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The map label for this gene is phnU [H]

Identifier: 238897165

GI number: 238897165

Start: 5165036

End: 5165896

Strand: Reverse

Name: phnU [H]

Synonym: KP1_5430

Alternate gene names: 238897165

Gene position: 5165896-5165036 (Counterclockwise)

Preceding gene: 238897166

Following gene: 238897164

Centisome position: 98.43

GC content: 57.96

Gene sequence:

>861_bases
ATGGCGCAAACCCTCACGCTTGCGCGTCCGGCGCGAAACCTACGCCCTTACCTGTGGCTGGCGTTGCCGCTGCTGGTGCT
GGCGACGCTGTTTTTCTATCCGCTGCTGCTGATCGCCGAACAGGCGCTGCGCGACGCCAGCGGCAACCTGAGCCTCGAGA
CCTTCTGGCAGGTGATTGACTCAAAACGCTTTATTGGCGCGTTGCTCAATACCTTACAGATTGCGGTGTTCGCTACCCTT
GGCTGTCTGGTGCTCGGCAGCGTCCTGGCGCTGATTCTGGTGTTTATTCCGTTTCCCGGCAGCCAACTGGTGAGCCGGGT
CATTGATACTTTTATTGCGCTGCCGACCTTTCTTATCACTCTCGCGTTCACCTTTATTTACGGCTCGGCGGGGCTGCTCA
ACGGCACCCTGATGGCGCTGTTTGCTTTTGAACTGCCGCCGGTAGACTTCCTCTATTCGATTAACGGCGTGATTCTGGCG
GAGATTACCGTCTTTACGCCGCTGGTGATGCGTCCGTTGATGGCGGGATTGCGGCAGATAGATAAGAGCCAGCTGGAAGC
GGCGAGTATTCTCGGCGCTCATCCGTTACGGGTGATTACCCAGGTTATCTTCCCGGCGGCGCTCCCGGCGCTGATGGCGG
GCGGCAGCCTGTGCCTGCTATTGACCACTAACGAGTTCGGGATCGTGCTGTTTATTGGCGCCAAAGGGGTCAATACCCTG
CCGATGATGGTCTACAGCAAGGCGATTCTGGAGTCGGATTACAGCGTGGCCTGCATGATTGCGCTGATCAATATTCTGCT
GTCGCTGGGGCTGTTTATGCTCTATCGGCTGGCGGCGGCGCGCACTGGCGTAAGGAGTTAA

Upstream 100 bases:

>100_bases
TGCGGATCGTCATGACCCACGTGAACCCGCTGCCGCGCGCGGGGGACAAGCTGGCGCTCTACTTCGAACCTGGCGATGCG
GTTCTGATCGAGGTGCAATG

Downstream 100 bases:

>100_bases
CGATGTTGATTTGGTCGCGTAAAGGCCGCGCGGCGGCGGGCGCGCTGGCGGTGACGCTTTTTGCCGGCGTTTTCCTGCTG
CCACTGGCGGTGATTTTACT

Product: 2-aminoethylphosphonate transport system memrane component

Products: ADP; phosphate; S2O32- [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 286; Mature: 285

Protein sequence:

>286_residues
MAQTLTLARPARNLRPYLWLALPLLVLATLFFYPLLLIAEQALRDASGNLSLETFWQVIDSKRFIGALLNTLQIAVFATL
GCLVLGSVLALILVFIPFPGSQLVSRVIDTFIALPTFLITLAFTFIYGSAGLLNGTLMALFAFELPPVDFLYSINGVILA
EITVFTPLVMRPLMAGLRQIDKSQLEAASILGAHPLRVITQVIFPAALPALMAGGSLCLLLTTNEFGIVLFIGAKGVNTL
PMMVYSKAILESDYSVACMIALINILLSLGLFMLYRLAAARTGVRS

Sequences:

>Translated_286_residues
MAQTLTLARPARNLRPYLWLALPLLVLATLFFYPLLLIAEQALRDASGNLSLETFWQVIDSKRFIGALLNTLQIAVFATL
GCLVLGSVLALILVFIPFPGSQLVSRVIDTFIALPTFLITLAFTFIYGSAGLLNGTLMALFAFELPPVDFLYSINGVILA
EITVFTPLVMRPLMAGLRQIDKSQLEAASILGAHPLRVITQVIFPAALPALMAGGSLCLLLTTNEFGIVLFIGAKGVNTL
PMMVYSKAILESDYSVACMIALINILLSLGLFMLYRLAAARTGVRS
>Mature_285_residues
AQTLTLARPARNLRPYLWLALPLLVLATLFFYPLLLIAEQALRDASGNLSLETFWQVIDSKRFIGALLNTLQIAVFATLG
CLVLGSVLALILVFIPFPGSQLVSRVIDTFIALPTFLITLAFTFIYGSAGLLNGTLMALFAFELPPVDFLYSINGVILAE
ITVFTPLVMRPLMAGLRQIDKSQLEAASILGAHPLRVITQVIFPAALPALMAGGSLCLLLTTNEFGIVLFIGAKGVNTLP
MMVYSKAILESDYSVACMIALINILLSLGLFMLYRLAAARTGVRS

Specific function: Probably part of the phnSTUV complex (TC 3.A.1.11.5) involved in 2-aminoethylphosphonate import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0555

COG function: function code O; ABC-type sulfate transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788764, Length=218, Percent_Identity=28.8990825688073, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787080, Length=250, Percent_Identity=26.4, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1787369, Length=184, Percent_Identity=29.8913043478261, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI87082099, Length=263, Percent_Identity=27.7566539923954, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017636
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 30968; Mature: 30837

Theoretical pI: Translated: 8.81; Mature: 8.81

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQTLTLARPARNLRPYLWLALPLLVLATLFFYPLLLIAEQALRDASGNLSLETFWQVID
CCCCCHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
SKRFIGALLNTLQIAVFATLGCLVLGSVLALILVFIPFPGSQLVSRVIDTFIALPTFLIT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
LAFTFIYGSAGLLNGTLMALFAFELPPVDFLYSINGVILAEITVFTPLVMRPLMAGLRQI
HHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
DKSQLEAASILGAHPLRVITQVIFPAALPALMAGGSLCLLLTTNEFGIVLFIGAKGVNTL
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEECCCCCCHH
PMMVYSKAILESDYSVACMIALINILLSLGLFMLYRLAAARTGVRS
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
AQTLTLARPARNLRPYLWLALPLLVLATLFFYPLLLIAEQALRDASGNLSLETFWQVID
CCCCHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
SKRFIGALLNTLQIAVFATLGCLVLGSVLALILVFIPFPGSQLVSRVIDTFIALPTFLIT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
LAFTFIYGSAGLLNGTLMALFAFELPPVDFLYSINGVILAEITVFTPLVMRPLMAGLRQI
HHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
DKSQLEAASILGAHPLRVITQVIFPAALPALMAGGSLCLLLTTNEFGIVLFIGAKGVNTL
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEECCCCCCHH
PMMVYSKAILESDYSVACMIALINILLSLGLFMLYRLAAARTGVRS
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; S2O32- [Periplasm]; H2O; SO42- [Periplasm]; ATP [C]

Specific reaction: ATP + S2O32- [Periplasm] + H2O = ADP + phosphate + S2O32- [Cytoplasm] SO42- [Periplasm] + H2O + ATP = SO42- [Cytoplasm] + phosphate + ADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA