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The map label for this gene is hofQ [H]

Identifier: 238896859

GI number: 238896859

Start: 4822991

End: 4824235

Strand: Reverse

Name: hofQ [H]

Synonym: KP1_5092

Alternate gene names: 238896859

Gene position: 4824235-4822991 (Counterclockwise)

Preceding gene: 238896860

Following gene: 238896858

Centisome position: 91.92

GC content: 60.8

Gene sequence:

>1245_bases
ATGATGCGATGGATAAGCCTGCTGCTTCTGCTGCTGCCGCTGGTGGTGGCCCCCGCCGCCCGCAATGATAAACCGGTTTC
GCTGGTGATTGACGATGCGCCAGTGGCTCAGGTGCTGCAAGCCCTGGCCGAAATGAACCATAAGAACCTCGTCGTCGCGC
CGGACGTCAGCGGCACGCTCTCCCTGCGTCTGCAGAAGGTTCCCTGGAGCCAGGCGCTGCGGGCGGTAGCGGATAGCGCG
GGTCTCTCTTTGCAACAGCAGGGGACGGTCATCTACGCGCACACTCAGGCCTGGCAAAAGGCAAATCAGGCGCAGCGTGA
AGCCGAACAGGAGAAACGCCTGCAGAACCTGCCCCTGCAGGCGGAGAGCGTGACCCTGCACTTTGCCGACGCTGAAGAGC
TGGCTAAAAGCGGCGGAAAGCTGCTCAGCGCCAGGGGACACCTGATGGCGGACAAGCGGACTAATCGGCTGCTGATCCGC
GATGATGCCCGGCACCTGCCGGCGTTGAAGGCCTGGGCGCAGGAGATGGATCTGCCGGTCGGCCAGGTGGAGCTGGCCGC
CCATATCGTGTCGATGAGCGAAACCAGCCTTCGTGAGCTGGGGGTGAAGTGGCGGCTTGCGGAAGCCGGAAGCCCGCCAG
GCTCCGGGCAAATCACCACCCTAAGCAGCGATGTATCGGTAAACGATGCCAGCACCCGCGCAGGGTTTAACATCGGCAAG
ATCAACGGTCGCTTGCTTGAGCTGGAGCTATCCGCGCTGGAGCGCAAGCAGCAGGTCGAAATTATTGCCAGCCCGCGTTT
ATTGGCCTCCCACATGCAGCCTGCCAGCATCAAGCAGGGAAGCGAGATCCCCTATCAGGTTTCCAGTGGCGAAAGCGGCG
CCACTTCGGTGGAGTTCAAAGAGGCGGTGCTGGGCATGGAGGTCACGCCGACGGTGCTGCAGCAGGGAAGAGTGCGGCTT
AAGCTGCGAATAAGCGAGAATACGCCAGGCCAGGTGCTGAAGCAGGAAAACGGCGAAGCGCTGGCCATCGATAAGCAGGA
GATAGAGACCCTGGTGGAAGTTCGCAGCGGCGAGACTTTAGCGTTGGGCGGCATCTTTTCGCAGAAAAACAAAACCGCCC
GCGACAGCGTCCCGCTGCTTGGCGATATCCCGGTACTGGGACGTCTGTTTCGTCGTGACGGGAAAGATAATGAACGTCGC
GAACTGGTTGTCTTTATTACGCCACGGATTCTGGCAGTACGTTAA

Upstream 100 bases:

>100_bases
GGCTGGCGGGTGAGCCGGCTGACGGCCGGTGAGCTGGACATCGTCACGTCTTCGGGATGTGAACCGCCAGCGTGGCGCTG
GCAACGTGAAGGGAAACAAC

Downstream 100 bases:

>100_bases
GCAGGTTTTTCATGCTAAACACGTTTCAGGTGTTTGACGTGAGGACGGATTTAGCATACAAGGGGTACCGATTTGAGAGT
CGGGTACGACATCAATCCTC

Product: outer membrane porin HofQ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 414; Mature: 414

Protein sequence:

>414_residues
MMRWISLLLLLLPLVVAPAARNDKPVSLVIDDAPVAQVLQALAEMNHKNLVVAPDVSGTLSLRLQKVPWSQALRAVADSA
GLSLQQQGTVIYAHTQAWQKANQAQREAEQEKRLQNLPLQAESVTLHFADAEELAKSGGKLLSARGHLMADKRTNRLLIR
DDARHLPALKAWAQEMDLPVGQVELAAHIVSMSETSLRELGVKWRLAEAGSPPGSGQITTLSSDVSVNDASTRAGFNIGK
INGRLLELELSALERKQQVEIIASPRLLASHMQPASIKQGSEIPYQVSSGESGATSVEFKEAVLGMEVTPTVLQQGRVRL
KLRISENTPGQVLKQENGEALAIDKQEIETLVEVRSGETLALGGIFSQKNKTARDSVPLLGDIPVLGRLFRRDGKDNERR
ELVVFITPRILAVR

Sequences:

>Translated_414_residues
MMRWISLLLLLLPLVVAPAARNDKPVSLVIDDAPVAQVLQALAEMNHKNLVVAPDVSGTLSLRLQKVPWSQALRAVADSA
GLSLQQQGTVIYAHTQAWQKANQAQREAEQEKRLQNLPLQAESVTLHFADAEELAKSGGKLLSARGHLMADKRTNRLLIR
DDARHLPALKAWAQEMDLPVGQVELAAHIVSMSETSLRELGVKWRLAEAGSPPGSGQITTLSSDVSVNDASTRAGFNIGK
INGRLLELELSALERKQQVEIIASPRLLASHMQPASIKQGSEIPYQVSSGESGATSVEFKEAVLGMEVTPTVLQQGRVRL
KLRISENTPGQVLKQENGEALAIDKQEIETLVEVRSGETLALGGIFSQKNKTARDSVPLLGDIPVLGRLFRRDGKDNERR
ELVVFITPRILAVR
>Mature_414_residues
MMRWISLLLLLLPLVVAPAARNDKPVSLVIDDAPVAQVLQALAEMNHKNLVVAPDVSGTLSLRLQKVPWSQALRAVADSA
GLSLQQQGTVIYAHTQAWQKANQAQREAEQEKRLQNLPLQAESVTLHFADAEELAKSGGKLLSARGHLMADKRTNRLLIR
DDARHLPALKAWAQEMDLPVGQVELAAHIVSMSETSLRELGVKWRLAEAGSPPGSGQITTLSSDVSVNDASTRAGFNIGK
INGRLLELELSALERKQQVEIIASPRLLASHMQPASIKQGSEIPYQVSSGESGATSVEFKEAVLGMEVTPTVLQQGRVRL
KLRISENTPGQVLKQENGEALAIDKQEIETLVEVRSGETLALGGIFSQKNKTARDSVPLLGDIPVLGRLFRRDGKDNERR
ELVVFITPRILAVR

Specific function: Required for the use of extracellular DNA as a nutrient. Could be the porin responsible for transport of DNA across the outer membrane [H]

COG id: COG4796

COG function: function code U; Type II secretory pathway, component HofQ

Gene ontology:

Cell location: Cell outer membrane (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP D family [H]

Homologues:

Organism=Escherichia coli, GI1789793, Length=414, Percent_Identity=68.1159420289855, Blast_Score=561, Evalue=1e-161,
Organism=Escherichia coli, GI87082242, Length=289, Percent_Identity=28.719723183391, Blast_Score=92, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001775
- InterPro:   IPR005644
- InterPro:   IPR013355
- InterPro:   IPR011662
- InterPro:   IPR004846
- InterPro:   IPR004845
- InterPro:   IPR001814 [H]

Pfam domain/function: PF00263 Secretin; PF03958 Secretin_N; PF07660 STN [H]

EC number: NA

Molecular weight: Translated: 45152; Mature: 45152

Theoretical pI: Translated: 9.41; Mature: 9.41

Prosite motif: PS00875 T2SP_D

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMRWISLLLLLLPLVVAPAARNDKPVSLVIDDAPVAQVLQALAEMNHKNLVVAPDVSGTL
CHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCEEEECCCCCEE
SLRLQKVPWSQALRAVADSAGLSLQQQGTVIYAHTQAWQKANQAQREAEQEKRLQNLPLQ
EEEEEECCHHHHHHHHHHHCCCCEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCC
AESVTLHFADAEELAKSGGKLLSARGHLMADKRTNRLLIRDDARHLPALKAWAQEMDLPV
EEEEEEEECCHHHHHHCCCCEEECCCCEEECCCCCEEEEECCCCCCHHHHHHHHHHCCCC
GQVELAAHIVSMSETSLRELGVKWRLAEAGSPPGSGQITTLSSDVSVNDASTRAGFNIGK
CHHHHHHHHHHCCHHHHHHCCCEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCCEEEC
INGRLLELELSALERKQQVEIIASPRLLASHMQPASIKQGSEIPYQVSSGESGATSVEFK
CCCEEEEEEHHHHCCHHHEEEEECCHHHHHCCCCCCCCCCCCCCEEECCCCCCCCCHHHH
EAVLGMEVTPTVLQQGRVRLKLRISENTPGQVLKQENGEALAIDKQEIETLVEVRSGETL
HHHHCCCCCHHHHHCCCEEEEEEECCCCCHHHHHCCCCCEEEECHHHHHHHHHHCCCCEE
ALGGIFSQKNKTARDSVPLLGDIPVLGRLFRRDGKDNERRELVVFITPRILAVR
EEECEECCCCCCCCCCCCCEECCHHHHHHHHCCCCCCCCCEEEEEECCEEEEEC
>Mature Secondary Structure
MMRWISLLLLLLPLVVAPAARNDKPVSLVIDDAPVAQVLQALAEMNHKNLVVAPDVSGTL
CHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCEEEECCCCCEE
SLRLQKVPWSQALRAVADSAGLSLQQQGTVIYAHTQAWQKANQAQREAEQEKRLQNLPLQ
EEEEEECCHHHHHHHHHHHCCCCEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCC
AESVTLHFADAEELAKSGGKLLSARGHLMADKRTNRLLIRDDARHLPALKAWAQEMDLPV
EEEEEEEECCHHHHHHCCCCEEECCCCEEECCCCCEEEEECCCCCCHHHHHHHHHHCCCC
GQVELAAHIVSMSETSLRELGVKWRLAEAGSPPGSGQITTLSSDVSVNDASTRAGFNIGK
CHHHHHHHHHHCCHHHHHHCCCEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCCEEEC
INGRLLELELSALERKQQVEIIASPRLLASHMQPASIKQGSEIPYQVSSGESGATSVEFK
CCCEEEEEEHHHHCCHHHEEEEECCHHHHHCCCCCCCCCCCCCCEEECCCCCCCCCHHHH
EAVLGMEVTPTVLQQGRVRLKLRISENTPGQVLKQENGEALAIDKQEIETLVEVRSGETL
HHHHCCCCCHHHHHCCCEEEEEEECCCCCHHHHHCCCCCEEEECHHHHHHHHHHCCCCEE
ALGGIFSQKNKTARDSVPLLGDIPVLGRLFRRDGKDNERRELVVFITPRILAVR
EEECEECCCCCCCCCCCCCEECCHHHHHHHHCCCCCCCCCEEEEEECCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1309529; 9278503; 7901733 [H]