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The map label for this gene is gpsA [H]

Identifier: 238897052

GI number: 238897052

Start: 5048335

End: 5049354

Strand: Reverse

Name: gpsA [H]

Synonym: KP1_5301

Alternate gene names: 238897052

Gene position: 5049354-5048335 (Counterclockwise)

Preceding gene: 238897053

Following gene: 238897051

Centisome position: 96.21

GC content: 61.37

Gene sequence:

>1020_bases
ATGAACGCACTTAATGCTGCAATGACTGTGATCGGTGCCGGCTCTTACGGCACCGCTCTTGCCATCACCCTGGCAAGAAA
TGGCCACCACGTTGTGCTGTGGGGCCATGACCCGAAACATATCGCGACGCTGCAACACGATCGCTGCAACGCCGCGTTCC
TTCCCGATGTGCCTTTCCCGGATACGCTGCATCTTGAGAGCGACCTGGCCACCGCGCTGGCCGCCAGCCGCGACATCCTT
GTCGTGGTGCCGAGCCATGTATTCGGTCAGGTGTTACGCCAGATTAAACCGCTGATGCGTTCCGACGCGCGGCTGGTGTG
GGCCACCAAAGGCCTGGAGGCCGAAACCGGCCGTCTGCTGCAGGACGTGGCGCGTGAAGCGCTGGGCGATGATATTCCGC
TGGCGGTGATCTCGGGGCCAACCTTCGCCAAAGAGCTGGCCGCCGGCCTGCCGACGGCGATTTCGCTGGCGGCCACGGAT
CCGCAGTTTGCGGAAGACCTTCAGCGCCTACTGCACTGCGGCAAAAGCTTCCGCGTCTACATCAACCCGGACTTTATCGG
CGTGCAGCTCGGCGGCGCGGTGAAAAACGTCATTGCCATCGGGGCAGGTATGTCGGACGGCATCGGCTTCGGCGCCAATG
CGCGTACGGCGCTGATTACCCGTGGGCTGGTGGAAATGTCCCGCCTCGGCGCGGCGCTGGGCGCCGATCCGGAAACCTTT
ATGGGCATGGCCGGCCTCGGTGACCTGGTGCTCACCTGCACCGACAACCAGTCCCGTAACCGTCGCTTCGGCATGATGCT
CGGCCAGGGTATGGACGTGCAGAGCGCCCAGGACAAGATTGGCCAGGTGGTTGAAGGCTACCGCAATACCAAGGAAGTTC
GCGTTCTGGCACAGCGTTTAGGTGTCGAAATGCCAATAACCGAGGAAATTTATCAGGTATTGTATTGCGGAAAAATTGCG
CGCGAGGCAGCATTGACCTTATTGGGTCGCGCCCGCAAGGACGAGCGCAGCAGCAATTAG

Upstream 100 bases:

>100_bases
TCCCGCAACTTAACCTTGCGCCAGTGAACTTCGACGCGCTGTTCATGAACTATCTGCAGCAGCAGGCTGGCGAAGGTGCT
GAACAACATCAGGATGCCTG

Downstream 100 bases:

>100_bases
CTTTCCTTTGTCACCTGAATGACCCTGCCAGCGCAGAACTGGCAGGTCATTACTATATCGCCTGGAGTATGCAATGCCGT
GTGAAGAACTGGATATCGTC

Product: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase [H]

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MNALNAAMTVIGAGSYGTALAITLARNGHHVVLWGHDPKHIATLQHDRCNAAFLPDVPFPDTLHLESDLATALAASRDIL
VVVPSHVFGQVLRQIKPLMRSDARLVWATKGLEAETGRLLQDVAREALGDDIPLAVISGPTFAKELAAGLPTAISLAATD
PQFAEDLQRLLHCGKSFRVYINPDFIGVQLGGAVKNVIAIGAGMSDGIGFGANARTALITRGLVEMSRLGAALGADPETF
MGMAGLGDLVLTCTDNQSRNRRFGMMLGQGMDVQSAQDKIGQVVEGYRNTKEVRVLAQRLGVEMPITEEIYQVLYCGKIA
REAALTLLGRARKDERSSN

Sequences:

>Translated_339_residues
MNALNAAMTVIGAGSYGTALAITLARNGHHVVLWGHDPKHIATLQHDRCNAAFLPDVPFPDTLHLESDLATALAASRDIL
VVVPSHVFGQVLRQIKPLMRSDARLVWATKGLEAETGRLLQDVAREALGDDIPLAVISGPTFAKELAAGLPTAISLAATD
PQFAEDLQRLLHCGKSFRVYINPDFIGVQLGGAVKNVIAIGAGMSDGIGFGANARTALITRGLVEMSRLGAALGADPETF
MGMAGLGDLVLTCTDNQSRNRRFGMMLGQGMDVQSAQDKIGQVVEGYRNTKEVRVLAQRLGVEMPITEEIYQVLYCGKIA
REAALTLLGRARKDERSSN
>Mature_339_residues
MNALNAAMTVIGAGSYGTALAITLARNGHHVVLWGHDPKHIATLQHDRCNAAFLPDVPFPDTLHLESDLATALAASRDIL
VVVPSHVFGQVLRQIKPLMRSDARLVWATKGLEAETGRLLQDVAREALGDDIPLAVISGPTFAKELAAGLPTAISLAATD
PQFAEDLQRLLHCGKSFRVYINPDFIGVQLGGAVKNVIAIGAGMSDGIGFGANARTALITRGLVEMSRLGAALGADPETF
MGMAGLGDLVLTCTDNQSRNRRFGMMLGQGMDVQSAQDKIGQVVEGYRNTKEVRVLAQRLGVEMPITEEIYQVLYCGKIA
REAALTLLGRARKDERSSN

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI33695088, Length=336, Percent_Identity=28.8690476190476, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI24307999, Length=337, Percent_Identity=26.7062314540059, Blast_Score=110, Evalue=3e-24,
Organism=Escherichia coli, GI1790037, Length=339, Percent_Identity=92.6253687315634, Blast_Score=639, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17507425, Length=345, Percent_Identity=23.4782608695652, Blast_Score=98, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI32564399, Length=334, Percent_Identity=24.8502994011976, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI193210136, Length=343, Percent_Identity=23.9067055393586, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI32564403, Length=343, Percent_Identity=23.9067055393586, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI193210134, Length=206, Percent_Identity=28.1553398058252, Blast_Score=76, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6320181, Length=344, Percent_Identity=28.4883720930233, Blast_Score=108, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6324513, Length=342, Percent_Identity=26.6081871345029, Blast_Score=104, Evalue=2e-23,
Organism=Drosophila melanogaster, GI17136204, Length=335, Percent_Identity=27.4626865671642, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI17136202, Length=335, Percent_Identity=27.4626865671642, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI17136200, Length=335, Percent_Identity=27.4626865671642, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI22026922, Length=271, Percent_Identity=23.2472324723247, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI45551945, Length=239, Percent_Identity=29.2887029288703, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI281362270, Length=239, Percent_Identity=29.2887029288703, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24648969, Length=184, Percent_Identity=31.5217391304348, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040 [H]

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N [H]

EC number: =1.1.1.94 [H]

Molecular weight: Translated: 36233; Mature: 36233

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: PS00957 NAD_G3PDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNALNAAMTVIGAGSYGTALAITLARNGHHVVLWGHDPKHIATLQHDRCNAAFLPDVPFP
CCHHHHHHHEEECCCCCCEEEEEEECCCCEEEEECCCCCHHEEECCCCCCEEECCCCCCC
DTLHLESDLATALAASRDILVVVPSHVFGQVLRQIKPLMRSDARLVWATKGLEAETGRLL
CCEECHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHH
QDVAREALGDDIPLAVISGPTFAKELAAGLPTAISLAATDPQFAEDLQRLLHCGKSFRVY
HHHHHHHCCCCCCEEEECCCHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHCCCCEEEE
INPDFIGVQLGGAVKNVIAIGAGMSDGIGFGANARTALITRGLVEMSRLGAALGADPETF
ECCCEEEEEECHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHH
MGMAGLGDLVLTCTDNQSRNRRFGMMLGQGMDVQSAQDKIGQVVEGYRNTKEVRVLAQRL
HHHCCCCCEEEEECCCCCCCCEEHHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHH
GVEMPITEEIYQVLYCGKIAREAALTLLGRARKDERSSN
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MNALNAAMTVIGAGSYGTALAITLARNGHHVVLWGHDPKHIATLQHDRCNAAFLPDVPFP
CCHHHHHHHEEECCCCCCEEEEEEECCCCEEEEECCCCCHHEEECCCCCCEEECCCCCCC
DTLHLESDLATALAASRDILVVVPSHVFGQVLRQIKPLMRSDARLVWATKGLEAETGRLL
CCEECHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHH
QDVAREALGDDIPLAVISGPTFAKELAAGLPTAISLAATDPQFAEDLQRLLHCGKSFRVY
HHHHHHHCCCCCCEEEECCCHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHCCCCEEEE
INPDFIGVQLGGAVKNVIAIGAGMSDGIGFGANARTALITRGLVEMSRLGAALGADPETF
ECCCEEEEEECHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHH
MGMAGLGDLVLTCTDNQSRNRRFGMMLGQGMDVQSAQDKIGQVVEGYRNTKEVRVLAQRL
HHHCCCCCEEEEECCCCCCCCEEHHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHH
GVEMPITEEIYQVLYCGKIAREAALTLLGRARKDERSSN
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA