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The map label for this gene is xylH [H]

Identifier: 238897033

GI number: 238897033

Start: 5025392

End: 5026573

Strand: Direct

Name: xylH [H]

Synonym: KP1_5280

Alternate gene names: 238897033

Gene position: 5025392-5026573 (Clockwise)

Preceding gene: 238897032

Following gene: 238897034

Centisome position: 95.75

GC content: 63.62

Gene sequence:

>1182_bases
ATGTCGAAGAACACGTCGTCTGAAATCAAACTCACCCCAACCGCCCCCGCGGCCCTGCCGGCGCTGAAGGGGCTGAATCT
CCAGGTCTTCGTGATGATCGCCGCCATCGTCGTCATTATGCTGTTTTTCACCTGGGTTACCGATGGCGCCTACCTGAGCG
CACGCAATATCTCCAACCTGCTGCGGCAGACGGCCATCACCGGCATCCTCGCCGTCGGCATGGTGTTTGTGATTATTTCG
GCAGAAATCGACCTCTCCGTTGGCTCGATGATGGGGCTGCTGGGCGGCGCTGCGGCGATCTTTGACGTCTGGCTCGGCTG
GCCGCTGCCGCTCACCATTCTGGTGACGCTGGTGATGGGCCTGCTGCTCGGGGCGTGGAACGGATGGTGGGTAGCCTATC
GCAAAGTGCCCTCGTTTATCGTCACCCTTGCCGGGATGCTGGCGTTTCGCGGCATTCTGATCGGCATCACCAACGGGACC
ACCGTCTCGCCCACCAGTCCGGCGATGTCGCAGATCGGCCAAAGCTACCTGCCAGACGGCATCGGCTTCGGCATCGGCGT
TGTCGGCATGGCGGTGTTTATCGTCTGGCAGTGGCGCGGGCGGATGCGCCGGCAGGCGTTAGGTCTGGCGACCTCGTCCT
CCACCGCCGCCGTCGGCCGCCAGGCCATTACCGCGGTGATTGTGCTGGGCGCAATCTGGCTGCTCAATGACTATCGCGGC
GTACCGACCCCGGTGCTGATCCTCGCCGCCCTGCTGCTGGCGGGCCTGTTTATGGCCACCCGCACCGCCTTTGGTCGCCG
CATCTACGCCATCGGCGGCAACCTGGAGGCGGCCCGTCTGTCCGGGATTAACGTCGAGCGTACCAAGCTGGCGGTGTTTG
CCATTAACGGCCTGATGGTCGCTATTGCCGGGCTAATCCTCAGCTCACGGCTCGGCGCGGGGTCGCCTTCGGCGGGCAAT
ATCGCCGAACTGGACGCCATCGCCGCCTGCGTCATCGGCGGCACCAGCCTGGCGGGCGGCATCGGCAGCGTCGCCGGGGC
GGTAATGGGGGCGTTTATTATGTCGGCCCTGGATAACGGTATGAGCATGATGGACGTCGCCACCTTCTGGCAATATATCG
TTAAAGGCGCCATTTTGCTGCTGGCGGTGTGGATGGACTCTGCCACCAAGCGGCGCGCATAA

Upstream 100 bases:

>100_bases
CGGGTGCTGGTCATGCACGAAGGCAGACTAAAAGCCAATTTGGTTAATCAACATCTGACCCAGGAACAGGTGATGGAAGC
CGCGCTGAGGAGCGAACGCC

Downstream 100 bases:

>100_bases
GGAGAGACTCTCTGAAGAATGTCTGAATTCTTTGCGCTACCGCCAAACTTCGCCATAAGGCGCTTGAAATATCTCGGGCA
TTAGCCGGTAGTGTATACCC

Product: D-xylose transport system permease component

Products: ADP; phosphate; xylose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 393; Mature: 392

Protein sequence:

>393_residues
MSKNTSSEIKLTPTAPAALPALKGLNLQVFVMIAAIVVIMLFFTWVTDGAYLSARNISNLLRQTAITGILAVGMVFVIIS
AEIDLSVGSMMGLLGGAAAIFDVWLGWPLPLTILVTLVMGLLLGAWNGWWVAYRKVPSFIVTLAGMLAFRGILIGITNGT
TVSPTSPAMSQIGQSYLPDGIGFGIGVVGMAVFIVWQWRGRMRRQALGLATSSSTAAVGRQAITAVIVLGAIWLLNDYRG
VPTPVLILAALLLAGLFMATRTAFGRRIYAIGGNLEAARLSGINVERTKLAVFAINGLMVAIAGLILSSRLGAGSPSAGN
IAELDAIAACVIGGTSLAGGIGSVAGAVMGAFIMSALDNGMSMMDVATFWQYIVKGAILLLAVWMDSATKRRA

Sequences:

>Translated_393_residues
MSKNTSSEIKLTPTAPAALPALKGLNLQVFVMIAAIVVIMLFFTWVTDGAYLSARNISNLLRQTAITGILAVGMVFVIIS
AEIDLSVGSMMGLLGGAAAIFDVWLGWPLPLTILVTLVMGLLLGAWNGWWVAYRKVPSFIVTLAGMLAFRGILIGITNGT
TVSPTSPAMSQIGQSYLPDGIGFGIGVVGMAVFIVWQWRGRMRRQALGLATSSSTAAVGRQAITAVIVLGAIWLLNDYRG
VPTPVLILAALLLAGLFMATRTAFGRRIYAIGGNLEAARLSGINVERTKLAVFAINGLMVAIAGLILSSRLGAGSPSAGN
IAELDAIAACVIGGTSLAGGIGSVAGAVMGAFIMSALDNGMSMMDVATFWQYIVKGAILLLAVWMDSATKRRA
>Mature_392_residues
SKNTSSEIKLTPTAPAALPALKGLNLQVFVMIAAIVVIMLFFTWVTDGAYLSARNISNLLRQTAITGILAVGMVFVIISA
EIDLSVGSMMGLLGGAAAIFDVWLGWPLPLTILVTLVMGLLLGAWNGWWVAYRKVPSFIVTLAGMLAFRGILIGITNGTT
VSPTSPAMSQIGQSYLPDGIGFGIGVVGMAVFIVWQWRGRMRRQALGLATSSSTAAVGRQAITAVIVLGAIWLLNDYRGV
PTPVLILAALLLAGLFMATRTAFGRRIYAIGGNLEAARLSGINVERTKLAVFAINGLMVAIAGLILSSRLGAGSPSAGNI
AELDAIAACVIGGTSLAGGIGSVAGAVMGAFIMSALDNGMSMMDVATFWQYIVKGAILLLAVWMDSATKRRA

Specific function: Part of the binding-protein-dependent transport system for D-xylose. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4214

COG function: function code G; ABC-type xylose transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. AraH/rbsC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789992, Length=393, Percent_Identity=86.7684478371501, Blast_Score=622, Evalue=1e-179,
Organism=Escherichia coli, GI1790191, Length=359, Percent_Identity=35.6545961002786, Blast_Score=171, Evalue=8e-44,
Organism=Escherichia coli, GI1788896, Length=161, Percent_Identity=39.7515527950311, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI145693152, Length=341, Percent_Identity=31.6715542521994, Blast_Score=132, Evalue=5e-32,
Organism=Escherichia coli, GI87082395, Length=339, Percent_Identity=30.9734513274336, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1790524, Length=152, Percent_Identity=39.4736842105263, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1788471, Length=133, Percent_Identity=44.3609022556391, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI145693214, Length=304, Percent_Identity=32.2368421052632, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1787793, Length=163, Percent_Identity=36.1963190184049, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1787794, Length=156, Percent_Identity=31.4102564102564, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 40979; Mature: 40847

Theoretical pI: Translated: 10.82; Mature: 10.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKNTSSEIKLTPTAPAALPALKGLNLQVFVMIAAIVVIMLFFTWVTDGAYLSARNISNL
CCCCCCCCEEECCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHH
LRQTAITGILAVGMVFVIISAEIDLSVGSMMGLLGGAAAIFDVWLGWPLPLTILVTLVMG
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
LLLGAWNGWWVAYRKVPSFIVTLAGMLAFRGILIGITNGTTVSPTSPAMSQIGQSYLPDG
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCHHHHHCCHHHCCCC
IGFGIGVVGMAVFIVWQWRGRMRRQALGLATSSSTAAVGRQAITAVIVLGAIWLLNDYRG
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
VPTPVLILAALLLAGLFMATRTAFGRRIYAIGGNLEAARLSGINVERTKLAVFAINGLMV
CCHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHCCCCCCCHHEEEEHHHHHHHH
AIAGLILSSRLGAGSPSAGNIAELDAIAACVIGGTSLAGGIGSVAGAVMGAFIMSALDNG
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCHHHCHHHHHHHHHHHHHHHHHHHCC
MSMMDVATFWQYIVKGAILLLAVWMDSATKRRA
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCC
>Mature Secondary Structure 
SKNTSSEIKLTPTAPAALPALKGLNLQVFVMIAAIVVIMLFFTWVTDGAYLSARNISNL
CCCCCCCEEECCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHH
LRQTAITGILAVGMVFVIISAEIDLSVGSMMGLLGGAAAIFDVWLGWPLPLTILVTLVMG
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
LLLGAWNGWWVAYRKVPSFIVTLAGMLAFRGILIGITNGTTVSPTSPAMSQIGQSYLPDG
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCHHHHHCCHHHCCCC
IGFGIGVVGMAVFIVWQWRGRMRRQALGLATSSSTAAVGRQAITAVIVLGAIWLLNDYRG
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
VPTPVLILAALLLAGLFMATRTAFGRRIYAIGGNLEAARLSGINVERTKLAVFAINGLMV
CCHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHCCCCCCCHHEEEEHHHHHHHH
AIAGLILSSRLGAGSPSAGNIAELDAIAACVIGGTSLAGGIGSVAGAVMGAFIMSALDNG
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCHHHCHHHHHHHHHHHHHHHHHHHCC
MSMMDVATFWQYIVKGAILLLAVWMDSATKRRA
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; xylose [Periplasm]; H2O [C]

Specific reaction: ATP + xylose [Periplasm] + H2O = ADP + phosphate + xylose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]