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The map label for this gene is envR [H]

Identifier: 238896770

GI number: 238896770

Start: 4748900

End: 4749553

Strand: Reverse

Name: envR [H]

Synonym: KP1_4990

Alternate gene names: 238896770

Gene position: 4749553-4748900 (Counterclockwise)

Preceding gene: 238896774

Following gene: 238896758

Centisome position: 90.49

GC content: 51.22

Gene sequence:

>654_bases
ATGGCAAGAAAAACAAAAGAAGAGGCGCAGCGCACGCGGCAGCTCCTGATTGAGTCCGCAATCCAGCAGTTCGCCCTGCG
CGGAGTAACCAACACCACCCTGACGGATATCGCCGATGCGGCGGGAGTGACTCGCGGCGCGGTGTACTGGCATTTTGCCA
GTAAGACGGAGCTGTTTAATGAAATGTGGCAGCAGCAGCCGCCGCTTAGAGATTTGATTCAGCCCAGTCAGGCCATAGAG
TACGAACAGGAGCCGTTAAATGCTTTACGCGAGCGGTTTATTGCAGGCCTGCGCTATATTGCTGCGAATCCTCGACAGCG
CGCTCTGATGCAAATTCTTTATCAGCGCTGTGAGTTTTCCAGTGATATGCTTTCGGAATACGAAATTCGCCAACGTATTG
GTTTTAATTATTCACTCATTGGCGGCATCCTGCAGTGCTGCGTGCGTAACAATATATTGCCAGCCGAAACAAACATTGAG
ATGATATTAATTGTTTTACACAGTGCTTTTTCCGGGCTGATTAAAAACTGGCTGCTCGATCCGCAACGCTTCGATCTTTA
TCAGCAGGCGCCTGCGCTGGTGGATAATATAATGGCGGTGGTCTGTGCTGCGCGTTTATCGGGAGGGCCTGCGCTACGGC
TGGTGAATCAGTAA

Upstream 100 bases:

>100_bases
TTGTCTGCATTTTTGCTAAATAATACTTCATGGCAAATGCTAGATTAATTCTAATTAAGAATATCCTATATTATCTGCTT
ATCGGGAAGTGGGGCCTTGT

Downstream 100 bases:

>100_bases
TGAGTTCTGTTGGCGCAGATAATAAAAAAGGCGCTTCCCCATGCCGAAGAGCGCCTTTTATATCAAGCAAGCAACTGACT
AGTATCAGTTCATGCCGTAT

Product: DNA-binding transcriptional regulator EnvR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 217; Mature: 216

Protein sequence:

>217_residues
MARKTKEEAQRTRQLLIESAIQQFALRGVTNTTLTDIADAAGVTRGAVYWHFASKTELFNEMWQQQPPLRDLIQPSQAIE
YEQEPLNALRERFIAGLRYIAANPRQRALMQILYQRCEFSSDMLSEYEIRQRIGFNYSLIGGILQCCVRNNILPAETNIE
MILIVLHSAFSGLIKNWLLDPQRFDLYQQAPALVDNIMAVVCAARLSGGPALRLVNQ

Sequences:

>Translated_217_residues
MARKTKEEAQRTRQLLIESAIQQFALRGVTNTTLTDIADAAGVTRGAVYWHFASKTELFNEMWQQQPPLRDLIQPSQAIE
YEQEPLNALRERFIAGLRYIAANPRQRALMQILYQRCEFSSDMLSEYEIRQRIGFNYSLIGGILQCCVRNNILPAETNIE
MILIVLHSAFSGLIKNWLLDPQRFDLYQQAPALVDNIMAVVCAARLSGGPALRLVNQ
>Mature_216_residues
ARKTKEEAQRTRQLLIESAIQQFALRGVTNTTLTDIADAAGVTRGAVYWHFASKTELFNEMWQQQPPLRDLIQPSQAIEY
EQEPLNALRERFIAGLRYIAANPRQRALMQILYQRCEFSSDMLSEYEIRQRIGFNYSLIGGILQCCVRNNILPAETNIEM
ILIVLHSAFSGLIKNWLLDPQRFDLYQQAPALVDNIMAVVCAARLSGGPALRLVNQ

Specific function: Potential regulator protein for the acrEF/envCD genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789664, Length=198, Percent_Identity=53.030303030303, Blast_Score=232, Evalue=1e-62,
Organism=Escherichia coli, GI1786669, Length=192, Percent_Identity=39.5833333333333, Blast_Score=146, Evalue=1e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR013572
- InterPro:   IPR001647 [H]

Pfam domain/function: PF08361 TetR_C_2; PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 24729; Mature: 24598

Theoretical pI: Translated: 7.93; Mature: 7.93

Prosite motif: PS01081 HTH_TETR_1 ; PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARKTKEEAQRTRQLLIESAIQQFALRGVTNTTLTDIADAAGVTRGAVYWHFASKTELFN
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHEEEHHHHHHHHH
EMWQQQPPLRDLIQPSQAIEYEQEPLNALRERFIAGLRYIAANPRQRALMQILYQRCEFS
HHHHCCCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCC
SDMLSEYEIRQRIGFNYSLIGGILQCCVRNNILPAETNIEMILIVLHSAFSGLIKNWLLD
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
PQRFDLYQQAPALVDNIMAVVCAARLSGGPALRLVNQ
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCC
>Mature Secondary Structure 
ARKTKEEAQRTRQLLIESAIQQFALRGVTNTTLTDIADAAGVTRGAVYWHFASKTELFN
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHEEEHHHHHHHHH
EMWQQQPPLRDLIQPSQAIEYEQEPLNALRERFIAGLRYIAANPRQRALMQILYQRCEFS
HHHHCCCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCC
SDMLSEYEIRQRIGFNYSLIGGILQCCVRNNILPAETNIEMILIVLHSAFSGLIKNWLLD
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
PQRFDLYQQAPALVDNIMAVVCAARLSGGPALRLVNQ
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]