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The map label for this gene is pepE [C]

Identifier: 238916358

GI number: 238916358

Start: 424866

End: 425468

Strand: Direct

Name: pepE [C]

Synonym: EUBELI_00411

Alternate gene names: 238916358

Gene position: 424866-425468 (Clockwise)

Preceding gene: 238916357

Following gene: 238916359

Centisome position: 19.81

GC content: 38.81

Gene sequence:

>603_bases
ATGAAACTATTTTTATGTTCGCACTTTTCAAGTGTAGGAAGTCTGATAAAGGAAGAAATTGAAAATAAGAAAGTCGCATT
TATTCCAACAGCTTCACTGCGTGAAGGCTACACCGGTTATGTCGGCTCGGCTCGAAAATTATTCAAAAAGTTGGGAGCAA
TCGTAACTGAAATTGATATTTCAACGGAGGCTTATTCAACGATACAGTCTGTTTTTGAAGAAGCAGATGTGATATATTTT
ACCGGCGGAAATTCTTTCTTTCTTATGGACCAGCTCCGTAAAACGGGAACTGATGGACTGCTGAAAAAGGAATTGGCAAA
TGGAAAATTGATGATCGGCGAGTCGGCAGGCGCAATTATATGCGCTCCAAGCATCCAATATATCGAGCAAATGGATGAAA
AGCCGGAGGACTACTCACAAGAAGATGATGCAGGGATTGATTTGATTGATTTCTATGTTCTTCCGCATTATCTTACAGCA
CCATTTAAGAAAGTTACCGAGAAAATAATGACTGAGTTTTCGGATTTGAATCTATGCCCAATTAACAACCGTCAGGGAAT
TGTAATTGATGGTGAAGATTCAAAGGTTATTTGCAAAGACTAA

Upstream 100 bases:

>100_bases
TCACTGTGGAATAAGAAGCGCCACAATCAAAAAAATAAGTAACAAGAAAAATTCAAGTTTGTAGAATAAAGAAAATCGGG
ATTTATAAAGGAGAATATTG

Downstream 100 bases:

>100_bases
TTTGAAAATTCAAGTTTATAGATTACATCTTATAAATCACCTGTAAATCACCAACTTTAAACTATATATAATAACTTTGA
TACAAAGAAACAGAGCAAGT

Product: dipeptidase E

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 200; Mature: 200

Protein sequence:

>200_residues
MKLFLCSHFSSVGSLIKEEIENKKVAFIPTASLREGYTGYVGSARKLFKKLGAIVTEIDISTEAYSTIQSVFEEADVIYF
TGGNSFFLMDQLRKTGTDGLLKKELANGKLMIGESAGAIICAPSIQYIEQMDEKPEDYSQEDDAGIDLIDFYVLPHYLTA
PFKKVTEKIMTEFSDLNLCPINNRQGIVIDGEDSKVICKD

Sequences:

>Translated_200_residues
MKLFLCSHFSSVGSLIKEEIENKKVAFIPTASLREGYTGYVGSARKLFKKLGAIVTEIDISTEAYSTIQSVFEEADVIYF
TGGNSFFLMDQLRKTGTDGLLKKELANGKLMIGESAGAIICAPSIQYIEQMDEKPEDYSQEDDAGIDLIDFYVLPHYLTA
PFKKVTEKIMTEFSDLNLCPINNRQGIVIDGEDSKVICKD
>Mature_200_residues
MKLFLCSHFSSVGSLIKEEIENKKVAFIPTASLREGYTGYVGSARKLFKKLGAIVTEIDISTEAYSTIQSVFEEADVIYF
TGGNSFFLMDQLRKTGTDGLLKKELANGKLMIGESAGAIICAPSIQYIEQMDEKPEDYSQEDDAGIDLIDFYVLPHYLTA
PFKKVTEKIMTEFSDLNLCPINNRQGIVIDGEDSKVICKD

Specific function: Hydrolyzes Dipeptides Containing N-Terminal Aspartate Residues. May Play A Role In Allowing The Cell To Use Peptide Aspartate To Spare Carbon Otherwise Required For The Synthesis Of The Aspartate Family Of Amino Acids. [C]

COG id: COG3340

COG function: function code E; Peptidase E

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S51 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005320 [H]

Pfam domain/function: PF03575 Peptidase_S51 [H]

EC number: 3.4.13.21 [C]

Molecular weight: Translated: 22237; Mature: 22237

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLFLCSHFSSVGSLIKEEIENKKVAFIPTASLREGYTGYVGSARKLFKKLGAIVTEIDI
CEEEEEHHHHHHHHHHHHHHCCCEEEEEECHHHHCCCCCCCHHHHHHHHHHHHHHHHCCC
STEAYSTIQSVFEEADVIYFTGGNSFFLMDQLRKTGTDGLLKKELANGKLMIGESAGAII
CHHHHHHHHHHHHCCCEEEEECCCEEEEHHHHHHCCCCHHHHHHHCCCCEEEECCCCEEE
CAPSIQYIEQMDEKPEDYSQEDDAGIDLIDFYVLPHYLTAPFKKVTEKIMTEFSDLNLCP
ECCCHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCEEE
INNRQGIVIDGEDSKVICKD
CCCCCEEEEECCCCEEEECC
>Mature Secondary Structure
MKLFLCSHFSSVGSLIKEEIENKKVAFIPTASLREGYTGYVGSARKLFKKLGAIVTEIDI
CEEEEEHHHHHHHHHHHHHHCCCEEEEEECHHHHCCCCCCCHHHHHHHHHHHHHHHHCCC
STEAYSTIQSVFEEADVIYFTGGNSFFLMDQLRKTGTDGLLKKELANGKLMIGESAGAII
CHHHHHHHHHHHHCCCEEEEECCCEEEEHHHHHHCCCCHHHHHHHCCCCEEEECCCCEEE
CAPSIQYIEQMDEKPEDYSQEDDAGIDLIDFYVLPHYLTAPFKKVTEKIMTEFSDLNLCP
ECCCHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCEEE
INNRQGIVIDGEDSKVICKD
CCCCCEEEEECCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]