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The map label for this gene is zntR [H]

Identifier: 238896789

GI number: 238896789

Start: 4770173

End: 4770598

Strand: Reverse

Name: zntR [H]

Synonym: KP1_5011

Alternate gene names: 238896789

Gene position: 4770598-4770173 (Counterclockwise)

Preceding gene: 238896790

Following gene: 238896788

Centisome position: 90.89

GC content: 53.05

Gene sequence:

>426_bases
ATGTATCGTATTGGTGAATTGGCAAAACTGGCTGACGTGACGCCTGATACCATCCGCTACTATGAAAAGCAGCAGATGAT
GGATCATGACATACGCACCGAGGGAGGATTTCGTCTGTACTCGGATAACGATCTTCAACGGCTGCGCTTTATTCGTTATG
CCCGACAACTGGGTTTCACCCTGGAAGCGATCCGCGAATTATTGTCGATCCGCATCGATCCGGAGCATCATACCTGTCAG
GAGTCGAAAGGGATCGTTCAGGCGCGATTAAGTGAAGTCGAGGCGCGGATTAAAGAGCTACAGACGATGCGCCGCTCTCT
GCAGCGGCTCAACGATGCCTGTTGCGGCACTGCCCACAGCAGCGTTTACTGTTCTATCCTTGAGGCCCTTGAACAAGGGG
CCAGCAACGGCAATGGCGGACGTTGA

Upstream 100 bases:

>100_bases
CCCTGCTCGAGCTGAAGTTACGTCAGGCAGGTCTGAACACCGACTTTTTACGCGGTGAGTACGCCGATGCGTTGCTGCAA
AAAATAAATCAGGAGTAAAT

Downstream 100 bases:

>100_bases
TTTTTTAAACGCGCGGATCTACACTCGCGCCGAGTTTATACATATACCGGAGTAACTATGAGTCGCTATCAGCATACTAA
AGGACAAATTAAAGATAACG

Product: zinc-responsive transcriptional regulator

Products: NA

Alternate protein names: Zn(II)-responsive regulator of zntA [H]

Number of amino acids: Translated: 141; Mature: 141

Protein sequence:

>141_residues
MYRIGELAKLADVTPDTIRYYEKQQMMDHDIRTEGGFRLYSDNDLQRLRFIRYARQLGFTLEAIRELLSIRIDPEHHTCQ
ESKGIVQARLSEVEARIKELQTMRRSLQRLNDACCGTAHSSVYCSILEALEQGASNGNGGR

Sequences:

>Translated_141_residues
MYRIGELAKLADVTPDTIRYYEKQQMMDHDIRTEGGFRLYSDNDLQRLRFIRYARQLGFTLEAIRELLSIRIDPEHHTCQ
ESKGIVQARLSEVEARIKELQTMRRSLQRLNDACCGTAHSSVYCSILEALEQGASNGNGGR
>Mature_141_residues
MYRIGELAKLADVTPDTIRYYEKQQMMDHDIRTEGGFRLYSDNDLQRLRFIRYARQLGFTLEAIRELLSIRIDPEHHTCQ
ESKGIVQARLSEVEARIKELQTMRRSLQRLNDACCGTAHSSVYCSILEALEQGASNGNGGR

Specific function: Zinc-responsive transcriptional regulator of zntA [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789687, Length=140, Percent_Identity=85, Blast_Score=254, Evalue=2e-69,
Organism=Escherichia coli, GI1786695, Length=127, Percent_Identity=36.2204724409449, Blast_Score=86, Evalue=9e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR015358
- InterPro:   IPR011788 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 16209; Mature: 16209

Theoretical pI: Translated: 7.45; Mature: 7.45

Prosite motif: PS00552 HTH_MERR_1 ; PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYRIGELAKLADVTPDTIRYYEKQQMMDHDIRTEGGFRLYSDNDLQRLRFIRYARQLGFT
CCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHCCH
LEAIRELLSIRIDPEHHTCQESKGIVQARLSEVEARIKELQTMRRSLQRLNDACCGTAHS
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
SVYCSILEALEQGASNGNGGR
HHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MYRIGELAKLADVTPDTIRYYEKQQMMDHDIRTEGGFRLYSDNDLQRLRFIRYARQLGFT
CCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHCCH
LEAIRELLSIRIDPEHHTCQESKGIVQARLSEVEARIKELQTMRRSLQRLNDACCGTAHS
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
SVYCSILEALEQGASNGNGGR
HHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]