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The map label for this gene is fpr [H]

Identifier: 238897104

GI number: 238897104

Start: 5099424

End: 5100170

Strand: Direct

Name: fpr [H]

Synonym: KP1_5359

Alternate gene names: 238897104

Gene position: 5099424-5100170 (Clockwise)

Preceding gene: 238897103

Following gene: 238897106

Centisome position: 97.16

GC content: 61.18

Gene sequence:

>747_bases
ATGGCGGACTGGGTTAGCGGCAAAGTGACAAAAGTGGAGTACTGGACGGACGCCTTGTTCAGTTTATACGTGCGGGCGCC
TGTTCATCCGTTTACCGCCGGGCAATTTACCAAGCTCGGGCTGGAAATCGACGGCGAACGCGTGCAGCGCGCCTACTCCT
ACGTCAACGCCCCCGGCAATCCCGACCTCGAGTTCTATTTGGTCACCGTCCCGGAAGGCAAGCTGAGCCCGCGTCTGGCG
GCGCTGAAGCCGGGCGATGAAGTCCTGGTGGTGAGTGAAGCGGCAGGTTTCTTCGTCCTCGAGGAGGTACCGGATTGCGA
TACCCTGTGGATGCTGGCGACCGGCACTGCGCTGGGGCCGTACCTGTCAATTTTGCAGGAAGGCAAGGACCTTGAGCGCT
TTAACAACCTGGTGCTGGTCCACGCCGTCCGCTACGCCGCGGACCTGAGCTATCTGCCGCTAATGCGCGAACTGGAGCAG
CGCTATGCCGGCAAACTCCGTATTCAGACGGTGATCAGCCGCGAAACCGTGGAAGGCTCGCTGACCGGCCGGGTGCCGTT
TCTGATTGAAACCGGCGCGCTGGAAGAGGCCGTCGGCCTGCCGATGACCACCGACACCAGCCATGTGATGCTGTGCGGCA
ACCCGCAAATGGTGCGCGATACCCAACAGCTGTTAAAAGAGACCCGGCAGATGACCAAACATCTGCGTCGCCGGCCGGGC
CATATGACGGCGGAGCACTACTGGTAA

Upstream 100 bases:

>100_bases
TCGTTTATATTTGATCAATAGAGCTTTCTTGCGCCTTCGGGGTGGAAATCTGGCTCGTCTGGACCGAAGATAAGGCATCG
CTTGGCAACAGGAGAAGACG

Downstream 100 bases:

>100_bases
TCAGGCGTCCGCTTTCCAGCGCACGTCCTGGGTCTCCTTGCCGAACTTATTCTCGCCCTGGGTGCCGACAAACGCCCCCA
GGTCGATCAGCATCATGACG

Product: ferredoxin-NADP reductase

Products: NA

Alternate protein names: FNR; DA1; Flavodoxin reductase; FLDR; FLXR; Methyl viologen resistance protein A [H]

Number of amino acids: Translated: 248; Mature: 247

Protein sequence:

>248_residues
MADWVSGKVTKVEYWTDALFSLYVRAPVHPFTAGQFTKLGLEIDGERVQRAYSYVNAPGNPDLEFYLVTVPEGKLSPRLA
ALKPGDEVLVVSEAAGFFVLEEVPDCDTLWMLATGTALGPYLSILQEGKDLERFNNLVLVHAVRYAADLSYLPLMRELEQ
RYAGKLRIQTVISRETVEGSLTGRVPFLIETGALEEAVGLPMTTDTSHVMLCGNPQMVRDTQQLLKETRQMTKHLRRRPG
HMTAEHYW

Sequences:

>Translated_248_residues
MADWVSGKVTKVEYWTDALFSLYVRAPVHPFTAGQFTKLGLEIDGERVQRAYSYVNAPGNPDLEFYLVTVPEGKLSPRLA
ALKPGDEVLVVSEAAGFFVLEEVPDCDTLWMLATGTALGPYLSILQEGKDLERFNNLVLVHAVRYAADLSYLPLMRELEQ
RYAGKLRIQTVISRETVEGSLTGRVPFLIETGALEEAVGLPMTTDTSHVMLCGNPQMVRDTQQLLKETRQMTKHLRRRPG
HMTAEHYW
>Mature_247_residues
ADWVSGKVTKVEYWTDALFSLYVRAPVHPFTAGQFTKLGLEIDGERVQRAYSYVNAPGNPDLEFYLVTVPEGKLSPRLAA
LKPGDEVLVVSEAAGFFVLEEVPDCDTLWMLATGTALGPYLSILQEGKDLERFNNLVLVHAVRYAADLSYLPLMRELEQR
YAGKLRIQTVISRETVEGSLTGRVPFLIETGALEEAVGLPMTTDTSHVMLCGNPQMVRDTQQLLKETRQMTKHLRRRPGH
MTAEHYW

Specific function: Transports electrons between flavodoxin or ferredoxin and NADPH. Involved in the reductive activation of cobalamin- independent methionine synthase, pyruvate formate lyase and anaerobic ribonucleotide reductase. Also protects against superoxide radicals d

COG id: COG1018

COG function: function code C; Flavodoxin reductases (ferredoxin-NADPH reductases) family 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Escherichia coli, GI1790359, Length=248, Percent_Identity=86.2903225806452, Blast_Score=449, Evalue=1e-128,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017927
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00175 NAD_binding_1 [H]

EC number: =1.18.1.2 [H]

Molecular weight: Translated: 27871; Mature: 27740

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADWVSGKVTKVEYWTDALFSLYVRAPVHPFTAGQFTKLGLEIDGERVQRAYSYVNAPGN
CCCCCCCCEEEEHHHHHHHHHHHHHCCCCCCCCCCEEEECEEECHHHHHHHHHHHCCCCC
PDLEFYLVTVPEGKLSPRLAALKPGDEVLVVSEAAGFFVLEEVPDCDTLWMLATGTALGP
CCEEEEEEECCCCCCCCCEEEECCCCCEEEEECCCCEEEEECCCCCCEEEEEECCCHHHH
YLSILQEGKDLERFNNLVLVHAVRYAADLSYLPLMRELEQRYAGKLRIQTVISRETVEGS
HHHHHHCCCHHHHHCCEEEEEHHHHHHCCHHHHHHHHHHHHHCCCEEEEEEHHHHHCCCC
LTGRVPFLIETGALEEAVGLPMTTDTSHVMLCGNPQMVRDTQQLLKETRQMTKHLRRRPG
CCCCCCEEEECCCHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCC
HMTAEHYW
CCCCCCCC
>Mature Secondary Structure 
ADWVSGKVTKVEYWTDALFSLYVRAPVHPFTAGQFTKLGLEIDGERVQRAYSYVNAPGN
CCCCCCCEEEEHHHHHHHHHHHHHCCCCCCCCCCEEEECEEECHHHHHHHHHHHCCCCC
PDLEFYLVTVPEGKLSPRLAALKPGDEVLVVSEAAGFFVLEEVPDCDTLWMLATGTALGP
CCEEEEEEECCCCCCCCCEEEECCCCCEEEEECCCCEEEEECCCCCCEEEEEECCCHHHH
YLSILQEGKDLERFNNLVLVHAVRYAADLSYLPLMRELEQRYAGKLRIQTVISRETVEGS
HHHHHHCCCHHHHHCCEEEEEHHHHHHCCHHHHHHHHHHHHHCCCEEEEEEHHHHHCCCC
LTGRVPFLIETGALEEAVGLPMTTDTSHVMLCGNPQMVRDTQQLLKETRQMTKHLRRRPG
CCCCCCEEEECCCHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCC
HMTAEHYW
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8449868; 8346018; 9278503; 1400248; 2834327; 7961651; 9149148 [H]