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The map label for this gene is mbl [H]

Identifier: 238916188

GI number: 238916188

Start: 248917

End: 249915

Strand: Direct

Name: mbl [H]

Synonym: EUBELI_00222

Alternate gene names: 238916188

Gene position: 248917-249915 (Clockwise)

Preceding gene: 238916187

Following gene: 238916189

Centisome position: 11.61

GC content: 41.44

Gene sequence:

>999_bases
ATGTTATCAACAGATATTGGTATAGATTTAGGTACTGCAAGTATTCTTGTGTACATCAGAGGCAAAGGAGTTGTTCTTAA
AGAGCCTTCAGTTGTTGCATTTGACAGGGATACTAATAAGATTAAGGCTATCGGTGAGGAAGCAAGACTGATGCTTGGTA
GAACACCAGGTAACATCGTTGCTGTAAGACCTCTTCGTCAGGGTGTTATCTCTGATTACACTGTAACTGAGAAGATGCTT
AAGTACTTTATCCAGAAGGCTATCGGCAAGAGAATGCTTAAGAAGCCTAGAATCAGTGTATGCGTACCTTCAGGTGTTAC
TGAGGTTGAGAAGAAGGCGGTTGAGGATGCTACTCTTCAGGCAGGTGCAAGAGAGGTTGCTATTATTGAAGAGCCTATCG
CAGCAGCTATCGGTGCAGGTATTGATATTTCAAGACCATGTGGTAATATGATTGTTGATATCGGTGGTGGTACAACTGAT
ATCGCTGTTATCTCTTTAGGAGGAACTGTTGTAAGTACTTCTATTAAGATTGCCGGTGATGATTTTGATGAAGCTATCGT
AAGATACATGAGAAAGAAGCATAATCTTCTTATCGGTGAAAGAACCGCAGAAGATATTAAGATAAAGGTTGGTTCTGCTT
ATCCTAAGGCAGAAGTCACAACTATGAATGTACGAGGAAGAAACCTTGTAACAGGTCTTCCTAAGACTGTAGAGGTAAGC
TCAGAGGAGACAGAGGAAGCTTTAAGAGAGGCAACTTCACAGATTGTTGAAGCTGTTCACAGCGTTCTTGAGAAGACTCC
ACCAGAACTTGCATCTGATATTGCAGACAGAGGAATCGTCCTTACAGGAGGCGGAAGTCTTCTTTCAGGACTTGAGGATT
TAATTGAAGCCAAGACAGGAATTAATACTATGACAGCCGAAGATCCAATGACATGTGTTGCTATTGGTACAGGTAAGTTT
ATTGAGTTCCTTGCAGGCTACAGAGACGAAGTTAAGTAA

Upstream 100 bases:

>100_bases
ATGGGCACACATGGCTTCTAATGACTTTTGAGTTTATGTTTTATCTGAATATATCGGACAGACAGAGGTCCGCATTGTTT
TATAAGAAAGGGGAATTATC

Downstream 100 bases:

>100_bases
CCTGGAACATTTTTAATAAGATTATTACAAATGTTTCTTAACATTCTGGCAGAATGGACAATTTTTATGCCGGAAGAATA
TATTATCAAGAAAGAGGCGG

Product: rod shape-determining protein MreB

Products: NA

Alternate protein names: Protein mbl [H]

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MLSTDIGIDLGTASILVYIRGKGVVLKEPSVVAFDRDTNKIKAIGEEARLMLGRTPGNIVAVRPLRQGVISDYTVTEKML
KYFIQKAIGKRMLKKPRISVCVPSGVTEVEKKAVEDATLQAGAREVAIIEEPIAAAIGAGIDISRPCGNMIVDIGGGTTD
IAVISLGGTVVSTSIKIAGDDFDEAIVRYMRKKHNLLIGERTAEDIKIKVGSAYPKAEVTTMNVRGRNLVTGLPKTVEVS
SEETEEALREATSQIVEAVHSVLEKTPPELASDIADRGIVLTGGGSLLSGLEDLIEAKTGINTMTAEDPMTCVAIGTGKF
IEFLAGYRDEVK

Sequences:

>Translated_332_residues
MLSTDIGIDLGTASILVYIRGKGVVLKEPSVVAFDRDTNKIKAIGEEARLMLGRTPGNIVAVRPLRQGVISDYTVTEKML
KYFIQKAIGKRMLKKPRISVCVPSGVTEVEKKAVEDATLQAGAREVAIIEEPIAAAIGAGIDISRPCGNMIVDIGGGTTD
IAVISLGGTVVSTSIKIAGDDFDEAIVRYMRKKHNLLIGERTAEDIKIKVGSAYPKAEVTTMNVRGRNLVTGLPKTVEVS
SEETEEALREATSQIVEAVHSVLEKTPPELASDIADRGIVLTGGGSLLSGLEDLIEAKTGINTMTAEDPMTCVAIGTGKF
IEFLAGYRDEVK
>Mature_332_residues
MLSTDIGIDLGTASILVYIRGKGVVLKEPSVVAFDRDTNKIKAIGEEARLMLGRTPGNIVAVRPLRQGVISDYTVTEKML
KYFIQKAIGKRMLKKPRISVCVPSGVTEVEKKAVEDATLQAGAREVAIIEEPIAAAIGAGIDISRPCGNMIVDIGGGTTD
IAVISLGGTVVSTSIKIAGDDFDEAIVRYMRKKHNLLIGERTAEDIKIKVGSAYPKAEVTTMNVRGRNLVTGLPKTVEVS
SEETEEALREATSQIVEAVHSVLEKTPPELASDIADRGIVLTGGGSLLSGLEDLIEAKTGINTMTAEDPMTCVAIGTGKF
IEFLAGYRDEVK

Specific function: Not essential for cell viability or sporulation [H]

COG id: COG1077

COG function: function code D; Actin-like ATPase involved in cell morphogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Homo sapiens, GI16507237, Length=397, Percent_Identity=26.9521410579345, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI87082236, Length=329, Percent_Identity=54.1033434650456, Blast_Score=359, Evalue=1e-100,
Organism=Escherichia coli, GI1788875, Length=271, Percent_Identity=23.9852398523985, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17507981, Length=393, Percent_Identity=26.7175572519084, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17534015, Length=388, Percent_Identity=23.4536082474227, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17534013, Length=388, Percent_Identity=23.4536082474227, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6322426, Length=377, Percent_Identity=26.790450928382, Blast_Score=74, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004753 [H]

Pfam domain/function: PF06723 MreB_Mbl [H]

EC number: NA

Molecular weight: Translated: 35367; Mature: 35367

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSTDIGIDLGTASILVYIRGKGVVLKEPSVVAFDRDTNKIKAIGEEARLMLGRTPGNIV
CCCCCCCCEECCEEEEEEECCCEEEEECCCEEEEECCCCHHHHHCHHHHEEEECCCCCEE
AVRPLRQGVISDYTVTEKMLKYFIQKAIGKRMLKKPRISVCVPSGVTEVEKKAVEDATLQ
EECHHHHCHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHH
AGAREVAIIEEPIAAAIGAGIDISRPCGNMIVDIGGGTTDIAVISLGGTVVSTSIKIAGD
CCCCEEEEEHHHHHHHHCCCCCCCCCCCCEEEECCCCCCEEEEEEECCEEEEEEEEEECC
DFDEAIVRYMRKKHNLLIGERTAEDIKIKVGSAYPKAEVTTMNVRGRNLVTGLPKTVEVS
CHHHHHHHHHHHHCCEEEECCCCCEEEEEECCCCCCCEEEEEEECCCCCCCCCCCEEECC
SEETEEALREATSQIVEAVHSVLEKTPPELASDIADRGIVLTGGGSLLSGLEDLIEAKTG
CHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEEECCCHHHHHHHHHHHHHCC
INTMTAEDPMTCVAIGTGKFIEFLAGYRDEVK
CCCEECCCCEEEEEECCHHHHHHHHCHHHCCC
>Mature Secondary Structure
MLSTDIGIDLGTASILVYIRGKGVVLKEPSVVAFDRDTNKIKAIGEEARLMLGRTPGNIV
CCCCCCCCEECCEEEEEEECCCEEEEECCCEEEEECCCCHHHHHCHHHHEEEECCCCCEE
AVRPLRQGVISDYTVTEKMLKYFIQKAIGKRMLKKPRISVCVPSGVTEVEKKAVEDATLQ
EECHHHHCHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHH
AGAREVAIIEEPIAAAIGAGIDISRPCGNMIVDIGGGTTDIAVISLGGTVVSTSIKIAGD
CCCCEEEEEHHHHHHHHCCCCCCCCCCCCEEEECCCCCCEEEEEEECCEEEEEEEEEECC
DFDEAIVRYMRKKHNLLIGERTAEDIKIKVGSAYPKAEVTTMNVRGRNLVTGLPKTVEVS
CHHHHHHHHHHHHCCEEEECCCCCEEEEEECCCCCCCEEEEEEECCCCCCCCCCCEEECC
SEETEEALREATSQIVEAVHSVLEKTPPELASDIADRGIVLTGGGSLLSGLEDLIEAKTG
CHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEEECCCHHHHHHHHHHHHHCC
INTMTAEDPMTCVAIGTGKFIEFLAGYRDEVK
CCCEECCCCEEEEEECCHHHHHHHHCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7836311; 9384377; 10568751; 9353933 [H]