGTATGGGTATTGCGTTGTTCCCGGATAATAGTGTTGA
TGTCCATGAGATAACAAGAATGGCTGATGTTGCAATGTATGAAGCAAAGCGTTCAGGAAAGAACGGATATGCCTATTACA
GCAGCGAGGTTGAGAATTCGACAGCCAAGAGACTTGATATTGAGAACAATATGAGACAGGCTATTTCAAATGAAATCAAT
GAATTTGTGGTATTTTATCAGCCGGTTGTCAATGTCAATACACAAATGTGTACATCATGTGAGGCACTTGTAAGATGGGA
CAGCAAGGCGCTTGGATTTATGGGGCCGGGTGAATTTATTCCACTTGCGGAATATCTGGGACTTATTACATCAATTGGTG
ACTATGTTCTTGAAGAAGCATGCAGAAGATGTAAGATATGGAATGACAATGGACATCCTGATTTTTACATTAATGTTAAT
CTGTCAGTAGTACAGCTTTTACAGAAGGATGTTGTCGAGAATATTAAAAGGATTCTTGATAAGACAGGAGTTAATCCTAA
GAATATAGTACTTGAGATTACAGAATCATTTGCAATCAATGATATGCAGAGAGTTATGGAGATTATCACAGGACTTAAGA
AGTTAGGACCTAGAATTGCACTTGATGATTTTGGAACAGGATATTCTTCACTTAATTACATAAAGCAGCTTCCTCTTGAT
ATCATTAAGGTTGATAAAACATTTATTGATGATATTGTTGAAGATGATTATGCACAGGCATTTGTTAAGCTTATAGTTGA
CCTTTCCAAGACTATTGGTACTAAGATAGTTGTTGAGGGTGTTGAACATAAGGAACAGTTTGAACTGCTTAAAAGTCTTG
GTGTGGATTATATACAGGGATATTACTTTGGAAAGCCTGTTCCAGCCAATATTTTTGAAGAGAAAAACTTAGAGGGGAGA
TTGGGCAAATGA

Upstream 100 bases:

>100_bases
ATAACACCCTCTGGAATATAAAACAATTAATTATCTGTGAAATTGAAAATATGGGTGTTTATGTATAAATGATTTTAAAA
AATCAGTTTCCAAAAGCTTT

Downstream 100 bases:

>100_bases
ACATACTGATTAAAGAAGGCAGGGTGCTTGACCCTGCAAGTAAGACGGACAAAGTGATGGACGTGCTTATTAAGGACGGA
TTTATTGCGGCTATGGAAGA

Product: histidine ammonia-lyase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 723; Mature: 723

Protein sequence:

>723_residues
MIGYNIIRFMYYRRVILSGNKTVNLELSQIIHMLEDNGTFVEVSKNIIEKITDNLHAQDAVIMQISADGKSMHAIAEAKD
VIGSKLDVEDISQCCLCSDELKRTAMSTASDEEKERLALCNAKICISVPITINNVKAMYLLVMGDTDDFAGEDKVIEYIK
DVAMIIHSIAQSKVINNSLISSYDVLQKILDNIGSGIIVCSKNSGNILFENDMASHVTEVRETIRECLEEVFQNKDISGH
IGTPMERYNTESGLWFEVRFSELKWIDGSDVVVATAADITQKKKNQQKIEYQAHNDFLTGLYNRMKCEVDLRKVIRRTEK
AGLKGAVLFLDLDDFKHINDGLGHQYGDILLQQIAAGLTGIPGLRGHCYRMGGDEFVIIIEPEIYNELSKIVTNIKTLFN
KPWYLMETEYFCTMSMGIALFPDNSVDVHEITRMADVAMYEAKRSGKNGYAYYSSEVENSTAKRLDIENNMRQAISNEIN
EFVVFYQPVVNVNTQMCTSCEALVRWDSKALGFMGPGEFIPLAEYLGLITSIGDYVLEEACRRCKIWNDNGHPDFYINVN
LSVVQLLQKDVVENIKRILDKTGVNPKNIVLEITESFAINDMQRVMEIITGLKKLGPRIALDDFGTGYSSLNYIKQLPLD
IIKVDKTFIDDIVEDDYAQAFVKLIVDLSKTIGTKIVVEGVEHKEQFELLKSLGVDYIQGYYFGKPVPANIFEEKNLEGR
LGK

Sequences:

>Translated_723_residues
MIGYNIIRFMYYRRVILSGNKTVNLELSQIIHMLEDNGTFVEVSKNIIEKITDNLHAQDAVIMQISADGKSMHAIAEAKD
VIGSKLDVEDISQCCLCSDELKRTAMSTASDEEKERLALCNAKICISVPITINNVKAMYLLVMGDTDDFAGEDKVIEYIK
DVAMIIHSIAQSKVINNSLISSYDVLQKILDNIGSGIIVCSKNSGNILFENDMASHVTEVRETIRECLEEVFQNKDISGH
IGTPMERYNTESGLWFEVRFSELKWIDGSDVVVATAADITQKKKNQQKIEYQAHNDFLTGLYNRMKCEVDLRKVIRRTEK
AGLKGAVLFLDLDDFKHINDGLGHQYGDILLQQIAAGLTGIPGLRGHCYRMGGDEFVIIIEPEIYNELSKIVTNIKTLFN
KPWYLMETEYFCTMSMGIALFPDNSVDVHEITRMADVAMYEAKRSGKNGYAYYSSEVENSTAKRLDIENNMRQAISNEIN
EFVVFYQPVVNVNTQMCTSCEALVRWDSKALGFMGPGEFIPLAEYLGLITSIGDYVLEEACRRCKIWNDNGHPDFYINVN
LSVVQLLQKDVVENIKRILDKTGVNPKNIVLEITESFAINDMQRVMEIITGLKKLGPRIALDDFGTGYSSLNYIKQLPLD
IIKVDKTFIDDIVEDDYAQAFVKLIVDLSKTIGTKIVVEGVEHKEQFELLKSLGVDYIQGYYFGKPVPANIFEEKNLEGR
LGK
>Mature_723_residues
MIGYNIIRFMYYRRVILSGNKTVNLELSQIIHMLEDNGTFVEVSKNIIEKITDNLHAQDAVIMQISADGKSMHAIAEAKD
VIGSKLDVEDISQCCLCSDELKRTAMSTASDEEKERLALCNAKICISVPITINNVKAMYLLVMGDTDDFAGEDKVIEYIK
DVAMIIHSIAQSKVINNSLISSYDVLQKILDNIGSGIIVCSKNSGNILFENDMASHVTEVRETIRECLEEVFQNKDISGH
IGTPMERYNTESGLWFEVRFSELKWIDGSDVVVATAADITQKKKNQQKIEYQAHNDFLTGLYNRMKCEVDLRKVIRRTEK
AGLKGAVLFLDLDDFKHINDGLGHQYGDILLQQIAAGLTGIPGLRGHCYRMGGDEFVIIIEPEIYNELSKIVTNIKTLFN
KPWYLMETEYFCTMSMGIALFPDNSVDVHEITRMADVAMYEAKRSGKNGYAYYSSEVENSTAKRLDIENNMRQAISNEIN
EFVVFYQPVVNVNTQMCTSCEALVRWDSKALGFMGPGEFIPLAEYLGLITSIGDYVLEEACRRCKIWNDNGHPDFYINVN
LSVVQLLQKDVVENIKRILDKTGVNPKNIVLEITESFAINDMQRVMEIITGLKKLGPRIALDDFGTGYSSLNYIKQLPLD
IIKVDKTFIDDIVEDDYAQAFVKLIVDLSKTIGTKIVVEGVEHKEQFELLKSLGVDYIQGYYFGKPVPANIFEEKNLEGR
LGK

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=443, Percent_Identity=32.2799097065463, Blast_Score=260, Evalue=2e-70,
Organism=Escherichia coli, GI87081921, Length=442, Percent_Identity=28.5067873303167, Blast_Score=206, Evalue=4e-54,
Organism=Escherichia coli, GI226510982, Length=307, Percent_Identity=31.5960912052117, Blast_Score=177, Evalue=2e-45,
Organism=Escherichia coli, GI1790496, Length=253, Percent_Identity=33.9920948616601, Blast_Score=170, Evalue=3e-43,
Organism=Escherichia coli, GI87081845, Length=240, Percent_Identity=35.4166666666667, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI1786507, Length=242, Percent_Identity=35.5371900826446, Blast_Score=145, Evalue=1e-35,
Organism=Escherichia coli, GI87081743, Length=246, Percent_Identity=33.739837398374, Blast_Score=141, Evalue=1e-34,
Organism=Escherichia coli, GI87082096, Length=257, Percent_Identity=35.0194552529183, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI87081980, Length=250, Percent_Identity=30.8, Blast_Score=134, Evalue=3e-32,
Organism=Escherichia coli, GI1787055, Length=403, Percent_Identity=29.7766749379653, Blast_Score=131, Evalue=2e-31,
Organism=Escherichia coli, GI1788849, Length=262, Percent_Identity=30.5343511450382, Blast_Score=122, Evalue=9e-29,
Organism=Escherichia coli, GI1788502, Length=249, Percent_Identity=30.1204819277108, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1788381, Length=575, Percent_Identity=23.8260869565217, Blast_Score=105, Evalue=7e-24,
Organism=Escherichia coli, GI1788956, Length=164, Percent_Identity=34.7560975609756, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI145693134, Length=155, Percent_Identity=30.3225806451613, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI87081881, Length=197, Percent_Identity=29.4416243654822, Blast_Score=77, Evalue=5e-15,
Organism=Escherichia coli, GI87082007, Length=168, Percent_Identity=31.547619047619, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI87081977, Length=169, Percent_Identity=28.4023668639053, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1787410, Length=168, Percent_Identity=26.7857142857143, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI1787816, Length=155, Percent_Identity=32.9032258064516, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI1786584, Length=175, Percent_Identity=26.8571428571429, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1787262, Length=213, Percent_Identity=29.1079812206573, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1787802, Length=170, Percent_Identity=28.2352941176471, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 81584; Mature: 81584

