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The map label for this gene is dsdC [H]

Identifier: 238897186

GI number: 238897186

Start: 5184786

End: 5185709

Strand: Reverse

Name: dsdC [H]

Synonym: KP1_5456

Alternate gene names: 238897186

Gene position: 5185709-5184786 (Counterclockwise)

Preceding gene: 238897189

Following gene: 238897181

Centisome position: 98.8

GC content: 58.77

Gene sequence:

>924_bases
ATGGATGTGCTAAAAACCTTAGGTACCCGGTTGCTGAACGGCTGGCAACTCTCCAGGCTGTCGACGTTTGAGGTGGCGGC
GCGGCACGAGTCGTTCGCCCTTGCCGCCGACGAGCTGGCGCTCACCCCAAGCGCCGTCAGTCACCGGATTAATCAGTTGG
AAGAGGAGCTGGGGATCCAGCTCTTTGTCCGCTCGCACCGCAAAGTGGAGCTGACGCGTGAAGGGAAGCGCGTTTACTGG
GCGCTGAAGGCGTCGCTGGATGGTCTCAATCAGGAGATTCTGGACATCAAAAACCAGGAGCTCTCCGGCAGTCTGACGGT
CTACTCGCGGCCCTCTATCGCCCAGTGCTGGCTGGTGCCGGCGCTGGGGGATTTCAGTCGCCGCTACCCGGCCATCTCGC
TGACCGTGCTGACCGGCAACGATAACGTCAACCTGCAGCGGGCGGGTATCGATCTGGCAATCTATTTTGATGACGCGCCG
TCGTCGCAGCTAAGCCACCATTTTCTGATGGATGAGGCGATCGTGCCGGTATGTACGCCGTATTACGCCCGCCAGCTGCA
GTTAACGTCAAATCCTGCCAGTCTGCGCCACTGTACGCTGCTTCACGATCGCCAGGCATGGAGCAATGATTCCGGCACCG
ATGAATGGTTCAGTTGGGCACAGCAATTTGGGATTGAACTGCCGCAATCGTCGGGCATTGGCTTCGATCGTTCTGATTTA
GCGGTGATTGCGGCGATGAATCATGTCGGGGTAGCGATGGGGCGTAAACGGCTGGTGCAGAAGCGGTTAGAGAGCGGCGA
GCTTATCGCGCCGTTCGGCGATATGACGCTGAAATGCCATCAGCATTATTACGTGACCACCCTGCCGGGCCGCCAGTGGC
CGAAAATCGACGCCTTTATCGAGTGGCTGCATAGCCTGACCTGA

Upstream 100 bases:

>100_bases
CCTCTAAATATGCTATGGGTCAAATTAAATCATCCTTTAGCGGAAGTTCCGGCGTTATTTTTTTATCATCCAGACTCCCT
TTTATCGCCAGGAGCGCATA

Downstream 100 bases:

>100_bases
AAAAGAGCCGGGCTATCCCTCGGAGTTGTTAGGGAGGCCGGGTAAGGCGTGCGCCGCCACCCGGCAAAATGACGGCACTG
CGCTTGCGCGGGCCGGCAGA

Product: DNA-binding transcriptional regulator DsdC

Products: NA

Alternate protein names: D-serine deaminase activator [H]

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MDVLKTLGTRLLNGWQLSRLSTFEVAARHESFALAADELALTPSAVSHRINQLEEELGIQLFVRSHRKVELTREGKRVYW
ALKASLDGLNQEILDIKNQELSGSLTVYSRPSIAQCWLVPALGDFSRRYPAISLTVLTGNDNVNLQRAGIDLAIYFDDAP
SSQLSHHFLMDEAIVPVCTPYYARQLQLTSNPASLRHCTLLHDRQAWSNDSGTDEWFSWAQQFGIELPQSSGIGFDRSDL
AVIAAMNHVGVAMGRKRLVQKRLESGELIAPFGDMTLKCHQHYYVTTLPGRQWPKIDAFIEWLHSLT

Sequences:

>Translated_307_residues
MDVLKTLGTRLLNGWQLSRLSTFEVAARHESFALAADELALTPSAVSHRINQLEEELGIQLFVRSHRKVELTREGKRVYW
ALKASLDGLNQEILDIKNQELSGSLTVYSRPSIAQCWLVPALGDFSRRYPAISLTVLTGNDNVNLQRAGIDLAIYFDDAP
SSQLSHHFLMDEAIVPVCTPYYARQLQLTSNPASLRHCTLLHDRQAWSNDSGTDEWFSWAQQFGIELPQSSGIGFDRSDL
AVIAAMNHVGVAMGRKRLVQKRLESGELIAPFGDMTLKCHQHYYVTTLPGRQWPKIDAFIEWLHSLT
>Mature_307_residues
MDVLKTLGTRLLNGWQLSRLSTFEVAARHESFALAADELALTPSAVSHRINQLEEELGIQLFVRSHRKVELTREGKRVYW
ALKASLDGLNQEILDIKNQELSGSLTVYSRPSIAQCWLVPALGDFSRRYPAISLTVLTGNDNVNLQRAGIDLAIYFDDAP
SSQLSHHFLMDEAIVPVCTPYYARQLQLTSNPASLRHCTLLHDRQAWSNDSGTDEWFSWAQQFGIELPQSSGIGFDRSDL
AVIAAMNHVGVAMGRKRLVQKRLESGELIAPFGDMTLKCHQHYYVTTLPGRQWPKIDAFIEWLHSLT

Specific function: Regulates the expression of the dsd operon for D-serine deaminase (dsdA) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788706, Length=303, Percent_Identity=83.1683168316832, Blast_Score=540, Evalue=1e-155,
Organism=Escherichia coli, GI1786448, Length=297, Percent_Identity=32.6599326599327, Blast_Score=147, Evalue=9e-37,
Organism=Escherichia coli, GI1789173, Length=288, Percent_Identity=31.5972222222222, Blast_Score=144, Evalue=8e-36,
Organism=Escherichia coli, GI1787128, Length=301, Percent_Identity=26.9102990033223, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI145693193, Length=258, Percent_Identity=27.906976744186, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI145693105, Length=179, Percent_Identity=29.0502793296089, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1786401, Length=291, Percent_Identity=23.7113402061856, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788748, Length=169, Percent_Identity=27.810650887574, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1789639, Length=186, Percent_Identity=26.8817204301075, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI157672245, Length=175, Percent_Identity=32, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI87081978, Length=172, Percent_Identity=30.8139534883721, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1790208, Length=126, Percent_Identity=31.7460317460317, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1789440, Length=271, Percent_Identity=26.1992619926199, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1790262, Length=189, Percent_Identity=26.984126984127, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011781
- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34573; Mature: 34573

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVLKTLGTRLLNGWQLSRLSTFEVAARHESFALAADELALTPSAVSHRINQLEEELGIQ
CCHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCEEEHHHHCCCHHHHHHHHHHHHHHHCEE
LFVRSHRKVELTREGKRVYWALKASLDGLNQEILDIKNQELSGSLTVYSRPSIAQCWLVP
EEEECCCEEEEEECCCEEEEEEECCCCCCCHHHHHCCCCCCCCEEEEEECCCCEEEEEEC
ALGDFSRRYPAISLTVLTGNDNVNLQRAGIDLAIYFDDAPSSQLSHHFLMDEAIVPVCTP
CHHHHHHCCCEEEEEEEECCCCCEEEECCEEEEEEECCCCCHHHHHHHHHHHCCCCCCCC
YYARQLQLTSNPASLRHCTLLHDRQAWSNDSGTDEWFSWAQQFGIELPQSSGIGFDRSDL
HHHEEEEECCCCCCHHEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCE
AVIAAMNHVGVAMGRKRLVQKRLESGELIAPFGDMTLKCHQHYYVTTLPGRQWPKIDAFI
EEEEHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCEEEEECEEEEEECCCCCCCCHHHHH
EWLHSLT
HHHHHCC
>Mature Secondary Structure
MDVLKTLGTRLLNGWQLSRLSTFEVAARHESFALAADELALTPSAVSHRINQLEEELGIQ
CCHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCEEEHHHHCCCHHHHHHHHHHHHHHHCEE
LFVRSHRKVELTREGKRVYWALKASLDGLNQEILDIKNQELSGSLTVYSRPSIAQCWLVP
EEEECCCEEEEEECCCEEEEEEECCCCCCCHHHHHCCCCCCCCEEEEEECCCCEEEEEEC
ALGDFSRRYPAISLTVLTGNDNVNLQRAGIDLAIYFDDAPSSQLSHHFLMDEAIVPVCTP
CHHHHHHCCCEEEEEEEECCCCCEEEECCEEEEEEECCCCCHHHHHHHHHHHCCCCCCCC
YYARQLQLTSNPASLRHCTLLHDRQAWSNDSGTDEWFSWAQQFGIELPQSSGIGFDRSDL
HHHEEEEECCCCCCHHEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCE
AVIAAMNHVGVAMGRKRLVQKRLESGELIAPFGDMTLKCHQHYYVTTLPGRQWPKIDAFI
EEEEHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCEEEEECEEEEEECCCCCCCCHHHHH
EWLHSLT
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7592420; 9205837; 9278503 [H]