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The map label for this gene is tag [H]

Identifier: 238897007

GI number: 238897007

Start: 4998109

End: 4998840

Strand: Direct

Name: tag [H]

Synonym: KP1_5252

Alternate gene names: 238897007

Gene position: 4998109-4998840 (Clockwise)

Preceding gene: 238897002

Following gene: 238897008

Centisome position: 95.23

GC content: 53.28

Gene sequence:

>732_bases
ATTATCATTAATGCGACTCCAGAAAAGAGCCGAATCGGCAATATTGCTGTGTTTTTAGTGGGGATACGATTTCCCTGTAT
TAACTATTATCTTTATCTTTCAGCCGTCAAGGCGGGCGTCCACTTTTTTAGCGCAGAGGGAGAAACAGCTATGCAGCGTT
GCGGATGGGTGAGTCAGGATCCGTTATACATCGAGTATCACGATACCGAATGGGGTGTGGCGCAAAAAGAGGGTCGCCAG
CTGTTTGAAATGATCTGCCTTGAGGGCCAGCAGGCCGGTTTATCGTGGATTACGGTGTTAAAAAAACGGCAGAACTACCG
CCAGGCTTTTCACCAGTTCGATCCGGTGCGCGTGGCGGCGATGGGTGATGACGATATCGAGCGACTCCTGCAGGATACCG
GCATCATTCGCCATCGGGGAAAAATCCAGGCCATTATCGGCAACGCCCGCGCCTATCTGGCGATGGAAGAAAATGGCGAG
TCGTTCACTGATTTTGTCTGGTCCTTCGTCGACAATGCGCCACAGGTGACCCGCGCTGCGACGCTGGCGGAAATTCCCGC
CACGACGCCGGCCTCCGATGCGCTGTCGAAGGCATTGAAAAAACGCGGCTTTAAGTTTGTCGGCTCGACAATCTGTTATT
CCTTTATGCAGGCCTGTGGGCTGGTCAACGACCATGTCACCGGCTGCTTCTGTCACCCTGGAGGTCAGGATGATCCGCAA
GTGGGACACTGA

Upstream 100 bases:

>100_bases
GATATATTCCTGTTGCCAGGCATTCGCTCCAGAGACACATGACACCCAGACGGATACGCTCGCCGGGATCAAGAACCCCC
GGAGGCCATTGCATTTCTTT

Downstream 100 bases:

>100_bases
AGATACCGCGCCGCTGCTGGCGCTGTGGCTGGACAGCACGATTCATGCCCATCCTTTTATCAGCGAAAGCTACTGGCGCG
ACAGCGTCGCGGTAGTACGG

Product: 3-methyl-adenine DNA glycosylase I

Products: NA

Alternate protein names: 3-methyladenine-DNA glycosylase I, constitutive; TAG I; DNA-3-methyladenine glycosidase I; DNA-3-methyladenine glycosylase I [H]

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MIINATPEKSRIGNIAVFLVGIRFPCINYYLYLSAVKAGVHFFSAEGETAMQRCGWVSQDPLYIEYHDTEWGVAQKEGRQ
LFEMICLEGQQAGLSWITVLKKRQNYRQAFHQFDPVRVAAMGDDDIERLLQDTGIIRHRGKIQAIIGNARAYLAMEENGE
SFTDFVWSFVDNAPQVTRAATLAEIPATTPASDALSKALKKRGFKFVGSTICYSFMQACGLVNDHVTGCFCHPGGQDDPQ
VGH

Sequences:

>Translated_243_residues
MIINATPEKSRIGNIAVFLVGIRFPCINYYLYLSAVKAGVHFFSAEGETAMQRCGWVSQDPLYIEYHDTEWGVAQKEGRQ
LFEMICLEGQQAGLSWITVLKKRQNYRQAFHQFDPVRVAAMGDDDIERLLQDTGIIRHRGKIQAIIGNARAYLAMEENGE
SFTDFVWSFVDNAPQVTRAATLAEIPATTPASDALSKALKKRGFKFVGSTICYSFMQACGLVNDHVTGCFCHPGGQDDPQ
VGH
>Mature_243_residues
MIINATPEKSRIGNIAVFLVGIRFPCINYYLYLSAVKAGVHFFSAEGETAMQRCGWVSQDPLYIEYHDTEWGVAQKEGRQ
LFEMICLEGQQAGLSWITVLKKRQNYRQAFHQFDPVRVAAMGDDDIERLLQDTGIIRHRGKIQAIIGNARAYLAMEENGE
SFTDFVWSFVDNAPQVTRAATLAEIPATTPASDALSKALKKRGFKFVGSTICYSFMQACGLVNDHVTGCFCHPGGQDDPQ
VGH

Specific function: Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine from the damaged DNA polymer formed by alkylation lesions [H]

COG id: COG2818

COG function: function code L; 3-methyladenine DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789971, Length=186, Percent_Identity=79.0322580645161, Blast_Score=326, Evalue=1e-90,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005019
- InterPro:   IPR011257
- InterPro:   IPR004597 [H]

Pfam domain/function: PF03352 Adenine_glyco [H]

EC number: =3.2.2.20 [H]

Molecular weight: Translated: 27076; Mature: 27076

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIINATPEKSRIGNIAVFLVGIRFPCINYYLYLSAVKAGVHFFSAEGETAMQRCGWVSQD
CEECCCCCCHHHCCEEEEEEHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHCCCCCCC
PLYIEYHDTEWGVAQKEGRQLFEMICLEGQQAGLSWITVLKKRQNYRQAFHQFDPVRVAA
CEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEE
MGDDDIERLLQDTGIIRHRGKIQAIIGNARAYLAMEENGESFTDFVWSFVDNAPQVTRAA
CCCHHHHHHHHHCCHHHCCCCEEEEEECCEEEEEECCCCCHHHHHHHHHHCCCCHHHHHH
TLAEIPATTPASDALSKALKKRGFKFVGSTICYSFMQACGLVNDHVTGCFCHPGGQDDPQ
HHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCC
VGH
CCC
>Mature Secondary Structure
MIINATPEKSRIGNIAVFLVGIRFPCINYYLYLSAVKAGVHFFSAEGETAMQRCGWVSQD
CEECCCCCCHHHCCEEEEEEHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHCCCCCCC
PLYIEYHDTEWGVAQKEGRQLFEMICLEGQQAGLSWITVLKKRQNYRQAFHQFDPVRVAA
CEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEE
MGDDDIERLLQDTGIIRHRGKIQAIIGNARAYLAMEENGESFTDFVWSFVDNAPQVTRAA
CCCHHHHHHHHHCCHHHCCCCEEEEEECCEEEEEECCCCCHHHHHHHHHHCCCCHHHHHH
TLAEIPATTPASDALSKALKKRGFKFVGSTICYSFMQACGLVNDHVTGCFCHPGGQDDPQ
HHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCC
VGH
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3536912; 3520491; 8041620; 9278503 [H]