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The map label for this gene is mta [H]

Identifier: 238916055

GI number: 238916055

Start: 94979

End: 96223

Strand: Direct

Name: mta [H]

Synonym: EUBELI_00088

Alternate gene names: 238916055

Gene position: 94979-96223 (Clockwise)

Preceding gene: 238916050

Following gene: 238916056

Centisome position: 4.43

GC content: 36.06

Gene sequence:

>1245_bases
ATGCATAAAGAGGGATATTATTCTTCAGGGGAATTTGCGAAGAAAGCAAATGTTTCGGTAAGGACTATAAGATATTATGA
CCAGCAGAACATATTAAAGCCATCACTTCTTACTGATGAGGGAGTGAGATTTTATACGGATTCAGATTTTACAAGGTTAC
AGCAGATATTATTGCTTAAATATCTTGGATTTACACTGGATGATATAAGAAATATGACAATTGGTGATTCAGATTATCAT
GTGCTAAAGAATTCACTTGAACTTCAAAAGCGAATGATACAGGACAAGATTGCACAGATGCAGCTTGTATGTAAAGCTAT
TGAAGAAACAGAAGACTCTATTAAAGAGGGAAAAGGAGTTGACTGGAGTAATATGCTGGAGATTATCCATCTTACTAATA
TGGAAGACAGCATGAAGAATCAGTACATTAATGCTGGAAATATATCTGCAAGAATTAATCTTCATAACAGGTTTTCAGTT
AATAAACAGGGATGGTTTCCGTGGGTATATGAGCAGTGTGGTATTGTTAAGGGGATGAGAATTCTTGAGATTGGGTGTGG
TGATGGAACATTGTGGGTTGACAATATAGGTCAGCTTGCCATGACAGGAAAGAGAAATGAATTTTCAGGGAAGAAAAAAA
ACATATATATAGAGCTTACAGATATATCAGAAGGCATGATAAGTGATGCGAGAAGAAATATAAAAAAAGCAACAGAGAGC
TGGAAGGAAAGAGATATTGATGTGTCATTCAGGTTCAGAGTGGCTTCATGCGAAAAGACAGGGGCAAAAGATGAATCGTA
TGATCTGGTGATTGCTAATCATGTGCTGTTTTATTGTAAAAATGTCAATAAGGCACTTGATGAAATTGTGAGGGTGTTAA
AGCCTGGAGGAGTGCTTGTGTGCAGTACATATGGCAGCAGGCATATGCAGGAGATAAGCCGCCTTGTGTCGGGATATGAT
AAGAGAATTGCACTTGAAGCAGATAAGCTTTTTGAAAAATTCGGACTTGATAATGGAGATAAGATATTAAAAAAACATTT
TTCAGATGTTGAGAGAAGAGATTATAAAGATGCGCTTGTTGTTGATGAAGCAGAACCGCTGGTAGATTATATACTATCAT
GTCATGGCAATCAGAAAGAGTACCTTGTGGATAAGTATACAGATTTTAAAAAATATGTAGAGAAAAAGCTTGTGAAACCT
ATGACAATAACCAAAGAGGCTGGTGTATTTGTGTGTAGAAAATAA

Upstream 100 bases:

>100_bases
TTAATTTTCAAGTAGACATTTTTTAAGTCATGTATATAATAAAAGGTGACGCAGCGTCACCTTCAAGTGTTTTTTGAAAA
ATTTTTACAAGGAGTAATAT

Downstream 100 bases:

>100_bases
TGTATAGCAATTATATCTATAATATGGTAAAATCAAAAGAAACATGTTTTGTTACAGGGATAGTTTGAACATGCATATTA
TGGAAATACTCTGATAGAAT

Product: 7-cyano-7-deazaguanine reductase

Products: NA

Alternate protein names: Multidrug transporter activation protein [H]

Number of amino acids: Translated: 414; Mature: 414

Protein sequence:

>414_residues
MHKEGYYSSGEFAKKANVSVRTIRYYDQQNILKPSLLTDEGVRFYTDSDFTRLQQILLLKYLGFTLDDIRNMTIGDSDYH
VLKNSLELQKRMIQDKIAQMQLVCKAIEETEDSIKEGKGVDWSNMLEIIHLTNMEDSMKNQYINAGNISARINLHNRFSV
NKQGWFPWVYEQCGIVKGMRILEIGCGDGTLWVDNIGQLAMTGKRNEFSGKKKNIYIELTDISEGMISDARRNIKKATES
WKERDIDVSFRFRVASCEKTGAKDESYDLVIANHVLFYCKNVNKALDEIVRVLKPGGVLVCSTYGSRHMQEISRLVSGYD
KRIALEADKLFEKFGLDNGDKILKKHFSDVERRDYKDALVVDEAEPLVDYILSCHGNQKEYLVDKYTDFKKYVEKKLVKP
MTITKEAGVFVCRK

Sequences:

>Translated_414_residues
MHKEGYYSSGEFAKKANVSVRTIRYYDQQNILKPSLLTDEGVRFYTDSDFTRLQQILLLKYLGFTLDDIRNMTIGDSDYH
VLKNSLELQKRMIQDKIAQMQLVCKAIEETEDSIKEGKGVDWSNMLEIIHLTNMEDSMKNQYINAGNISARINLHNRFSV
NKQGWFPWVYEQCGIVKGMRILEIGCGDGTLWVDNIGQLAMTGKRNEFSGKKKNIYIELTDISEGMISDARRNIKKATES
WKERDIDVSFRFRVASCEKTGAKDESYDLVIANHVLFYCKNVNKALDEIVRVLKPGGVLVCSTYGSRHMQEISRLVSGYD
KRIALEADKLFEKFGLDNGDKILKKHFSDVERRDYKDALVVDEAEPLVDYILSCHGNQKEYLVDKYTDFKKYVEKKLVKP
MTITKEAGVFVCRK
>Mature_414_residues
MHKEGYYSSGEFAKKANVSVRTIRYYDQQNILKPSLLTDEGVRFYTDSDFTRLQQILLLKYLGFTLDDIRNMTIGDSDYH
VLKNSLELQKRMIQDKIAQMQLVCKAIEETEDSIKEGKGVDWSNMLEIIHLTNMEDSMKNQYINAGNISARINLHNRFSV
NKQGWFPWVYEQCGIVKGMRILEIGCGDGTLWVDNIGQLAMTGKRNEFSGKKKNIYIELTDISEGMISDARRNIKKATES
WKERDIDVSFRFRVASCEKTGAKDESYDLVIANHVLFYCKNVNKALDEIVRVLKPGGVLVCSTYGSRHMQEISRLVSGYD
KRIALEADKLFEKFGLDNGDKILKKHFSDVERRDYKDALVVDEAEPLVDYILSCHGNQKEYLVDKYTDFKKYVEKKLVKP
MTITKEAGVFVCRK

Specific function: Global transcriptional regulator that activates transcription of bmr and blt by binding directly to their promoter. Stimulates also the expression of the mta gene itself, ydfK and ymfE [H]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789687, Length=112, Percent_Identity=34.8214285714286, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR012925
- InterPro:   IPR015358 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind; PF07739 TipAS [H]

EC number: NA

Molecular weight: Translated: 47735; Mature: 47735

Theoretical pI: Translated: 8.18; Mature: 8.18

Prosite motif: PS00552 HTH_MERR_1 ; PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHKEGYYSSGEFAKKANVSVRTIRYYDQQNILKPSLLTDEGVRFYTDSDFTRLQQILLLK
CCCCCCCCCCCCHHHCCCEEEEEEEECCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHH
YLGFTLDDIRNMTIGDSDYHVLKNSLELQKRMIQDKIAQMQLVCKAIEETEDSIKEGKGV
HHCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DWSNMLEIIHLTNMEDSMKNQYINAGNISARINLHNRFSVNKQGWFPWVYEQCGIVKGMR
CHHHHHHHHHCCCCCHHHHHCCCCCCCEEEEEEECCEEECCCCCCCCHHHHHCCHHCCCE
ILEIGCGDGTLWVDNIGQLAMTGKRNEFSGKKKNIYIELTDISEGMISDARRNIKKATES
EEEEECCCCEEECCCCCCEEECCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHH
WKERDIDVSFRFRVASCEKTGAKDESYDLVIANHVLFYCKNVNKALDEIVRVLKPGGVLV
HHHCCCCEEEEEEEECCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
CSTYGSRHMQEISRLVSGYDKRIALEADKLFEKFGLDNGDKILKKHFSDVERRDYKDALV
EECCCHHHHHHHHHHHCCCCCEEEECHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEE
VDEAEPLVDYILSCHGNQKEYLVDKYTDFKKYVEKKLVKPMTITKEAGVFVCRK
ECCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEECCCCEEEECC
>Mature Secondary Structure
MHKEGYYSSGEFAKKANVSVRTIRYYDQQNILKPSLLTDEGVRFYTDSDFTRLQQILLLK
CCCCCCCCCCCCHHHCCCEEEEEEEECCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHH
YLGFTLDDIRNMTIGDSDYHVLKNSLELQKRMIQDKIAQMQLVCKAIEETEDSIKEGKGV
HHCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DWSNMLEIIHLTNMEDSMKNQYINAGNISARINLHNRFSVNKQGWFPWVYEQCGIVKGMR
CHHHHHHHHHCCCCCHHHHHCCCCCCCEEEEEEECCEEECCCCCCCCHHHHHCCHHCCCE
ILEIGCGDGTLWVDNIGQLAMTGKRNEFSGKKKNIYIELTDISEGMISDARRNIKKATES
EEEEECCCCEEECCCCCCEEECCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHH
WKERDIDVSFRFRVASCEKTGAKDESYDLVIANHVLFYCKNVNKALDEIVRVLKPGGVLV
HHHCCCCEEEEEEEECCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
CSTYGSRHMQEISRLVSGYDKRIALEADKLFEKFGLDNGDKILKKHFSDVERRDYKDALV
EECCCHHHHHHHHHHHCCCCCEEEECHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEE
VDEAEPLVDYILSCHGNQKEYLVDKYTDFKKYVEKKLVKPMTITKEAGVFVCRK
ECCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEECCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9150240; 9384377 [H]