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The map label for this gene is licC [H]

Identifier: 238897161

GI number: 238897161

Start: 5160670

End: 5161992

Strand: Direct

Name: licC [H]

Synonym: KP1_5425

Alternate gene names: 238897161

Gene position: 5160670-5161992 (Clockwise)

Preceding gene: 238897160

Following gene: 238897162

Centisome position: 98.33

GC content: 57.22

Gene sequence:

>1323_bases
ATGAGTTCTCTGTATCAGTCCATGATTGCCGTGATCGAGCAATCTATTACTCCGCTGGCAGGACGCCTTGGGCAGCAGAA
ATACGTTATCGCTATCCGCGATGGCTTCACTGCCGCCTTGCCGTTTATGATCATCGGCTCTTTCATGCTGGTATTTATCT
TTCCGCCGTTTTCACCCGATACCACCAACGGCTTTGCCCGCGGCTGGCTTGATTTCTCCCAGCACTACCGCGAACAGCTG
ATGCTGCCGTTTAACCTCAGCATGGGCGTGATGACCTTCTTTATCTCGGTCGGCATTGGCGCCAGCCTCGGTCGTCAGTT
TCAGCTCGATCCGGTGATGTCCGGTCTGCTGGCGTTTATGGCTTTCCTGCTGGTCGCCGCGCCCTATGCCGATGGCAAAA
TTTCCACTCAGTATCTGTCCGGTCAGGGCATTTTCACCGCGCTGATCACCGCCATCTACTCCACCCGCGTTTACGCGTGG
CTGAAGCAAAACAACATTACGATTCGTCTGCCGAAAGAGGTCCCCACCGGCGTCGCCCGTTCGTTTGAAATCCTGATCCC
GGTGCTGGTGGTTATTGCGACTCTGCATCCGCTGAATCTGTTTATCGAAGCGCAGACCGGGATGATCCTGCCGCAGGCGA
TCATGCATCTGCTGGAGCCGCTGGTTTCCGCCTCCGACTCGCTGCCGGCGATTTTGCTCTCTGTTCTGATGTGCCAGATT
TTCTGGTTCGCCGGTATCCACGGCTCGCTGATTGTTACCGGCATTATGAACCCGTTCTGGATGGCCAACCTGTCGGCAAA
CCAGGCGGCGCTGGCGGCTGGCACGGTACTGCCGCACGTCTACCTGCAGGGCTTCTGGGATCACTATCTGCTGATTGGCG
GCGTCGGTTCTACCCTGCCGCTGGCCTTCCTGCTGCTGCGTAGCCGGGCCACCCATCTGCGCACCATCGGCAAGATGGGC
ATCGTGCCGAGCTTCTTTAATATCAACGAGCCGATTCTGTTCGGGGCGCCGATCATCATGAACCCGATGATGTTTATCCC
CTTCGTCTGCGTACCGATGGTCAACGCGGTGTTGGCTTACGGCGCGACGCGTCTTGGCTGGCTGAGCCAGGTGGTCTCGC
TGACGCCGTGGACTACGCCGGCCCCAATTGGCGCGTCGTGGGCGGCTAACTGGACCCTGAGCCCGGTGGTGATGTGTCTC
ATCTGCATGGTGATGTCGGCGGTCATTTACCTGCCGTTCCTGCGCGCTTATGAACGTTCCTTAATGAAAACCGAAGTTGA
GAAAGCCAAAAATAGCGTTCCGGTAGCAGAAACCGTTAGCTAA

Upstream 100 bases:

>100_bases
TTCAGCCCATCGATACGATGGACTACGGTATGCAGCGGGGAGACAACGTCCTGAATTATGCTCTGTCGCTGATCCCAGCG
GCGCACTGAGAGGTGTTGAA

Downstream 100 bases:

>100_bases
TCCCTCTCCTTCCGGAGAGATAATAAGATGACAGCGTAATAATGCAGAAAATGGACTTTCACTGCATTATTAAATAATAA
ATACCTCAGGAATACACATG

Product: putative PTS family enzyme IIC component

Products: protein histidine; sugar phosphate

Alternate protein names: EIIC-Lic; PTS system lichenan-specific EIIC component [H]

Number of amino acids: Translated: 440; Mature: 439

Protein sequence:

>440_residues
MSSLYQSMIAVIEQSITPLAGRLGQQKYVIAIRDGFTAALPFMIIGSFMLVFIFPPFSPDTTNGFARGWLDFSQHYREQL
MLPFNLSMGVMTFFISVGIGASLGRQFQLDPVMSGLLAFMAFLLVAAPYADGKISTQYLSGQGIFTALITAIYSTRVYAW
LKQNNITIRLPKEVPTGVARSFEILIPVLVVIATLHPLNLFIEAQTGMILPQAIMHLLEPLVSASDSLPAILLSVLMCQI
FWFAGIHGSLIVTGIMNPFWMANLSANQAALAAGTVLPHVYLQGFWDHYLLIGGVGSTLPLAFLLLRSRATHLRTIGKMG
IVPSFFNINEPILFGAPIIMNPMMFIPFVCVPMVNAVLAYGATRLGWLSQVVSLTPWTTPAPIGASWAANWTLSPVVMCL
ICMVMSAVIYLPFLRAYERSLMKTEVEKAKNSVPVAETVS

Sequences:

>Translated_440_residues
MSSLYQSMIAVIEQSITPLAGRLGQQKYVIAIRDGFTAALPFMIIGSFMLVFIFPPFSPDTTNGFARGWLDFSQHYREQL
MLPFNLSMGVMTFFISVGIGASLGRQFQLDPVMSGLLAFMAFLLVAAPYADGKISTQYLSGQGIFTALITAIYSTRVYAW
LKQNNITIRLPKEVPTGVARSFEILIPVLVVIATLHPLNLFIEAQTGMILPQAIMHLLEPLVSASDSLPAILLSVLMCQI
FWFAGIHGSLIVTGIMNPFWMANLSANQAALAAGTVLPHVYLQGFWDHYLLIGGVGSTLPLAFLLLRSRATHLRTIGKMG
IVPSFFNINEPILFGAPIIMNPMMFIPFVCVPMVNAVLAYGATRLGWLSQVVSLTPWTTPAPIGASWAANWTLSPVVMCL
ICMVMSAVIYLPFLRAYERSLMKTEVEKAKNSVPVAETVS
>Mature_439_residues
SSLYQSMIAVIEQSITPLAGRLGQQKYVIAIRDGFTAALPFMIIGSFMLVFIFPPFSPDTTNGFARGWLDFSQHYREQLM
LPFNLSMGVMTFFISVGIGASLGRQFQLDPVMSGLLAFMAFLLVAAPYADGKISTQYLSGQGIFTALITAIYSTRVYAWL
KQNNITIRLPKEVPTGVARSFEILIPVLVVIATLHPLNLFIEAQTGMILPQAIMHLLEPLVSASDSLPAILLSVLMCQIF
WFAGIHGSLIVTGIMNPFWMANLSANQAALAAGTVLPHVYLQGFWDHYLLIGGVGSTLPLAFLLLRSRATHLRTIGKMGI
VPSFFNINEPILFGAPIIMNPMMFIPFVCVPMVNAVLAYGATRLGWLSQVVSLTPWTTPAPIGASWAANWTLSPVVMCLI
CMVMSAVIYLPFLRAYERSLMKTEVEKAKNSVPVAETVS

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system i

COG id: COG1455

COG function: function code G; Phosphotransferase system cellobiose-specific component IIC

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-3 domain [H]

Homologues:

Organism=Escherichia coli, GI1788032, Length=459, Percent_Identity=30.0653594771242, Blast_Score=188, Evalue=7e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003352
- InterPro:   IPR004796
- InterPro:   IPR004501 [H]

Pfam domain/function: PF02378 PTS_EIIC [H]

EC number: 2.7.1.69

Molecular weight: Translated: 48196; Mature: 48065

Theoretical pI: Translated: 8.82; Mature: 8.82

Prosite motif: PS51105 PTS_EIIC_TYPE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSLYQSMIAVIEQSITPLAGRLGQQKYVIAIRDGFTAALPFMIIGSFMLVFIFPPFSPD
CCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCC
TTNGFARGWLDFSQHYREQLMLPFNLSMGVMTFFISVGIGASLGRQFQLDPVMSGLLAFM
CCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCHHCCCCEEHHHHHHHHHHHH
AFLLVAAPYADGKISTQYLSGQGIFTALITAIYSTRVYAWLKQNNITIRLPKEVPTGVAR
HHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHEEEECCCEEEEECCCCCCHHHH
SFEILIPVLVVIATLHPLNLFIEAQTGMILPQAIMHLLEPLVSASDSLPAILLSVLMCQI
HHHHHHHHHHHHHHHCHHHEEEECCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
FWFAGIHGSLIVTGIMNPFWMANLSANQAALAAGTVLPHVYLQGFWDHYLLIGGVGSTLP
HHHHCCCCHHHHHHHCCCHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHH
LAFLLLRSRATHLRTIGKMGIVPSFFNINEPILFGAPIIMNPMMFIPFVCVPMVNAVLAY
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCHHHHCCHHHHHHHHHHHHHHHHHH
GATRLGWLSQVVSLTPWTTPAPIGASWAANWTLSPVVMCLICMVMSAVIYLPFLRAYERS
CCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LMKTEVEKAKNSVPVAETVS
HHHHHHHHHHCCCCCHHCCC
>Mature Secondary Structure 
SSLYQSMIAVIEQSITPLAGRLGQQKYVIAIRDGFTAALPFMIIGSFMLVFIFPPFSPD
CHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCC
TTNGFARGWLDFSQHYREQLMLPFNLSMGVMTFFISVGIGASLGRQFQLDPVMSGLLAFM
CCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCHHCCCCEEHHHHHHHHHHHH
AFLLVAAPYADGKISTQYLSGQGIFTALITAIYSTRVYAWLKQNNITIRLPKEVPTGVAR
HHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHEEEECCCEEEEECCCCCCHHHH
SFEILIPVLVVIATLHPLNLFIEAQTGMILPQAIMHLLEPLVSASDSLPAILLSVLMCQI
HHHHHHHHHHHHHHHCHHHEEEECCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
FWFAGIHGSLIVTGIMNPFWMANLSANQAALAAGTVLPHVYLQGFWDHYLLIGGVGSTLP
HHHHCCCCHHHHHHHCCCHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHH
LAFLLLRSRATHLRTIGKMGIVPSFFNINEPILFGAPIIMNPMMFIPFVCVPMVNAVLAY
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCHHHHCCHHHHHHHHHHHHHHHHHH
GATRLGWLSQVVSLTPWTTPAPIGASWAANWTLSPVVMCLICMVMSAVIYLPFLRAYERS
CCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LMKTEVEKAKNSVPVAETVS
HHHHHHHHHHCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: protein N(pi)-phosphohistidine; sugar

Specific reaction: protein N(pi)-phosphohistidine + sugar = protein histidine + sugar phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8990303; 8969509; 9384377 [H]