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The map label for this gene is dgoD [H]

Identifier: 238897202

GI number: 238897202

Start: 5200997

End: 5202145

Strand: Reverse

Name: dgoD [H]

Synonym: KP1_5473

Alternate gene names: 238897202

Gene position: 5202145-5200997 (Counterclockwise)

Preceding gene: 238897203

Following gene: 238897201

Centisome position: 99.12

GC content: 53.79

Gene sequence:

>1149_bases
ATGAAAATAACCAATATCACCACGTACCGTTTACCTCCGCGTTGGATGTTCCTGAAGATTGAAACCGATGAAGGCATCGT
CGGCTGGGGCGAACCGGTGATTGAAGGGCGCGCCCGTACGGTGGAGGCAGCCGTTCATGAATTTGGCGATTACCTGATTG
GTCAGGATCCGGCGCGGATTAATGACCTGTGGCAGGTAATGTACCGCGGCGGCTTTTATCGCGGCGGCCCGATTATGATG
AGCGCCATCGCCGGTATTGATCAGGCGCTATGGGATATTAAAGGTAAGGTCCTGAATGCCCCGGTGTGGCAACTGATGGG
CGGGCTGGTGCGCGACAAAATTAAAGCCTACAGCTGGGTGGGCGGCGACCGCCCCGCCGAAGTGATTGACGGGATTAAGA
AGCTGCGCGGCATTGGTTTTGACACCTTTAAATTAAACGGCTGCGAAGAGATGGGTATCATTGATAATTCCCGCGCGGTT
GACGCGGCGGTGAATACCGTGGCGCAAATCCGCGAAGCGTTTGGCAATGAAATTGAGTTTGGTCTCGATTTTCATGGCCG
CGTTAGCGCGCCGATGGCTAAGGTATTAATTAAAGAGCTGGAGCCATATCGCCCATTATTTATTGAGGAACCGGTATTAG
CCGAGCAGGCGGAATATTATCCGCGGCTGGCGGCGCAAACCCATATTCCCATTGCCGCCGGCGAACGTATGTTTTCGCGC
TTTGAATTTAAACGGGTACTGGAAGCGGGCGGGGTGGCTATTTTACAGCCCGATCTGTCGCACGCAGGCGGTATTACCGA
ATGCTATAAAATTGCCGGAATGGCGGAAGCCTATGACGTTGGGCTGGCGCCGCACTGCCCGCTGGGGCCGATCGCGCTGG
CAGCCTGTCTGCACGTCGATTTCGTTTCGCATAACGCGGTCTTCCAGGAGCAGAGCATGGGGATCCATTACAACAAAGGC
GCCGAACTGCTTGATTTTGTGAAAAATAAAGAAGATTTCAATATGGAAGGCGGCTTCTTTAAACCATTGATGAAGCCGGG
GCTGGGCGTGGAAATTGATGAGGCCCGCGTGATTGAGTTAAGTAAAAACGCGCCGGACTGGCGAAATCCGTTGTGGCGGT
ATGAGGATGGATCTGTCGCCGAATGGTAA

Upstream 100 bases:

>100_bases
GGGCAGGATTGGGTAGCGATCTCTATCGTGCCGGCCAGCCGGTTGAACGTACCGCGCAGCAGGCAGCCGCATTCGTAAAA
GCGTATCGAGAGGCAGTGAA

Downstream 100 bases:

>100_bases
ATGCGCGTCATACTTCGCACTGGTGATGCGTTGGCTGCATTTTCTTACCCTGGTCACATACTATTGTATGCTCCCAGGGA
TGCGAAAATTTGCCGCCTTT

Product: galactonate dehydratase

Products: NA

Alternate protein names: GalD 1 [H]

Number of amino acids: Translated: 382; Mature: 382

Protein sequence:

>382_residues
MKITNITTYRLPPRWMFLKIETDEGIVGWGEPVIEGRARTVEAAVHEFGDYLIGQDPARINDLWQVMYRGGFYRGGPIMM
SAIAGIDQALWDIKGKVLNAPVWQLMGGLVRDKIKAYSWVGGDRPAEVIDGIKKLRGIGFDTFKLNGCEEMGIIDNSRAV
DAAVNTVAQIREAFGNEIEFGLDFHGRVSAPMAKVLIKELEPYRPLFIEEPVLAEQAEYYPRLAAQTHIPIAAGERMFSR
FEFKRVLEAGGVAILQPDLSHAGGITECYKIAGMAEAYDVGLAPHCPLGPIALAACLHVDFVSHNAVFQEQSMGIHYNKG
AELLDFVKNKEDFNMEGGFFKPLMKPGLGVEIDEARVIELSKNAPDWRNPLWRYEDGSVAEW

Sequences:

>Translated_382_residues
MKITNITTYRLPPRWMFLKIETDEGIVGWGEPVIEGRARTVEAAVHEFGDYLIGQDPARINDLWQVMYRGGFYRGGPIMM
SAIAGIDQALWDIKGKVLNAPVWQLMGGLVRDKIKAYSWVGGDRPAEVIDGIKKLRGIGFDTFKLNGCEEMGIIDNSRAV
DAAVNTVAQIREAFGNEIEFGLDFHGRVSAPMAKVLIKELEPYRPLFIEEPVLAEQAEYYPRLAAQTHIPIAAGERMFSR
FEFKRVLEAGGVAILQPDLSHAGGITECYKIAGMAEAYDVGLAPHCPLGPIALAACLHVDFVSHNAVFQEQSMGIHYNKG
AELLDFVKNKEDFNMEGGFFKPLMKPGLGVEIDEARVIELSKNAPDWRNPLWRYEDGSVAEW
>Mature_382_residues
MKITNITTYRLPPRWMFLKIETDEGIVGWGEPVIEGRARTVEAAVHEFGDYLIGQDPARINDLWQVMYRGGFYRGGPIMM
SAIAGIDQALWDIKGKVLNAPVWQLMGGLVRDKIKAYSWVGGDRPAEVIDGIKKLRGIGFDTFKLNGCEEMGIIDNSRAV
DAAVNTVAQIREAFGNEIEFGLDFHGRVSAPMAKVLIKELEPYRPLFIEEPVLAEQAEYYPRLAAQTHIPIAAGERMFSR
FEFKRVLEAGGVAILQPDLSHAGGITECYKIAGMAEAYDVGLAPHCPLGPIALAACLHVDFVSHNAVFQEQSMGIHYNKG
AELLDFVKNKEDFNMEGGFFKPLMKPGLGVEIDEARVIELSKNAPDWRNPLWRYEDGSVAEW

Specific function: Catalyzes the dehydration of D-galactonate to 2-keto-3- deoxy-D-galactonate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily [H]

Homologues:

Organism=Escherichia coli, GI48994953, Length=382, Percent_Identity=92.6701570680628, Blast_Score=742, Evalue=0.0,
Organism=Escherichia coli, GI1787864, Length=413, Percent_Identity=30.0242130750605, Blast_Score=183, Evalue=1e-47,
Organism=Escherichia coli, GI226510960, Length=344, Percent_Identity=28.1976744186047, Blast_Score=88, Evalue=8e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018110
- InterPro:   IPR013342
- InterPro:   IPR013341
- InterPro:   IPR001354 [H]

Pfam domain/function: PF01188 MR_MLE; PF02746 MR_MLE_N [H]

EC number: =4.2.1.6 [H]

Molecular weight: Translated: 42545; Mature: 42545

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: PS00908 MR_MLE_1 ; PS00909 MR_MLE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKITNITTYRLPPRWMFLKIETDEGIVGWGEPVIEGRARTVEAAVHEFGDYLIGQDPARI
CCCCCEEEEECCCCEEEEEEECCCCCEECCCHHHCCCHHHHHHHHHHHHHHHCCCCCHHH
NDLWQVMYRGGFYRGGPIMMSAIAGIDQALWDIKGKVLNAPVWQLMGGLVRDKIKAYSWV
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCHHCCCCHHHHHHHHHHHHHHHHHCC
GGDRPAEVIDGIKKLRGIGFDTFKLNGCEEMGIIDNSRAVDAAVNTVAQIREAFGNEIEF
CCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEE
GLDFHGRVSAPMAKVLIKELEPYRPLFIEEPVLAEQAEYYPRLAAQTHIPIAAGERMFSR
CCCCCCCCCHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
FEFKRVLEAGGVAILQPDLSHAGGITECYKIAGMAEAYDVGLAPHCPLGPIALAACLHVD
HHHHHHHHHCCEEEECCCCCCCCCHHHHHHHHCCHHHHHCCCCCCCCCHHHHHHHHHHHH
FVSHNAVFQEQSMGIHYNKGAELLDFVKNKEDFNMEGGFFKPLMKPGLGVEIDEARVIEL
HHHCCHHHHHHCCCEEECCCHHHHHHHHCCCCCCCCCCCHHHHHCCCCCEEECCCEEEEE
SKNAPDWRNPLWRYEDGSVAEW
CCCCCHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MKITNITTYRLPPRWMFLKIETDEGIVGWGEPVIEGRARTVEAAVHEFGDYLIGQDPARI
CCCCCEEEEECCCCEEEEEEECCCCCEECCCHHHCCCHHHHHHHHHHHHHHHCCCCCHHH
NDLWQVMYRGGFYRGGPIMMSAIAGIDQALWDIKGKVLNAPVWQLMGGLVRDKIKAYSWV
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCHHCCCCHHHHHHHHHHHHHHHHHCC
GGDRPAEVIDGIKKLRGIGFDTFKLNGCEEMGIIDNSRAVDAAVNTVAQIREAFGNEIEF
CCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEE
GLDFHGRVSAPMAKVLIKELEPYRPLFIEEPVLAEQAEYYPRLAAQTHIPIAAGERMFSR
CCCCCCCCCHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
FEFKRVLEAGGVAILQPDLSHAGGITECYKIAGMAEAYDVGLAPHCPLGPIALAACLHVD
HHHHHHHHHCCEEEECCCCCCCCCHHHHHHHHCCHHHHHCCCCCCCCCHHHHHHHHHHHH
FVSHNAVFQEQSMGIHYNKGAELLDFVKNKEDFNMEGGFFKPLMKPGLGVEIDEARVIEL
HHHCCHHHHHHCCCEEECCCHHHHHHHHCCCCCCCCCCCHHHHHCCCCCEEECCCEEEEE
SKNAPDWRNPLWRYEDGSVAEW
CCCCCHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA