Click here to switch to the map view.

The map label for this gene is adhB [H]

Identifier: 238916374

GI number: 238916374

Start: 440175

End: 441398

Strand: Reverse

Name: adhB [H]

Synonym: EUBELI_00428

Alternate gene names: 238916374

Gene position: 441398-440175 (Counterclockwise)

Preceding gene: 238916375

Following gene: 238916373

Centisome position: 20.59

GC content: 41.5

Gene sequence:

>1224_bases
ATGAACATTTTCAAGAAAATATACTGCAGAAGTTTTCAGACTGTATTCAAGATTGCACTGCCATTTCTTCCATACAGGAA
GCCTAAAATTGTAAGCGCGTTGTCTGACATTCCATCTGTACTTAACAAAAAGAAGAAGTCATGTCCTGTAATTATTACTG
ATCCCGGAATTGCAAAGCTTGGCATTCTCTCTATGCTTACAGATGTATTTGACAATGCTGGCATTGAATACCATGTTTAT
GATAAAACTGTAGCTAACCCTACAACTGATACCGTGGAAGAAGCACTTGCCATATATAAAGATAACAAATGTGACTGCAT
AATCGGCTTTGGCGGCGGTTCAAGCATGGACTGTGCCAAAGCTGTTGGTGTAAGAATTGCAAGACCTAAGACACATCTGT
CTAAGCTGGGCGGAATCCTTAAGGTTCACTCAAAGCTTCCTCTGCTGGTTGCAATTCCTACAACAGCAGGAACTGGAAGT
GAAACTACTCTTGCAGCCGTAATTGTAGACGCCACAACCCGCCACAAATACGCAATCAACGACTTTCCGCTTATTCCAAG
ATATGCAGTCCTTGACCCGAAGGTAACCCTTACACTTCCTGCTTCAATTACCGCAACTACAGGAATGGATGCACTTACAC
ATGCCGTTGAAGCCTACATCGGAAACTCAACAACTCCGGGTACAAGAAAAGACGCACTTATGGCTACTGAATTAATATTT
AACAATCTTGACAGAGCATACACTAACGGTTCTGATACAACAGCAAGAAAGAATATGCTTAAAGCTGCTTATTATGCCGG
ATGTGCATTCACTAAATCATATGTAGGATATGTCCATGCAATTGCACATTCTCTAGGTGGCGAATATAATGTTCCTCATG
GACTTGCAAATGCAGTAATTCTCCCAATGGTTCTTGAAAGCTATGGAGAATCCATCTATACGAAGCTGCATGACCTTGCA
ATTGCCGCCGGTGTTGCAGATAAGGATATGCCAGATGAGACTGCTGCCAAAGCATTTATACAGGCAGTCAGAGATATGAA
AGCAAGATTTAACATTGGCGATACAATTCCTGAGATTAAAGAGGCGGATATTCCTAAGCTTGCAGGGTATGCCGACAAAG
AGGCTAATCCTCTCTACCCTGTTCCGGTTCTTATGGACGCTAAGACACTCGAACAATTCTACTATAAACTTATGAAAGAT
AATACATGTGAAAATGAGGTATGA

Upstream 100 bases:

>100_bases
TGGAACCGGACTGCAGATTCCTGACTAACCCCTTGTCAATATGAACTTCGGGTATTATAATTTGGTAGTCAAAATATTTT
AAATTCAAAAGAGGTGTACA

Downstream 100 bases:

>100_bases
TATGGAAGCTACACAAATCAATAAACTTGTACAATCGCAGCGACATTTCTTTCTTACAGGTACAACACTTGATGTAAATG
TAAGAATTGATGCCTTAAAG

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: Alcohol dehydrogenase II; ADH II [H]

Number of amino acids: Translated: 407; Mature: 407

Protein sequence:

>407_residues
MNIFKKIYCRSFQTVFKIALPFLPYRKPKIVSALSDIPSVLNKKKKSCPVIITDPGIAKLGILSMLTDVFDNAGIEYHVY
DKTVANPTTDTVEEALAIYKDNKCDCIIGFGGGSSMDCAKAVGVRIARPKTHLSKLGGILKVHSKLPLLVAIPTTAGTGS
ETTLAAVIVDATTRHKYAINDFPLIPRYAVLDPKVTLTLPASITATTGMDALTHAVEAYIGNSTTPGTRKDALMATELIF
NNLDRAYTNGSDTTARKNMLKAAYYAGCAFTKSYVGYVHAIAHSLGGEYNVPHGLANAVILPMVLESYGESIYTKLHDLA
IAAGVADKDMPDETAAKAFIQAVRDMKARFNIGDTIPEIKEADIPKLAGYADKEANPLYPVPVLMDAKTLEQFYYKLMKD
NTCENEV

Sequences:

>Translated_407_residues
MNIFKKIYCRSFQTVFKIALPFLPYRKPKIVSALSDIPSVLNKKKKSCPVIITDPGIAKLGILSMLTDVFDNAGIEYHVY
DKTVANPTTDTVEEALAIYKDNKCDCIIGFGGGSSMDCAKAVGVRIARPKTHLSKLGGILKVHSKLPLLVAIPTTAGTGS
ETTLAAVIVDATTRHKYAINDFPLIPRYAVLDPKVTLTLPASITATTGMDALTHAVEAYIGNSTTPGTRKDALMATELIF
NNLDRAYTNGSDTTARKNMLKAAYYAGCAFTKSYVGYVHAIAHSLGGEYNVPHGLANAVILPMVLESYGESIYTKLHDLA
IAAGVADKDMPDETAAKAFIQAVRDMKARFNIGDTIPEIKEADIPKLAGYADKEANPLYPVPVLMDAKTLEQFYYKLMKD
NTCENEV
>Mature_407_residues
MNIFKKIYCRSFQTVFKIALPFLPYRKPKIVSALSDIPSVLNKKKKSCPVIITDPGIAKLGILSMLTDVFDNAGIEYHVY
DKTVANPTTDTVEEALAIYKDNKCDCIIGFGGGSSMDCAKAVGVRIARPKTHLSKLGGILKVHSKLPLLVAIPTTAGTGS
ETTLAAVIVDATTRHKYAINDFPLIPRYAVLDPKVTLTLPASITATTGMDALTHAVEAYIGNSTTPGTRKDALMATELIF
NNLDRAYTNGSDTTARKNMLKAAYYAGCAFTKSYVGYVHAIAHSLGGEYNVPHGLANAVILPMVLESYGESIYTKLHDLA
IAAGVADKDMPDETAAKAFIQAVRDMKARFNIGDTIPEIKEADIPKLAGYADKEANPLYPVPVLMDAKTLEQFYYKLMKD
NTCENEV

Specific function: Unknown

COG id: COG1454

COG function: function code C; Alcohol dehydrogenase, class IV

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=356, Percent_Identity=26.4044943820225, Blast_Score=99, Evalue=7e-21,
Organism=Escherichia coli, GI48994951, Length=363, Percent_Identity=37.7410468319559, Blast_Score=210, Evalue=1e-55,
Organism=Escherichia coli, GI87082107, Length=368, Percent_Identity=33.4239130434783, Blast_Score=185, Evalue=4e-48,
Organism=Escherichia coli, GI1789163, Length=343, Percent_Identity=34.6938775510204, Blast_Score=181, Evalue=6e-47,
Organism=Escherichia coli, GI1787493, Length=429, Percent_Identity=31.4685314685315, Blast_Score=170, Evalue=1e-43,
Organism=Escherichia coli, GI1789386, Length=266, Percent_Identity=30.0751879699248, Blast_Score=80, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17537053, Length=287, Percent_Identity=26.8292682926829, Blast_Score=108, Evalue=7e-24,
Organism=Saccharomyces cerevisiae, GI6321181, Length=390, Percent_Identity=34.1025641025641, Blast_Score=196, Evalue=7e-51,
Organism=Drosophila melanogaster, GI24657991, Length=394, Percent_Identity=25.6345177664975, Blast_Score=95, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 44128; Mature: 44128

Theoretical pI: Translated: 8.24; Mature: 8.24

Prosite motif: PS01186 EGF_2 ; PS00913 ADH_IRON_1 ; PS00060 ADH_IRON_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIFKKIYCRSFQTVFKIALPFLPYRKPKIVSALSDIPSVLNKKKKSCPVIITDPGIAKL
CCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHH
GILSMLTDVFDNAGIEYHVYDKTVANPTTDTVEEALAIYKDNKCDCIIGFGGGSSMDCAK
HHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHH
AVGVRIARPKTHLSKLGGILKVHSKLPLLVAIPTTAGTGSETTLAAVIVDATTRHKYAIN
HHCCEECCCHHHHHHHCCHHEECCCCCEEEEECCCCCCCCCCEEEEEEEECCCCCEEECC
DFPLIPRYAVLDPKVTLTLPASITATTGMDALTHAVEAYIGNSTTPGTRKDALMATELIF
CCCCCCCEEEECCEEEEEECCCEECCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
NNLDRAYTNGSDTTARKNMLKAAYYAGCAFTKSYVGYVHAIAHSLGGEYNVPHGLANAVI
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
LPMVLESYGESIYTKLHDLAIAAGVADKDMPDETAAKAFIQAVRDMKARFNIGDTIPEIK
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHH
EADIPKLAGYADKEANPLYPVPVLMDAKTLEQFYYKLMKDNTCENEV
HCCCCHHCCCCCCCCCCCCCCCCEECHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MNIFKKIYCRSFQTVFKIALPFLPYRKPKIVSALSDIPSVLNKKKKSCPVIITDPGIAKL
CCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHH
GILSMLTDVFDNAGIEYHVYDKTVANPTTDTVEEALAIYKDNKCDCIIGFGGGSSMDCAK
HHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHH
AVGVRIARPKTHLSKLGGILKVHSKLPLLVAIPTTAGTGSETTLAAVIVDATTRHKYAIN
HHCCEECCCHHHHHHHCCHHEECCCCCEEEEECCCCCCCCCCEEEEEEEECCCCCEEECC
DFPLIPRYAVLDPKVTLTLPASITATTGMDALTHAVEAYIGNSTTPGTRKDALMATELIF
CCCCCCCEEEECCEEEEEECCCEECCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
NNLDRAYTNGSDTTARKNMLKAAYYAGCAFTKSYVGYVHAIAHSLGGEYNVPHGLANAVI
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
LPMVLESYGESIYTKLHDLAIAAGVADKDMPDETAAKAFIQAVRDMKARFNIGDTIPEIK
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHH
EADIPKLAGYADKEANPLYPVPVLMDAKTLEQFYYKLMKDNTCENEV
HCCCCHHCCCCCCCCCCCCCCCCEECHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3584063; 2308827; 2935393 [H]