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The map label for this gene is speA [H]

Identifier: 238915990

GI number: 238915990

Start: 22425

End: 23828

Strand: Direct

Name: speA [H]

Synonym: EUBELI_00023

Alternate gene names: 238915990

Gene position: 22425-23828 (Clockwise)

Preceding gene: 238915989

Following gene: 238915991

Centisome position: 1.05

GC content: 36.82

Gene sequence:

>1404_bases
ATGGGAAATATAGATATTCTGGAAAAACTTGAAGAGTATTCAAAAGCTGGTTATGTGCCGATGCATATGCCGGGAGGAAA
GCGCAATACTGAATATGCAAGTACTTCAGAACTTGATATTACCGAGATTGACGGATTTGATAATATGCATAATGCGGATG
GTATTATTAAAAATGCGTCTGACAGGGCAGCAAAATTGTATGGAGCAGATAAAACACTGATGCTTGTAAATGGAAGTACA
GCAGGAATATTATCAGCTATATGTGGTGCGACGAAAAGAAAAGGAAAGATTATCGTTGCAAGAAACTGTCATGTGTCAGT
GTACAATGCATTGATTATGGCACAGTTAGAGCCAGTATATGTTATACCGGAGGTTGATAATGATACAGGAATATACAGAG
GACTATCATTAGAACAGATTAGAAAATGTGTTGAAAATAACAGGGATGCACAGGCGGTTATTATAACTTCTCCGACTTAT
GAAGGTGTTGTGTCAGAGGTAAGGGAGATTGCCAGTTATCTGCATGAAAAAGGAATACCACTTATAGTTGACGAAGCGCA
TGGGGCACATTTTGAATTCAGTGAGGAATTTCCAGAGTCGGCAGTAAAAGCTGGGGCTGACATTGTAATTAACAGTATTC
ATAAAACATTACCGGCACTTACACAGACTGCACTTCTACATATTTCTGGAAATTATGTAGATTATGATAAAGTGGAAAGA
TTTTGGAATATATATCAGACAACCAGCCCCTCATATATTCTTATGGCGAGTATTGACAGGTGTATGAGAATTATTGAAGA
ACAGGGAGATTATATTTTTAAGGATTATATCAAAAGACTTAAGAATTTAAGAGAAAATATTGCAAAACTTAATAATATAA
GATTGATGGATAGTGATGATATTTCTAAGATTATTCTTATATGTGATGATGGAAAGTACCTGTATGACAGGTTATTGGAT
GAATATAAGGTGCAGCTTGAGATGGCATCATTTAAATATGTTATTGCAATGACTTCAGTTGCTGATAAACAGGAGTATTA
TGACAGATTTCTTAGTGCATTGAAGGAGATTGATGAAAGCTGGAAAGTTGAAAGCAAAGACAGTGAAAATGATGTAGGGG
AAAGCTTAGGGTATGCGATTAACAACAAGCCGGAAGTATGTATGTGTCCGGCAGATGCAATTGATTTAATGGATGAAAAT
GGATATGAAGATTTATCTGTTAATTCACCTGATATATGTGGTAGAATAAGTATGTCATCGGTTCTTATATACCCACCGGG
AATGCCTGTTGTTAATGTAGGCGAGCGGATTACCGGTGATGTATGCAGAATTATTAAGAGTGCGATAAATGCCGGGCTGG
AAGTACCCGGTCTTAAGGAAGGAAAGATAAGATGCCTGAGATAG

Upstream 100 bases:

>100_bases
CTTATGATATTAAGTATGAAGTTACAGATGCAATTGGAAGCCATGATGAAGTAACAGTAAAGCTTATGGTTACAGAATAA
GAGATAATGGAGTTGTATTG

Downstream 100 bases:

>100_bases
CATTTATTATGGGAAAAAGCGCGTCCGGCAAGGATAAAATATATAAAAACCTAATTGAAGATGAAAGTCTGAAGCTTAAT
ACTGTTATATTGTATACAAC

Product: lysine decarboxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 467; Mature: 466

Protein sequence:

>467_residues
MGNIDILEKLEEYSKAGYVPMHMPGGKRNTEYASTSELDITEIDGFDNMHNADGIIKNASDRAAKLYGADKTLMLVNGST
AGILSAICGATKRKGKIIVARNCHVSVYNALIMAQLEPVYVIPEVDNDTGIYRGLSLEQIRKCVENNRDAQAVIITSPTY
EGVVSEVREIASYLHEKGIPLIVDEAHGAHFEFSEEFPESAVKAGADIVINSIHKTLPALTQTALLHISGNYVDYDKVER
FWNIYQTTSPSYILMASIDRCMRIIEEQGDYIFKDYIKRLKNLRENIAKLNNIRLMDSDDISKIILICDDGKYLYDRLLD
EYKVQLEMASFKYVIAMTSVADKQEYYDRFLSALKEIDESWKVESKDSENDVGESLGYAINNKPEVCMCPADAIDLMDEN
GYEDLSVNSPDICGRISMSSVLIYPPGMPVVNVGERITGDVCRIIKSAINAGLEVPGLKEGKIRCLR

Sequences:

>Translated_467_residues
MGNIDILEKLEEYSKAGYVPMHMPGGKRNTEYASTSELDITEIDGFDNMHNADGIIKNASDRAAKLYGADKTLMLVNGST
AGILSAICGATKRKGKIIVARNCHVSVYNALIMAQLEPVYVIPEVDNDTGIYRGLSLEQIRKCVENNRDAQAVIITSPTY
EGVVSEVREIASYLHEKGIPLIVDEAHGAHFEFSEEFPESAVKAGADIVINSIHKTLPALTQTALLHISGNYVDYDKVER
FWNIYQTTSPSYILMASIDRCMRIIEEQGDYIFKDYIKRLKNLRENIAKLNNIRLMDSDDISKIILICDDGKYLYDRLLD
EYKVQLEMASFKYVIAMTSVADKQEYYDRFLSALKEIDESWKVESKDSENDVGESLGYAINNKPEVCMCPADAIDLMDEN
GYEDLSVNSPDICGRISMSSVLIYPPGMPVVNVGERITGDVCRIIKSAINAGLEVPGLKEGKIRCLR
>Mature_466_residues
GNIDILEKLEEYSKAGYVPMHMPGGKRNTEYASTSELDITEIDGFDNMHNADGIIKNASDRAAKLYGADKTLMLVNGSTA
GILSAICGATKRKGKIIVARNCHVSVYNALIMAQLEPVYVIPEVDNDTGIYRGLSLEQIRKCVENNRDAQAVIITSPTYE
GVVSEVREIASYLHEKGIPLIVDEAHGAHFEFSEEFPESAVKAGADIVINSIHKTLPALTQTALLHISGNYVDYDKVERF
WNIYQTTSPSYILMASIDRCMRIIEEQGDYIFKDYIKRLKNLRENIAKLNNIRLMDSDDISKIILICDDGKYLYDRLLDE
YKVQLEMASFKYVIAMTSVADKQEYYDRFLSALKEIDESWKVESKDSENDVGESLGYAINNKPEVCMCPADAIDLMDENG
YEDLSVNSPDICGRISMSSVLIYPPGMPVVNVGERITGDVCRIIKSAINAGLEVPGLKEGKIRCLR

Specific function: Catalyzes the formation of agmatine from arginine [H]

COG id: COG1982

COG function: function code E; Arginine/lysine/ornithine decarboxylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1790573, Length=257, Percent_Identity=26.0700389105058, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1786384, Length=250, Percent_Identity=25.6, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI221142684, Length=261, Percent_Identity=22.2222222222222, Blast_Score=73, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000310
- InterPro:   IPR008286
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF01276 OKR_DC_1; PF03711 OKR_DC_1_C [H]

EC number: =4.1.1.19 [H]

Molecular weight: Translated: 52141; Mature: 52010

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGNIDILEKLEEYSKAGYVPMHMPGGKRNTEYASTSELDITEIDGFDNMHNADGIIKNAS
CCCHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCEECCC
DRAAKLYGADKTLMLVNGSTAGILSAICGATKRKGKIIVARNCHVSVYNALIMAQLEPVY
HHHHHHCCCCCEEEEECCCHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHCCCCEE
VIPEVDNDTGIYRGLSLEQIRKCVENNRDAQAVIITSPTYEGVVSEVREIASYLHEKGIP
EEEECCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCC
LIVDEAHGAHFEFSEEFPESAVKAGADIVINSIHKTLPALTQTALLHISGNYVDYDKVER
EEEECCCCCCCCCHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHH
FWNIYQTTSPSYILMASIDRCMRIIEEQGDYIFKDYIKRLKNLRENIAKLNNIRLMDSDD
HHHHHHCCCCCEEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCEEEECCCC
ISKIILICDDGKYLYDRLLDEYKVQLEMASFKYVIAMTSVADKQEYYDRFLSALKEIDES
CEEEEEEECCCHHHHHHHHHHHHHEEEHHHEEEEEEEHHHHHHHHHHHHHHHHHHHHHHH
WKVESKDSENDVGESLGYAINNKPEVCMCPADAIDLMDENGYEDLSVNSPDICGRISMSS
CCCCCCCCCHHHHHHHCCCCCCCCCEEECCHHHHHHHCCCCCCCCCCCCCCCCCEEECCE
VLIYPPGMPVVNVGERITGDVCRIIKSAINAGLEVPGLKEGKIRCLR
EEEECCCCCEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECC
>Mature Secondary Structure 
GNIDILEKLEEYSKAGYVPMHMPGGKRNTEYASTSELDITEIDGFDNMHNADGIIKNAS
CCHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCEECCC
DRAAKLYGADKTLMLVNGSTAGILSAICGATKRKGKIIVARNCHVSVYNALIMAQLEPVY
HHHHHHCCCCCEEEEECCCHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHCCCCEE
VIPEVDNDTGIYRGLSLEQIRKCVENNRDAQAVIITSPTYEGVVSEVREIASYLHEKGIP
EEEECCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCC
LIVDEAHGAHFEFSEEFPESAVKAGADIVINSIHKTLPALTQTALLHISGNYVDYDKVER
EEEECCCCCCCCCHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHH
FWNIYQTTSPSYILMASIDRCMRIIEEQGDYIFKDYIKRLKNLRENIAKLNNIRLMDSDD
HHHHHHCCCCCEEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCEEEECCCC
ISKIILICDDGKYLYDRLLDEYKVQLEMASFKYVIAMTSVADKQEYYDRFLSALKEIDES
CEEEEEEECCCHHHHHHHHHHHHHEEEHHHEEEEEEEHHHHHHHHHHHHHHHHHHHHHHH
WKVESKDSENDVGESLGYAINNKPEVCMCPADAIDLMDENGYEDLSVNSPDICGRISMSS
CCCCCCCCCHHHHHHHCCCCCCCCCEEECCHHHHHHHCCCCCCCCCCCCCCCCCEEECCE
VLIYPPGMPVVNVGERITGDVCRIIKSAINAGLEVPGLKEGKIRCLR
EEEECCCCCEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]