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The map label for this gene is rpoB [H]

Identifier: 238916249

GI number: 238916249

Start: 311223

End: 315200

Strand: Direct

Name: rpoB [H]

Synonym: EUBELI_00283

Alternate gene names: 238916249

Gene position: 311223-315200 (Clockwise)

Preceding gene: 238916248

Following gene: 238916250

Centisome position: 14.51

GC content: 40.27

Gene sequence:

>3978_bases
ATGGAGAAAAACAGATTACGCCCAATAACGTCGGGCAAGGCAATGCGTATGAGTTTCTCAAGACAGAAAGAAGTTCTTGA
GATGCCTAACCTTATTGAGGTGCAGAAGGATTCTTACCAGTGGTTTTTGAATGAAGGCTTGAAAGAGGTCTTTGATGACA
TATCTCCAATTGCAGACTATAATGGAAGATTAAGTCTGGAATTCGTAGATTTTGCGTTATGTGAAGACGAAGTTAAGTAT
TCAATTGAAGAGTGTAAAGAAAGAGATGCTACATATGCAGCGCCTCTTAAGGTTACAGTAAGACTTCATAACAAAGAGAC
AGAAAGCATCAGCGAGCATGAGATTTTCATGGGAGACCTGCCATTAATGACTAAGACAGGTACATTTGTAATTAATGGTG
CTGAACGAGTTATTGTCAGCCAGTTGGTACGTTCACCTGGTATTTATTATGATATACAGAAAGATAAGTATGGTAAGATT
TTCTTGTACAGCTGTCAGGTAATTCCTAACAGAGGTGCATGGTTAGAGTATGAAACAGATGCTAATGATATATTCTATGT
TAAGGTTGACCGTAATAAGAAGGTTCCTATTACTGTTCTTATCAGAGCATTAGGATTTGGTACTAATGCGGAGATTCTTG
ATATTTTTGGTGAGGAACCTAAGCTTCTTGCTACTATGGAGAAGGATACTTCTACTAACTATCAGGAAGGTATTCTTGAA
CTTTATAAGAAGTTAAGACCAGGAGAACCATTATCTGTAGAGAGTGCTGAAGCACTTATTTCAGGTATGTTCTTTGACCC
AAGAAGATATGATCTTGCACACGTAGGAAGATATAAGTTTAATAAGAAGCTTTCTTTCAAGAGCAGAATTACAGGACAGG
TTCTTGCTGAGGATGTTGTTGATGAGAACGGAACTGTTATTGCAACAGCAGGTGAGAAGCTTACAAGAGAATCAGCACAG
GCTATTCAGGATGCAGCTGTTCCTTCAGTATTCATTACTGTAGAAGTTAAGGCTGCTGATGGTACAGTATCTGACAGAGT
TGTTAAGATTCTTTCTAACCGTGCGGTTGATATTACTAAATGGGTTGATATCAGCGAAGAAGAAGCTAAGGAGCTTGGTG
TAACAGAGTATGTATACTATCCTGTTCTTGCACAGATTCTTGCTGAGAATGAATCTTTAGAGGATATTAAGGAAGCTATT
ACTAAGAATATTGCTGATCTTATTCCTAAGCATATTACAGTGGAAGATATTCTTGCTTCTATTAATTATAATATGCACCT
TGAATATGGTGTTGGTACTAAGGATGATATCGATCACCTTGGAAACAGACGTATCAGAGCTGTAGGAGAGCTTCTTCAGA
ACCAGTTCAGAATTGGTATCTCAAGAATGGAAAGAGTGGTCCGTGAGAGAATGTCTACACAGGATCTTAGCGGAATATCT
CCACAGTCACTTATTAATATTAAGCCTGTAACAGCTGCTATTAAGGAATTCTTTGGAAGTTCGCAGTTGTCACAGTTCAT
GGATCAGAATAACCCTCTTAGTGAGATTACTCATAAGAGACGTCTTTCAGCCCTTGGTCCTGGTGGTCTTTCAAGAGATC
GTGCAGGTTTCGAGGTTCGAGATGTACACTATACTCATTATGGTAGAATGTGTCCTATCGAGACTCCTGAAGGACCTAAC
ATTGGTCTTATTAACTCTCTTGCATCTTATGCAAGAATTAATGAATATGGATTCGTTGAAGCTCCTTATCGTATTGTAGA
TAAGTCTGATCCTAAGAATCCAAGAGTTACTGATGAAGTGCGTTACTTCACAGCTGATGAGGAAGATGATTTCCATGTAG
CACAGGCTAATGCTGAGATTGATGAGAATGGTTATTTCGTAAGAAATACTGTATCTGGACGTTACAGAGAAGAAACTTCT
CAGTTCGATAAAAGCCAGATTGATCTTATGGATGTATCTCCTAAGATGGTATTCTCAGTTGCTACATCAATGATTCCATT
CCTTCAGAATGATGACTGTACACGTGCCCTCATGGGTTCTAACATGCAGCGTCAGGCCGTACCTCTTCTTATGACAGAAG
CTCCTGTTATCGGAACTGGTATTGAGAATAAGACTGCTGTTGACTCAGGTGTATGTGTAGTTGCAGAGGCTGATGGTGTT
GTTCTTTCTTCTGAATCTAACAAGATTGTTATCAGAGAAAAGGATGGCAAGGCGCGCGAATACAAGCTTACTAAGTTCTC
AAGAAGTAACCAGAGTAACTGCTATAACCAGAGACCTATTGTTTTCAAGGGTGATGAGGTTAAGGCAGGAGATGTTATTG
CTGATGGTCCATCTACATCTAATGGTGAGATTGCTCTCGGTAAGAACCCTCTTATCGGTTTCATGACTTGGGAAGGTTAT
AACTACGAGGATGCTGTACTTCTTAGTGAGCGTCTCGTAAGAGATGATGTGTATACATCTATTCATATTGAAGAATATGA
GACAGAAGCAAGAGATACTAAGTTAGGACCTGAAGAGATTACAAGAGATCTTCCTTCAACAGGTTCAGACGCTGTCAAGG
ATCTTGATGAGAACGGTATTATCCGCGTTGGTGCTGAGGTAAGAGCCGGAGATATTCTTGTTGGAAAGGTTACTCCTAAG
GGTGAGACAGAGCTTACTGCTGAAGAGAGACTTCTTAGAGCTATCTTTGGTGAGAAGGCAAGAGAAGTAAGAGATACTTC
ACTTAAGGTACCTCATGGTGCTTATGGTATTGTCGTTGCTGTTAAGACATTTACAAGAGAGAACGGAGATGAACTCTCAC
CAGGAGTTAACAAATCTGTTCGTATATATATTGCACAGAAGAGAAAGATCGGCGTTGGTGATAAGATGGCTGGTCGTCAT
GGTAACAAGGGTGTCGTTTCAAGAGTACTTCCTGTTGAAGATATGCCATTCCTTCCTAATGGCCGTCCTCTTGATATCGT
ACTTAACCCACTGGGCGTTCCTTCACGAATGAACATTGGACAGGTCCTTGAGATTCATTTGAGTCTTGCTGCCAAGGTAC
TTGGATTTAACATTTCTACTCCAGTATTCGATGGTGCAGATGAGAATGATATTATGGATACTCTTGATATGGCAAATGCT
TATGCTAACCATCCATTCGATGATGAAGAGCTTGCAGCCCAGAAGGCTGAGGCTGAGAAGAATGGCGAAGAATATCCTGA
GGATATGGTTACATTTACAGCACAGTATAAAGATGTTCTTAATAAAGAGGTATTTGATTACCTTTCAGAACACAGAGATC
ACAGAGCTGAGTGGAAGGGTGTTCCAATCGGCCGTGATGGTAAAGTAAGACTTAGAGATGGTAGAACAGGTGAGTACTTC
GACAGCCCTGTAACTATCGGATTCATGCATTACTTAAAGCTTCATCATCTTGTTGATGATAAGATTCATGCACGTTCAAC
TGGTCCTTACTCACTTGTAACTCAGCAGCCACTTGGTGGTAAGGCTCAGTTCGGTGGACAGAGATTCGGAGAGATGGAAG
TTTGGGCACTTGAGGCTTATGGTGCTGCTTATACTCTTCAGGAAATTCTTACTGTTAAGTCTGATGATGTTGTAGGACGA
GTTAAGACTTACGAAGCTATTATTAAGGGTGAGAATATTCCTGAACCAGGAGTTCCAGAATCATTCAAGGTTCTTCTTAA
GGAACTTCAGTCACTCGCACTTGATGTTAGAGTTCTTGATCAGGACAACAATGAAGTCAGACTTCTTGAGAGTTCTGAAT
ATGAAGTTACTGATTTCAAGAAGGTTCTTGATGAAGGTAATGGATACAGAAGAAACAGCAGAGAGGAAGAGGCAGAGTAC
AAGGCTGGCGGTATGTCAACAGTTACTCTTAATGAAGATGGAACAGAAGATGCTGTAGATTCAGATGATGGTGCTGATTT
TGATATGGCCGATGATTTTGATGATGATTACGGCGATGGCAATTCAGATGAATATTAA

Upstream 100 bases:

>100_bases
CTATGGACAATGCACTATTGTGGTAAATTGTGCTTATTCTTTGCACATTTACTGATAATGTAATATATTAATGTGAAGAA
AACTAAGGGGTGAAACGTCA

Downstream 100 bases:

>100_bases
TTAGAAGGGAGCACTATAATGGCAGAAGAAATTAAATCAAATAAGTCAATGAAATTTGATAAGATTCAGATCAAGCTTGC
TTCTCCTGAGAATATTTTGG

Product: DNA-directed RNA polymerase

Products: NA

Alternate protein names: RNAP subunit beta; RNA polymerase subunit beta; Transcriptase subunit beta [H]

Number of amino acids: Translated: 1325; Mature: 1325

Protein sequence:

>1325_residues
MEKNRLRPITSGKAMRMSFSRQKEVLEMPNLIEVQKDSYQWFLNEGLKEVFDDISPIADYNGRLSLEFVDFALCEDEVKY
SIEECKERDATYAAPLKVTVRLHNKETESISEHEIFMGDLPLMTKTGTFVINGAERVIVSQLVRSPGIYYDIQKDKYGKI
FLYSCQVIPNRGAWLEYETDANDIFYVKVDRNKKVPITVLIRALGFGTNAEILDIFGEEPKLLATMEKDTSTNYQEGILE
LYKKLRPGEPLSVESAEALISGMFFDPRRYDLAHVGRYKFNKKLSFKSRITGQVLAEDVVDENGTVIATAGEKLTRESAQ
AIQDAAVPSVFITVEVKAADGTVSDRVVKILSNRAVDITKWVDISEEEAKELGVTEYVYYPVLAQILAENESLEDIKEAI
TKNIADLIPKHITVEDILASINYNMHLEYGVGTKDDIDHLGNRRIRAVGELLQNQFRIGISRMERVVRERMSTQDLSGIS
PQSLINIKPVTAAIKEFFGSSQLSQFMDQNNPLSEITHKRRLSALGPGGLSRDRAGFEVRDVHYTHYGRMCPIETPEGPN
IGLINSLASYARINEYGFVEAPYRIVDKSDPKNPRVTDEVRYFTADEEDDFHVAQANAEIDENGYFVRNTVSGRYREETS
QFDKSQIDLMDVSPKMVFSVATSMIPFLQNDDCTRALMGSNMQRQAVPLLMTEAPVIGTGIENKTAVDSGVCVVAEADGV
VLSSESNKIVIREKDGKAREYKLTKFSRSNQSNCYNQRPIVFKGDEVKAGDVIADGPSTSNGEIALGKNPLIGFMTWEGY
NYEDAVLLSERLVRDDVYTSIHIEEYETEARDTKLGPEEITRDLPSTGSDAVKDLDENGIIRVGAEVRAGDILVGKVTPK
GETELTAEERLLRAIFGEKAREVRDTSLKVPHGAYGIVVAVKTFTRENGDELSPGVNKSVRIYIAQKRKIGVGDKMAGRH
GNKGVVSRVLPVEDMPFLPNGRPLDIVLNPLGVPSRMNIGQVLEIHLSLAAKVLGFNISTPVFDGADENDIMDTLDMANA
YANHPFDDEELAAQKAEAEKNGEEYPEDMVTFTAQYKDVLNKEVFDYLSEHRDHRAEWKGVPIGRDGKVRLRDGRTGEYF
DSPVTIGFMHYLKLHHLVDDKIHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEILTVKSDDVVGR
VKTYEAIIKGENIPEPGVPESFKVLLKELQSLALDVRVLDQDNNEVRLLESSEYEVTDFKKVLDEGNGYRRNSREEEAEY
KAGGMSTVTLNEDGTEDAVDSDDGADFDMADDFDDDYGDGNSDEY

Sequences:

>Translated_1325_residues
MEKNRLRPITSGKAMRMSFSRQKEVLEMPNLIEVQKDSYQWFLNEGLKEVFDDISPIADYNGRLSLEFVDFALCEDEVKY
SIEECKERDATYAAPLKVTVRLHNKETESISEHEIFMGDLPLMTKTGTFVINGAERVIVSQLVRSPGIYYDIQKDKYGKI
FLYSCQVIPNRGAWLEYETDANDIFYVKVDRNKKVPITVLIRALGFGTNAEILDIFGEEPKLLATMEKDTSTNYQEGILE
LYKKLRPGEPLSVESAEALISGMFFDPRRYDLAHVGRYKFNKKLSFKSRITGQVLAEDVVDENGTVIATAGEKLTRESAQ
AIQDAAVPSVFITVEVKAADGTVSDRVVKILSNRAVDITKWVDISEEEAKELGVTEYVYYPVLAQILAENESLEDIKEAI
TKNIADLIPKHITVEDILASINYNMHLEYGVGTKDDIDHLGNRRIRAVGELLQNQFRIGISRMERVVRERMSTQDLSGIS
PQSLINIKPVTAAIKEFFGSSQLSQFMDQNNPLSEITHKRRLSALGPGGLSRDRAGFEVRDVHYTHYGRMCPIETPEGPN
IGLINSLASYARINEYGFVEAPYRIVDKSDPKNPRVTDEVRYFTADEEDDFHVAQANAEIDENGYFVRNTVSGRYREETS
QFDKSQIDLMDVSPKMVFSVATSMIPFLQNDDCTRALMGSNMQRQAVPLLMTEAPVIGTGIENKTAVDSGVCVVAEADGV
VLSSESNKIVIREKDGKAREYKLTKFSRSNQSNCYNQRPIVFKGDEVKAGDVIADGPSTSNGEIALGKNPLIGFMTWEGY
NYEDAVLLSERLVRDDVYTSIHIEEYETEARDTKLGPEEITRDLPSTGSDAVKDLDENGIIRVGAEVRAGDILVGKVTPK
GETELTAEERLLRAIFGEKAREVRDTSLKVPHGAYGIVVAVKTFTRENGDELSPGVNKSVRIYIAQKRKIGVGDKMAGRH
GNKGVVSRVLPVEDMPFLPNGRPLDIVLNPLGVPSRMNIGQVLEIHLSLAAKVLGFNISTPVFDGADENDIMDTLDMANA
YANHPFDDEELAAQKAEAEKNGEEYPEDMVTFTAQYKDVLNKEVFDYLSEHRDHRAEWKGVPIGRDGKVRLRDGRTGEYF
DSPVTIGFMHYLKLHHLVDDKIHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEILTVKSDDVVGR
VKTYEAIIKGENIPEPGVPESFKVLLKELQSLALDVRVLDQDNNEVRLLESSEYEVTDFKKVLDEGNGYRRNSREEEAEY
KAGGMSTVTLNEDGTEDAVDSDDGADFDMADDFDDDYGDGNSDEY
>Mature_1325_residues
MEKNRLRPITSGKAMRMSFSRQKEVLEMPNLIEVQKDSYQWFLNEGLKEVFDDISPIADYNGRLSLEFVDFALCEDEVKY
SIEECKERDATYAAPLKVTVRLHNKETESISEHEIFMGDLPLMTKTGTFVINGAERVIVSQLVRSPGIYYDIQKDKYGKI
FLYSCQVIPNRGAWLEYETDANDIFYVKVDRNKKVPITVLIRALGFGTNAEILDIFGEEPKLLATMEKDTSTNYQEGILE
LYKKLRPGEPLSVESAEALISGMFFDPRRYDLAHVGRYKFNKKLSFKSRITGQVLAEDVVDENGTVIATAGEKLTRESAQ
AIQDAAVPSVFITVEVKAADGTVSDRVVKILSNRAVDITKWVDISEEEAKELGVTEYVYYPVLAQILAENESLEDIKEAI
TKNIADLIPKHITVEDILASINYNMHLEYGVGTKDDIDHLGNRRIRAVGELLQNQFRIGISRMERVVRERMSTQDLSGIS
PQSLINIKPVTAAIKEFFGSSQLSQFMDQNNPLSEITHKRRLSALGPGGLSRDRAGFEVRDVHYTHYGRMCPIETPEGPN
IGLINSLASYARINEYGFVEAPYRIVDKSDPKNPRVTDEVRYFTADEEDDFHVAQANAEIDENGYFVRNTVSGRYREETS
QFDKSQIDLMDVSPKMVFSVATSMIPFLQNDDCTRALMGSNMQRQAVPLLMTEAPVIGTGIENKTAVDSGVCVVAEADGV
VLSSESNKIVIREKDGKAREYKLTKFSRSNQSNCYNQRPIVFKGDEVKAGDVIADGPSTSNGEIALGKNPLIGFMTWEGY
NYEDAVLLSERLVRDDVYTSIHIEEYETEARDTKLGPEEITRDLPSTGSDAVKDLDENGIIRVGAEVRAGDILVGKVTPK
GETELTAEERLLRAIFGEKAREVRDTSLKVPHGAYGIVVAVKTFTRENGDELSPGVNKSVRIYIAQKRKIGVGDKMAGRH
GNKGVVSRVLPVEDMPFLPNGRPLDIVLNPLGVPSRMNIGQVLEIHLSLAAKVLGFNISTPVFDGADENDIMDTLDMANA
YANHPFDDEELAAQKAEAEKNGEEYPEDMVTFTAQYKDVLNKEVFDYLSEHRDHRAEWKGVPIGRDGKVRLRDGRTGEYF
DSPVTIGFMHYLKLHHLVDDKIHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEILTVKSDDVVGR
VKTYEAIIKGENIPEPGVPESFKVLLKELQSLALDVRVLDQDNNEVRLLESSEYEVTDFKKVLDEGNGYRRNSREEEAEY
KAGGMSTVTLNEDGTEDAVDSDDGADFDMADDFDDDYGDGNSDEY

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates [H]

COG id: COG0085

COG function: function code K; DNA-directed RNA polymerase, beta subunit/140 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta chain family [H]

Homologues:

Organism=Homo sapiens, GI4505941, Length=480, Percent_Identity=28.3333333333333, Blast_Score=151, Evalue=5e-36,
Organism=Homo sapiens, GI238908503, Length=483, Percent_Identity=26.9151138716356, Blast_Score=137, Evalue=7e-32,
Organism=Homo sapiens, GI238908505, Length=483, Percent_Identity=26.9151138716356, Blast_Score=137, Evalue=8e-32,
Organism=Homo sapiens, GI33469941, Length=268, Percent_Identity=26.1194029850746, Blast_Score=91, Evalue=9e-18,
Organism=Homo sapiens, GI212286172, Length=249, Percent_Identity=26.5060240963855, Blast_Score=91, Evalue=9e-18,
Organism=Escherichia coli, GI1790419, Length=523, Percent_Identity=58.508604206501, Blast_Score=636, Evalue=0.0,
Organism=Caenorhabditis elegans, GI25144348, Length=508, Percent_Identity=27.9527559055118, Blast_Score=147, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI17552304, Length=495, Percent_Identity=27.4747474747475, Blast_Score=146, Evalue=9e-35,
Organism=Caenorhabditis elegans, GI17506623, Length=244, Percent_Identity=29.5081967213115, Blast_Score=106, Evalue=7e-23,
Organism=Saccharomyces cerevisiae, GI6324781, Length=477, Percent_Identity=24.9475890985325, Blast_Score=127, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6324725, Length=238, Percent_Identity=28.1512605042017, Blast_Score=99, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6325267, Length=89, Percent_Identity=40.4494382022472, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI17136444, Length=481, Percent_Identity=27.2349272349272, Blast_Score=145, Evalue=3e-34,
Organism=Drosophila melanogaster, GI17647877, Length=473, Percent_Identity=26.4270613107822, Blast_Score=134, Evalue=5e-31,
Organism=Drosophila melanogaster, GI17136446, Length=493, Percent_Identity=26.1663286004057, Blast_Score=115, Evalue=1e-25,

Paralogues:

None

Copy number: 4233 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010243
- InterPro:   IPR019462
- InterPro:   IPR015712
- InterPro:   IPR007120
- InterPro:   IPR007121
- InterPro:   IPR007644
- InterPro:   IPR007642
- InterPro:   IPR007645
- InterPro:   IPR007641
- InterPro:   IPR014724 [H]

Pfam domain/function: PF04563 RNA_pol_Rpb2_1; PF04561 RNA_pol_Rpb2_2; PF04565 RNA_pol_Rpb2_3; PF10385 RNA_pol_Rpb2_45; PF00562 RNA_pol_Rpb2_6; PF04560 RNA_pol_Rpb2_7 [H]

EC number: =2.7.7.6 [H]

