BacMap

Definition	Klebsiella pneumoniae NTUH-K2044 chromosome, complete genome.
Accession	NC_012731
Length	5,248,520

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The map label for this gene is fabG [H]

Identifier: 238896969

GI number: 238896969

Start: 4945179

End: 4946075

Strand: Reverse

Name: fabG [H]

Synonym: KP1_5211

Alternate gene names: 238896969

Gene position: 4946075-4945179 (Counterclockwise)

Preceding gene: 238896973

Following gene: 238896965

Centisome position: 94.24

GC content: 57.41

Gene sequence:

>897_bases
TTGCATGAATTTTATCCATGCCGATCGCCTATTGTTGTTGTTACTGAAACAGTAAAACGCAATATAGCGTATTTATTGTT
GCATGAGCAGTTAATAAGCTACAACACAATCACAACGCAACCTGAAAGGGGTCTTCTGATGACACAACGTATCGCTTTAG
TGACCGGCGGCAGCCGCGGTCTGGGTAAAAACGCCGCGTTGAAGCTGGCGGCAAAGGGAACCGATATTCTTTTGACCTAT
CACAGCAACCGCCAGGCGGCCCTCGACGTGGTGGCGGAAATAGAGCAAAAAGGGGTCAAAGCGGCAGCATTAGCGCTGAA
CGTCGGCGATTCCACAACATTTGACTCATTCGCCAGCGAGGTGGCGCAGGTGCTGGCGCAGAAGTGGGGACGCACAACCT
TTGATTATTTACTGAACAATGCCGGGATCGGACTCAACGCGCCCTTCGCCGAGACCAGCGAAGCGCAGTTTGACGAGCTG
ATGAATATCCAGTTCAAAGGGCCGTTTTTCCTGACCCAGCGTCTGCTGCCTCTCCTGCAGGATGGGGGGCGTATCCTTAA
TGTCTCCAGCGGCCTGGCGCGCTTTGCCCTGCCGGGCTATGCGGCCTACGCCGCGATGAAGGGGGCGATGGAGGTTCTGA
CCCGCTATCAGGCGAAAGAGCTGGGCGGACGGGGGATATCGGTGAACATCATCGCGCCGGGGGCCATTGAGACTGACTTT
GGCGGCGGGGAGGTGCGCGATAACGCCGAGGTGAATCGGCATATCGCCGCCCAGACTGCGCTGGGGCGCGTTGGGCTGCC
GGATGATATCGGCGACGCCATCGCCGCCCTGCTCAGCGATGAGCTGGCGTGGATGAACGCGCAGCGTGTGGAAGTCTCGG
GTGGGATGTTCCTCTGA

Upstream 100 bases:

>100_bases
AGGGCCTGAATCTGTCGCGAGACGCTACCCTTAGGTAGCGCCAGGGTCTCGGCGGCGCGGGAGAAGCTCTCCAGATCCGC
TACGCGAATGAATAACTGCA

Downstream 100 bases:

>100_bases
TCCTGACTGCCCCCAGCCTGTGACCGGCGGTGCGCTACGGCGCATCGCCCTCCCCACGCAGCCGACCGAACAGCCAGTCG
TTGTGCCAGCGTCCGTTGAG

Product: oxidoreductase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MHEFYPCRSPIVVVTETVKRNIAYLLLHEQLISYNTITTQPERGLLMTQRIALVTGGSRGLGKNAALKLAAKGTDILLTY
HSNRQAALDVVAEIEQKGVKAAALALNVGDSTTFDSFASEVAQVLAQKWGRTTFDYLLNNAGIGLNAPFAETSEAQFDEL
MNIQFKGPFFLTQRLLPLLQDGGRILNVSSGLARFALPGYAAYAAMKGAMEVLTRYQAKELGGRGISVNIIAPGAIETDF
GGGEVRDNAEVNRHIAAQTALGRVGLPDDIGDAIAALLSDELAWMNAQRVEVSGGMFL

Sequences:

