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The map label for this gene is apeB [H]

Identifier: 238916318

GI number: 238916318

Start: 378664

End: 379995

Strand: Direct

Name: apeB [H]

Synonym: EUBELI_00352

Alternate gene names: 238916318

Gene position: 378664-379995 (Clockwise)

Preceding gene: 238916317

Following gene: 238916319

Centisome position: 17.66

GC content: 42.79

Gene sequence:

>1332_bases
ATGGAAGAGAACACATTTATAAATGTATCAAAAGATATGATGTCGTTCATAGAAAAAAGTCCTACAGCATTTCATGTAAC
GGCGAATTTTATGGATTTGCTGGACGATGCCGGATTTGTGCGCCTTAACGAAAGGGACAGATGGCATCTTATATCTGGCG
GCAAATACTACGCTACAAGAAACGATTCTTCCATAATAGCATTCAGGATGCCTGCCACAGAGGGTTTTGCTAATTACCAG
ATTGCAGCCGCACACAGTGATTCACCGTCATTTAAGGTAAAAGAGAATCCTGAGCTGACACCGGACAAGAATTACGTTTC
GTTAAATGTGGAAAAATACGGCGGCATGCTTATGGCACCGTGGTTTGACCGGCCTCTTTCGGTTGCTGGAAGGGCAATAG
TAAGAGAAGGTGCAGTATTAAAGCCTGTCCTTGTAAATGTAGACAGGGATTTATGCATAATACCAAATCTTGCAATTCAC
ATGAACAGGGAAGCCAACACAGGGCTTAATTATAATGCACAGAAGGATATGATACCGCTTATAGGAGAGGCAGAATCCAA
AGGGCTTTTTGACAGCATAATAGCAGACGCTGCACAGACAGATAAAGAGTCAGTGATAAGCAGTGATCTGTTTCTGTATA
ACAGACAGGCAGGAACTATATGGGGTGCGGATAATGAATTTATATCAGCACCAAGACTTGATGATGTGATGTGTGCATAT
TCATGCATGAACGCGCTTATAGACAGTGATGAGAGCAACCAGGAAAGCGTTGCGGTATGTGCGGTATTTGACAATGAAGA
GGTTGGCAGCAGCACCAAGCAGGGAGCAGATTCAACATTTTTATCAGATGTGCTTATGCGTATAGCTGCGTGTGCCGGCA
AGGATAATGAGGATTATATAAGGGCGTGTGCAGGTTCTTTCATGCTTTCAGCGGACAATGCGCATGCGGTTCATCCTAAT
TATCAGGAGAAAGCTGATCCGACTAACAGACCTCATATGAACAAAGGTATAGTCATCAAATACAATGCCAACCAGAAATA
CACAACAGATGCGGTTTCTGCGGCAATATTTAAAGAAATATGTACAAGAGCGGGAGTTCCGACACAGGAATTTGCTAACC
GTTCAGATATTCCGGGTGGTTCAACACTTGGAAATATAGCTAACTGCCATGTGTCAATGAACACAGTAGATATCGGGCTT
GCGCAGCTTGCAATGCACTCACCTTACGAGACAGCAGGAATTATGGACACAGAATACATGATAAAGGCAGTAAAAGAATT
TTTCGAGACAGCCATTGTGACTAACAGCAACGGCACATTTACATTAGAATAA

Upstream 100 bases:

>100_bases
GGTGGTAATAGTTATTGTAATAATTATAACAGTAGTCATGATGGTACAGAATAATAAAAGAAAAAGAAGATATAACAGAC
GCAGATAGAAGGGAGCAGTT

Downstream 100 bases:

>100_bases
CAGAAAGATACAGTATATGAGCAATACTATATATATGGCCCCAATGGAGGGGCTTACAGATTTTACATACCGTAACGCCT
ACGAGAAAACATTTGGAAAA

Product: aminopeptidase 2

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 443; Mature: 443

Protein sequence:

>443_residues
MEENTFINVSKDMMSFIEKSPTAFHVTANFMDLLDDAGFVRLNERDRWHLISGGKYYATRNDSSIIAFRMPATEGFANYQ
IAAAHSDSPSFKVKENPELTPDKNYVSLNVEKYGGMLMAPWFDRPLSVAGRAIVREGAVLKPVLVNVDRDLCIIPNLAIH
MNREANTGLNYNAQKDMIPLIGEAESKGLFDSIIADAAQTDKESVISSDLFLYNRQAGTIWGADNEFISAPRLDDVMCAY
SCMNALIDSDESNQESVAVCAVFDNEEVGSSTKQGADSTFLSDVLMRIAACAGKDNEDYIRACAGSFMLSADNAHAVHPN
YQEKADPTNRPHMNKGIVIKYNANQKYTTDAVSAAIFKEICTRAGVPTQEFANRSDIPGGSTLGNIANCHVSMNTVDIGL
AQLAMHSPYETAGIMDTEYMIKAVKEFFETAIVTNSNGTFTLE

Sequences:

>Translated_443_residues
MEENTFINVSKDMMSFIEKSPTAFHVTANFMDLLDDAGFVRLNERDRWHLISGGKYYATRNDSSIIAFRMPATEGFANYQ
IAAAHSDSPSFKVKENPELTPDKNYVSLNVEKYGGMLMAPWFDRPLSVAGRAIVREGAVLKPVLVNVDRDLCIIPNLAIH
MNREANTGLNYNAQKDMIPLIGEAESKGLFDSIIADAAQTDKESVISSDLFLYNRQAGTIWGADNEFISAPRLDDVMCAY
SCMNALIDSDESNQESVAVCAVFDNEEVGSSTKQGADSTFLSDVLMRIAACAGKDNEDYIRACAGSFMLSADNAHAVHPN
YQEKADPTNRPHMNKGIVIKYNANQKYTTDAVSAAIFKEICTRAGVPTQEFANRSDIPGGSTLGNIANCHVSMNTVDIGL
AQLAMHSPYETAGIMDTEYMIKAVKEFFETAIVTNSNGTFTLE
>Mature_443_residues
MEENTFINVSKDMMSFIEKSPTAFHVTANFMDLLDDAGFVRLNERDRWHLISGGKYYATRNDSSIIAFRMPATEGFANYQ
IAAAHSDSPSFKVKENPELTPDKNYVSLNVEKYGGMLMAPWFDRPLSVAGRAIVREGAVLKPVLVNVDRDLCIIPNLAIH
MNREANTGLNYNAQKDMIPLIGEAESKGLFDSIIADAAQTDKESVISSDLFLYNRQAGTIWGADNEFISAPRLDDVMCAY
SCMNALIDSDESNQESVAVCAVFDNEEVGSSTKQGADSTFLSDVLMRIAACAGKDNEDYIRACAGSFMLSADNAHAVHPN
YQEKADPTNRPHMNKGIVIKYNANQKYTTDAVSAAIFKEICTRAGVPTQEFANRSDIPGGSTLGNIANCHVSMNTVDIGL
AQLAMHSPYETAGIMDTEYMIKAVKEFFETAIVTNSNGTFTLE

Specific function: Unknown

COG id: COG1362

COG function: function code E; Aspartyl aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M18 family [H]

Homologues:

Organism=Homo sapiens, GI156416028, Length=452, Percent_Identity=34.9557522123894, Blast_Score=274, Evalue=1e-73,
Organism=Caenorhabditis elegans, GI17552916, Length=432, Percent_Identity=35.4166666666667, Blast_Score=246, Evalue=3e-65,
Organism=Saccharomyces cerevisiae, GI6321905, Length=461, Percent_Identity=36.2255965292842, Blast_Score=280, Evalue=2e-76,
Organism=Saccharomyces cerevisiae, GI6322746, Length=462, Percent_Identity=29.8701298701299, Blast_Score=202, Evalue=1e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022984
- InterPro:   IPR001948 [H]

Pfam domain/function: PF02127 Peptidase_M18 [H]

EC number: NA

Molecular weight: Translated: 48605; Mature: 48605

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEENTFINVSKDMMSFIEKSPTAFHVTANFMDLLDDAGFVRLNERDRWHLISGGKYYATR
CCCCEEEEECHHHHHHHHCCCCEEEEEHHHHHHHCCCCEEEECCCCCEEEEECCEEEEEC
NDSSIIAFRMPATEGFANYQIAAAHSDSPSFKVKENPELTPDKNYVSLNVEKYGGMLMAP
CCCEEEEEECCCCCCCCCEEEEEECCCCCCEEECCCCCCCCCCCEEEEEEHHHCCEEEEC
WFDRPLSVAGRAIVREGAVLKPVLVNVDRDLCIIPNLAIHMNREANTGLNYNAQKDMIPL
CCCCCHHHHHHHHHHCCCEECEEEEECCCCEEEECCEEEEECCCCCCCCCCCCCCCCEEE
IGEAESKGLFDSIIADAAQTDKESVISSDLFLYNRQAGTIWGADNEFISAPRLDDVMCAY
CCCCCCCCHHHHHHHHHHHCCHHHHHHHHEEEEECCCCEEECCCCCEECCCCHHHHHHHH
SCMNALIDSDESNQESVAVCAVFDNEEVGSSTKQGADSTFLSDVLMRIAACAGKDNEDYI
HHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHH
RACAGSFMLSADNAHAVHPNYQEKADPTNRPHMNKGIVIKYNANQKYTTDAVSAAIFKEI
HHHHCCEEEECCCCCEECCCCHHCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHH
CTRAGVPTQEFANRSDIPGGSTLGNIANCHVSMNTVDIGLAQLAMHSPYETAGIMDTEYM
HHHCCCCHHHHCCCCCCCCCCCCCCEEEEEEEECCHHHHHHHHHHCCCCCCCCCCCHHHH
IKAVKEFFETAIVTNSNGTFTLE
HHHHHHHHHHEEEECCCCCEEEC
>Mature Secondary Structure
MEENTFINVSKDMMSFIEKSPTAFHVTANFMDLLDDAGFVRLNERDRWHLISGGKYYATR
CCCCEEEEECHHHHHHHHCCCCEEEEEHHHHHHHCCCCEEEECCCCCEEEEECCEEEEEC
NDSSIIAFRMPATEGFANYQIAAAHSDSPSFKVKENPELTPDKNYVSLNVEKYGGMLMAP
CCCEEEEEECCCCCCCCCEEEEEECCCCCCEEECCCCCCCCCCCEEEEEEHHHCCEEEEC
WFDRPLSVAGRAIVREGAVLKPVLVNVDRDLCIIPNLAIHMNREANTGLNYNAQKDMIPL
CCCCCHHHHHHHHHHCCCEECEEEEECCCCEEEECCEEEEECCCCCCCCCCCCCCCCEEE
IGEAESKGLFDSIIADAAQTDKESVISSDLFLYNRQAGTIWGADNEFISAPRLDDVMCAY
CCCCCCCCHHHHHHHHHHHCCHHHHHHHHEEEEECCCCEEECCCCCEECCCCHHHHHHHH
SCMNALIDSDESNQESVAVCAVFDNEEVGSSTKQGADSTFLSDVLMRIAACAGKDNEDYI
HHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHH
RACAGSFMLSADNAHAVHPNYQEKADPTNRPHMNKGIVIKYNANQKYTTDAVSAAIFKEI
HHHHCCEEEECCCCCEECCCCHHCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHH
CTRAGVPTQEFANRSDIPGGSTLGNIANCHVSMNTVDIGLAQLAMHSPYETAGIMDTEYM
HHHCCCCHHHHCCCCCCCCCCCCCCEEEEEEEECCHHHHHHHHHHCCCCCCCCCCCHHHH
IKAVKEFFETAIVTNSNGTFTLE
HHHHHHHHHHEEEECCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11466286 [H]