Molecular weight: Translated: 148179; Mature: 148179

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: PS01166 RNA_POL_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKNRLRPITSGKAMRMSFSRQKEVLEMPNLIEVQKDSYQWFLNEGLKEVFDDISPIADY
CCCCCCCCCCCCCCEEHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHCC
NGRLSLEFVDFALCEDEVKYSIEECKERDATYAAPLKVTVRLHNKETESISEHEIFMGDL
CCEEEEEEEHHHHHHHHHHHHHHHHHHCCCCEECCEEEEEEEECCCCCCCCCCEEEECCC
PLMTKTGTFVINGAERVIVSQLVRSPGIYYDIQKDKYGKIFLYSCQVIPNRGAWLEYETD
CCEEECCEEEECCHHHHHHHHHHHCCCEEEEECCCCCCEEEEEEEEEECCCCCEEEEECC
ANDIFYVKVDRNKKVPITVLIRALGFGTNAEILDIFGEEPKLLATMEKDTSTNYQEGILE
CCEEEEEEECCCCCCCHHHHHHHHCCCCCCCEEEECCCCCCEEEEECCCCCCCHHHHHHH
LYKKLRPGEPLSVESAEALISGMFFDPRRYDLAHVGRYKFNKKLSFKSRITGQVLAEDVV
HHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCHHHHCHHHCCCCCCHHHHHHHHHHHHHHH
DENGTVIATAGEKLTRESAQAIQDAAVPSVFITVEVKAADGTVSDRVVKILSNRAVDITK
CCCCCEEEECCHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCHHHHHHHHHHCCCEEEEE
WVDISEEEAKELGVTEYVYYPVLAQILAENESLEDIKEAITKNIADLIPKHITVEDILAS
ECCCCHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHH
INYNMHLEYGVGTKDDIDHLGNRRIRAVGELLQNQFRIGISRMERVVRERMSTQDLSGIS
CCCCEEEEECCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCC
PQSLINIKPVTAAIKEFFGSSQLSQFMDQNNPLSEITHKRRLSALGPGGLSRDRAGFEVR
HHHEEECCHHHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEE
DVHYTHYGRMCPIETPEGPNIGLINSLASYARINEYGFVEAPYRIVDKSDPKNPRVTDEV
EEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCE
RYFTADEEDDFHVAQANAEIDENGYFVRNTVSGRYREETSQFDKSQIDLMDVSPKMVFSV
EEEECCCCCCEEEEECCCEECCCCCEEEECCCCCHHHHHHHHCCCCEEEEECCHHHHHHH
ATSMIPFLQNDDCTRALMGSNMQRQAVPLLMTEAPVIGTGIENKTAVDSGVCVVAEADGV
HHHHHHHHCCCCHHHHHHCCCCCHHCCCEEEECCCEEECCCCCCCCCCCCEEEEEECCCE
VLSSESNKIVIREKDGKAREYKLTKFSRSNQSNCYNQRPIVFKGDEVKAGDVIADGPSTS
EEECCCCEEEEECCCCCCCEEEEEEECCCCCCCCCCCCCEEEECCCCCCCCEEECCCCCC
NGEIALGKNPLIGFMTWEGYNYEDAVLLSERLVRDDVYTSIHIEEYETEARDTKLGPEEI
CCEEEECCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHEEEEEEHHHCHHHHCCCCHHHH
TRDLPSTGSDAVKDLDENGIIRVGAEVRAGDILVGKVTPKGETELTAEERLLRAIFGEKA
HHHCCCCCCHHHHHCCCCCEEEECCEECCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHH
REVRDTSLKVPHGAYGIVVAVKTFTRENGDELSPGVNKSVRIYIAQKRKIGVGDKMAGRH
HHHHHCCEECCCCCEEEEEEEEEHHCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCC
GNKGVVSRVLPVEDMPFLPNGRPLDIVLNPLGVPSRMNIGQVLEIHLSLAAKVLGFNIST
CCCCHHHEECCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCC
PVFDGADENDIMDTLDMANAYANHPFDDEELAAQKAEAEKNGEEYPEDMVTFTAQYKDVL
CCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
NKEVFDYLSEHRDHRAEWKGVPIGRDGKVRLRDGRTGEYFDSPVTIGFMHYLKLHHLVDD
HHHHHHHHHHHCCCHHHCCCCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCC
KIHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEILTVKSDDVVGR
CHHCCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHCCCCCHHHH
VKTYEAIIKGENIPEPGVPESFKVLLKELQSLALDVRVLDQDNNEVRLLESSEYEVTDFK
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHEEEEEEECCCCEEEEEECCCCCHHHHH
KVLDEGNGYRRNSREEEAEYKAGGMSTVTLNEDGTEDAVDSDDGADFDMADDFDDDYGDG
HHHHCCCCCCCCCCHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
NSDEY
CCCCC
>Mature Secondary Structure
MEKNRLRPITSGKAMRMSFSRQKEVLEMPNLIEVQKDSYQWFLNEGLKEVFDDISPIADY
CCCCCCCCCCCCCCEEHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHCC
NGRLSLEFVDFALCEDEVKYSIEECKERDATYAAPLKVTVRLHNKETESISEHEIFMGDL
CCEEEEEEEHHHHHHHHHHHHHHHHHHCCCCEECCEEEEEEEECCCCCCCCCCEEEECCC
PLMTKTGTFVINGAERVIVSQLVRSPGIYYDIQKDKYGKIFLYSCQVIPNRGAWLEYETD
CCEEECCEEEECCHHHHHHHHHHHCCCEEEEECCCCCCEEEEEEEEEECCCCCEEEEECC
ANDIFYVKVDRNKKVPITVLIRALGFGTNAEILDIFGEEPKLLATMEKDTSTNYQEGILE
CCEEEEEEECCCCCCCHHHHHHHHCCCCCCCEEEECCCCCCEEEEECCCCCCCHHHHHHH
LYKKLRPGEPLSVESAEALISGMFFDPRRYDLAHVGRYKFNKKLSFKSRITGQVLAEDVV
HHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCHHHHCHHHCCCCCCHHHHHHHHHHHHHHH
DENGTVIATAGEKLTRESAQAIQDAAVPSVFITVEVKAADGTVSDRVVKILSNRAVDITK
CCCCCEEEECCHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCHHHHHHHHHHCCCEEEEE
WVDISEEEAKELGVTEYVYYPVLAQILAENESLEDIKEAITKNIADLIPKHITVEDILAS
ECCCCHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHH
INYNMHLEYGVGTKDDIDHLGNRRIRAVGELLQNQFRIGISRMERVVRERMSTQDLSGIS
CCCCEEEEECCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCC
PQSLINIKPVTAAIKEFFGSSQLSQFMDQNNPLSEITHKRRLSALGPGGLSRDRAGFEVR
HHHEEECCHHHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEE
DVHYTHYGRMCPIETPEGPNIGLINSLASYARINEYGFVEAPYRIVDKSDPKNPRVTDEV
EEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCE
RYFTADEEDDFHVAQANAEIDENGYFVRNTVSGRYREETSQFDKSQIDLMDVSPKMVFSV
EEEECCCCCCEEEEECCCEECCCCCEEEECCCCCHHHHHHHHCCCCEEEEECCHHHHHHH
ATSMIPFLQNDDCTRALMGSNMQRQAVPLLMTEAPVIGTGIENKTAVDSGVCVVAEADGV
HHHHHHHHCCCCHHHHHHCCCCCHHCCCEEEECCCEEECCCCCCCCCCCCEEEEEECCCE
VLSSESNKIVIREKDGKAREYKLTKFSRSNQSNCYNQRPIVFKGDEVKAGDVIADGPSTS
EEECCCCEEEEECCCCCCCEEEEEEECCCCCCCCCCCCCEEEECCCCCCCCEEECCCCCC
NGEIALGKNPLIGFMTWEGYNYEDAVLLSERLVRDDVYTSIHIEEYETEARDTKLGPEEI
CCEEEECCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHEEEEEEHHHCHHHHCCCCHHHH
TRDLPSTGSDAVKDLDENGIIRVGAEVRAGDILVGKVTPKGETELTAEERLLRAIFGEKA
HHHCCCCCCHHHHHCCCCCEEEECCEECCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHH
REVRDTSLKVPHGAYGIVVAVKTFTRENGDELSPGVNKSVRIYIAQKRKIGVGDKMAGRH
HHHHHCCEECCCCCEEEEEEEEEHHCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCC
GNKGVVSRVLPVEDMPFLPNGRPLDIVLNPLGVPSRMNIGQVLEIHLSLAAKVLGFNIST
CCCCHHHEECCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCC
PVFDGADENDIMDTLDMANAYANHPFDDEELAAQKAEAEKNGEEYPEDMVTFTAQYKDVL
CCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
NKEVFDYLSEHRDHRAEWKGVPIGRDGKVRLRDGRTGEYFDSPVTIGFMHYLKLHHLVDD
HHHHHHHHHHHCCCHHHCCCCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCC
KIHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEILTVKSDDVVGR
CHHCCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHCCCCCHHHH
VKTYEAIIKGENIPEPGVPESFKVLLKELQSLALDVRVLDQDNNEVRLLESSEYEVTDFK
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHEEEEEEECCCCEEEEEECCCCCHHHHH
KVLDEGNGYRRNSREEEAEYKAGGMSTVTLNEDGTEDAVDSDDGADFDMADDFDDDYGDG
HHHHCCCCCCCCCCHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
NSDEY
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA