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The map label for this gene is dgoR [H]

Identifier: 238897205

GI number: 238897205

Start: 5203618

End: 5204307

Strand: Reverse

Name: dgoR [H]

Synonym: KP1_5476

Alternate gene names: 238897205

Gene position: 5204307-5203618 (Counterclockwise)

Preceding gene: 238897206

Following gene: 238897204

Centisome position: 99.16

GC content: 56.23

Gene sequence:

>690_bases
ATGACTCTCAATAAGACCGATCGCATTGTGATCTCGCTGGGCAAACAGATCGTCAGCGGTAAATACGTCCCGGGTTCGGC
GCTTCCGGCCGAAGCGGAACTCTGTGAGGAGTTTGAAACCTCGCGCAACATCATTCGTGAAGTGTTTCGTTCCCTGATGG
CGAAGCGGCTGATTGAAATGAAGCGCTATCGCGGCGCGTTTGTCGCTCCCAGAAACCAGTGGAACTACCTCGACACCGAG
GTGCTGCAGTGGGTACTGGAAAATGACTATGACCCGCGTCTTATCAGCGCGATGAGTGAAGTGCGCAACCTGGTTGAACC
CGCCATCGCGCGTTGGGCGGCGGAACGCGCCACCTCAAGCGATCTGGCGGAAATCGAGTCGGCGCTCAATGACATGATCG
CCAACAACCAAAACCGGGATGCCTTTAACGAAGCGGATATTCGCTACCACGAGGCGGTGCTGCAGTCAGCACATAACCCG
GTTTTGCAGCAGCTTAGCGTGGCGATCAGTTCGCTGCAGCGGGCGGTATTTGAACGGACCTGGATGGGCGATGAAGGCAA
CATGCCGAAAACCCTCCAGGAACATAAAGCGCTATTTGACGCCATTCGGCATCAGGATAGCGACGCGGCGGAGCAGGCGG
CGTTGACGATGATCGCCAGCTCGACACGAAGGCTTAAGGAAATCACATGA

Upstream 100 bases:

>100_bases
TGTTGATAACGTACAGCATCACGTTAGTAGTACAAACATGAGGCGAAATTCAGCAGCGACGGTAAAGTAGAGCAGTACAC
ATAGAGCACAAGGACTCTCC

Downstream 100 bases:

>100_bases
CGGCTCGCTACATCGCAATAGATTGGGGATCGACGAATTTACGCGCCTGGCTTTATCAGGGCGAAGAATGCCTGGAAAGC
AGGCAATCTGAAGCAGGCGT

Product: GntR family transcriptional repressor for galactonate utilization

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 228

Protein sequence:

>229_residues
MTLNKTDRIVISLGKQIVSGKYVPGSALPAEAELCEEFETSRNIIREVFRSLMAKRLIEMKRYRGAFVAPRNQWNYLDTE
VLQWVLENDYDPRLISAMSEVRNLVEPAIARWAAERATSSDLAEIESALNDMIANNQNRDAFNEADIRYHEAVLQSAHNP
VLQQLSVAISSLQRAVFERTWMGDEGNMPKTLQEHKALFDAIRHQDSDAAEQAALTMIASSTRRLKEIT

Sequences:

>Translated_229_residues
MTLNKTDRIVISLGKQIVSGKYVPGSALPAEAELCEEFETSRNIIREVFRSLMAKRLIEMKRYRGAFVAPRNQWNYLDTE
VLQWVLENDYDPRLISAMSEVRNLVEPAIARWAAERATSSDLAEIESALNDMIANNQNRDAFNEADIRYHEAVLQSAHNP
VLQQLSVAISSLQRAVFERTWMGDEGNMPKTLQEHKALFDAIRHQDSDAAEQAALTMIASSTRRLKEIT
>Mature_228_residues
TLNKTDRIVISLGKQIVSGKYVPGSALPAEAELCEEFETSRNIIREVFRSLMAKRLIEMKRYRGAFVAPRNQWNYLDTEV
LQWVLENDYDPRLISAMSEVRNLVEPAIARWAAERATSSDLAEIESALNDMIANNQNRDAFNEADIRYHEAVLQSAHNPV
LQQLSVAISSLQRAVFERTWMGDEGNMPKTLQEHKALFDAIRHQDSDAAEQAALTMIASSTRRLKEIT

Specific function: Repressor for the dgoRKAT operon. Binds D-galactonate as an inducer [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI48994955, Length=229, Percent_Identity=93.8864628820961, Blast_Score=447, Evalue=1e-127,
Organism=Escherichia coli, GI48994961, Length=213, Percent_Identity=30.0469483568075, Blast_Score=107, Evalue=9e-25,
Organism=Escherichia coli, GI1789353, Length=228, Percent_Identity=25.8771929824561, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1790032, Length=216, Percent_Identity=27.3148148148148, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1790780, Length=229, Percent_Identity=25.3275109170306, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI1786303, Length=154, Percent_Identity=32.4675324675325, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI1789621, Length=196, Percent_Identity=26.530612244898, Blast_Score=61, Evalue=5e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 26008; Mature: 25877

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLNKTDRIVISLGKQIVSGKYVPGSALPAEAELCEEFETSRNIIREVFRSLMAKRLIEM
CCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KRYRGAFVAPRNQWNYLDTEVLQWVLENDYDPRLISAMSEVRNLVEPAIARWAAERATSS
HHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
DLAEIESALNDMIANNQNRDAFNEADIRYHEAVLQSAHNPVLQQLSVAISSLQRAVFERT
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHH
WMGDEGNMPKTLQEHKALFDAIRHQDSDAAEQAALTMIASSTRRLKEIT
HCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TLNKTDRIVISLGKQIVSGKYVPGSALPAEAELCEEFETSRNIIREVFRSLMAKRLIEM
CCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KRYRGAFVAPRNQWNYLDTEVLQWVLENDYDPRLISAMSEVRNLVEPAIARWAAERATSS
HHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
DLAEIESALNDMIANNQNRDAFNEADIRYHEAVLQSAHNPVLQQLSVAISSLQRAVFERT
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHH
WMGDEGNMPKTLQEHKALFDAIRHQDSDAAEQAALTMIASSTRRLKEIT
HCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503 [H]