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The map label for this gene is yidY [H]

Identifier: 238897219

GI number: 238897219

Start: 5219278

End: 5220456

Strand: Direct

Name: yidY [H]

Synonym: KP1_5490

Alternate gene names: 238897219

Gene position: 5219278-5220456 (Clockwise)

Preceding gene: 238897218

Following gene: 238897220

Centisome position: 99.44

GC content: 60.47

Gene sequence:

>1179_bases
ATGACACGCTTTCTTCTCTGCAGCTTTGCCCTGGTTCTGCTCTACCCCTCCGGCATCGATATGTATCTGGTCGGCCTGCC
GCGTATTGCTCAGGACCTGGGGGCCAGCGAGGCGCAATTACATATCGCCTTCTCGGTCTATCTGGCCGGTATGGCCTCCG
CGATGCTGTTTGCTGGCCGCATCGCCGACCGCTCGGGGCGTAAGCCTGTCGCTATTGTAGGTGCAGCGATCTTTGTTATC
GCCTCCCTGCTCTGCGCCCAGGCGCATACCAGCAGCCACTTCCTCATCGGACGCTTTATCCAGGGGATCGGCGCCGGCAG
CTGCTACGTGGTGGCTTTCGCTATCCTGCGCGATACGCTGGACGACCGTCGCCGCGCCAAGGTGCTGTCGTTGCTCAACG
GCATCACCTGCATTATCCCCGTCCTGGCGCCGGTGCTTGGCCACCTGATTATGCTGAAATATCCGTGGCAGAGCCTGTTC
TACACGATGACCGGCATGGGCGTCATGGTCGCTGTGCTGTCGGTCTTTATCCTGCGTGAAACGCGGCCGACGGCGCCTCC
GCAGGCAGCGTCACCGCAGCATGACGCTGGCGAATCGCTGTTGAACCGCTTTTTCCTCAGCCGCTTACTCATTACCACCC
TCAGCGTGACGGTGATCCTGACCTACGTTAACGTCTCGCCGGTACTAATGATGGAAGAGATGGGGTTCGACCGGGGAACT
TACTCAATGGCGATGGCTCTGATGGCGATGATCAGCATGGCGGTCTCCTTCTCAACGCCGTTCGTCCTGTCGCTGTTTAA
CCCCCGCACCTTAATGCTGACCTCACAGGTGCTGTTTCTGGCGGCAGGCGTGACGCTGAGCCTCGCCACTCGCCAGGCCG
TCACCCTGATCGGGCTGGGCATGATTTGCGCCGGCTTCTCCGTTGGGTTCGGTGTCGCGATGAGCCAGGCGCTGGGGCCG
TTCACGCTGCGCGCGGGCGTCGCCAGCTCGGTCCTCGGCATCGCGCAGGTGTGCGGTTCATCGCTGTGGATTTGGCTCGC
CGCCATCATCGGACTCAGCGCAATGAATATGCTGATCGGGATACTCATTGCCTGTAGCATAGTGAGCCTTGTTTTGTTAC
TGGTCGTTACCCCGCCGCGGGTTGCGCAATACGATGAAGAAGCCGCTGTCGAGTCTTGA

Upstream 100 bases:

>100_bases
GCTCGCATTTCCTGCCAGGAAAAGAGCGTTGTCCAAATGGCAACTCGTCTTACGGCGCGTTCCTCACTATGCTGAACGCC
ATTCACATCGCGAGGATCCC

Downstream 100 bases:

>100_bases
TCTTAATTTACTCCTCTGCCTGCAGCTCCTGACCCAGGAGCTCAGCGTTACCCGTACGGCGAAGCGGATGAACGTTTCGC
CGTCAGCGGTGAGCAAGTCG

Product: multidrug efflux system protein MdtL

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 392; Mature: 391

Protein sequence:

>392_residues
MTRFLLCSFALVLLYPSGIDMYLVGLPRIAQDLGASEAQLHIAFSVYLAGMASAMLFAGRIADRSGRKPVAIVGAAIFVI
ASLLCAQAHTSSHFLIGRFIQGIGAGSCYVVAFAILRDTLDDRRRAKVLSLLNGITCIIPVLAPVLGHLIMLKYPWQSLF
YTMTGMGVMVAVLSVFILRETRPTAPPQAASPQHDAGESLLNRFFLSRLLITTLSVTVILTYVNVSPVLMMEEMGFDRGT
YSMAMALMAMISMAVSFSTPFVLSLFNPRTLMLTSQVLFLAAGVTLSLATRQAVTLIGLGMICAGFSVGFGVAMSQALGP
FTLRAGVASSVLGIAQVCGSSLWIWLAAIIGLSAMNMLIGILIACSIVSLVLLLVVTPPRVAQYDEEAAVES

Sequences:

>Translated_392_residues
MTRFLLCSFALVLLYPSGIDMYLVGLPRIAQDLGASEAQLHIAFSVYLAGMASAMLFAGRIADRSGRKPVAIVGAAIFVI
ASLLCAQAHTSSHFLIGRFIQGIGAGSCYVVAFAILRDTLDDRRRAKVLSLLNGITCIIPVLAPVLGHLIMLKYPWQSLF
YTMTGMGVMVAVLSVFILRETRPTAPPQAASPQHDAGESLLNRFFLSRLLITTLSVTVILTYVNVSPVLMMEEMGFDRGT
YSMAMALMAMISMAVSFSTPFVLSLFNPRTLMLTSQVLFLAAGVTLSLATRQAVTLIGLGMICAGFSVGFGVAMSQALGP
FTLRAGVASSVLGIAQVCGSSLWIWLAAIIGLSAMNMLIGILIACSIVSLVLLLVVTPPRVAQYDEEAAVES
>Mature_391_residues
TRFLLCSFALVLLYPSGIDMYLVGLPRIAQDLGASEAQLHIAFSVYLAGMASAMLFAGRIADRSGRKPVAIVGAAIFVIA
SLLCAQAHTSSHFLIGRFIQGIGAGSCYVVAFAILRDTLDDRRRAKVLSLLNGITCIIPVLAPVLGHLIMLKYPWQSLFY
TMTGMGVMVAVLSVFILRETRPTAPPQAASPQHDAGESLLNRFFLSRLLITTLSVTVILTYVNVSPVLMMEEMGFDRGTY
SMAMALMAMISMAVSFSTPFVLSLFNPRTLMLTSQVLFLAAGVTLSLATRQAVTLIGLGMICAGFSVGFGVAMSQALGPF
TLRAGVASSVLGIAQVCGSSLWIWLAAIIGLSAMNMLIGILIACSIVSLVLLLVVTPPRVAQYDEEAAVES

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. DHA1 family. MdtL (TC 2.A.1.2.22) subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790146, Length=387, Percent_Identity=75.4521963824289, Blast_Score=590, Evalue=1e-170,
Organism=Escherichia coli, GI1788509, Length=398, Percent_Identity=24.6231155778894, Blast_Score=101, Evalue=7e-23,
Organism=Escherichia coli, GI48994889, Length=238, Percent_Identity=27.7310924369748, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1790794, Length=215, Percent_Identity=28.8372093023256, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI87082312, Length=330, Percent_Identity=27.5757575757576, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787065, Length=169, Percent_Identity=26.0355029585799, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 41759; Mature: 41627

Theoretical pI: Translated: 8.66; Mature: 8.66

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHCCCCHHHHCCHHHCCCC
>Mature Secondary Structure 
TRFLLCSFALVLLYPSGIDMYLVGLPRIAQDLGASEAQLHIAFSVYLAGMASAMLFAGR
CHHHHHHHHHHHHCCCCCCEEEECHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
IADRSGRKPVAIVGAAIFVIASLLCAQAHTSSHFLIGRFIQGIGAGSCYVVAFAILRDTL
HHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHH
DDRRRAKVLSLLNGITCIIPVLAPVLGHLIMLKYPWQSLFYTMTGMGVMVAVLSVFILRE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHC
TRPTAPPQAASPQHDAGESLLNRFFLSRLLITTLSVTVILTYVNVSPVLMMEEMGFDRGT
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCH
YSMAMALMAMISMAVSFSTPFVLSLFNPRTLMLTSQVLFLAAGVTLSLATRQAVTLIGLG
HHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
MICAGFSVGFGVAMSQALGPFTLRAGVASSVLGIAQVCGSSLWIWLAAIIGLSAMNMLIG
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
ILIACSIVSLVLLLVVTPPRVAQYDEEAAVES
HHHHHHHHHHHHHHHCCCCHHHHCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA