Click here to switch to the map view.

The map label for this gene is tldD [H]

Identifier: 238896750

GI number: 238896750

Start: 4727579

End: 4729024

Strand: Reverse

Name: tldD [H]

Synonym: KP1_4969

Alternate gene names: 238896750

Gene position: 4729024-4727579 (Counterclockwise)

Preceding gene: 238896751

Following gene: 238896748

Centisome position: 90.1

GC content: 61.13

Gene sequence:

>1446_bases
ATGAGTCTGAACCTGGTAAGTGAACAATTACTGTCGGCAAATGGCCTGAATCATCAGGACCTGTTTGCCATTCTTGGTCA
ACTGACCGAGCGCCGCCTCGATTACGGCGATCTCTATTTTCAGTCGAGCTATCACGAATCCTGGGTTCTGGAAGACAGCA
TCATTAAAGATGGGTCGTACAATATCGACCAGGGCGTAGGCGTGCGCGCCGTCAGCGGCGAAAAAACGGGCTTTGCCTAC
GCCGATCAGATCAGCAAACTGGCGCTGGAGCAGAGCGCCCAGGCGGCGCGGACCATTGTGCGCGACACCGGCAATGGCAA
AGTGCAGACCCTCGGCGCCGTAGAGCATCGTGCCCTGTACACCAGCATCGACCCGCTGCAGAGTATGACCCGGGAAGAGA
AGCTGGATATTCTGCGCCGGGTAGACAAAGTCGCCCGGGCGGCGGACCAGCGGGTGCAGGAGGTTTCAGCCAGCCTGAGC
GGGGTGTATGAGCTGATCCTGGTCGCCGCCACCGATGGCACTCTGGCCGCCGACGTTCGTCCGCTGGTTCGTCTTTCCGT
CAGCGTGCTGGTGGAAGAGGATGGCAAGCGTGAGCGCGGCAGCAGCGGCGGTGGCGGGCGTTTTGGTTATGACTATTTCC
TCGCCTCCCAGGAGGGCGACGTGCGGGCTGATGCCTGGGCGAAAGAAGCGGTGCGCATGGCGCTGGTCAACCTCTCGGCG
GTCGCCGCCCCTGCGGGGATGCTGCCGGTGGTGCTCGGCGCCGGCTGGCCTGGCGTCCTGCTGCATGAAGCGGTCGGCCA
TGGGCTGGAAGGCGATTTCAACCGGCGTGGCACCTCGGTCTTTAGCGGCCATATGGGGGAATTAGTCGCCTCTGAGCTGT
GCACCGTAGTGGATGACGGCACCATCGCCGATCGCCGTGGCTCGGTGGCCATTGATGACGAAGGGACGCCGGGGCAATAC
AACGTGCTGATCGAAAACGGCATTCTGAAAGGCTATATGCAGGATAAACTCAACGCGCGCCTGATGGGCGTCGCACCGAC
AGGCAATGGCCGACGTGAGTCGTATGCCCATCTGCCGATGCCGCGTATGACCAACACCTATATGCTGGCGGGCCAGTCGA
CGCCACAGGAGATTATCGAATCGGTCGACTACGGTATCTTTGCGCCTAACTTCGGCGGCGGGCAGGTGGATATCACCTCC
GGTAAATTCGTCTTTTCCACTTCCGAGGCCTATCTGATCGAAAAAGGGAAGGTCACGAAGGCGGTGAAAGGGGCCACGCT
GATTGGCTCCGGCATTGAGACCATGCAGCAGATTTCGATGGTGGGCAACGACCTGCGCCTGGATAACGGCGTCGGCGTCT
GTGGCAAAGAGGGCCAGAGCGTGCCGGTGGGCGTCGGCCAGCCGACCCTGAAGGTCGATAACCTTACCGTCGGCGGCACC
GCCTGA

Upstream 100 bases:

>100_bases
AAAAAGCAATGATTTGACGATTGCCGGGAATTGCCGCAATCTCAATAGATAGCCTTCTGTATTTCCGCCTGTCAGGCGGC
AACAAACGAGTAGCATAACG

Downstream 100 bases:

>100_bases
TCCTGACCTGGTTCCCGGCGCTGCCGGGAACCGCTTCACCGGGCGATCCCGCGCCCGTGCATGCCCTGATAGATCTTCGC
CACGTCGACAAAATACTCCG

Product: protease TldD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 481; Mature: 480

Protein sequence:

>481_residues
MSLNLVSEQLLSANGLNHQDLFAILGQLTERRLDYGDLYFQSSYHESWVLEDSIIKDGSYNIDQGVGVRAVSGEKTGFAY
ADQISKLALEQSAQAARTIVRDTGNGKVQTLGAVEHRALYTSIDPLQSMTREEKLDILRRVDKVARAADQRVQEVSASLS
GVYELILVAATDGTLAADVRPLVRLSVSVLVEEDGKRERGSSGGGGRFGYDYFLASQEGDVRADAWAKEAVRMALVNLSA
VAAPAGMLPVVLGAGWPGVLLHEAVGHGLEGDFNRRGTSVFSGHMGELVASELCTVVDDGTIADRRGSVAIDDEGTPGQY
NVLIENGILKGYMQDKLNARLMGVAPTGNGRRESYAHLPMPRMTNTYMLAGQSTPQEIIESVDYGIFAPNFGGGQVDITS
GKFVFSTSEAYLIEKGKVTKAVKGATLIGSGIETMQQISMVGNDLRLDNGVGVCGKEGQSVPVGVGQPTLKVDNLTVGGT
A

Sequences:

>Translated_481_residues
MSLNLVSEQLLSANGLNHQDLFAILGQLTERRLDYGDLYFQSSYHESWVLEDSIIKDGSYNIDQGVGVRAVSGEKTGFAY
ADQISKLALEQSAQAARTIVRDTGNGKVQTLGAVEHRALYTSIDPLQSMTREEKLDILRRVDKVARAADQRVQEVSASLS
GVYELILVAATDGTLAADVRPLVRLSVSVLVEEDGKRERGSSGGGGRFGYDYFLASQEGDVRADAWAKEAVRMALVNLSA
VAAPAGMLPVVLGAGWPGVLLHEAVGHGLEGDFNRRGTSVFSGHMGELVASELCTVVDDGTIADRRGSVAIDDEGTPGQY
NVLIENGILKGYMQDKLNARLMGVAPTGNGRRESYAHLPMPRMTNTYMLAGQSTPQEIIESVDYGIFAPNFGGGQVDITS
GKFVFSTSEAYLIEKGKVTKAVKGATLIGSGIETMQQISMVGNDLRLDNGVGVCGKEGQSVPVGVGQPTLKVDNLTVGGT
A
>Mature_480_residues
SLNLVSEQLLSANGLNHQDLFAILGQLTERRLDYGDLYFQSSYHESWVLEDSIIKDGSYNIDQGVGVRAVSGEKTGFAYA
DQISKLALEQSAQAARTIVRDTGNGKVQTLGAVEHRALYTSIDPLQSMTREEKLDILRRVDKVARAADQRVQEVSASLSG
VYELILVAATDGTLAADVRPLVRLSVSVLVEEDGKRERGSSGGGGRFGYDYFLASQEGDVRADAWAKEAVRMALVNLSAV
AAPAGMLPVVLGAGWPGVLLHEAVGHGLEGDFNRRGTSVFSGHMGELVASELCTVVDDGTIADRRGSVAIDDEGTPGQYN
VLIENGILKGYMQDKLNARLMGVAPTGNGRRESYAHLPMPRMTNTYMLAGQSTPQEIIESVDYGIFAPNFGGGQVDITSG
KFVFSTSEAYLIEKGKVTKAVKGATLIGSGIETMQQISMVGNDLRLDNGVGVCGKEGQSVPVGVGQPTLKVDNLTVGGTA

Specific function: Suppresses the inhibitory activity of the carbon storage regulator (CsrA) [H]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=481, Percent_Identity=92.0997920997921, Blast_Score=877, Evalue=0.0,
Organism=Escherichia coli, GI1790682, Length=407, Percent_Identity=20.6388206388206, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 51236; Mature: 51105

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLNLVSEQLLSANGLNHQDLFAILGQLTERRLDYGDLYFQSSYHESWVLEDSIIKDGSY
CCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCEEECHHHCCCCCC
NIDQGVGVRAVSGEKTGFAYADQISKLALEQSAQAARTIVRDTGNGKVQTLGAVEHRALY
CCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECHHHHHHHH
TSIDPLQSMTREEKLDILRRVDKVARAADQRVQEVSASLSGVYELILVAATDGTLAADVR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCHHHHH
PLVRLSVSVLVEEDGKRERGSSGGGGRFGYDYFLASQEGDVRADAWAKEAVRMALVNLSA
HHHHHEEEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHH
VAAPAGMLPVVLGAGWPGVLLHEAVGHGLEGDFNRRGTSVFSGHMGELVASELCTVVDDG
HHCCCCCHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHCCC
TIADRRGSVAIDDEGTPGQYNVLIENGILKGYMQDKLNARLMGVAPTGNGRRESYAHLPM
CEECCCCCEEECCCCCCCEEEEEEECCHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCC
PRMTNTYMLAGQSTPQEIIESVDYGIFAPNFGGGQVDITSGKFVFSTSEAYLIEKGKVTK
CCCCCEEEEECCCCHHHHHHHCCCCEECCCCCCCEEEEECCEEEEECCCEEEEECCCHHH
AVKGATLIGSGIETMQQISMVGNDLRLDNGVGVCGKEGQSVPVGVGQPTLKVDNLTVGGT
HHCCCCEECCHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCCCEEECCEECCCC
A
C
>Mature Secondary Structure 
SLNLVSEQLLSANGLNHQDLFAILGQLTERRLDYGDLYFQSSYHESWVLEDSIIKDGSY
CCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCEEECHHHCCCCCC
NIDQGVGVRAVSGEKTGFAYADQISKLALEQSAQAARTIVRDTGNGKVQTLGAVEHRALY
CCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECHHHHHHHH
TSIDPLQSMTREEKLDILRRVDKVARAADQRVQEVSASLSGVYELILVAATDGTLAADVR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCHHHHH
PLVRLSVSVLVEEDGKRERGSSGGGGRFGYDYFLASQEGDVRADAWAKEAVRMALVNLSA
HHHHHEEEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHH
VAAPAGMLPVVLGAGWPGVLLHEAVGHGLEGDFNRRGTSVFSGHMGELVASELCTVVDDG
HHCCCCCHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHCCC
TIADRRGSVAIDDEGTPGQYNVLIENGILKGYMQDKLNARLMGVAPTGNGRRESYAHLPM
CEECCCCCEEECCCCCCCEEEEEEECCHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCC
PRMTNTYMLAGQSTPQEIIESVDYGIFAPNFGGGQVDITSGKFVFSTSEAYLIEKGKVTK
CCCCCEEEEECCCCHHHHHHHCCCCEECCCCCCCEEEEECCEEEEECCCEEEEECCCHHH
AVKGATLIGSGIETMQQISMVGNDLRLDNGVGVCGKEGQSVPVGVGQPTLKVDNLTVGGT
HHCCCCEECCHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCCCEEECCEECCCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]