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The map label for this gene is gspO [H]

Identifier: 238896818

GI number: 238896818

Start: 4785119

End: 4785604

Strand: Direct

Name: gspO [H]

Synonym: KP1_5046

Alternate gene names: 238896818

Gene position: 4785119-4785604 (Clockwise)

Preceding gene: 238896787

Following gene: 238896830

Centisome position: 91.17

GC content: 59.05

Gene sequence:

>486_bases
ATGCTCGCCGCCCTCCCCTTCTTGCTGTGCTATAGCGGTTTGACCGTGGCATTATGCCACCAGGATCTGCGCCACGGTCT
GTTGCCCGACCGTTACACCTGTCCCCTGCTGTGGAGTGGTTTACTTTTTTATCTCTGTCTGGCGCCGCACCAGCTGCATG
ATGCCGTCTGGGGGGCGATAGCGGGCTATCTCTCTTTGGCTGCGATTTACTGGCTATACCGCGGTATCCGCGGCTATGAA
GGGTTGGGTTATGGAGATATAAAATATCTTGCCGCCCTCGGCGCCTGGCATGGCTGGCGATTGCTGCCGCAGTTGGTCCT
GGTTGCCTCGCTACTCGCCGGCATAGCGTGGGCAGGAGCAGGTTTATACGCCAGTTGCGGCAGGAAGAGCAAATGGGGAA
GAAGCAACCCGCTGCCGTTTGGGCCATTCCTGGCGGCCGCGGGTTTTTGGTGCGGGTGGCAGACGCTGGCTAGTCTGACA
CTTTGA

Upstream 100 bases:

>100_bases
GCGCGGATTGTGGGATCCATTCCCGGAAAATGCCTTTTGTGCTGAACGGGAGAGGATGAGCATAGTGACGCAATGTTCAT
CGATCATTGCGGGGTCAACT

Downstream 100 bases:

>100_bases
TCTGCGACTGCAGGTAATTTTGCAGACCGATTTTGCCAATCAAATCGAGTTCGGTTTCCAGCCAGTCGATATGGCCTTCT
TCATCCGCCAGGATCTCAAT

Product: bifunctional prepilin leader peptidase and N-methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 161; Mature: 161

Protein sequence:

>161_residues
MLAALPFLLCYSGLTVALCHQDLRHGLLPDRYTCPLLWSGLLFYLCLAPHQLHDAVWGAIAGYLSLAAIYWLYRGIRGYE
GLGYGDIKYLAALGAWHGWRLLPQLVLVASLLAGIAWAGAGLYASCGRKSKWGRSNPLPFGPFLAAAGFWCGWQTLASLT
L

Sequences:

>Translated_161_residues
MLAALPFLLCYSGLTVALCHQDLRHGLLPDRYTCPLLWSGLLFYLCLAPHQLHDAVWGAIAGYLSLAAIYWLYRGIRGYE
GLGYGDIKYLAALGAWHGWRLLPQLVLVASLLAGIAWAGAGLYASCGRKSKWGRSNPLPFGPFLAAAGFWCGWQTLASLT
L
>Mature_161_residues
MLAALPFLLCYSGLTVALCHQDLRHGLLPDRYTCPLLWSGLLFYLCLAPHQLHDAVWGAIAGYLSLAAIYWLYRGIRGYE
GLGYGDIKYLAALGAWHGWRLLPQLVLVASLLAGIAWAGAGLYASCGRKSKWGRSNPLPFGPFLAAAGFWCGWQTLASLT
L

Specific function: Cleaves Type-4 Fimbrial Leader Sequence And Methylates The N-Terminal (Generally Phe) Residue (By Similarity). [C]

COG id: COG1989

COG function: function code NOU; Type II secretory pathway, prepilin signal peptidase PulO and related peptidases

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A24 family [H]

Homologues:

Organism=Escherichia coli, GI1789732, Length=138, Percent_Identity=44.2028985507246, Blast_Score=74, Evalue=3e-15,
Organism=Escherichia coli, GI87082194, Length=129, Percent_Identity=35.6589147286822, Blast_Score=66, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014032
- InterPro:   IPR000045 [H]

Pfam domain/function: PF01478 Peptidase_A24 [H]

EC number: 3.4.23.43

Molecular weight: Translated: 17584; Mature: 17584

Theoretical pI: Translated: 8.78; Mature: 8.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.7 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
3.7 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAALPFLLCYSGLTVALCHQDLRHGLLPDRYTCPLLWSGLLFYLCLAPHQLHDAVWGAI
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHH
AGYLSLAAIYWLYRGIRGYEGLGYGDIKYLAALGAWHGWRLLPQLVLVASLLAGIAWAGA
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GLYASCGRKSKWGRSNPLPFGPFLAAAGFWCGWQTLASLTL
CHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLAALPFLLCYSGLTVALCHQDLRHGLLPDRYTCPLLWSGLLFYLCLAPHQLHDAVWGAI
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHH
AGYLSLAAIYWLYRGIRGYEGLGYGDIKYLAALGAWHGWRLLPQLVLVASLLAGIAWAGA
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GLYASCGRKSKWGRSNPLPFGPFLAAAGFWCGWQTLASLTL
CHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA