Click here to switch to the map view.

The map label for this gene is mnaA [H]

Identifier: 238916215

GI number: 238916215

Start: 277612

End: 278712

Strand: Direct

Name: mnaA [H]

Synonym: EUBELI_00249

Alternate gene names: 238916215

Gene position: 277612-278712 (Clockwise)

Preceding gene: 238916214

Following gene: 238916216

Centisome position: 12.95

GC content: 31.61

Gene sequence:

>1101_bases
ATGAAGGTAATGTCAATATTTGGAACAAGACCCGAAGCCATAAAAATGTGTCCGGTTATAAAAGAACTTGAGAGTAGAGA
AAAAATAAAAAGTGTTGTATGTTTAACAGGACAACATAAAGAGATGCTTCAGCCTGTTATGAAATTGTTTGAAATAAAAG
AAGATTATAATCTTCGGATAATGACAGAAAATCAATCATTATCTAGTATTACATGTAAAATTTTGGATATGCTGGAAGAA
CTATTAAATAAAGAAAAACCAGATATGATACTTGTTCATGGCGATACCACGAGTGCTTATGCAGCAGCATTATCAGCATT
TTATCATAATATTCCTGTAGGTCATGTGGAAGCAGGACTTAGAACATATAATATGCATTCTCCTTTTCCGGAAGAATTTA
ATAGACAATCAATTGATTTGGTATCTGATATATTGTTTGCTCCAACTCAATATGCTAAAGATATGTTGCTATCAGAGAAA
AAAGGTGAAAATAAAATATTTGTTACAGGGAATACGGTAATTGATGCTTTAAAGACAACTGTTTGTAAAAGCTATAATAT
TACGGAATGTTGCGAAGATGATAAATTGATTTTACTTACTGCACATAGACGTGAAAATATAGGGGAACCAATGAAAAATA
TATTTTCAGCAGTAAACAAGATAACAGAGGATTATCCAGAAATTAAGGTGATTTATCCAGTTCATAAAAATCCAAAGATT
AGAGAGATTGCAAATCAATTTTTTGCTAATAATAGCAGGGTGAAAATGATCGAACCAATGGATGTTTACGACTTTCATAA
TGTCATGAACAAAAGTTATTTGATTTTAACAGATAGTGGTGGAATTCAAGAAGAAGCAACATCTCTTGGAAAACCAGTTC
TCATATTGAGAGATACTACAGAAAGACCAGAAGGAGTTGCAGCGGGAACATTAAAAATTGTCGGAACCCAGACTGAGAAT
ATATATTTAGAAACAAAGAGATTATTAACAGATAAGGATGAATATAACAGAATGAGCAAATCTGTAAATCCATATGGAGA
TGGAAACGCATCAAAAACAATTGTTGATATAATCGAAAGATATTTTGAGGGGAAGCTATAA

Upstream 100 bases:

>100_bases
TTATATTGTGATAATGTTGAAGTGAAAAAAGGACTTAAATGTAAAGGAGTGTACAATTCTAATCTGTTTACTGCTTGGAT
TGGAACAGTAAGGTGAGAAC

Downstream 100 bases:

>100_bases
TGCCAAAAGTGTCCGTTATTTTACCTACATACAATGGAGAAAAATATATAAGAGAAGCTATTGATAGTATTATAAATCAA
ACTTTTACAGATTGGGAATT

Product: UDP-N-acetylglucosamine 2-epimerase

Products: NA

Alternate protein names: UDP-GlcNAc-2-epimerase [H]

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MKVMSIFGTRPEAIKMCPVIKELESREKIKSVVCLTGQHKEMLQPVMKLFEIKEDYNLRIMTENQSLSSITCKILDMLEE
LLNKEKPDMILVHGDTTSAYAAALSAFYHNIPVGHVEAGLRTYNMHSPFPEEFNRQSIDLVSDILFAPTQYAKDMLLSEK
KGENKIFVTGNTVIDALKTTVCKSYNITECCEDDKLILLTAHRRENIGEPMKNIFSAVNKITEDYPEIKVIYPVHKNPKI
REIANQFFANNSRVKMIEPMDVYDFHNVMNKSYLILTDSGGIQEEATSLGKPVLILRDTTERPEGVAAGTLKIVGTQTEN
IYLETKRLLTDKDEYNRMSKSVNPYGDGNASKTIVDIIERYFEGKL

Sequences:

>Translated_366_residues
MKVMSIFGTRPEAIKMCPVIKELESREKIKSVVCLTGQHKEMLQPVMKLFEIKEDYNLRIMTENQSLSSITCKILDMLEE
LLNKEKPDMILVHGDTTSAYAAALSAFYHNIPVGHVEAGLRTYNMHSPFPEEFNRQSIDLVSDILFAPTQYAKDMLLSEK
KGENKIFVTGNTVIDALKTTVCKSYNITECCEDDKLILLTAHRRENIGEPMKNIFSAVNKITEDYPEIKVIYPVHKNPKI
REIANQFFANNSRVKMIEPMDVYDFHNVMNKSYLILTDSGGIQEEATSLGKPVLILRDTTERPEGVAAGTLKIVGTQTEN
IYLETKRLLTDKDEYNRMSKSVNPYGDGNASKTIVDIIERYFEGKL
>Mature_366_residues
MKVMSIFGTRPEAIKMCPVIKELESREKIKSVVCLTGQHKEMLQPVMKLFEIKEDYNLRIMTENQSLSSITCKILDMLEE
LLNKEKPDMILVHGDTTSAYAAALSAFYHNIPVGHVEAGLRTYNMHSPFPEEFNRQSIDLVSDILFAPTQYAKDMLLSEK
KGENKIFVTGNTVIDALKTTVCKSYNITECCEDDKLILLTAHRRENIGEPMKNIFSAVNKITEDYPEIKVIYPVHKNPKI
REIANQFFANNSRVKMIEPMDVYDFHNVMNKSYLILTDSGGIQEEATSLGKPVLILRDTTERPEGVAAGTLKIVGTQTEN
IYLETKRLLTDKDEYNRMSKSVNPYGDGNASKTIVDIIERYFEGKL

Specific function: Catalyzes the conversion of UDP-N-acetylglucosamine into UDP-N-acetylmannosamine, a precursor of the teichoic acid linkage unit [H]

COG id: COG0381

COG function: function code M; UDP-N-acetylglucosamine 2-epimerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-N-acetylglucosamine 2-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI48994967, Length=372, Percent_Identity=47.3118279569892, Blast_Score=347, Evalue=8e-97,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003331 [H]

Pfam domain/function: PF02350 Epimerase_2 [H]

EC number: =5.1.3.14 [H]

Molecular weight: Translated: 41593; Mature: 41593

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVMSIFGTRPEAIKMCPVIKELESREKIKSVVCLTGQHKEMLQPVMKLFEIKEDYNLRI
CCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEE
MTENQSLSSITCKILDMLEELLNKEKPDMILVHGDTTSAYAAALSAFYHNIPVGHVEAGL
EECCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCHHHHHCC
RTYNMHSPFPEEFNRQSIDLVSDILFAPTQYAKDMLLSEKKGENKIFVTGNTVIDALKTT
EEECCCCCCCHHHCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHH
VCKSYNITECCEDDKLILLTAHRRENIGEPMKNIFSAVNKITEDYPEIKVIYPVHKNPKI
HHCCCCCHHHCCCCCEEEEEECCHHCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCH
REIANQFFANNSRVKMIEPMDVYDFHNVMNKSYLILTDSGGIQEEATSLGKPVLILRDTT
HHHHHHHHCCCCCEEEECCCCHHHHHHHHCCCEEEEECCCCCHHHHHHCCCCEEEEECCC
ERPEGVAAGTLKIVGTQTENIYLETKRLLTDKDEYNRMSKSVNPYGDGNASKTIVDIIER
CCCCCCEECEEEEEECCCCEEEEEHHHHHCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHH
YFEGKL
HHCCCC
>Mature Secondary Structure
MKVMSIFGTRPEAIKMCPVIKELESREKIKSVVCLTGQHKEMLQPVMKLFEIKEDYNLRI
CCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEE
MTENQSLSSITCKILDMLEELLNKEKPDMILVHGDTTSAYAAALSAFYHNIPVGHVEAGL
EECCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCHHHHHCC
RTYNMHSPFPEEFNRQSIDLVSDILFAPTQYAKDMLLSEKKGENKIFVTGNTVIDALKTT
EEECCCCCCCHHHCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHH
VCKSYNITECCEDDKLILLTAHRRENIGEPMKNIFSAVNKITEDYPEIKVIYPVHKNPKI
HHCCCCCHHHCCCCCEEEEEECCHHCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCH
REIANQFFANNSRVKMIEPMDVYDFHNVMNKSYLILTDSGGIQEEATSLGKPVLILRDTT
HHHHHHHHCCCCCEEEECCCCHHHHHHHHCCCEEEEECCCCCHHHHHHCCCCEEEEECCC
ERPEGVAAGTLKIVGTQTENIYLETKRLLTDKDEYNRMSKSVNPYGDGNASKTIVDIIER
CCCCCCEECEEEEEECCCCEEEEEHHHHHCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHH
YFEGKL
HHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8126437; 12107153; 9384377 [H]