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The map label for this gene is glmU [H]

Identifier: 238897235

GI number: 238897235

Start: 5236228

End: 5237598

Strand: Reverse

Name: glmU [H]

Synonym: KP1_5508

Alternate gene names: 238897235

Gene position: 5237598-5236228 (Counterclockwise)

Preceding gene: 238897238

Following gene: 238897234

Centisome position: 99.79

GC content: 58.94

Gene sequence:

>1371_bases
ATGTCAAATAGTGCGATGAGCGTGGTTATCCTTGCTGCAGGCAAAGGGACCCGCATGTATTCCGATCTTCCTAAGGTGCT
GCATACCCTGGCCGGGAAGCCAATGGTGCAGCATGTCATTGATGCCGCTAACGATTTAGGCGCATGTGCGGTACACCTGG
TATACGGCCACGGCGGCGATCTGCTGCGTCAGACTCTGCATGAAGACAACCTGAACTGGGTGCTGCAGGCCGAGCAGCTC
GGAACCGGGCACGCTATGCAGCAGGCGGCGCCATTCTTCAATGATGATGAAGACATCCTGATGCTCTATGGCGACGTGCC
GCTGATCTCCGTTGAGACGCTACAGCGCCTGCGCGCCGCGAAACCACAGGGTGGGATTGGTCTGTTAACGGTGAAGCTGG
ATGACCCAACCGGCTATGGCCGCATTACCCGTGAAAATGGCCAGGTGACGGGCATCGTTGAGCACAAAGATGCCAGCGAG
GCCCAGCGCCAGATCCAGGAAATCAACACCGGGATCCTGATCGCCGGCGGAGCGGATCTAAAGCGCTGGCTGGCGAAACT
CACCAATAACAACGCTCAGGGCGAATACTACATCACCGATATCATCGCCATGGCGCACCAGGAAGGACACCAGATCGTCG
CAGTGCATCCGCAGCGCCTGAGCGAAGTCGAAGGCGTCAACAACCGCCTGCAGCTTGCGCGCCTGGAGCGCGTCTACCAG
GCGGAGCAGGCGGAAAAGCTGCTGCTGGCGGGCGTGATGCTGCGCGATCCGGCGCGTTTCGATCTGCGCGGTACGCTGCA
GCACGGGCGCGATGTAGAGATCGATACTAACGTTATTCTGGAAGGCAACGTGGTGCTGGGCGATCGAGTGAAAATCGGCG
CCGGCTGCGTGATCAAAAACAGCACCATCGGCGATGACTGCGAAATTAGCCCCTACAGCGTGGTGGAAGATGCCCAGCTG
CAGGCGGCCTGCACCATCGGTCCATTTGCCCGTCTGCGCCCGGGCGCCGAACTGCTGGCAGGCGCCCACGTTGGTAACTT
CGTGGAAATGAAAAAAGCGCGTCTCGGGAAAGGCTCCAAGGCGGGTCATCTGACCTATCTGGGCGATGCGGAGATTGGCG
ATAACGTCAATATCGGCGCGGGCACCATCACCTGCAACTACGATGGTGCGAACAAGCATAAAACGATTATTGGCGATGAT
GTCTTTGTCGGCTCGGATACCCAGCTGGTGGCCCCGGTCACGGTAGGCAACGGTGTCACTATCGCCGCCGGCACCACCGT
CACACGCAATATCGCCGATAATGAACTGGTGTTGAGCCGCGTACCGCAGGTCCACAAACAGGGCTGGCAGCGTCCGGTGA
AGAAGAAATAA

Upstream 100 bases:

>100_bases
CCTGGACGTTTTCTCCACGTCTCGTTTTATGATGAAAAATATGTAGAAATTTCAACGTGAAAGGCTTTTACTTTTCGTTC
TAACTACCGTCAGGATGAGT

Downstream 100 bases:

>100_bases
TTTGGATTATCGCCGGGGAAATTTTCCCGGCGAACCAGGATGAGAGGGTCAACATAGATCCCCGTCCGCAGGCAGTACTA
TAACAATAACCCCACTCTCT

Product: bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase

Products: NA

Alternate protein names: UDP-N-acetylglucosamine pyrophosphorylase; N-acetylglucosamine-1-phosphate uridyltransferase; Glucosamine-1-phosphate N-acetyltransferase [H]

Number of amino acids: Translated: 456; Mature: 455

Protein sequence:

>456_residues
MSNSAMSVVILAAGKGTRMYSDLPKVLHTLAGKPMVQHVIDAANDLGACAVHLVYGHGGDLLRQTLHEDNLNWVLQAEQL
GTGHAMQQAAPFFNDDEDILMLYGDVPLISVETLQRLRAAKPQGGIGLLTVKLDDPTGYGRITRENGQVTGIVEHKDASE
AQRQIQEINTGILIAGGADLKRWLAKLTNNNAQGEYYITDIIAMAHQEGHQIVAVHPQRLSEVEGVNNRLQLARLERVYQ
AEQAEKLLLAGVMLRDPARFDLRGTLQHGRDVEIDTNVILEGNVVLGDRVKIGAGCVIKNSTIGDDCEISPYSVVEDAQL
QAACTIGPFARLRPGAELLAGAHVGNFVEMKKARLGKGSKAGHLTYLGDAEIGDNVNIGAGTITCNYDGANKHKTIIGDD
VFVGSDTQLVAPVTVGNGVTIAAGTTVTRNIADNELVLSRVPQVHKQGWQRPVKKK

Sequences:

>Translated_456_residues
MSNSAMSVVILAAGKGTRMYSDLPKVLHTLAGKPMVQHVIDAANDLGACAVHLVYGHGGDLLRQTLHEDNLNWVLQAEQL
GTGHAMQQAAPFFNDDEDILMLYGDVPLISVETLQRLRAAKPQGGIGLLTVKLDDPTGYGRITRENGQVTGIVEHKDASE
AQRQIQEINTGILIAGGADLKRWLAKLTNNNAQGEYYITDIIAMAHQEGHQIVAVHPQRLSEVEGVNNRLQLARLERVYQ
AEQAEKLLLAGVMLRDPARFDLRGTLQHGRDVEIDTNVILEGNVVLGDRVKIGAGCVIKNSTIGDDCEISPYSVVEDAQL
QAACTIGPFARLRPGAELLAGAHVGNFVEMKKARLGKGSKAGHLTYLGDAEIGDNVNIGAGTITCNYDGANKHKTIIGDD
VFVGSDTQLVAPVTVGNGVTIAAGTTVTRNIADNELVLSRVPQVHKQGWQRPVKKK
>Mature_455_residues
SNSAMSVVILAAGKGTRMYSDLPKVLHTLAGKPMVQHVIDAANDLGACAVHLVYGHGGDLLRQTLHEDNLNWVLQAEQLG
TGHAMQQAAPFFNDDEDILMLYGDVPLISVETLQRLRAAKPQGGIGLLTVKLDDPTGYGRITRENGQVTGIVEHKDASEA
QRQIQEINTGILIAGGADLKRWLAKLTNNNAQGEYYITDIIAMAHQEGHQIVAVHPQRLSEVEGVNNRLQLARLERVYQA
EQAEKLLLAGVMLRDPARFDLRGTLQHGRDVEIDTNVILEGNVVLGDRVKIGAGCVIKNSTIGDDCEISPYSVVEDAQLQ
AACTIGPFARLRPGAELLAGAHVGNFVEMKKARLGKGSKAGHLTYLGDAEIGDNVNIGAGTITCNYDGANKHKTIIGDDV
FVGSDTQLVAPVTVGNGVTIAAGTTVTRNIADNELVLSRVPQVHKQGWQRPVKKK

Specific function: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-GlcNAc. Responsible for the acetylation of Glc-N-1-P to give GlcNAc-1-P and for the uridyl transfer from UTP to GlcNAc-1-P which produces UDP-GlcNAc [H]

COG id: COG1207

COG function: function code M; N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Escherichia coli, GI1790168, Length=456, Percent_Identity=89.6929824561403, Blast_Score=841, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005882
- InterPro:   IPR018357
- InterPro:   IPR005835
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.23; =2.3.1.157 [H]

Molecular weight: Translated: 49059; Mature: 48927

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNSAMSVVILAAGKGTRMYSDLPKVLHTLAGKPMVQHVIDAANDLGACAVHLVYGHGGD
CCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEEEECCCHH
LLRQTLHEDNLNWVLQAEQLGTGHAMQQAAPFFNDDEDILMLYGDVPLISVETLQRLRAA
HHHHHHHCCCCEEEEEECCCCCCHHHHHCCCCCCCCCCEEEEECCCCEEEHHHHHHHHHC
KPQGGIGLLTVKLDDPTGYGRITRENGQVTGIVEHKDASEAQRQIQEINTGILIAGGADL
CCCCCEEEEEEEECCCCCCCEEEECCCCEEEEEECCCHHHHHHHHHHCCCCEEEECCHHH
KRWLAKLTNNNAQGEYYITDIIAMAHQEGHQIVAVHPQRLSEVEGVNNRLQLARLERVYQ
HHHHHHHHCCCCCCCEEHHHHHHHHHCCCCEEEEECHHHHHHHHCCCHHHHHHHHHHHHH
AEQAEKLLLAGVMLRDPARFDLRGTLQHGRDVEIDTNVILEGNVVLGDRVKIGAGCVIKN
HHHHHHHHHHHHHHCCCCCCCEEEHHCCCCCEEECCEEEEECCEEECCCEEECCCEEEEC
STIGDDCEISPYSVVEDAQLQAACTIGPFARLRPGAELLAGAHVGNFVEMKKARLGKGSK
CCCCCCCCCCCCCCCCCCCEEEEEEECCHHHCCCCHHHHHHCCCCCHHHHHHHHCCCCCC
AGHLTYLGDAEIGDNVNIGAGTITCNYDGANKHKTIIGDDVFVGSDTQLVAPVTVGNGVT
CCEEEEECCCCCCCCCCCCCEEEEEECCCCCCCCEEECCCEEECCCCEEEEEEEECCCEE
IAAGTTVTRNIADNELVLSRVPQVHKQGWQRPVKKK
EEECCEEEECCCCCHHHHHHCCHHHHHHHCCCCCCC
>Mature Secondary Structure 
SNSAMSVVILAAGKGTRMYSDLPKVLHTLAGKPMVQHVIDAANDLGACAVHLVYGHGGD
CCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEEEECCCHH
LLRQTLHEDNLNWVLQAEQLGTGHAMQQAAPFFNDDEDILMLYGDVPLISVETLQRLRAA
HHHHHHHCCCCEEEEEECCCCCCHHHHHCCCCCCCCCCEEEEECCCCEEEHHHHHHHHHC
KPQGGIGLLTVKLDDPTGYGRITRENGQVTGIVEHKDASEAQRQIQEINTGILIAGGADL
CCCCCEEEEEEEECCCCCCCEEEECCCCEEEEEECCCHHHHHHHHHHCCCCEEEECCHHH
KRWLAKLTNNNAQGEYYITDIIAMAHQEGHQIVAVHPQRLSEVEGVNNRLQLARLERVYQ
HHHHHHHHCCCCCCCEEHHHHHHHHHCCCCEEEEECHHHHHHHHCCCHHHHHHHHHHHHH
AEQAEKLLLAGVMLRDPARFDLRGTLQHGRDVEIDTNVILEGNVVLGDRVKIGAGCVIKN
HHHHHHHHHHHHHHCCCCCCCEEEHHCCCCCEEECCEEEEECCEEECCCEEECCCEEEEC
STIGDDCEISPYSVVEDAQLQAACTIGPFARLRPGAELLAGAHVGNFVEMKKARLGKGSK
CCCCCCCCCCCCCCCCCCCEEEEEEECCHHHCCCCHHHHHHCCCCCHHHHHHHHCCCCCC
AGHLTYLGDAEIGDNVNIGAGTITCNYDGANKHKTIIGDDVFVGSDTQLVAPVTVGNGVT
CCEEEEECCCCCCCCCCCCCEEEEEECCCCCCCCEEECCCEEECCCCEEEEEEEECCCEE
IAAGTTVTRNIADNELVLSRVPQVHKQGWQRPVKKK
EEECCEEEECCCCCHHHHHHCCHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA