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The map label for this gene is glpD [H]

Identifier: 238896889

GI number: 238896889

Start: 4858985

End: 4860493

Strand: Direct

Name: glpD [H]

Synonym: KP1_5126

Alternate gene names: 238896889

Gene position: 4858985-4860493 (Clockwise)

Preceding gene: 238896885

Following gene: 238896896

Centisome position: 92.58

GC content: 58.45

Gene sequence:

>1509_bases
GTGGAAACCAAAGATCTGATTGTGATAGGCGGAGGCATCAACGGTGCCGGTATCGCGGCAGATGCCGCCGGGCGTGGTTT
ATCCGTACTGATGCTGGAAGCGCGCGATCTCGCCTGCGCCACCTCCAGCGCCAGTTCCAAACTGATCCACGGCGGGCTAC
GCTACCTCGAACACTATGAGTTCCGTCTGGTCAGCGAAGCGCTGGCCGAGCGTGAGGTGCTGTTAAAAATGGCCCCGCAT
ATCGCCTTCCCGATGCGCTTTCGCCTACCGCATCGCCCGCATCTGCGCCCGGCATGGATGATCCGTATCGGCTTGTTTAT
GTACGATCATCTGGGCAAACGCACCAGCCTCCCGGGATCCACCGGGTTGCGTTTTGGCGCAGAATCGGTACTTAAACCGG
AAATTGTGCGCGGTTTCGAATATTCCGACTGCTGGGTCGACGATGCCCGCCTGGTGCTGGCCAACGCGCAGATGGTCGTC
CGCAAAGGCGGCGAAGTGCGTACCCGCACCCGCGCTATCTCAGCGAAACGTGAGAATGGCCTGTGGGTGGTGGAAGCGGA
AGATATTGATAGCGGTGAGAAGTTTACCTGGAAGGCGCGCGGCCTGGTCAATGCCACCGGCCCATGGGTCAAACAGTTCT
TCGACGAAGGGATGCATCTGCGCTCGCCTTACGGCATCCGTCTGATCAAGGGCAGCCACATCGTGGTGCCGCGGGTGCAT
ACCCAGAAACAGGCTTATATTCTGCAGAACGAAGATAAACGCATAGTGTTTGTTATTCCGTGGATGGATGAGTTCTCTAT
CATCGGCACGACGGACGTCGAGTATAAGGGCGATCCGAAAGCGGTGGCCATTGATGATAAAGAGATCAACTATCTGCTGA
ACGTCTATAACGCGCACTTTAAAAAGACCCTCAGCCGGGACGATATCGTCTGGACCTACTCCGGCGTCCGTCCGCTGTGC
GACGACGAGTCGGATTCGCCGCAGGCCATTACCCGCGACTATACCCTGGATATTCACGATGAGAACGGTCAGGCGCCGCT
GCTGTCCGTCTTCGGCGGCAAGCTGACCACCTATCGCAAACTGGCCGAGCATGCACTGGAAAAACTGACCCCCTATTACA
AAGGGATCGGCCCGGCATGGACCAAAACCGCTGTGCTCCCCGGCGGCGATATCGGCGGCGACCGCGACGACTACGCGGCA
AAACTGCGCCGTCGCTTCCCGTTCATCAGTGAATCACTGGCCCGCCATTATGCCCGCACCTACGGGAGCAACAGCGAGTG
GATCCTGAAGGAAGCCAGCGCCCTGAGCGATCTCGGGGAAGATTTCGGCCACGAGTTTTATGAAGCCGAGCTGAAATATC
TGGTGGAGCACGAGTGGGTGCGCAGCCTGGATGACGCCATCTGGCGTCGAACCAAACAGGGTATGTGGCTGACTGCCGAG
CAGCAGGCGCGCATCAGCGAATGGCTGGCGCAGCATGCGGGAAAGTCTGAACTGTCGTTAGCGTCGTAA

Upstream 100 bases:

>100_bases
TCAAAATGTTTTTTTGATGTTACCAAAAGCGCGTTTGTTTGCTATAGTGAGCGATATCGAGCATTTATGAGCTTAAACGA
AAGTGTGAGAGGGTAAGAAC

Downstream 100 bases:

>100_bases
CGCTGCCCGGCGGAAACGCCTGAGGCCAGGTTCAACCGCAATAATCAAACAACGGGGCCAAATGGCCCCGTTGTGTTGCG
TTGACTGGCTTACAGCCTTA

Product: glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 502; Mature: 502

Protein sequence:

>502_residues
METKDLIVIGGGINGAGIAADAAGRGLSVLMLEARDLACATSSASSKLIHGGLRYLEHYEFRLVSEALAEREVLLKMAPH
IAFPMRFRLPHRPHLRPAWMIRIGLFMYDHLGKRTSLPGSTGLRFGAESVLKPEIVRGFEYSDCWVDDARLVLANAQMVV
RKGGEVRTRTRAISAKRENGLWVVEAEDIDSGEKFTWKARGLVNATGPWVKQFFDEGMHLRSPYGIRLIKGSHIVVPRVH
TQKQAYILQNEDKRIVFVIPWMDEFSIIGTTDVEYKGDPKAVAIDDKEINYLLNVYNAHFKKTLSRDDIVWTYSGVRPLC
DDESDSPQAITRDYTLDIHDENGQAPLLSVFGGKLTTYRKLAEHALEKLTPYYKGIGPAWTKTAVLPGGDIGGDRDDYAA
KLRRRFPFISESLARHYARTYGSNSEWILKEASALSDLGEDFGHEFYEAELKYLVEHEWVRSLDDAIWRRTKQGMWLTAE
QQARISEWLAQHAGKSELSLAS

Sequences:

>Translated_502_residues
METKDLIVIGGGINGAGIAADAAGRGLSVLMLEARDLACATSSASSKLIHGGLRYLEHYEFRLVSEALAEREVLLKMAPH
IAFPMRFRLPHRPHLRPAWMIRIGLFMYDHLGKRTSLPGSTGLRFGAESVLKPEIVRGFEYSDCWVDDARLVLANAQMVV
RKGGEVRTRTRAISAKRENGLWVVEAEDIDSGEKFTWKARGLVNATGPWVKQFFDEGMHLRSPYGIRLIKGSHIVVPRVH
TQKQAYILQNEDKRIVFVIPWMDEFSIIGTTDVEYKGDPKAVAIDDKEINYLLNVYNAHFKKTLSRDDIVWTYSGVRPLC
DDESDSPQAITRDYTLDIHDENGQAPLLSVFGGKLTTYRKLAEHALEKLTPYYKGIGPAWTKTAVLPGGDIGGDRDDYAA
KLRRRFPFISESLARHYARTYGSNSEWILKEASALSDLGEDFGHEFYEAELKYLVEHEWVRSLDDAIWRRTKQGMWLTAE
QQARISEWLAQHAGKSELSLAS
>Mature_502_residues
METKDLIVIGGGINGAGIAADAAGRGLSVLMLEARDLACATSSASSKLIHGGLRYLEHYEFRLVSEALAEREVLLKMAPH
IAFPMRFRLPHRPHLRPAWMIRIGLFMYDHLGKRTSLPGSTGLRFGAESVLKPEIVRGFEYSDCWVDDARLVLANAQMVV
RKGGEVRTRTRAISAKRENGLWVVEAEDIDSGEKFTWKARGLVNATGPWVKQFFDEGMHLRSPYGIRLIKGSHIVVPRVH
TQKQAYILQNEDKRIVFVIPWMDEFSIIGTTDVEYKGDPKAVAIDDKEINYLLNVYNAHFKKTLSRDDIVWTYSGVRPLC
DDESDSPQAITRDYTLDIHDENGQAPLLSVFGGKLTTYRKLAEHALEKLTPYYKGIGPAWTKTAVLPGGDIGGDRDDYAA
KLRRRFPFISESLARHYARTYGSNSEWILKEASALSDLGEDFGHEFYEAELKYLVEHEWVRSLDDAIWRRTKQGMWLTAE
QQARISEWLAQHAGKSELSLAS

Specific function: Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses molecular oxygen or nitrate as electron acceptor [H]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=508, Percent_Identity=30.511811023622, Blast_Score=181, Evalue=1e-45,
Organism=Homo sapiens, GI285002231, Length=508, Percent_Identity=30.511811023622, Blast_Score=181, Evalue=1e-45,
Organism=Escherichia coli, GI2367226, Length=502, Percent_Identity=89.2430278884462, Blast_Score=895, Evalue=0.0,
Organism=Escherichia coli, GI1788574, Length=472, Percent_Identity=26.6949152542373, Blast_Score=90, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI115534726, Length=516, Percent_Identity=30.8139534883721, Blast_Score=160, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI17509253, Length=521, Percent_Identity=28.5988483685221, Blast_Score=150, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6322036, Length=531, Percent_Identity=27.1186440677966, Blast_Score=153, Evalue=7e-38,
Organism=Drosophila melanogaster, GI161077125, Length=533, Percent_Identity=30.3939962476548, Blast_Score=164, Evalue=1e-40,
Organism=Drosophila melanogaster, GI24653942, Length=533, Percent_Identity=30.3939962476548, Blast_Score=164, Evalue=1e-40,
Organism=Drosophila melanogaster, GI24653944, Length=533, Percent_Identity=30.3939962476548, Blast_Score=164, Evalue=1e-40,
Organism=Drosophila melanogaster, GI20130025, Length=533, Percent_Identity=30.3939962476548, Blast_Score=164, Evalue=1e-40,
Organism=Drosophila melanogaster, GI24586295, Length=501, Percent_Identity=25.748502994012, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI19921278, Length=496, Percent_Identity=25.2016129032258, Blast_Score=99, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 56669; Mature: 56669