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGYNIIRFMYYRRVILSGNKTVNLELSQIIHMLEDNGTFVEVSKNIIEKITDNLHAQDA
CCCHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHCCCCEEEHHHHHHHHHHHCCCCCCE
VIMQISADGKSMHAIAEAKDVIGSKLDVEDISQCCLCSDELKRTAMSTASDEEKERLALC
EEEEEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCHHHHHHHHHHCCCCHHHHHHHHC
NAKICISVPITINNVKAMYLLVMGDTDDFAGEDKVIEYIKDVAMIIHSIAQSKVINNSLI
CCEEEEEEEEEEECCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SSYDVLQKILDNIGSGIIVCSKNSGNILFENDMASHVTEVRETIRECLEEVFQNKDISGH
HHHHHHHHHHHHCCCCEEEEECCCCCEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
IGTPMERYNTESGLWFEVRFSELKWIDGSDVVVATAADITQKKKNQQKIEYQAHNDFLTG
CCCCHHHCCCCCCCEEEEEECEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
LYNRMKCEVDLRKVIRRTEKAGLKGAVLFLDLDDFKHINDGLGHQYGDILLQQIAAGLTG
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECHHHHHHHHHCCHHHHHHHHHHHHHCCCC
IPGLRGHCYRMGGDEFVIIIEPEIYNELSKIVTNIKTLFNKPWYLMETEYFCTMSMGIAL
CCCCCCEEEEECCCEEEEEECCHHHHHHHHHHHHHHHHHCCCEEEEECCEEEEEECCEEE
FPDNSVDVHEITRMADVAMYEAKRSGKNGYAYYSSEVENSTAKRLDIENNMRQAISNEIN
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEECCHHCCCHHHHCCHHHHHHHHHHHHHH
EFVVFYQPVVNVNTQMCTSCEALVRWDSKALGFMGPGEFIPLAEYLGLITSIGDYVLEEA
HEEEEEEHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
CRRCKIWNDNGHPDFYINVNLSVVQLLQKDVVENIKRILDKTGVNPKNIVLEITESFAIN
HHHCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHH
DMQRVMEIITGLKKLGPRIALDDFGTGYSSLNYIKQLPLDIIKVDKTFIDDIVEDDYAQA
HHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHH
FVKLIVDLSKTIGTKIVVEGVEHKEQFELLKSLGVDYIQGYYFGKPVPANIFEEKNLEGR
HHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHCHHHHCCEECCCCCCCCHHHCCCCCCC
LGK
CCC
>Mature Secondary Structure
MIGYNIIRFMYYRRVILSGNKTVNLELSQIIHMLEDNGTFVEVSKNIIEKITDNLHAQDA
CCCHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHCCCCEEEHHHHHHHHHHHCCCCCCE
VIMQISADGKSMHAIAEAKDVIGSKLDVEDISQCCLCSDELKRTAMSTASDEEKERLALC
EEEEEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCHHHHHHHHHHCCCCHHHHHHHHC
NAKICISVPITINNVKAMYLLVMGDTDDFAGEDKVIEYIKDVAMIIHSIAQSKVINNSLI
CCEEEEEEEEEEECCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SSYDVLQKILDNIGSGIIVCSKNSGNILFENDMASHVTEVRETIRECLEEVFQNKDISGH
HHHHHHHHHHHHCCCCEEEEECCCCCEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
IGTPMERYNTESGLWFEVRFSELKWIDGSDVVVATAADITQKKKNQQKIEYQAHNDFLTG
CCCCHHHCCCCCCCEEEEEECEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
LYNRMKCEVDLRKVIRRTEKAGLKGAVLFLDLDDFKHINDGLGHQYGDILLQQIAAGLTG
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECHHHHHHHHHCCHHHHHHHHHHHHHCCCC
IPGLRGHCYRMGGDEFVIIIEPEIYNELSKIVTNIKTLFNKPWYLMETEYFCTMSMGIAL
CCCCCCEEEEECCCEEEEEECCHHHHHHHHHHHHHHHHHCCCEEEEECCEEEEEECCEEE
FPDNSVDVHEITRMADVAMYEAKRSGKNGYAYYSSEVENSTAKRLDIENNMRQAISNEIN
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEECCHHCCCHHHHCCHHHHHHHHHHHHHH
EFVVFYQPVVNVNTQMCTSCEALVRWDSKALGFMGPGEFIPLAEYLGLITSIGDYVLEEA
HEEEEEEHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
CRRCKIWNDNGHPDFYINVNLSVVQLLQKDVVENIKRILDKTGVNPKNIVLEITESFAIN
HHHCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHH
DMQRVMEIITGLKKLGPRIALDDFGTGYSSLNYIKQLPLDIIKVDKTFIDDIVEDDYAQA
HHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHH
FVKLIVDLSKTIGTKIVVEGVEHKEQFELLKSLGVDYIQGYYFGKPVPANIFEEKNLEGR
HHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHCHHHHCCEECCCCCCCCHHHCCCCCCC
LGK
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]