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The map label for this gene is slyD [H]

Identifier: 238896831

GI number: 238896831

Start: 4794305

End: 4794892

Strand: Reverse

Name: slyD [H]

Synonym: KP1_5061

Alternate gene names: 238896831

Gene position: 4794892-4794305 (Counterclockwise)

Preceding gene: 238896832

Following gene: 238896829

Centisome position: 91.36

GC content: 57.82

Gene sequence:

>588_bases
ATGAAAGTAGCAAAAGACCTGGTGGTCAGCCTGGCCTATCAGGTACGTACAGAAGACGGTGTGTTGGTTGATGAGTCTCC
GGTAAGCGCGCCGCTGGATTACCTGCACGGTCACGGCTCCCTGATTTCCGGCCTGGAAAACGCGCTGGATGGCCACGAAG
TGGGCGACAAATTTGACGTTGCCGTCGGCGCTAACGACGCTTACGGTCAGTATGACGAAAACCTGGTGCAGCGTGTACCA
AAAGACGTCTTCATGGGCGTTGATGAACTGCAGGTTGGCATGCGCTTCCTGGCTGAAACCGATCAGGGTCCGGTACCAGT
AGAAATCACTGAAGTTGAAGACGACCACGTTGTGGTTGATGGCAACCACATGCTGGCTGGCCAGAACCTGAAGTTTAATG
TGGAAGTCGTCGCCATCCGCGAAGCGACTGCGGAAGAGCTGGAGCACGGTCACGTGCACGGCGCGCATGGCCACGATCAC
GATCATGACCATGGTCATGACGGTTGCTGCGGCGGCCACGGCCACGATCATGGTCACGACCATGGTAAAGGCGGCTGCGG
CGGCCACGGTGGCTGCGGCTGCCACTAA

Upstream 100 bases:

>100_bases
CGACTAGCGTTATCCGTCGGCTTTTTTTAAGCTAAAGGGTACACGGCAGCAGAATTCCGCTACAATCTGCGCCACTATTC
TTCCCATCTCAGGAGATATC

Downstream 100 bases:

>100_bases
TCTTTGCGCTTCGGCACGAAGACGACAAAAAAGCGGGGAAACCCGCTTTTTTTACGCCTCAATAGTGCGGCGGTGGCGTC
TCTTCCGCCTGGGAGGCGAT

Product: FKBP-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: PPIase; Metallochaperone slyD [H]

Number of amino acids: Translated: 195; Mature: 195

Protein sequence:

>195_residues
MKVAKDLVVSLAYQVRTEDGVLVDESPVSAPLDYLHGHGSLISGLENALDGHEVGDKFDVAVGANDAYGQYDENLVQRVP
KDVFMGVDELQVGMRFLAETDQGPVPVEITEVEDDHVVVDGNHMLAGQNLKFNVEVVAIREATAEELEHGHVHGAHGHDH
DHDHGHDGCCGGHGHDHGHDHGKGGCGGHGGCGCH

Sequences:

>Translated_195_residues
MKVAKDLVVSLAYQVRTEDGVLVDESPVSAPLDYLHGHGSLISGLENALDGHEVGDKFDVAVGANDAYGQYDENLVQRVP
KDVFMGVDELQVGMRFLAETDQGPVPVEITEVEDDHVVVDGNHMLAGQNLKFNVEVVAIREATAEELEHGHVHGAHGHDH
DHDHGHDGCCGGHGHDHGHDHGKGGCGGHGGCGCH
>Mature_195_residues
MKVAKDLVVSLAYQVRTEDGVLVDESPVSAPLDYLHGHGSLISGLENALDGHEVGDKFDVAVGANDAYGQYDENLVQRVP
KDVFMGVDELQVGMRFLAETDQGPVPVEITEVEDDHVVVDGNHMLAGQNLKFNVEVVAIREATAEELEHGHVHGAHGHDH
DHDHGHDGCCGGHGHDHGHDHGKGGCGGHGGCGCH

Specific function: Also involved in hydrogenase metallocenter assembly, probably by participating in the nickel insertion step. This function in hydrogenase biosynthesis requires chaperone activity and the presence of the metal-binding domain, but not PPIase activity [H]

COG id: COG1047

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 2

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1789748, Length=147, Percent_Identity=97.2789115646258, Blast_Score=285, Evalue=1e-78,
Organism=Escherichia coli, GI1786211, Length=133, Percent_Identity=33.0827067669173, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 20744; Mature: 20744

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVAKDLVVSLAYQVRTEDGVLVDESPVSAPLDYLHGHGSLISGLENALDGHEVGDKFDV
CCHHHHHHHHHHHHEECCCCEEEECCCCCCCHHHHCCCCHHHHHHHHHCCCCCCCCEEEE
AVGANDAYGQYDENLVQRVPKDVFMGVDELQVGMRFLAETDQGPVPVEITEVEDDHVVVD
EECCCCCCCHHHHHHHHHCCHHHHCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEEC
GNHMLAGQNLKFNVEVVAIREATAEELEHGHVHGAHGHDHDHDHGHDGCCGGHGHDHGHD
CCEEEECCCEEEEEEEEEECCHHHHHHHCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCC
HGKGGCGGHGGCGCH
CCCCCCCCCCCCCCC
>Mature Secondary Structure
MKVAKDLVVSLAYQVRTEDGVLVDESPVSAPLDYLHGHGSLISGLENALDGHEVGDKFDV
CCHHHHHHHHHHHHEECCCCEEEECCCCCCCHHHHCCCCHHHHHHHHHCCCCCCCCEEEE
AVGANDAYGQYDENLVQRVPKDVFMGVDELQVGMRFLAETDQGPVPVEITEVEDDHVVVD
EECCCCCCCHHHHHHHHHCCHHHHCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEEC
GNHMLAGQNLKFNVEVVAIREATAEELEHGHVHGAHGHDHDHDHGHDGCCGGHGHDHGHD
CCEEEECCCEEEEEEEEEECCHHHHHHHCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCC
HGKGGCGGHGGCGCH
CCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]