>Translated_298_residues
MHEFYPCRSPIVVVTETVKRNIAYLLLHEQLISYNTITTQPERGLLMTQRIALVTGGSRGLGKNAALKLAAKGTDILLTY
HSNRQAALDVVAEIEQKGVKAAALALNVGDSTTFDSFASEVAQVLAQKWGRTTFDYLLNNAGIGLNAPFAETSEAQFDEL
MNIQFKGPFFLTQRLLPLLQDGGRILNVSSGLARFALPGYAAYAAMKGAMEVLTRYQAKELGGRGISVNIIAPGAIETDF
GGGEVRDNAEVNRHIAAQTALGRVGLPDDIGDAIAALLSDELAWMNAQRVEVSGGMFL
>Mature_298_residues
MHEFYPCRSPIVVVTETVKRNIAYLLLHEQLISYNTITTQPERGLLMTQRIALVTGGSRGLGKNAALKLAAKGTDILLTY
HSNRQAALDVVAEIEQKGVKAAALALNVGDSTTFDSFASEVAQVLAQKWGRTTFDYLLNNAGIGLNAPFAETSEAQFDEL
MNIQFKGPFFLTQRLLPLLQDGGRILNVSSGLARFALPGYAAYAAMKGAMEVLTRYQAKELGGRGISVNIIAPGAIETDF
GGGEVRDNAEVNRHIAAQTALGRVGLPDDIGDAIAALLSDELAWMNAQRVEVSGGMFL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI5031737, Length=266, Percent_Identity=27.8195488721804, Blast_Score=95, Evalue=7e-20,
Organism=Homo sapiens, GI32483357, Length=256, Percent_Identity=28.125, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI15277342, Length=257, Percent_Identity=29.1828793774319, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI7705925, Length=256, Percent_Identity=27.734375, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI33667109, Length=212, Percent_Identity=30.188679245283, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI40254992, Length=257, Percent_Identity=28.7937743190661, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI4503817, Length=226, Percent_Identity=26.1061946902655, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI126723750, Length=255, Percent_Identity=24.7058823529412, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI119392083, Length=205, Percent_Identity=32.6829268292683, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI20149619, Length=263, Percent_Identity=25.0950570342205, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI1788459, Length=252, Percent_Identity=32.1428571428571, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1787335, Length=254, Percent_Identity=32.2834645669291, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI2367175, Length=254, Percent_Identity=33.4645669291339, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1789378, Length=256, Percent_Identity=32.421875, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1790717, Length=248, Percent_Identity=27.8225806451613, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1787905, Length=253, Percent_Identity=32.8063241106719, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI2367365, Length=251, Percent_Identity=28.2868525896414, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI87082100, Length=267, Percent_Identity=29.9625468164794, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1789208, Length=249, Percent_Identity=29.3172690763052, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1786701, Length=230, Percent_Identity=32.1739130434783, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI87082160, Length=251, Percent_Identity=27.0916334661355, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1787526, Length=203, Percent_Identity=32.0197044334975, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786812, Length=255, Percent_Identity=27.4509803921569, Blast_Score=69, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17560676, Length=263, Percent_Identity=29.277566539924, Blast_Score=105, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI71994600, Length=249, Percent_Identity=29.718875502008, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17561402, Length=258, Percent_Identity=30.2325581395349, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71994604, Length=257, Percent_Identity=30.3501945525292, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17562906, Length=265, Percent_Identity=30.9433962264151, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI115534694, Length=254, Percent_Identity=27.9527559055118, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17562910, Length=267, Percent_Identity=28.8389513108614, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17559104, Length=266, Percent_Identity=28.5714285714286, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17562908, Length=263, Percent_Identity=30.7984790874525, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17544670, Length=275, Percent_Identity=28.3636363636364, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI193204405, Length=204, Percent_Identity=32.843137254902, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI25147288, Length=263, Percent_Identity=27.7566539923954, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17555706, Length=261, Percent_Identity=25.2873563218391, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17562904, Length=200, Percent_Identity=30.5, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17560150, Length=258, Percent_Identity=29.0697674418605, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17536025, Length=260, Percent_Identity=26.1538461538462, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17568967, Length=198, Percent_Identity=30.3030303030303, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17565030, Length=273, Percent_Identity=29.6703296703297, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71982365, Length=195, Percent_Identity=31.2820512820513, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17562990, Length=257, Percent_Identity=28.7937743190661, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17551412, Length=278, Percent_Identity=27.6978417266187, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17531453, Length=195, Percent_Identity=32.3076923076923, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17561272, Length=239, Percent_Identity=26.7782426778243, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17536651, Length=256, Percent_Identity=25, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17538486, Length=270, Percent_Identity=26.6666666666667, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17560220, Length=198, Percent_Identity=30.3030303030303, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17558990, Length=220, Percent_Identity=28.6363636363636, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17538480, Length=269, Percent_Identity=26.7657992565056, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17560332, Length=268, Percent_Identity=27.9850746268657, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=200, Percent_Identity=29.5, Blast_Score=74, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6323882, Length=235, Percent_Identity=27.6595744680851, Blast_Score=68, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6324126, Length=270, Percent_Identity=25.9259259259259, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24643142, Length=246, Percent_Identity=30.0813008130081, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI28571526, Length=250, Percent_Identity=33.2, Blast_Score=101, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24639444, Length=255, Percent_Identity=30.5882352941176, Blast_Score=100, Evalue=8e-22,
Organism=Drosophila melanogaster, GI24644339, Length=250, Percent_Identity=32, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI21357041, Length=250, Percent_Identity=33.6, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI23397609, Length=256, Percent_Identity=28.515625, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21355319, Length=256, Percent_Identity=27.34375, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24644337, Length=166, Percent_Identity=36.144578313253, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21358495, Length=197, Percent_Identity=27.9187817258883, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24647946, Length=208, Percent_Identity=29.3269230769231, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI45553409, Length=208, Percent_Identity=29.3269230769231, Blast_Score=68, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24647948, Length=208, Percent_Identity=29.3269230769231, Blast_Score=68, Evalue=8e-12,
Organism=Drosophila melanogaster, GI18859837, Length=196, Percent_Identity=31.1224489795918, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21356301, Length=217, Percent_Identity=27.1889400921659, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 32029; Mature: 32029

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHEFYPCRSPIVVVTETVKRNIAYLLLHEQLISYNTITTQPERGLLMTQRIALVTGGSRG
CCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEEECCCCC
LGKNAALKLAAKGTDILLTYHSNRQAALDVVAEIEQKGVKAAALALNVGDSTTFDSFASE
CCCCCEEEEEECCCEEEEEEECCCHHHHHHHHHHHHCCCEEEEEEEECCCCCCHHHHHHH
VAQVLAQKWGRTTFDYLLNNAGIGLNAPFAETSEAQFDELMNIQFKGPFFLTQRLLPLLQ
HHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHEEEECCCHHHHHHHHHHHH
DGGRILNVSSGLARFALPGYAAYAAMKGAMEVLTRYQAKELGGRGISVNIIAPGAIETDF
CCCEEEEECCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCEECCC
GGGEVRDNAEVNRHIAAQTALGRVGLPDDIGDAIAALLSDELAWMNAQRVEVSGGMFL
CCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCC
>Mature Secondary Structure
MHEFYPCRSPIVVVTETVKRNIAYLLLHEQLISYNTITTQPERGLLMTQRIALVTGGSRG
CCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEEECCCCC
LGKNAALKLAAKGTDILLTYHSNRQAALDVVAEIEQKGVKAAALALNVGDSTTFDSFASE
CCCCCEEEEEECCCEEEEEEECCCHHHHHHHHHHHHCCCEEEEEEEECCCCCCHHHHHHH
VAQVLAQKWGRTTFDYLLNNAGIGLNAPFAETSEAQFDELMNIQFKGPFFLTQRLLPLLQ
HHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHEEEECCCHHHHHHHHHHHH
DGGRILNVSSGLARFALPGYAAYAAMKGAMEVLTRYQAKELGGRGISVNIIAPGAIETDF
CCCEEEEECCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCEECCC
GGGEVRDNAEVNRHIAAQTALGRVGLPDDIGDAIAALLSDELAWMNAQRVEVSGGMFL
CCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9384377; 9534248; 8654983 [H]