Theoretical pI: Translated: 7.29; Mature: 7.29

Prosite motif: PS00977 FAD_G3PDH_1 ; PS00978 FAD_G3PDH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METKDLIVIGGGINGAGIAADAAGRGLSVLMLEARDLACATSSASSKLIHGGLRYLEHYE
CCCCCEEEECCCCCCCCEECCCCCCCEEEEEEECCCCEEECCCCCHHHHHHHHHHHHHHH
FRLVSEALAEREVLLKMAPHIAFPMRFRLPHRPHLRPAWMIRIGLFMYDHLGKRTSLPGS
HHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCC
TGLRFGAESVLKPEIVRGFEYSDCWVDDARLVLANAQMVVRKGGEVRTRTRAISAKRENG
CCCCCCHHHHCCHHHHCCCCCCCCEECCCEEEEECCCEEECCCCCHHHHHHHHHCCCCCC
LWVVEAEDIDSGEKFTWKARGLVNATGPWVKQFFDEGMHLRSPYGIRLIKGSHIVVPRVH
EEEEECCCCCCCCEEEEEECCCCCCCCHHHHHHHHCCCEECCCCCEEEEECCEEEEECCC
TQKQAYILQNEDKRIVFVIPWMDEFSIIGTTDVEYKGDPKAVAIDDKEINYLLNVYNAHF
CCCEEEEEECCCCEEEEEEECCCCCEEEECCCCCCCCCCCEEEECCHHHHHHHHHHHHHH
KKTLSRDDIVWTYSGVRPLCDDESDSPQAITRDYTLDIHDENGQAPLLSVFGGKLTTYRK
HHHCCCCCEEEEECCCCCCCCCCCCCCCEEEEEEEEEEECCCCCCCCHHHCCCCHHHHHH
LAEHALEKLTPYYKGIGPAWTKTAVLPGGDIGGDRDDYAAKLRRRFPFISESLARHYART
HHHHHHHHHCHHHHCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHH
YGSNSEWILKEASALSDLGEDFGHEFYEAELKYLVEHEWVRSLDDAIWRRTKQGMWLTAE
CCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHH
QQARISEWLAQHAGKSELSLAS
HHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
METKDLIVIGGGINGAGIAADAAGRGLSVLMLEARDLACATSSASSKLIHGGLRYLEHYE
CCCCCEEEECCCCCCCCEECCCCCCCEEEEEEECCCCEEECCCCCHHHHHHHHHHHHHHH
FRLVSEALAEREVLLKMAPHIAFPMRFRLPHRPHLRPAWMIRIGLFMYDHLGKRTSLPGS
HHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCC
TGLRFGAESVLKPEIVRGFEYSDCWVDDARLVLANAQMVVRKGGEVRTRTRAISAKRENG
CCCCCCHHHHCCHHHHCCCCCCCCEECCCEEEEECCCEEECCCCCHHHHHHHHHCCCCCC
LWVVEAEDIDSGEKFTWKARGLVNATGPWVKQFFDEGMHLRSPYGIRLIKGSHIVVPRVH
EEEEECCCCCCCCEEEEEECCCCCCCCHHHHHHHHCCCEECCCCCEEEEECCEEEEECCC
TQKQAYILQNEDKRIVFVIPWMDEFSIIGTTDVEYKGDPKAVAIDDKEINYLLNVYNAHF
CCCEEEEEECCCCEEEEEEECCCCCEEEECCCCCCCCCCCEEEECCHHHHHHHHHHHHHH
KKTLSRDDIVWTYSGVRPLCDDESDSPQAITRDYTLDIHDENGQAPLLSVFGGKLTTYRK
HHHCCCCCEEEEECCCCCCCCCCCCCCCEEEEEEEEEEECCCCCCCCHHHCCCCHHHHHH
LAEHALEKLTPYYKGIGPAWTKTAVLPGGDIGGDRDDYAAKLRRRFPFISESLARHYART
HHHHHHHHHCHHHHCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHH
YGSNSEWILKEASALSDLGEDFGHEFYEAELKYLVEHEWVRSLDDAIWRRTKQGMWLTAE
CCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHH
QQARISEWLAQHAGKSELSLAS
HHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1987111; 9278503; 3045087; 3045764 [H]